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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork protection complex
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Accession:GO:0031298 term browser browse the term
Definition:A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling.
Synonyms:exact_synonym: replisome progression complex
 narrow_synonym: Swi1-Swi3 complex;   TIMELESS-TIPIN complex


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replication fork protection complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc45 cell division cycle 45 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Gins2 GINS complex subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:54,151,048...54,163,701
Ensembl chr19:54,151,048...54,163,608
JBrowse link
G Gins4 GINS complex subunit 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:73,584,412...73,596,808
Ensembl chr16:73,584,521...73,596,793
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:77,224,218...77,245,486
Ensembl chr17:77,224,112...77,246,478
JBrowse link
G Timeless timeless circadian regulator IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628
JBrowse link
G Tipin timeless interacting protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:69,753,363...69,768,640
Ensembl chr 8:69,753,373...69,768,305
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:173,761...174,959
Ensembl chr 5:173,744...174,921
JBrowse link
G Top1 DNA topoisomerase I IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:156,635,688...156,717,686
Ensembl chr 3:156,642,464...156,717,686
JBrowse link
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:24,021,674...24,056,073
Ensembl chr15:24,021,674...24,056,073
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      replication fork protection complex 9
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      organelle 13258
        membrane-bounded organelle 11449
          intracellular membrane-bounded organelle 10704
            nucleus 7183
              nuclear lumen 4262
                nuclear chromosome 964
                  nuclear replication fork 40
                    replication fork protection complex 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.