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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet formation
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Accession:GO:0030220 term browser browse the term
Definition:The process in which platelets bud from long processes extended by megakaryocytes.
Synonyms:exact_synonym: platelet extrusion



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platelet formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 involved_in ISO
IEA
(PMID:23434115)
GO_REF:0000107
RGD
Ensembl
PMID:23434115 GO_REF:0000107 NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:22128142)
UniProt
RGD
PMID:22128142 GO_REF:0000024 NCBI chr 1:143,587,591...143,593,153
Ensembl chr 1:134,178,331...134,213,423
JBrowse link
G Clec1b C-type lectin domain family 1, member B involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
MGI:1889810 (PMID:23112346)
GO_Central
Ensembl
RGD
PMID:23112346 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291
JBrowse link
G Ep300 E1A binding protein p300 acts_upstream_of_or_within ISO MGI:3813243|MGI:97076 (PMID:18684867) RGD PMID:18684867 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Gata1 GATA binding protein 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:10700180), (PMID:11675338), (PMID:12483298)
GO_REF:0000107
MGI:2177587 (PMID:9233806)
RGD
Ensembl
PMID:9233806 PMID:10700180 PMID:11675338 PMID:12483298 GO_REF:0000107 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(PMID:19211936)
UniProt
RGD
PMID:19211936 GO_REF:0000024 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mfap2 microfibril associated protein 2 acts_upstream_of_or_within ISO MGI:3790750 (PMID:18281502) RGD PMID:18281502 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
JBrowse link
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000107
MGI:1913287|MGI:2675830|MGI:96055|MGI:99511 (PMID:23112346), (PMID:23509158)
GO_REF:0000033
UniProt
Ensembl
RGD
GO_Central
PMID:23112346 PMID:23509158 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,761,832...3,765,679
Ensembl chr20:3,757,536...3,760,735
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor acts_upstream_of_or_within ISO MGI:1276116 (PMID:18684867) RGD PMID:18684867 NCBI chr 5:137,259,288...137,281,540
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO
ISS
(PMID:12237319)
GO_REF:0000024
RGD
UniProt
PMID:12237319 GO_REF:0000024 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Nbeal2 neurobeachin-like 2 involved_in ISO
IEA
(PMID:21765411)
GO_REF:0000107
RGD
Ensembl
PMID:21765411 GO_REF:0000107 NCBI chr 8:110,603,220...110,633,612
Ensembl chr 8:110,599,389...110,633,707
JBrowse link
G Ppbp pro-platelet basic protein TAS RGD PMID:11785982 RGD:70252 NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO
IEA
MGI:2146995|MGI:96055 (PMID:23509158)
GO_REF:0000107
RGD
Ensembl
PMID:23509158 GO_REF:0000107 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of_or_within ISO
IEA
MGI:2146995|MGI:99511 (PMID:23509158)
GO_REF:0000107
RGD
Ensembl
PMID:23509158 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO
IEA
(PMID:30591527)
GO_REF:0000107
RGD
Ensembl
PMID:30591527 GO_REF:0000107 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO
IEA
MGI:2176073|MGI:3046779|MGI:3522206|MGI:3764698 (PMID:20525922), (PMID:20709909)
GO_REF:0000107
RGD
Ensembl
PMID:20525922 PMID:20709909 GO_REF:0000107 NCBI chr 9:21,924,050...21,933,338
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO
IEA
MGI:1858004|MGI:2450743 (PMID:16763211)
GO_REF:0000107
RGD
Ensembl
PMID:16763211 GO_REF:0000107 NCBI chr 5:133,823,093...133,837,737
Ensembl chr 5:128,587,701...128,600,976
JBrowse link
G Tpm4 tropomyosin 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:28134622)
(PMID:28134622), (PMID:35170221)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:28134622 PMID:35170221 GO_REF:0000024 GO_REF:0000107 NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Tubb1 tubulin, beta 1 class VI involved_in ISO
IEA
(PMID:30446499)
GO_REF:0000107
RGD
Ensembl
PMID:30446499 GO_REF:0000107 NCBI chr 3:183,666,189...183,675,656
Ensembl chr 3:163,247,967...163,256,063
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes acts_upstream_of_or_within ISO
IEA
MGI:1856687 (PMID:12538872)
GO_REF:0000107
RGD
Ensembl
PMID:12538872 GO_REF:0000107 NCBI chr12:38,685,484...38,710,668
Ensembl chr12:33,024,650...33,051,393
JBrowse link
G Wdr1 WD repeat domain 1 involved_in ISO
IEA
(PMID:17515402)
GO_REF:0000107
RGD
Ensembl
PMID:17515402 GO_REF:0000107 NCBI chr14:76,470,238...76,504,086
Ensembl chr14:72,257,956...72,291,766
JBrowse link
G Zfp385a zinc finger protein 385A acts_upstream_of_or_within ISO
IEA
MGI:3510440 (PMID:11927637)
GO_REF:0000107
RGD
Ensembl
PMID:11927637 GO_REF:0000107 NCBI chr 7:136,327,393...136,354,017
Ensembl chr 7:134,448,921...134,475,548
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO
IEA
UniProtKB:P15976 (PMID:11675338)
GO_REF:0000107
RGD
Ensembl
PMID:11675338 GO_REF:0000107 NCBI chr19:67,242,922...67,299,149
Ensembl chr19:50,334,682...50,390,591
JBrowse link
negative regulation of platelet formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:18434589 RGD:151665814 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415
JBrowse link
positive regulation of platelet formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpl MPL proto-oncogene, thrombopoietin receptor IMP RGD PMID:10606160 RGD:10449003 NCBI chr 5:137,259,288...137,281,540
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO
IEA
(PMID:32103174)
GO_REF:0000107
RGD
Ensembl
PMID:32103174 GO_REF:0000107 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      anatomical structure formation involved in morphogenesis 1381
        platelet formation 25
          negative regulation of platelet formation 1
          positive regulation of platelet formation 2
          regulation of platelet formation + 3
Path 2
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      cellular developmental process 4833
        cell differentiation 4832
          cell development 3350
            hemopoiesis 1083
              myeloid cell differentiation 516
                platelet formation 25
                  negative regulation of platelet formation 1
                  positive regulation of platelet formation 2
                  regulation of platelet formation + 3
paths to the root