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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear replication fork
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Accession:GO:0043596 term browser browse the term
Definition:The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.


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nuclear replication fork term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz1b bromodomain adjacent to zinc finger domain, 1B located_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:135,214,094...135,274,985
Ensembl chr 5:135,216,118...135,274,983 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 is_active_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:21,458,163...21,500,763
Ensembl chr 9:21,458,190...21,503,919 		JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 located_in NAS (MGI:6870982|PMID:18413719) ComplexPortal PMID:18413719 MGI:6870982 NCBI chr11:94,535,798...94,544,611
Ensembl chr11:94,535,822...94,544,790 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 located_in NAS (MGI:6870004|PMID:17289582) ComplexPortal PMID:17289582 MGI:6870004 NCBI chr17:25,111,126...25,114,061
Ensembl chr17:25,107,460...25,114,061 		JBrowse link
G Etaa1 Ewing tumor-associated antigen 1 located_in
is_active_in		 ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:17,888,753...17,903,875
Ensembl chr11:17,888,756...17,903,875 		JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:4,995,535...5,017,602
Ensembl chr 2:4,994,525...5,017,602 		JBrowse link
G Mms22l MMS22-like, DNA repair protein located_in
is_active_in		 ISO
IBA		 (PMID:21055983), (PMID:21055984) UniProt
GO_Central
MGI		 PMID:21055983 PMID:21055984 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:24,496,451...24,602,950
Ensembl chr 4:24,496,451...24,602,950 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit located_in NAS (MGI:6870004|PMID:17289582), (MGI:6870982|PMID:18413719) ComplexPortal PMID:17289582 PMID:18413719 MGI:6870004 MGI:6870982 NCBI chr19:5,532,589...5,538,461
Ensembl chr19:5,532,373...5,538,430 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 is_active_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pcna proliferating cell nuclear antigen located_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 located_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:81,426,572...81,466,088
Ensembl chr 8:81,425,136...81,466,126 		JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 located_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:65,019,577...65,093,045
Ensembl chr 6:65,019,567...65,093,045 		JBrowse link
G Smarcal1 SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 1:72,575,593...72,675,949
Ensembl chr 1:72,622,410...72,672,293 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein located_in
is_active_in		 ISO
IBA		 (PMID:21055983), (PMID:21055984) UniProt
GO_Central
MGI		 PMID:21055983 PMID:21055984 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr15:76,510,437...76,524,129
Ensembl chr15:76,510,202...76,524,158 		JBrowse link
G Trex1 three prime repair exonuclease 1 located_in IDA (PMID:18045533) MGI PMID:18045533 NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802 		JBrowse link
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr14:47,478,401...47,514,352
Ensembl chr14:47,478,401...47,514,314 		JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 located_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:6,339,063...6,356,158
Ensembl chr11:6,339,074...6,356,158 		JBrowse link
G Zranb3 zinc finger, RAN-binding domain containing 3 located_in
is_active_in		 ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:127,881,916...128,030,799
Ensembl chr 1:127,881,921...128,030,784 		JBrowse link
alpha DNA polymerase:primase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 polymerase (DNA directed), alpha 1 located_in
part_of		 ISO
IPI
IBA
IDA		 (PMID:26975377)
(MGI:3687659|PMID:10523676)
(MGI:6478526|PMID:8026492), (PMID:9584195)		 RGD
ComplexPortal
ComplexPortal
GO_Central
MGI		 PMID:7670930 PMID:8026492 PMID:9584195 PMID:10523676 PMID:26975377 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:3687659 MGI:4417868 MGI:4834177 MGI:6478526 RGD:1580605 NCBI chr  X:92,348,372...92,675,993
Ensembl chr  X:92,348,373...92,675,761 		JBrowse link
G Pola2 polymerase (DNA directed), alpha 2 part_of
located_in		 IBA
ISO
IPI
IDA		 (PMID:26975377)
(MGI:3687659|PMID:10523676)
(MGI:6478526|PMID:8026492), (PMID:9584195)		 GO_Central
ComplexPortal
MGI
ComplexPortal		 PMID:8026492 PMID:9584195 PMID:10523676 PMID:26975377 GO_REF:0000033 GO_REF:0000119 MGI:3687659 MGI:4834177 MGI:6478526 NCBI chr19:5,990,574...6,014,266
Ensembl chr19:5,990,570...6,014,230 		JBrowse link
G Prim1 DNA primase, p49 subunit part_of
located_in		 IDA
ISO
IPI
IBA		 (MGI:6478526|PMID:8026492)
(PMID:26975377)
(MGI:3687659|PMID:10523676)		 UniProt
ComplexPortal
ComplexPortal
GO_Central
MGI		 PMID:8026492 PMID:10523676 PMID:26975377 GO_REF:0000033 GO_REF:0000119 MGI:3687659 MGI:4834177 MGI:6478526 NCBI chr10:127,851,084...127,865,899
Ensembl chr10:127,851,041...127,865,906 		JBrowse link
G Prim2 DNA primase, p58 subunit part_of
located_in		 IDA
ISO
IBA
IPI		 (MGI:6478526|PMID:8026492)
(PMID:26975377)
(MGI:3687659|PMID:10523676)		 UniProt
ComplexPortal
GO_Central
ComplexPortal
MGI		 PMID:8026492 PMID:10523676 PMID:26975377 GO_REF:0000033 GO_REF:0000119 MGI:3687659 MGI:4834177 MGI:6478526 NCBI chr 1:33,492,889...33,708,867
Ensembl chr 1:33,492,891...33,708,876 		JBrowse link
delta DNA polymerase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pold1 polymerase (DNA directed), delta 1, catalytic subunit part_of
located_in		 IDA
ISO
IBA		 (MGI:6383350|PMID:11595739)
(PMID:12403614)		 UniProt
RGD
MGI
GO_Central
ComplexPortal		 PMID:10541966 PMID:11595739 PMID:12403614 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 MGI:6383350 RGD:729526 NCBI chr 7:44,182,168...44,198,239
Ensembl chr 7:44,182,170...44,198,273 		JBrowse link
G Pold2 polymerase (DNA directed), delta 2, regulatory subunit part_of
located_in		 IDA
ISO
IBA		 (MGI:6383350|PMID:11595739)
(PMID:12403614)		 UniProt
RGD
MGI
GO_Central
ComplexPortal		 PMID:10541966 PMID:11595739 PMID:12403614 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 MGI:6383350 RGD:729526 NCBI chr11:5,822,180...5,828,256
Ensembl chr11:5,822,180...5,828,292 		JBrowse link
G Pold3 polymerase (DNA-directed), delta 3, accessory subunit part_of
located_in		 IDA
IBA
ISO		 (MGI:6383350|PMID:11595739)
(PMID:12403614)		 UniProt
GO_Central
MGI
ComplexPortal		 PMID:11595739 PMID:12403614 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6383350 NCBI chr 7:99,731,317...99,770,709
Ensembl chr 7:99,731,318...99,770,772 		JBrowse link
G Pold4 polymerase (DNA-directed), delta 4 part_of
located_in		 IBA
ISO		 (PMID:12403614) GO_Central
MGI
ComplexPortal		 PMID:12403614 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr19:4,281,947...4,283,688
Ensembl chr19:4,281,953...4,283,688 		JBrowse link
DNA replication factor A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcas2 BCAS2 pre-mRNA processing factor part_of
located_in		 ISO (PMID:24332808) MGI
UniProt		 PMID:24332808 GO_REF:0000119 MGI:4834177 NCBI chr 3:103,078,971...103,086,479
Ensembl chr 3:103,078,971...103,086,482 		JBrowse link
G Cdc5l cell division cycle 5-like part_of
located_in		 ISO (PMID:24332808) MGI
UniProt		 PMID:24332808 GO_REF:0000119 MGI:4834177 NCBI chr17:45,702,809...45,744,633
Ensembl chr17:45,702,810...45,744,663 		JBrowse link
G Cdc5lrt1 cell division cycle 5 like, retrotransposed 1 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,074,241...118,076,700
Ensembl chr10:118,074,277...118,076,685 		JBrowse link
G Cdc5lrt10 cell division cycle 5 like, retrotransposed 10 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,187,324...118,190,025
Ensembl chr10:118,187,602...118,190,010 		JBrowse link
G Cdc5lrt4 cell division cycle 5 like, retrotransposed 4 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,094,577...118,097,037
Ensembl chr10:118,094,593...118,097,001 		JBrowse link
G Cdc5lrt5 cell division cycle 5 like, retrotransposed 5 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,160,141...118,162,889
Ensembl chr10:118,160,466...118,162,874 		JBrowse link
G Cdc5lrt6 cell division cycle 5 like, retrotransposed 6 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,165,876...118,168,330
Ensembl chr10:118,165,905...118,168,313 		JBrowse link
G Cdc5lrt7 cell division cycle 5 like, retrotransposed 7 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,171,007...118,173,751
Ensembl chr10:118,171,328...118,173,736 		JBrowse link
G Cdc5lrt8 cell division cycle 5 like, retrotransposed 8 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,176,721...118,179,175
Ensembl chr10:118,176,752...118,179,160 		JBrowse link
G Cdc5lrt9 cell division cycle 5 like, retrotransposed 9 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,182,150...118,184,599
Ensembl chr10:118,182,176...118,184,584 		JBrowse link
G E2f6 E2F transcription factor 6 part_of IC (PMID:15574595) MGI PMID:15574595 NCBI chr12:16,860,932...16,876,753
Ensembl chr12:16,860,964...16,889,743 		JBrowse link
G Ercc5 excision repair cross-complementing rodent repair deficiency, complementation group 5 part_of
located_in		 ISO (PMID:7700386) MGI
UniProt		 PMID:7700386 GO_REF:0000119 MGI:4834177 NCBI chr 1:44,184,084...44,220,399
Ensembl chr 1:44,186,904...44,220,420 		JBrowse link
G Helb helicase (DNA) B part_of
located_in		 ISO (PMID:26774285) MGI
UniProt		 PMID:26774285 GO_REF:0000119 MGI:4834177 NCBI chr10:119,919,513...119,948,917
Ensembl chr10:119,919,513...119,948,892 		JBrowse link
G Plrg1 pleiotropic regulator 1 part_of
located_in		 ISO (PMID:24332808) MGI
UniProt		 PMID:24332808 GO_REF:0000119 MGI:4834177 NCBI chr 3:82,962,845...82,979,598
Ensembl chr 3:82,962,829...82,979,662 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of
located_in		 ISO (PMID:24332808) MGI
UniProt		 PMID:24332808 GO_REF:0000119 MGI:4834177 NCBI chr19:10,872,595...10,886,923
Ensembl chr19:10,872,595...10,886,923 		JBrowse link
G Rpa1 replication protein A1 part_of
located_in		 ISO
IBA		 (PMID:11927569), (PMID:7760808) RGD
GO_Central
MGI
ComplexPortal		 PMID:7503737 PMID:7760808 PMID:8463251 PMID:11927569 GO_REF:0000008 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:2307012 RGD:2307013 NCBI chr11:75,191,085...75,239,478
Ensembl chr11:75,188,992...75,239,150 		JBrowse link
G Rpa2 replication protein A2 part_of
located_in		 ISO
IBA		 (PMID:11927569) RGD
MGI
GO_Central
ComplexPortal		 PMID:7503737 PMID:8463251 PMID:11927569 GO_REF:0000008 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:2307012 RGD:2307013 NCBI chr 4:132,495,671...132,506,057
Ensembl chr 4:132,495,643...132,506,063 		JBrowse link
G Rpa3 replication protein A3 located_in
part_of		 ISO
IBA		 (PMID:11927569), (PMID:7760808) RGD
ComplexPortal
GO_Central
MGI		 PMID:7503737 PMID:7760808 PMID:11927569 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2307013 NCBI chr 6:8,255,936...8,259,141
Ensembl chr 6:8,255,936...8,259,173 		JBrowse link
G Smarcal1 SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 part_of
located_in		 ISO (PMID:19793862), (PMID:19793863) MGI
UniProt		 PMID:19793862 PMID:19793863 GO_REF:0000119 MGI:4834177 NCBI chr 1:72,575,593...72,675,949
Ensembl chr 1:72,622,410...72,672,293 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein part_of
located_in		 ISO (PMID:21055983) MGI
UniProt		 PMID:21055983 GO_REF:0000119 MGI:4834177 NCBI chr15:76,510,437...76,524,129
Ensembl chr15:76,510,202...76,524,158 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A part_of
located_in		 ISO (PMID:7700386) MGI
UniProt		 PMID:7700386 GO_REF:0000119 MGI:4834177 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
replication fork protection complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Timeless timeless circadian clock 1 part_of IBA GO_Central GO_REF:0000033 NCBI chr10:128,067,932...128,088,810
Ensembl chr10:128,067,934...128,088,810 		JBrowse link
G Tipin timeless interacting protein part_of IBA GO_Central GO_REF:0000033 NCBI chr 9:64,188,776...64,212,704
Ensembl chr 9:64,188,863...64,212,706 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19619
      replication fork 82
        nuclear replication fork 47
          nuclear replisome + 29
          replication fork protection complex 2
Path 2
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19619
      organelle 13553
        intracellular organelle 13155
          intracellular membrane-bounded organelle 12011
            nucleus 7488
              nuclear lumen 4317
                nuclear chromosome 290
                  nuclear replication fork 47
                    nuclear replisome + 29
                    replication fork protection complex 2
paths to the root