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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet formation
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Accession:GO:0030220 term browser browse the term
Definition:The process in which platelets bud from long processes extended by megakaryocytes.
Synonyms:exact_synonym: platelet extrusion



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platelet formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 involved_in ISO
IEA
(PMID:23434115)
GO_REF:0000107
RGD
Ensembl
PMID:23434115 GO_REF:0000107 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5314162|PMID:22128142)
UniProt
RGD
PMID:22128142 GO_REF:0000024 MGI:5314162 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423
JBrowse link
G Clec1b C-type lectin domain family 1, member B acts_upstream_of_or_within ISO MGI:1889810 (MGI:5512895|PMID:23112346) RGD PMID:23112346 MGI:5512895 NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291
JBrowse link
G Ep300 E1A binding protein p300 acts_upstream_of_or_within ISO MGI:3813243|MGI:97076 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Gata1 GATA binding protein 1 involved_in
acts_upstream_of_or_within
ISO (PMID:10700180), (PMID:11675338), (PMID:12483298)
MGI:2177587 (MGI:894135|PMID:9233806)
RGD PMID:9233806 PMID:10700180 PMID:11675338 PMID:12483298 MGI:894135 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(MGI:3844189|PMID:19211936)
UniProt
RGD
PMID:19211936 GO_REF:0000024 MGI:3844189 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mfap2 microfibril associated protein 2 acts_upstream_of_or_within ISO MGI:3790750 (MGI:3785344|PMID:18281502) RGD PMID:18281502 MGI:3785344 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
JBrowse link
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
GO_REF:0000024
MGI:1913287|MGI:2675830|MGI:96055|MGI:99511 (MGI:5494903|PMID:23509158), (MGI:5512895|PMID:23112346)
PMID:21873635
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23112346 PMID:23509158 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5494903 MGI:5512895, RGD:13792537 NCBI chr20:3,757,396...3,761,024
Ensembl chr20:3,757,536...3,760,735
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor acts_upstream_of_or_within ISO MGI:1276116 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO
ISS
(PMID:12237319)
GO_REF:0000024
RGD
UniProt
PMID:12237319 GO_REF:0000024 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Nbeal2 neurobeachin-like 2 involved_in ISO (PMID:21765411) RGD PMID:21765411 NCBI chr 8:110,603,220...110,633,612
Ensembl chr 8:110,599,389...110,633,707
JBrowse link
G Ppbp pro-platelet basic protein TAS RGD PMID:11785982 RGD:70252 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:2146995|MGI:96055 (MGI:5494903|PMID:23509158) RGD PMID:23509158 MGI:5494903 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2146995|MGI:99511 (MGI:5494903|PMID:23509158)
Ensembl
RGD
PMID:23509158 GO_REF:0000107 MGI:5494903 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2176073|MGI:3046779|MGI:3522206|MGI:3764698 (MGI:4834086|PMID:20525922), (MGI:4848276|PMID:20709909) RGD PMID:20525922 PMID:20709909 MGI:4834086 MGI:4848276 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO MGI:1858004|MGI:2450743 (MGI:3808106|PMID:16763211) RGD PMID:16763211 MGI:3808106 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856687 (MGI:2450053|PMID:12538872)
Ensembl
RGD
PMID:12538872 GO_REF:0000107 MGI:2450053 NCBI chr12:33,024,596...33,051,399
Ensembl chr12:33,024,650...33,051,393
JBrowse link
G Wdr1 WD repeat domain 1 involved_in ISO (MGI:3784948|PMID:17515402) RGD PMID:17515402 MGI:3784948 NCBI chr14:72,258,032...72,291,768
Ensembl chr14:72,257,956...72,291,766
JBrowse link
G Zfp385a zinc finger protein 385A acts_upstream_of_or_within ISO MGI:3510440 (MGI:3505817|PMID:11927637) RGD PMID:11927637 MGI:3505817 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO UniProtKB:P15976 (PMID:11675338) RGD PMID:11675338 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
JBrowse link
positive regulation of platelet formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpl MPL proto-oncogene, thrombopoietin receptor IMP RGD PMID:10606160 RGD:10449003 NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (MGI:6414739|PMID:32103174) RGD PMID:32103174 MGI:6414739 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    developmental process 6920
      anatomical structure formation involved in morphogenesis 1243
        platelet formation 21
          negative regulation of platelet formation 0
          positive regulation of platelet formation 2
          regulation of platelet formation + 2
Path 2
Term Annotations click to browse term
  biological_process 19541
    developmental process 6920
      anatomical structure development 6337
        multicellular organism development 5765
          system development 5408
            immune system development 1108
              hematopoietic or lymphoid organ development 1041
                hemopoiesis 989
                  myeloid cell differentiation 444
                    platelet formation 21
                      negative regulation of platelet formation 0
                      positive regulation of platelet formation 2
                      regulation of platelet formation + 2
paths to the root