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Gene: FBXO5 (F-box protein 5) Homo sapiens
Symbol: FBXO5
Name: F-box protein 5
Description: Exhibits anaphase-promoting complex binding activity; protein kinase binding activity; and ubiquitin ligase inhibitor activity. Involved in several processes, including positive regulation of mesenchymal stem cell migration; regulation of cell cycle process; and regulation of cellular response to stress. Localizes to the cytoplasm; nucleoplasm; and spindle.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: early mitotic inhibitor 1; EMI1; F-box only protein 5; F-box protein Fbx5; FBX5; Fbxo31
Mus musculus (house mouse) : Fbxo5 (F-box protein 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxo5 (F-box protein 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo5 (F-box protein 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO5 (F-box protein 5)
Canis lupus familiaris (dog) : FBXO5 (F-box protein 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo5 (F-box protein 5)
Sus scrofa (pig) : FBXO5 (F-box protein 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6152,970,519 - 152,983,579 (-)Ensembl
GRCh386152,970,535 - 152,983,579 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376153,291,658 - 153,304,740 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366153,333,351 - 153,345,867 (-)NCBINCBI36hg18NCBI36
Build 346153,383,773 - 153,396,288NCBI
Celera6154,025,328 - 154,038,410 (-)NCBI
Cytogenetic Map6q25.2NCBI
HuRef6150,854,447 - 150,867,531 (-)NCBIHuRef
CHM1_16153,555,576 - 153,568,660 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FBXO5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319734
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.