PLG (plasminogen) - Rat Genome Database

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Gene: PLG (plasminogen) Sus scrofa
Analyze
Symbol: PLG
Name: plasminogen
RGD ID: 14106484
Description: ENCODES a protein that exhibits apolipoprotein binding (ortholog); chaperone binding (ortholog); endopeptidase activity (ortholog); INVOLVED IN biological process involved in interaction with symbiont (ortholog); extracellular matrix disassembly (ortholog); labyrinthine layer blood vessel development (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH acute kidney failure (ortholog); atypical hemolytic-uremic syndrome (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cell surface (ortholog); extracellular space (ortholog); extrinsic component of external side of plasma membrane (ortholog); INTERACTS WITH amiloride; crocidolite asbestos; serpentine asbestos
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,061,191 - 7,110,555 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,062,399 - 7,109,521 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218,740,127 - 8,787,546 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:14681463   PMID:14688145   PMID:17145712   PMID:22177313  


Genomics

Comparative Map Data
PLG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,061,191 - 7,110,555 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,062,399 - 7,109,521 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218,740,127 - 8,787,546 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6160,702,238 - 160,754,097 (+)EnsemblGRCh38hg38GRCh38
GRCh386160,702,193 - 160,754,097 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376161,123,225 - 161,175,129 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366161,043,273 - 161,094,328 (+)NCBINCBI36hg18NCBI36
Build 346161,093,693 - 161,144,749NCBI
Celera6161,842,077 - 161,894,063 (+)NCBI
Cytogenetic Map6q26NCBI
HuRef6158,568,041 - 158,620,052 (+)NCBIHuRef
CHM1_16161,385,876 - 161,437,750 (+)NCBICHM1_1
Plg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,597,496 - 12,638,271 (+)NCBIGRCm39mm39
GRCm39 Ensembl1712,597,495 - 12,638,272 (+)Ensembl
GRCm381712,378,609 - 12,419,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,378,608 - 12,419,385 (+)EnsemblGRCm38mm10GRCm38
MGSCv371712,571,475 - 12,612,250 (+)NCBIGRCm37mm9NCBIm37
MGSCv361712,221,966 - 12,262,743 (+)NCBImm8
Celera1712,409,327 - 12,450,146 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.5NCBI
Plg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2148,325,186 - 48,367,643 (-)NCBI
Rnor_6.0 Ensembl148,521,772 - 48,563,776 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0148,521,828 - 48,563,895 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0151,192,273 - 51,233,898 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,782,464 - 42,825,149 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,785,408 - 42,828,097 (-)NCBI
Celera144,117,228 - 44,159,691 (-)NCBICelera
Cytogenetic Map1q11NCBI
Plg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543920,317,552 - 20,366,475 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543920,317,814 - 20,366,724 (+)NCBIChiLan1.0ChiLan1.0
LOC100982214
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16163,674,142 - 163,722,630 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6163,673,464 - 163,736,777 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06158,662,192 - 158,713,413 (+)NCBIMhudiblu_PPA_v0panPan3
PLG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,497,229 - 49,535,260 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl149,497,229 - 49,535,260 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha150,340,229 - 50,378,262 (-)NCBI
ROS_Cfam_1.0149,682,496 - 49,720,525 (-)NCBI
UMICH_Zoey_3.1149,564,853 - 49,602,878 (-)NCBI
UNSW_CanFamBas_1.0149,436,580 - 49,474,619 (-)NCBI
UU_Cfam_GSD_1.0150,051,672 - 50,089,725 (-)NCBI
Plg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,523,021 - 144,556,568 (-)NCBI
SpeTri2.0NW_00493648911,775,243 - 11,808,482 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11388,266,054 - 88,321,596 (+)NCBI
ChlSab1.1 Ensembl1388,268,198 - 88,322,644 (+)Ensembl
Vero_WHO_p1.0NW_02366604060,598,947 - 60,654,431 (+)NCBI
Plg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248552,362,793 - 2,401,519 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system musculoskeletal system nervous system renal system
High
Medium
Low 1
Below cutoff 1 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000004466   ⟹   ENSSSCP00000004364
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,062,397 - 7,109,533 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000055744   ⟹   ENSSSCP00000038571
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,061,191 - 7,109,518 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000067197   ⟹   ENSSSCP00000061911
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,062,437 - 7,110,555 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000074765   ⟹   ENSSSCP00000069662
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,062,437 - 7,110,555 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000076640   ⟹   ENSSSCP00000071429
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,062,437 - 7,110,555 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000088617   ⟹   ENSSSCP00000067714
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,066,240 - 7,110,555 (+)Ensembl
RefSeq Acc Id: NM_001044590   ⟹   NP_001038055
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.117,062,399 - 7,109,521 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001038055 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABF82358 (Get FASTA)   NCBI Sequence Viewer  
  P06867 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001038055   ⟸   NM_001044590
- Peptide Label: precursor
- UniProtKB: P06867 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067714   ⟸   ENSSSCT00000088617
RefSeq Acc Id: ENSSSCP00000038571   ⟸   ENSSSCT00000055744
RefSeq Acc Id: ENSSSCP00000069662   ⟸   ENSSSCT00000074765
RefSeq Acc Id: ENSSSCP00000071429   ⟸   ENSSSCT00000076640
RefSeq Acc Id: ENSSSCP00000004364   ⟸   ENSSSCT00000004466
RefSeq Acc Id: ENSSSCP00000061911   ⟸   ENSSSCT00000067197
Protein Domains
Apple   Kringle   PAN   Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004038 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070026984 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000004364 UniProtKB/TrEMBL
  ENSSSCP00000038571 UniProtKB/TrEMBL
  ENSSSCP00000061911 UniProtKB/TrEMBL
  ENSSSCP00000067714 UniProtKB/TrEMBL
  ENSSSCP00000069662 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000071429 UniProtKB/TrEMBL
  ENSSSCP00070045873 UniProtKB/TrEMBL
  ENSSSCP00070045874 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004466 UniProtKB/TrEMBL
  ENSSSCT00000055744 UniProtKB/TrEMBL
  ENSSSCT00000067197 UniProtKB/TrEMBL
  ENSSSCT00000074765 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000076640 UniProtKB/TrEMBL
  ENSSSCT00000088617 UniProtKB/TrEMBL
  ENSSSCT00070054110 UniProtKB/TrEMBL
  ENSSSCT00070054111 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro HGF-like UniProtKB/TrEMBL
  Kringle UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pan_app UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_S1A_plasmin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:733660 UniProtKB/Swiss-Prot
NCBI Gene PLG ENTREZGENE
Pfam Kringle UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF HGF_MST1 UniProtKB/TrEMBL
  Plasmin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE KRINGLE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRINGLE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PAN_AP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287A481_PIG UniProtKB/TrEMBL
  A0A4X1VQL9_PIG UniProtKB/TrEMBL
  A0A4X1VW72_PIG UniProtKB/TrEMBL
  A0A5G2QU84_PIG UniProtKB/TrEMBL
  A0A5G2QUR5_PIG UniProtKB/TrEMBL
  A0A5G2QXR3_PIG UniProtKB/TrEMBL
  A0A5G2R2W1_PIG UniProtKB/TrEMBL
  F1SB81_PIG UniProtKB/TrEMBL
  P06867 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q19AZ9 UniProtKB/Swiss-Prot