PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: thrombolytic drug pathway
Accession: PW:0002152
browse the term
Definition: The pharmacokinetics and pharmacodynamics of drugs that can dissolve blood clots. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
G
Col1a1
collagen type I alpha 1 chain
ISO
SMPDB
SMP:00280
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
F10
coagulation factor X
ISO
SMPDB
SMP:00280
NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
G
F11
coagulation factor XI
ISO
SMPDB
SMP:00280
NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437
G
F12
coagulation factor XII
ISO
SMPDB
SMP:00280
NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
G
F13a1
coagulation factor XIII A1 chain
ISO
SMPDB
SMP:00280
NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
G
F13b
coagulation factor XIII B chain
ISO
SMPDB
SMP:00280
NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381
G
F2
coagulation factor II, thrombin
ISO
SMPDB
SMP:00280
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
G
F3
coagulation factor III, tissue factor
ISO
SMPDB
SMP:00280
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
F5
coagulation factor V
ISO
SMPDB
SMP:00280
NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
G
F7
coagulation factor VII
ISO
SMPDB
SMP:00280
NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
G
F8
coagulation factor VIII
ISO
SMPDB
SMP:00280
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
G
F9
coagulation factor IX
ISO
SMPDB
SMP:00280
NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835
G
Fga
fibrinogen alpha chain
ISO
SMPDB
SMP:00280
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
G
Fgb
fibrinogen beta chain
ISO
SMPDB
SMP:00280
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
G
Fgg
fibrinogen gamma chain
ISO
SMPDB
SMP:00280
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
G
Ggcx
gamma-glutamyl carboxylase
ISO
SMPDB
SMP:00280
NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
G
Klkb1
kallikrein B1
ISO
SMPDB
SMP:00280
NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053
G
Plat
plasminogen activator, tissue type
ISO
SMPDB
SMP:00280
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
G
Plg
plasminogen
ISO
SMPDB
SMP:00280
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
G
Vkorc1
vitamin K epoxide reductase complex, subunit 1
ISO
SMPDB
SMP:00280
NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008
G
Col1a1
collagen type I alpha 1 chain
ISO
SMPDB
SMP:00281
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
F10
coagulation factor X
ISO
SMPDB
SMP:00281
NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
G
F11
coagulation factor XI
ISO
SMPDB
SMP:00281
NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437
G
F12
coagulation factor XII
ISO
SMPDB
SMP:00281
NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
G
F13a1
coagulation factor XIII A1 chain
ISO
SMPDB
SMP:00281
NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
G
F13b
coagulation factor XIII B chain
ISO
SMPDB
SMP:00281
NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381
G
F2
coagulation factor II, thrombin
ISO
SMPDB
SMP:00281
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
G
F3
coagulation factor III, tissue factor
ISO
SMPDB
SMP:00281
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
F5
coagulation factor V
ISO
SMPDB
SMP:00281
NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
G
F7
coagulation factor VII
ISO
SMPDB
SMP:00281
NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
G
F8
coagulation factor VIII
ISO
SMPDB
SMP:00281
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
G
F9
coagulation factor IX
ISO
SMPDB
SMP:00281
NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835
G
Fga
fibrinogen alpha chain
ISO
SMPDB
SMP:00281
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
G
Fgb
fibrinogen beta chain
ISO
SMPDB
SMP:00281
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
G
Fgg
fibrinogen gamma chain
ISO
SMPDB
SMP:00281
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
G
Ggcx
gamma-glutamyl carboxylase
ISO
SMPDB
SMP:00281
NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
G
Klkb1
kallikrein B1
ISO
SMPDB
SMP:00281
NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053
G
Plat
plasminogen activator, tissue type
ISO
SMPDB
SMP:00281
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
G
Plg
plasminogen
ISO
SMPDB
SMP:00281
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
G
Vkorc1
vitamin K epoxide reductase complex, subunit 1
ISO
SMPDB
SMP:00281
NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008
G
Col1a1
collagen type I alpha 1 chain
ISO
SMPDB
SMP:00285
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
F10
coagulation factor X
ISO
SMPDB
SMP:00285
NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
G
F11
coagulation factor XI
ISO
SMPDB
SMP:00285
NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437
G
F12
coagulation factor XII
ISO
SMPDB
SMP:00285
NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
G
F13a1
coagulation factor XIII A1 chain
ISO
SMPDB
SMP:00285
NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
G
F13b
coagulation factor XIII B chain
ISO
SMPDB
SMP:00285
NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381
G
F2
coagulation factor II, thrombin
ISO
SMPDB
SMP:00285
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
G
F3
coagulation factor III, tissue factor
ISO
SMPDB
SMP:00285
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
F5
coagulation factor V
ISO
SMPDB
SMP:00285
NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
G
F7
coagulation factor VII
ISO
SMPDB
SMP:00285
NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
G
F8
coagulation factor VIII
ISO
SMPDB
SMP:00285
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
G
F9
coagulation factor IX
ISO
SMPDB
SMP:00285
NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835
G
Fga
fibrinogen alpha chain
ISO
SMPDB
SMP:00285
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
G
Fgb
fibrinogen beta chain
ISO
SMPDB
SMP:00285
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
G
Fgg
fibrinogen gamma chain
ISO
SMPDB
SMP:00285
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
G
Ggcx
gamma-glutamyl carboxylase
ISO
SMPDB
SMP:00285
NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
G
Klkb1
kallikrein B1
ISO
SMPDB
SMP:00285
NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053
G
Plat
plasminogen activator, tissue type
ISO
SMPDB
SMP:00285
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
G
Plg
plasminogen
ISO
SMPDB
SMP:00285
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
G
Vkorc1
vitamin K epoxide reductase complex, subunit 1
ISO
SMPDB
SMP:00285
NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all