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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet formation
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Accession:GO:0030220 term browser browse the term
Definition:The process in which platelets bud from long processes extended by megakaryocytes.
Synonyms:exact_synonym: platelet extrusion



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platelet formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 involved_in ISO
IEA
(PMID:23434115)
GO_REF:0000107
RGD
Ensembl
PMID:23434115 GO_REF:0000107 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5314162|PMID:22128142)
UniProt
RGD
PMID:22128142 GO_REF:0000024 MGI:5314162 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423
JBrowse link
G Clec1b C-type lectin domain family 1, member B acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1889810 (MGI:5512895|PMID:23112346)
PMID:21873635
RGD PMID:23112346 PMID:21873635 MGI:5512895, RGD:13792537 NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291
JBrowse link
G Ep300 E1A binding protein p300 acts_upstream_of_or_within ISO MGI:3813243|MGI:97076 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Gata1 GATA binding protein 1 involved_in
acts_upstream_of_or_within
ISO (PMID:10700180), (PMID:11675338), (PMID:12483298)
MGI:2177587 (MGI:894135|PMID:9233806)
RGD PMID:9233806 PMID:10700180 PMID:11675338 PMID:12483298 MGI:894135 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(MGI:3844189|PMID:19211936)
UniProt
RGD
PMID:19211936 GO_REF:0000024 MGI:3844189 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mfap2 microfibril associated protein 2 acts_upstream_of_or_within ISO MGI:3790750 (MGI:3785344|PMID:18281502) RGD PMID:18281502 MGI:3785344 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
JBrowse link
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
GO_REF:0000024
MGI:1913287|MGI:2675830|MGI:96055|MGI:99511 (MGI:5494903|PMID:23509158), (MGI:5512895|PMID:23112346)
PMID:21873635
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23112346 PMID:23509158 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5494903 MGI:5512895, RGD:13792537 NCBI chr20:3,757,396...3,761,024
Ensembl chr20:3,757,536...3,760,735
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor acts_upstream_of_or_within ISO MGI:1276116 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO
ISS
(PMID:12237319)
GO_REF:0000024
RGD
UniProt
PMID:12237319 GO_REF:0000024 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Nbeal2 neurobeachin-like 2 involved_in ISO (PMID:21765411) RGD PMID:21765411 NCBI chr 8:110,603,220...110,633,612
Ensembl chr 8:110,599,389...110,633,707
JBrowse link
G Ppbp pro-platelet basic protein TAS RGD PMID:11785982 RGD:70252 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:2146995|MGI:96055 (MGI:5494903|PMID:23509158) RGD PMID:23509158 MGI:5494903 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2146995|MGI:99511 (MGI:5494903|PMID:23509158)
Ensembl
RGD
PMID:23509158 GO_REF:0000107 MGI:5494903 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2176073|MGI:3046779|MGI:3522206|MGI:3764698 (MGI:4834086|PMID:20525922), (MGI:4848276|PMID:20709909) RGD PMID:20525922 PMID:20709909 MGI:4834086 MGI:4848276 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO MGI:1858004|MGI:2450743 (MGI:3808106|PMID:16763211) RGD PMID:16763211 MGI:3808106 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
JBrowse link
G Tubb1 tubulin, beta 1 class VI involved_in ISO (MGI:6459632|PMID:30446499) RGD PMID:30446499 MGI:6459632 NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856687 (MGI:2450053|PMID:12538872)
Ensembl
RGD
PMID:12538872 GO_REF:0000107 MGI:2450053 NCBI chr12:33,024,596...33,051,399
Ensembl chr12:33,024,650...33,051,393
JBrowse link
G Wdr1 WD repeat domain 1 involved_in ISO (MGI:3784948|PMID:17515402) RGD PMID:17515402 MGI:3784948 NCBI chr14:72,258,032...72,291,768
Ensembl chr14:72,257,956...72,291,766
JBrowse link
G Zfp385a zinc finger protein 385A acts_upstream_of_or_within ISO MGI:3510440 (MGI:3505817|PMID:11927637) RGD PMID:11927637 MGI:3505817 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO UniProtKB:P15976 (PMID:11675338) RGD PMID:11675338 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
JBrowse link
negative regulation of platelet formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:18434589 RGD:151665814 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
positive regulation of platelet formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpl MPL proto-oncogene, thrombopoietin receptor IMP RGD PMID:10606160 RGD:10449003 NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (MGI:6414739|PMID:32103174) RGD PMID:32103174 MGI:6414739 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19874
    developmental process 7013
      anatomical structure formation involved in morphogenesis 1347
        platelet formation 23
          negative regulation of platelet formation 1
          positive regulation of platelet formation 2
          regulation of platelet formation + 3
Path 2
Term Annotations click to browse term
  biological_process 19874
    cellular process 18551
      cellular developmental process 4629
        cell differentiation 4605
          cell development 3187
            hemopoiesis 1039
              myeloid cell differentiation 481
                platelet formation 23
                  negative regulation of platelet formation 1
                  positive regulation of platelet formation 2
                  regulation of platelet formation + 3
paths to the root