ONTOLOGY REPORT - ANNOTATIONS
Term: negative regulation of chromosome segregation
Accession: GO:0051985
browse the term
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
Synonyms: exact_synonym: down regulation of chromosome segregation; downregulation of chromosome segregation
narrow_synonym: inhibition of chromosome segregation
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CHTF18
chromosome transmission fidelity factor 18
acts_upstream_of_or_within
ISO
(PMID:23133398)
MGI
PMID:23133398
NCBI chr16:788,620...798,074
Ensembl chr16:788,046...800,737
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MAD1L1
mitotic arrest deficient 1 like 1
involved_in
IDA
(PMID:19010891)
UniProt
PMID:19010891
NCBI chr 7:1,815,795...2,232,945
Ensembl chr 7:1,815,793...2,233,243
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MAD2L1BP
MAD2L1 binding protein
involved_in
IMP
(PMID:18022368)
UniProt
PMID:18022368
NCBI chr 6:43,629,540...43,640,941
Ensembl chr 6:43,629,540...43,640,941
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PRAP1
proline rich acidic protein 1
involved_in
IDA
(PMID:24374861)
UniProt
PMID:24374861
NCBI chr10:133,347,373...133,352,683
Ensembl chr10:133,347,368...133,352,683
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TTK
TTK protein kinase
involved_in acts_upstream_of_or_within
IEA ISO IBA
(PMID:21558374)
Ensembl MGI GO_Central
PMID:21558374
GO_REF:0000033 GO_REF:0000107
NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527
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CHFR
checkpoint with forkhead and ring finger domains
involved_in
IMP
(PMID:10935642)
UniProt
PMID:10935642
NCBI chr12:132,832,356...132,887,618
Ensembl chr12:132,822,187...132,956,304
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APC
APC regulator of WNT signaling pathway
acts_upstream_of_or_within
IMP
(PMID:17227893)
MGI
PMID:17227893
NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239
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ATM
ATM serine/threonine kinase
involved_in
IMP
(PMID:11943150)
UniProt
PMID:11943150
NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,823...108,369,102
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BIRC5
baculoviral IAP repeat containing 5
involved_in
IMP
(PMID:12805209)
UniProt
PMID:12805209
NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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BUB1
BUB1 mitotic checkpoint serine/threonine kinase
involved_in
TAS IEA IBA IMP
(PMID:9790499) (PMID:18995837)
PINC TreeGrafter GO_Central UniProt InterPro
PMID:9790499 PMID:18995837
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 2:110,637,528...110,678,063
Ensembl chr 2:110,637,528...110,678,063
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BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
involved_in
IDA IBA IMP NAS IEA
(PMID:10477750) (PMID:20220147) (PMID:11535616)
UniProt GO_Central ComplexPortal InterPro
PMID:10477750 PMID:11535616 PMID:20220147
GO_REF:0000002 GO_REF:0000033
NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123
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BUB3
BUB3 mitotic checkpoint protein
involved_in
NAS IBA IEA
(PMID:11535616)
ComplexPortal GO_Central TreeGrafter
PMID:11535616
GO_REF:0000033 GO_REF:0000118
NCBI chr10:123,154,402...123,170,467
Ensembl chr10:123,154,402...123,170,467
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CDC20
cell division cycle 20
involved_in
NAS
(PMID:11535616)
ComplexPortal
PMID:11535616
NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
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CENPE
centromere protein E
involved_in
ISO
(MGI:2673075|PMID:12925705)
UniProt
PMID:12925705
MGI:2673075
NCBI chr 4:103,105,811...103,198,343
Ensembl chr 4:103,105,349...103,198,445
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CENPF
centromere protein F
involved_in
NAS
(PMID:12974617)
UniProt
PMID:12974617
NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574
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HASPIN
histone H3 associated protein kinase
involved_in
IMP
(PMID:23071153)
UniProt
PMID:23071153
NCBI chr17:3,723,903...3,726,699
Ensembl chr17:3,723,903...3,726,699
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IK
IK cytokine
involved_in
IMP
(PMID:22351768)
UniProt
PMID:22351768
NCBI chr 5:140,647,829...140,662,480
Ensembl chr 5:140,647,058...140,662,480
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KHDC3L
KH domain containing 3 like, subcortical maternal complex member
acts_upstream_of_or_within
ISO
(PMID:19376971)
MGI
PMID:19376971
NCBI chr 6:73,362,658...73,364,171
Ensembl chr 6:73,362,658...73,364,171
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KLHL22
kelch like family member 22
involved_in
IMP
(PMID:23455478)
UniProt
PMID:23455478
NCBI chr22:20,441,519...20,495,795
Ensembl chr22:20,441,519...20,495,844
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KNTC1
kinetochore associated 1
involved_in
IDA IBA
(PMID:11146660)
UniProt GO_Central
PMID:11146660
GO_REF:0000033
NCBI chr12:122,527,249...122,626,396
Ensembl chr12:122,527,246...122,626,396
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MAD1L1
mitotic arrest deficient 1 like 1
involved_in
NAS IEA IBA IMP IDA
(PMID:9546394) (PMID:36322655), (PMID:9546394) (PMID:18981471)
UniProt TreeGrafter GO_Central InterPro
PMID:9546394 PMID:18981471 PMID:36322655
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 7:1,815,795...2,232,945
Ensembl chr 7:1,815,793...2,233,243
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MAD2L1
mitotic arrest deficient 2 like 1
involved_in acts_upstream_of_or_within
IDA ISO IBA NAS IEA
(PMID:18981471) (PMID:11201745) (PMID:11535616)
UniProt MGI GO_Central ComplexPortal Ensembl
PMID:11201745 PMID:11535616 PMID:18981471
GO_REF:0000033 GO_REF:0000107
NCBI chr 4:120,055,623...120,066,848
Ensembl chr 4:120,055,623...120,066,858
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MAD2L2
mitotic arrest deficient 2 like 2
involved_in
TAS
(PMID:10366450)
PINC
PMID:10366450
NCBI chr 1:11,674,480...11,691,830
Ensembl chr 1:11,658,918...11,691,811
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MNAT1
MNAT1 component of CDK activating kinase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr14:60,734,761...60,969,965
Ensembl chr14:60,734,742...60,969,965
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NDC80
NDC80 kinetochore complex component
involved_in
NAS
(PMID:18455984)
ComplexPortal
PMID:18455984
NCBI chr18:2,571,557...2,616,635
Ensembl chr18:2,571,557...2,616,635
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NUF2
NUF2 component of NDC80 kinetochore complex
involved_in
NAS
(PMID:18455984)
ComplexPortal
PMID:18455984
NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764
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PLK1
polo like kinase 1
involved_in
IMP
(PMID:23455478)
UniProt
PMID:23455478
NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367
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PSMG2
proteasome assembly chaperone 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12147697)
Ensembl MGI
PMID:12147697
GO_REF:0000107
NCBI chr18:12,658,738...12,725,740
Ensembl chr18:12,658,043...12,728,945
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SPC24
SPC24 component of NDC80 kinetochore complex
involved_in
NAS
(PMID:18455984)
ComplexPortal
PMID:18455984
NCBI chr19:11,145,493...11,155,782
Ensembl chr19:11,131,520...11,155,807
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SPC25
SPC25 component of NDC80 kinetochore complex
involved_in
NAS
(PMID:18455984)
ComplexPortal
PMID:18455984
NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371
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SPDL1
spindle apparatus coiled-coil protein 1
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 5:169,583,773...169,604,778
Ensembl chr 5:169,583,636...169,604,778
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TEX14
testis expressed 14, intercellular bridge forming factor
involved_in
ISS IBA IEA
UniProt GO_Central InterPro Ensembl
GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr17:58,556,678...58,692,045
Ensembl chr17:58,556,678...58,692,055
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TPR
translocated promoter region, nuclear basket protein
involved_in
IMP
(PMID:20133940)
UniProt
PMID:20133940
NCBI chr 1:186,311,652...186,375,253
Ensembl chr 1:186,311,652...186,375,693
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TRIP13
thyroid hormone receptor interactor 13
involved_in
IMP
(PMID:28553959)
UniProt
PMID:28553959
NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357
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TTK
TTK protein kinase
involved_in
TAS IBA IEA
(PMID:10366450)
PINC GO_Central Ensembl
PMID:10366450
GO_REF:0000033 GO_REF:0000107
NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527
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ZNF207
zinc finger protein 207
involved_in
IMP IEA IBA
(PMID:24462186), (PMID:24462187)
UniProt TreeGrafter GO_Central
PMID:24462186 PMID:24462187
GO_REF:0000033 GO_REF:0000118
NCBI chr17:32,350,157...32,381,885
Ensembl chr17:32,350,132...32,381,885
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ZW10
zw10 kinetochore protein
involved_in
IDA IBA IEA IMP
(PMID:11146660) (PMID:15824131)
UniProt GO_Central TreeGrafter
PMID:11146660 PMID:15824131
GO_REF:0000033 GO_REF:0000118
NCBI chr11:113,733,187...113,773,692
Ensembl chr11:113,733,187...113,773,735
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ZWILCH
zwilch kinetochore protein
involved_in
IMP IBA IEA
(PMID:15824131)
UniProt GO_Central TreeGrafter
PMID:15824131
GO_REF:0000033 GO_REF:0000104 GO_REF:0000118
NCBI chr15:66,505,326...66,550,130
Ensembl chr15:66,504,959...66,550,130
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ZWINT
ZW10 interacting kinetochore protein
involved_in
IDA IBA
(PMID:15485811)
HGNC-UCL GO_Central
PMID:15485811
GO_REF:0000033
NCBI chr10:56,357,227...56,361,273
Ensembl chr10:56,357,227...56,361,273
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SIRT1
sirtuin 1
involved_in
IDA
(PMID:30409912)
UniProt
PMID:30409912
NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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MOS
MOS proto-oncogene, serine/threonine kinase
involved_in
IEA IBA ISS
Ensembl GO_Central UniProt
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 8:56,112,942...56,113,982
Ensembl chr 8:56,112,942...56,113,982
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FBXO5
F-box protein 5
involved_in
IDA
(PMID:11988738), (PMID:16921029)
UniProt
PMID:11988738 PMID:16921029
NCBI chr 6:152,970,535...152,983,579
Ensembl chr 6:152,970,519...152,983,579
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RAD21
RAD21 cohesin complex component
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 8:116,845,934...116,874,776
Ensembl chr 8:116,845,934...116,874,776
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USP44
ubiquitin specific peptidase 44
involved_in
IDA
(PMID:17443180)
UniProt
PMID:17443180
NCBI chr12:95,516,560...95,551,681
Ensembl chr12:95,516,560...95,551,476
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KNL1
kinetochore scaffold 1
involved_in
ISS
UniProt
GO_REF:0000024
NCBI chr15:40,594,249...40,664,342
Ensembl chr15:40,594,020...40,664,342
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AURKB
aurora kinase B
involved_in
NAS
(PMID:17956729)
ComplexPortal
PMID:17956729
NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600
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BIRC5
baculoviral IAP repeat containing 5
involved_in
NAS
(PMID:17956729)
ComplexPortal
PMID:17956729
NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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CDCA8
cell division cycle associated 8
involved_in
NAS
(PMID:17956729)
ComplexPortal
PMID:17956729
NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719
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DYNC1LI1
dynein cytoplasmic 1 light intermediate chain 1
involved_in
IMP
(PMID:19229290)
UniProt
PMID:19229290
NCBI chr 3:32,525,974...32,570,858
Ensembl chr 3:32,525,974...32,570,858
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GEN1
GEN1 Holliday junction 5' flap endonuclease
involved_in
IMP
(PMID:23108668)
UniProt
PMID:23108668
NCBI chr 2:17,753,278...17,788,946
Ensembl chr 2:17,753,858...17,788,946
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INCENP
inner centromere protein
involved_in
NAS
(PMID:17956729)
ComplexPortal
PMID:17956729
NCBI chr11:62,124,011...62,153,169
Ensembl chr11:62,123,998...62,153,169
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MAD1L1
mitotic arrest deficient 1 like 1
involved_in
IDA IMP
(PMID:22898774) (PMID:36322655)
ComplexPortal UniProt
PMID:22898774 PMID:36322655
NCBI chr 7:1,815,795...2,232,945
Ensembl chr 7:1,815,793...2,233,243
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MAD2L1
mitotic arrest deficient 2 like 1
involved_in
IDA IMP IEA
(PMID:22898774), (PMID:8824189) (PMID:20870947)
UniProt Ensembl
PMID:8824189 PMID:20870947 PMID:22898774
GO_REF:0000107
NCBI chr 4:120,055,623...120,066,848
Ensembl chr 4:120,055,623...120,066,858
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NDC80
NDC80 kinetochore complex component
involved_in
IMP
(PMID:25743205)
UniProt
PMID:25743205
NCBI chr18:2,571,557...2,616,635
Ensembl chr18:2,571,557...2,616,635
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PCID2
PCI domain containing 2
involved_in
IEA IMP
(PMID:20870947)
Ensembl UniProt
PMID:20870947
GO_REF:0000107
NCBI chr13:113,165,002...113,208,669
Ensembl chr13:113,177,536...113,208,715
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TPR
translocated promoter region, nuclear basket protein
involved_in
IMP
(PMID:18981471), (PMID:19273613)
UniProt
PMID:18981471 PMID:19273613
NCBI chr 1:186,311,652...186,375,253
Ensembl chr 1:186,311,652...186,375,693
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XRCC3
X-ray repair cross complementing 3
involved_in
IMP
(PMID:23108668)
UniProt
PMID:23108668
NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504
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ZWINT
ZW10 interacting kinetochore protein
involved_in
IEA ISS
Ensembl UniProt
GO_REF:0000024 GO_REF:0000107
NCBI chr10:56,357,227...56,361,273
Ensembl chr10:56,357,227...56,361,273
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ANAPC15
anaphase promoting complex subunit 15
involved_in
IEA IBA IMP
(PMID:21926987)
InterPro GO_Central UniProt
PMID:21926987
GO_REF:0000002 GO_REF:0000033
NCBI chr11:72,106,372...72,112,780
Ensembl chr11:72,106,378...72,112,780
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CCNB1
cyclin B1
involved_in
IMP
(PMID:18195732)
BHF-UCL
PMID:18195732
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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CDK5RAP2
CDK5 regulatory subunit associated protein 2
involved_in
IDA IBA IEA
(PMID:19282672)
UniProt GO_Central TreeGrafter
PMID:19282672
GO_REF:0000033 GO_REF:0000118
NCBI chr 9:120,388,875...120,580,167
Ensembl chr 9:120,388,875...120,580,170
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DUSP1
dual specificity phosphatase 1
involved_in
ISS
UniProt
GO_REF:0000024
NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
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KNL1
kinetochore scaffold 1
involved_in
IMP
(PMID:19893618)
UniProt
PMID:19893618
NCBI chr15:40,594,249...40,664,342
Ensembl chr15:40,594,020...40,664,342
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LCMT1
leucine carboxyl methyltransferase 1
acts_upstream_of_or_within
IMP
(PMID:17724024)
MGI
PMID:17724024
NCBI chr16:25,111,742...25,178,228
Ensembl chr16:25,111,731...25,178,231
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PDE4DIP
phosphodiesterase 4D interacting protein
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 1:148,808,434...149,033,016
Ensembl chr 1:148,808,140...149,048,286
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PRP4K
pre-mRNA processing factor kinase PRP4K
involved_in
IDA
(PMID:17998396)
UniProt
PMID:17998396
NCBI chr 6:4,021,300...4,064,983
Ensembl chr 6:4,021,267...4,064,983
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USP44
ubiquitin specific peptidase 44
involved_in
IEA ISS
Ensembl UniProt
GO_REF:0000024 GO_REF:0000107
NCBI chr12:95,516,560...95,551,681
Ensembl chr12:95,516,560...95,551,476
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