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Gene: GGCX (gamma-glutamyl carboxylase) Sus scrofa

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Symbol:

GGCX

Name:

gamma-glutamyl carboxylase

RGD ID:

14031902

Description:

ENCODES a protein that exhibits gamma-glutamyl carboxylase activity (ortholog); vitamin binding (ortholog); INVOLVED IN lung growth (ortholog); peptidyl-glutamic acid carboxylation (ortholog); response to dexamethasone (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH blood coagulation disease (ortholog); Coagulation Protein Disorders (ortholog); combined deficiency of vitamin K-dependent clotting factors 1 (ortholog); FOUND IN endoplasmic reticulum lumen (ortholog); endoplasmic reticulum membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

vitamin K-dependent gamma-carboxylase

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GGCX (gamma-glutamyl carboxylase)	HGNC	EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Ggcx (gamma-glutamyl carboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ggcx (gamma-glutamyl carboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ggcx (gamma-glutamyl carboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GGCX (gamma-glutamyl carboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GGCX (gamma-glutamyl carboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ggcx (gamma-glutamyl carboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GGCX (gamma-glutamyl carboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ggcx (gamma-glutamyl carboxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	59,202,429 - 59,218,145 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	59,202,363 - 59,219,807 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	62,263,519 - 62,276,716 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

blood coagulation disease (ISO)

Coagulation Protein Disorders (ISO)

combined deficiency of vitamin K-dependent clotting factors 1 (ISO)

coronary artery disease (ISO)

genetic disease (ISO)

hemorrhagic disease (ISO)

hereditary spastic paraplegia 31 (ISO)

Inherited Blood Coagulation Disease (ISO)

Pseudoxanthoma Elasticum-Like Disorder with Multiple Coagulation Factor Deficiency (ISO)

thrombocytopenia (ISO)

urolithiasis (ISO)

vitamin K deficiency bleeding (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lung growth (ISO)

peptidyl-glutamic acid carboxylation (ISO)

protein maturation (IEA)

response to dexamethasone (ISO)

response to manganese ion (ISO)

response to oxygen levels (ISO)

response to parathyroid hormone (ISO)

response to Thyroglobulin triiodothyronine (ISO)

response to vitamin D (ISO)

response to vitamin K (ISO)

vitamin K metabolic process (IBA,IEA)

Cellular Component

endomembrane system (IEA)

endoplasmic reticulum lumen (IEA,ISO)

endoplasmic reticulum membrane (IEA,ISO)

membrane (IEA)

Molecular Function

gamma-glutamyl carboxylase activity (IBA,IEA,ISO)

lyase activity (IEA)

vitamin binding (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acenocoumarol pharmacodynamics pathway (ISO)

alteplase pharmacodynamics pathway (ISO)

aminocaproic acid pharmacodynamics pathway (ISO)

anistreplase pharmacodynamics pathway (ISO)

aprotinin pharmacodynamics pathway (ISO)

argatroban pharmacodynamics pathway (ISO)

bivalirudin pharmacodynamics pathway (ISO)

dicoumarol pharmacodynamics pathway (ISO)

enoxaparin pharmacodynamics pathway (ISO)

fondaparinux pharmacodynamics pathway (ISO)

heparin pharmacodynamics pathway (ISO)

phenindione pharmacodynamics pathway (ISO)

reteplase pharmacodynamics pathway (ISO)

tranexamic acid pharmacodynamics pathway (ISO)

vitamin K cycle pathway (ISO)

vitamin K metabolic pathway (ISO)

warfarin pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GGCX
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	59,202,429 - 59,218,145 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	59,202,363 - 59,219,807 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	62,263,519 - 62,276,716 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GGCX
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	85,544,720 - 85,561,493 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	85,544,720 - 85,561,532 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	85,771,843 - 85,788,616 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	85,629,714 - 85,642,090 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	85,687,861 - 85,700,237	NCBI
Celera	2	85,604,381 - 85,616,845 (-)	NCBI		Celera
Cytogenetic Map	2	p11.2	NCBI
HuRef	2	85,669,320 - 85,686,004 (-)	NCBI		HuRef
CHM1_1	2	85,701,785 - 85,718,463 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	85,546,779 - 85,563,552 (-)	NCBI		T2T-CHM13v2.0

Ggcx
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	72,391,262 - 72,407,696 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	72,391,291 - 72,407,695 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	72,414,279 - 72,433,359 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	72,414,308 - 72,430,712 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	72,364,327 - 72,380,701 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	72,343,842 - 72,360,216 (+)	NCBI		MGSCv36	mm8
Celera	6	74,509,409 - 74,525,757 (+)	NCBI		Celera
Cytogenetic Map	6	C1	NCBI
cM Map	6	32.27	NCBI

Ggcx
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	106,027,918 - 106,043,653 (+)	NCBI		GRCr8
mRatBN7.2	4	104,469,737 - 104,485,631 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	104,469,765 - 104,487,063 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	109,849,413 - 109,865,120 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	105,624,526 - 105,640,233 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	104,237,548 - 104,253,262 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	100,277,345 - 100,293,097 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	100,277,391 - 100,293,250 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	165,047,672 - 165,063,604 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	105,719,323 - 105,735,037 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	105,963,803 - 105,979,517 (+)	NCBI
Celera	4	93,622,596 - 93,638,331 (+)	NCBI		Celera
Cytogenetic Map	4	q32	NCBI

Ggcx
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	1,936,772 - 1,952,635 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	1,926,924 - 1,952,635 (+)	NCBI	ChiLan1.0	ChiLan1.0

GGCX
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	40,819,956 - 40,833,578 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	40,822,718 - 40,836,051 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	85,599,227 - 85,612,274 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	87,152,108 - 87,164,567 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	87,152,111 - 87,164,567 (-)	Ensembl	panpan1.1		panPan2

GGCX
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	39,512,293 - 39,525,251 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	39,512,387 - 39,529,121 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	39,183,664 - 39,196,637 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	40,258,976 - 40,271,953 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	40,259,006 - 40,275,813 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	39,388,607 - 39,401,574 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	39,460,505 - 39,473,477 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	39,860,352 - 39,873,319 (+)	NCBI		UU_Cfam_GSD_1.0

Ggcx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	79,147,378 - 79,158,577 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936712	1,699,750 - 1,709,087 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936712	1,696,264 - 1,709,087 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GGCX
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	21,593,202 - 21,605,800 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	21,593,088 - 21,604,885 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	90,859,363 - 90,872,520 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ggcx
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624749	17,579,661 - 17,593,150 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624749	17,579,690 - 17,595,111 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in GGCX
362 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003354744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP325280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01027256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000031020 ⟹ ENSSSCP00000021229

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	59,202,429 - 59,218,145 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000079244 ⟹ ENSSSCP00000072334

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	59,202,450 - 59,217,250 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000080468 ⟹ ENSSSCP00000060390

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	59,202,430 - 59,217,239 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000089421 ⟹ ENSSSCP00000063000

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	59,202,377 - 59,221,132 (+)	Ensembl

RefSeq Acc Id:

XM_003354744 ⟹ XP_003354792

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	3	59,202,363 - 59,219,807 (+)	NCBI

Sequence:

show sequence

GGGCGCTTTCCGGCTCGCCTCGCAGGTGCTGATGTGTCGGGGAGGCGGGGCTTGGGGGAGCCAG
TCCCTGCGACGCTCCCTGCTCCGACGTGCAGCTGTGGTGGATCTAGCTCCCCGAGGCCATGGGG
GTGTCTGCTCGGTCCGCGCGGGCCCAGCCCCACTCTGATAAAGTACAGAAAGACAAGTCTGGAC
AGACCTCAGGGCCCCCTCAGAGCAGCCGAATGGGGAAACTCTTGGGTTTTGAGTGGACAGATGT
GTCCAGCTGGGGGAGACTGGTGACCCTGCTGAATAGACCAACGGATCCTGCAAGCCTGGCAGTC
TTCCGTTTTCTCTTTGGGCTGTTGATGGTGCTGGACATTCCCCAGGAGCGGGGGCTCAGCTCCC
TGGACCGAAGATACCTGGATGGGCTGGAGGTTTGCCGCTTCCCTTTGCTGGATGCCCTGCAGCC
ACTGCCACTTGACTGGATGTATCTTGTCTACACCATCATGTTTCTGGGGGCACTGGGCATGATG
CTGGGCCTGTGCTACCGGATAAGCTGTGTGTTATTCCTGCTGCCATACTGGTATGTGTTTCTCC
TGGACAAGACGTCGTGGAACAACCACTCCTATCTGTATGGTTTGCTGGCCTTTCAGCTGACGTT
CGTCGACGCAAACCGCTACTGGTCTGTGGACGGCCTGCTGAGCAGCCGGAAGCGGAATGCCCAC
GTGCCCCTCTGGAATTATGCTGTGCTGCGTGGCCAGATCTTCATTGTGTACTTCATTGCGGGCG
TGAAAAAGCTGGACGCTGACTGGGTGGAAGGCTACTCCATGGAGTACCTGTCCCGGCACTGGCT
CTTCAGTCCCTTCAAACTTGTGTTGTCCGAGGAGATGACGAGTCTGCTGGTGGTGCACTGGTGT
GGGCTGCTGCTCGACCTCTCAGCGGGTTTCCTGCTCTTCTTTGATGCCACAAGATCCATCGGCC
TCCTCTTCGTGTCCTACTTCCACTGCATGAATTCCCAGCTTTTCAGCATTGGAATGTTCCCGTA
TGTCATGCTGGCCAGCAGCCCTCTCTTCTGCTCCCCCGGTTGGCCTCGGAAGCTGGTGGCTCAC
TGCCCAAAAAGGCTGCAAGACCTGCTGCCCCTCAGGATTGCCCCTCAGCCCAGTGCCTCCTGCA
TGTACAAGAGGAGTCGGGCCAGAGGAGGCCAGAAGCCAGGGCTGCGCCATCGCCTGGGTGCCGC
CTTCACCCTGCTCTACCTCCTGGAACAGCTCTTCCTGCCCTATTCCCATTTCCTTACCCAGGGC
TATAACAATTGGACGAATGGGCTGTACGGCTACTCCTGGGACATGATGGTGCACTCCCGCTCCC
ACCAGCATGTCAAGATCACCTACCGTGACGGTCGCACCGGAGAGCTGGGCTACTTGAACCCTGG
GGTATTCACACAGAGCCGGCGTTGGAAGGATCATGCAGACATGCTGAAGCAATATGCCACTTGC
CTGAGCCGCCTGCTTCCCAAGTACAATGTCACTGAGCCCCAGATCTACTTTGATATTTGGGTCT
CCATCAATGACCGCTTCCAGCAGAGGATTTTTGACCCTCGCGTGGACATTGTGCAGGCTGCCTG
GTCCCCCTTCCAGCGCACACCTTGGCTGCAGCCACTGTTGATGGGCCTGTCTCCCTGGAGGACC
AAGTTACAGGAAATCAAGAGCAGCCTGGACAACCACACTGACGTGGTCTTCATCGCTGATTTCC
CTGGGCTGCACCTGGAGAACTTTGTGAGCGAAGACCTGGGCAACACTAGCATCCAGCTGCTGCA
GGGACAGGTGACCGTGGAGCTGGTAGCAGAACAGAAGAACCAGACTCTTCAGGAGGGAGAAAAA
ATGCAGTTGCCTGCGGGTGAGTACCATAAGGTGTATACGCTGCCTCCTGGTCCTTCATGCTATA
TGTACATCTATGTCAACACCACAGAGCTTGCCCTGGAGCAAGACTTGGCATATCTGCAAGAATT
AAAGGAGAAAGTAGAGAATGGAAGTGAAACAGGGCCTCTGCCTCCGGAGCTGCAGCCTCTGCTG
GGCGGGGAAGTAAAAGGGGGCCCCGAGCCAACACCTCTGGTGCAGACCTTTCTCAGACGCCAGC
AAAGGCTCCAGGAGATTGAACGCCGGCGAAACGCCTCCTTTCACGAGCGACTTTTCCGATTCTT
GCTGCGAAAGCTCTATATCTTTCGCCGCAGCTTCCTGATGACTTGTATCTCACTTCGAAATCTG
GTATTAGGCCGCCCTTCCCTGGAGCAGCTGGCCCAAGAGGTGGCTTACGCGAACTTGAGACCCT
TTGAGCCAGTTGAAGAGTCGAGTCCTTCAAACACAGAGTCTTCAAATCCTAATCCTCCTGAGCC
AAATTCGGACCCTGTCCACTCAGAGTTCTGAGGGAGGCCAGATGTTGGGGAGAGATGTAGGAGC
TGCCAGTCACAGGGCCATTACCTATGCAGTGGACATTTGAAAACATTTTCAGATTTTTTAAAAT
ATTTTCTTCCTTATCTATAGCTCTCATAAATTCAGAGAGGACAGTTTAGAGGAACCAAGGAGGT
AAAGCAAAGATAAGATTTATCAAGCCCAGGTTGAGGGGCTTGGGGCAGGGGCTTAAAAAACAAT
GGGAAGGAGTTCCCATCGTGGCTCAGTGGTTAACGAATCCAACTAGGAACCATGAGGTTTCGGG
TTTGATCCTTGGCCTTGCTAAGTGGGTTGGGGATCCGGTGTTGCTGTGAGCTGCGGTGTAGGTT
GCAGACATGGCTTGGATGCTATGTTGCTGTGGCTCTGGCGTAGGCTCGCGTGTACGGCTCTGAT
TGGACCCCTAGCCTGGGAATCTCCATATGCCACAGGTGCAGCCCTAGAAAAGACACACACACAC
ACAAATGTGAAAATGGCTTTCTAGGGTAAAGGAGTAAGAATCAGGTTTAAAGTGACTGGCTCCT
TGGGGAAGGAGATTTAAGGTACCATGAGGAAAATAATAGCAGACTGTTCTCAGTGTTTGCCATG
TGCTGGGCACTGGGTGAAGCGCTGTGCCTGCATTATTACATTTAGTCCTTAATGGCCATTAGTC
CTGTCTTACAGTTGGAGAAACTGAGGCTGAGAGGTAATATAATTTGCTCAAAGATACCCATCTA
GTAAGGAATGGATTGATGGTTGAACCTCGGTCCTGCACCCTGCCTCTTGTAATTTTCAGAATCA
CTGACAATAATTCTGAGATAATGCAGCTTAAACCTTGTCTCCTTACAAAGTATGATTAGGATGG
TGATCAGGTCTTAAAAGCACACAGTAATTTTCTCTTCACTGCAATTTTGTTTCCTTCTTTGTTC
TTAGTATTTATATAGCCAGTATGTTTCTCACTAGCAGTTATGAGCATAGTTAGAATAGTACAAG
GTTCAATAAGGAAATTTAGATGATTAGTAATGGTATTTCTATAAAAATAGGCTTATTATCTAGC
CTTTTGTGAGCAGGAGGTGACGTAAGATTTAACTTAACATGGTGAAAGATTAGGTTTGGATGTT
GAAGGTTTGTATGTGATTCAGGAAGATCCTCAATTCTGTGGAAGTTCAAAGGCCTACACTAGAC
TAGGAAGTGAGAATGCCTAATTACACAAAACAAAACCAGGGGTTTCCATCACGGCTCAGTGGAA
ATGAATCTGACTAGCATCCATGAGGACACAGGTTTGATCCCTGGCCTCGCTCAGTTGGTTAAGG
ATCCGGTGTTGCCGTGAGCTGTGGTGTAAGTCGCAGATGCAGTTCGGATCCTGAGTTGCTGCGG
CTGTGGCTGTGGCTGTGGTGTAGGCCAGCAGCTGTAGCTCTAATTTGACCCCTAGCTTGGGAAC
CTCAATGTGCCACGGGTACGGCCCTAAAAAGACAAAAAACAAAAACAAAATGAGCCCCCTGCTC
TGGGGCCTCATGGTCCCAAGACAGAGACTGGCAGTAGCCTGGCAGTGCCAGTGACTTTGATAAA
GGATTGCATCTCTTTTCAGGCATCTCTTCCCATGCCCCGCCCCACCCAGTCTCAGGGCTCTTTC
CTAGGCAGCTGCCTTTTCACCACATACTTGGGGTGATTTATGTCTGCTCCGTGGTTTCCAGTCA
TGCTGCTGCTTAGGTTTCTGTCCTGTGCCCTAGAGCTGTATGTCCAGCTCCATCTGGATATCCC
ACAGAGCTTTCAAACTGTCCAAACAGAACTTGCATTCCTCAGACCTGCTTCTCCTTTATTAGTG
AATGGTGACTTTTTTCCCACTGGGCCGGGCTGGGGATTGAATCCATGCCTCAGTAGTGAATTGA
GCCGCTGCAGAGACAATGCCAGATCCTTAACTTGCTGTGCCACATTGGGAACTCCAACTTTTTT
ATTTAAACCAATCCCTGAGTAATCAGCCTTGACTCTCCCTTTCTCGCATTCCTTTTTTTTTTTT
TTTTTAAAGAATCTAAACTTTTTTGTCTTTTGGTGTTTTTGTTTTTTTGGCTGTGCCTGTGGCA
CGTGGTAAATTTTCAGGCCAGAGCGTCACACCTACACCTCAGCAGTGACAACACCGGCTAGGCC
ACCAGGGAACACCCTTCTCATTCTTGAGATTTCAAGTCCCATCAATTCTACCTCTGTTGGATCT
GTTGAATTCATCTCTACTACCTCTGTTCTTTCAGCCTTTATACTGGAACCTAGTTAGGGATAGA
CTAGAGCAGGCCTGCCATGTAGTTGGGCAGGTTGGGCCTGAATAAGGGTACCCCAGAGGCCACA
GGGAGCTTGGCAGCAAGTCCTTCTGCTTCATACCAGGCATTTGGTGGGTTAGCAGTGGTTATGT
CATAGGGCATCTCACTAACTGAAAGCCAGCGTGGCAGGCAGTCCTTTGCCAGTAGGTTTGGCTA
TCCTTGTTCCCCCCACAACCCCTGCACCCACATTTTACTAAGAATAGCTCTTCACTTTGGGAGG
GAACTCATGCAAAGGTACTTTTCTAACACAGGCATGGGTGCTGCTTTCCCACAACTGTGAGTAC
CACCTGTCTCCTTATCTAAATGAAAATATTAGGGATGAGGTCAAGATGCTAGTCTTAATAAAGA
AAAGCTGATAATTGGAGTAAATCAAGGTTATTCAAATTTTGGGCATCCCCAGGCTGTGGATCTT
TCGTGTTCTTTTAGCCAGAAGGCCTTGCATCCTGTCCCCAGCATTTGGATCATTTGTCCCTGAT
CAACATTGTGCCCCTTGAAAACCCGAGAAAAGCATGAAGTGCTTTTTTCAGCCATAATCACCTT
CACCCCTTGCTTCTACTCTTCTCCCTGAGCTGGTTAATCCCTATCCCAGGGCTGGTTAGGATAA
ACCCACCATTTAAGGTTACCCTCCATAGGCAGACTGAGCTGGGATCATCCTGGCAAATACTGAA
TTGAACCTCAAAGGCCATTACTTGTCTGGTGCTGCTTCACCAGCCTACGGGCACTTAATCATCC
CCCTCATTTAGCCAACAATGGTTGCTTATCTTTTGACAGTAATGCAATGACATCTAAAAGCTTT
TTGAAACATTCTGGAGCTTCTTAATGTCATGCAAAGTTGAAGTCCTCAAGTTTCAGAGTACGTC
AGTTTTCATTGACTCTTTAAAATTTAACCTTGCCTTTCCTCCCAACCTGTTTCTAAACTTTCAA
GCCTCTAGGCAAACAGGTATAAGCTTTCCTTAGACCACTAGTTTTCATACATGCTGTGAACATA
TGCCAACTGGGTCCTAGGCTCAAGGTTGGTCCAAGCTCTATGGTTAATGAACCTGTTACACCAA
CTGCCACAAATAAGCCCTTGGAATTTGTATTTTCACTAGTTTTAAGTATATCTCATTTTAGCTC
ACTTACTGTGTAAGATACTGAAAACTGGTCCCTCACTGCTGTCTACTGTTTTCAAACTAGTATC
TACTAAAGATCTAACCTGCAGCCTTAAACGCTTATTTATGTAGAGATCAAAACTTAAGGCAATA
AACTCTAAAATTTCTAGAGATGAAAATCTGCTTAAATTTTTGAAAATAAACATCACTGCTTCCA
CATTATACTCAGTGGTTCTTATGCCCTTATTTTCTTTTTTAGGGCCACACCCACAGCATATGAA
GTTCCCAGGCTAGGAGCTTAGGGGCAGAAGCAAACCACAGCTGCCTGCCTAGCCACAGCAAAGC
AGGATCTGTGCCACATCTGCAACTTGCACTGAAGCTCATGGCAACATTGGAACCTTAACCTTAC
CCACCAAGACCAAGGATGGAACCTATGCCCTTAGTTTTAAACACTGCTGACGGTACAATAGTGG
CAGCTGCAAAAGGGGATGAATTTTATCCATTTTGCTGGTGAAGAAAAGGGGCAATGCTGGACAA
ACTGAAACCAAAACTTAAATCTTTTTCTTAATGCTAGAAATAGGATTTACAAACCTTTTAAATG
CCTGCAGTTAGGGTTGAAGTGATTTCTGAGCCATAGGTGGGATTACAATTACTCAGGGTTTCAA
CTCATATTCACGCCAGAACACTTGACAACAATAATGGACACGTTAAGGTAGAACCTAGCATTTT
ATTTAGATCTTCATTAAACTGTTGGAATTGAGAACCAGACATACGTAATAAACCTCCAAAAATA
GATCCTGAAAGGCACTTTCTGCTTAGGGCAAGCAGTCATGGAATAAGCATGTAAACAAGCTGGC
TTCTCTGTACCACACCAGCCAAGTCAGCTTTCTCCATGGCCAGCCGCACCAGCTCTGCCCTCCC
TTCTGTTAACACCAGCCAGAACCCCTGTAGGTCTAACCCAAGGTTTTTCTGTAGGACACCTTGG
CCTACCTGGGAATGCTGGAAACATGTTAAAGGAATCATGGTGTTGAGGAAAAAAAGAAAACTCT
TTTAAAAGCTGCCATCTGAGGTGATGGCTTCTCTGTACTTACGCCATACCCCAGAATACAATAA
ATAAGCAATTAGAAAATGTTCAAGTATGAAGGGATTTCCTCCTCCCCGCCAAAAGCACTGCTCT
CTGAAGGAAGCTGGTTTCTCTGTAGCTACACCAGCTGTTCAGAAAGCTCATTGGACCTGGTTTT
GAAAACAAAACAAAGTTAAAACCCTGGGAGGAATTATTGTGCAGTGTGGAGTACTCAGTCTTTC
TTATAAAGAAAAAAAAAAGTTATCTGGTACCAAAGTGTGCAACCTACAGACCCTCAGGTACTGC
CCTGTGACTTCTCTGTATGATATCACAAGGGTGCCAAGTGCCTGTTTTTCTAGAGCTAGGAGTT
GGTGGTTTGGCTAGTGCTGAAACCATGCATAGGATTGGTTTACTAAATAAAAACCTTATTACGT
ACGTCCTCCAAAAGACAGCTGAAAAGTGGAGAGATTTTGATTTGGTGCTGTTTAAAAGAGATGG
CAATTAAGAGCATAAGCACCAGGGAGATGGTTTAATGGTAACTGCCTTTTTTTTTTCTTTCTTT
CTTATGTCAGGCTAGAGCTCCAAGTGGAACTTGCGTTACATGCAAGAATGACTGGATAGGGAAC
ACTCCCTGACAAAGAGCTACATAATTAGAAATGGATCAAGTTATAGGGAGGGTAAGGGAAGGCT
TCACATTCATAATAGAGCTCAAGACATTACAAATTCATGCTGACAGGGCTGTGGCATTGCCAGA
CAGAGGCTATAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003354792	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000021229
	ENSSSCP00000021229.3
	ENSSSCP00025038399.1
	ENSSSCP00025038696.1
	ENSSSCP00040005221.1
	ENSSSCP00055035776.1
	ENSSSCP00060026352.1
	ENSSSCP00065026648.1
	ENSSSCP00065026662.1
	ENSSSCP00070049542.1
	ENSSSCP00070049543.1
	ENSSSCP00070049544.1

RefSeq Acc Id:

XP_003354792 ⟸ XM_003354744

- UniProtKB:

A0A4X1W535 (UniProtKB/TrEMBL), A0A5G2QEB8 (UniProtKB/TrEMBL), A0A8D1VNN7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGVSARSARAQPHSDKVQKDKSGQTSGPPQSSRMGKLLGFEWTDVSSWGRLVTLLNRPTDPASL
AVFRFLFGLLMVLDIPQERGLSSLDRRYLDGLEVCRFPLLDALQPLPLDWMYLVYTIMFLGALG
MMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFVDANRYWSVDGLLSSRKRN
AHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLVLSEEMTSLLVVH
WCGLLLDLSAGFLLFFDATRSIGLLFVSYFHCMNSQLFSIGMFPYVMLASSPLFCSPGWPRKLV
AHCPKRLQDLLPLRIAPQPSASCMYKRSRARGGQKPGLRHRLGAAFTLLYLLEQLFLPYSHFLT
QGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYLNPGVFTQSRRWKDHADMLKQYA
TCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTPWLQPLLMGLSPW
RTKLQEIKSSLDNHTDVVFIADFPGLHLENFVSEDLGNTSIQLLQGQVTVELVAEQKNQTLQEG
EKMQLPAGEYHKVYTLPPGPSCYMYIYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQP
LLGGEVKGGPEPTPLVQTFLRRQQRLQEIERRRNASFHERLFRFLLRKLYIFRRSFLMTCISLR
NLVLGRPSLEQLAQEVAYANLRPFEPVEESSPSNTESSNPNPPEPNSDPVHSEF

hide sequence

Ensembl Acc Id:

ENSSSCP00000063000 ⟸ ENSSSCT00000089421

Ensembl Acc Id:

ENSSSCP00000021229 ⟸ ENSSSCT00000031020

Ensembl Acc Id:

ENSSSCP00000072334 ⟸ ENSSSCT00000079244

Ensembl Acc Id:

ENSSSCP00000060390 ⟸ ENSSSCT00000080468

Protein Domains

HTTM-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000027381	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025063868	UniProtKB/TrEMBL
	ENSSSCG00040010379	UniProtKB/TrEMBL
	ENSSSCG00055022515	UniProtKB/TrEMBL
	ENSSSCG00060045337	UniProtKB/TrEMBL
	ENSSSCG00065044938	UniProtKB/TrEMBL
	ENSSSCG00070029049	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000031020	ENTREZGENE
	ENSSSCT00000031020.4	UniProtKB/TrEMBL
	ENSSSCT00025088018.1	UniProtKB/TrEMBL
	ENSSSCT00025088562.1	UniProtKB/TrEMBL
	ENSSSCT00040013642.1	UniProtKB/TrEMBL
	ENSSSCT00055044906.1	UniProtKB/TrEMBL
	ENSSSCT00060061532.1	UniProtKB/TrEMBL
	ENSSSCT00065061488.1	UniProtKB/TrEMBL
	ENSSSCT00065061516.1	UniProtKB/TrEMBL
	ENSSSCT00070058269.1	UniProtKB/TrEMBL
	ENSSSCT00070058270.1	UniProtKB/TrEMBL
	ENSSSCT00070058272.1	UniProtKB/TrEMBL
InterPro	HTTM	UniProtKB/TrEMBL
	HTTM_dom	UniProtKB/TrEMBL
	VKG_COase	UniProtKB/TrEMBL
	VKGC_lumenal_dom	UniProtKB/TrEMBL
KEGG Report	ssc:100620337	UniProtKB/TrEMBL
NCBI Gene	GGCX	ENTREZGENE
PANTHER	PTHR12639	UniProtKB/TrEMBL
	VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE	UniProtKB/TrEMBL
Pfam	VKG_Carbox	UniProtKB/TrEMBL
	VKGC_lumenal_dom	UniProtKB/TrEMBL
SMART	HTTM	UniProtKB/TrEMBL
UniProt	A0A4X1W065_PIG	UniProtKB/TrEMBL
	A0A4X1W535	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1W687_PIG	UniProtKB/TrEMBL
	A0A5G2QEB8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1VNN7	ENTREZGENE, UniProtKB/TrEMBL
	I3LB10_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:88435	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB