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Gene: E2f6 (E2F transcription factor 6) Mus musculus
Symbol: E2f6
Name: E2F transcription factor 6
Description: Exhibits DNA binding activity and DNA-binding transcription factor activity. Predicted to contribute to DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription involved in G1/S transition of mitotic cell cycle. Predicted to localize to the MLL1 complex and RNA polymerase II transcription factor complex. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human E2F6 (E2F transcription factor 6); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI462434; E2F-6; E2F-binding site-modulating activity protein; E2F6a; E2F6b; EMA; transcription factor E2F6; transcriptional repressor E2F6
Homo sapiens (human) : E2F6 (E2F transcription factor 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : E2f6 (E2F transcription factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f6 (E2F transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F6 (E2F transcription factor 6)
Canis lupus familiaris (dog) : E2F6 (E2F transcription factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f6 (E2F transcription factor 6)
Sus scrofa (pig) : E2F6 (E2F transcription factor 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381216,810,909 - 16,826,752 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371216,817,771 - 16,833,558 (+)NCBIGRCm37mm9NCBIm37
MGSCv361216,836,508 - 16,852,232 (+)NCBImm8
Celera1217,134,343 - 17,150,005 (+)NCBICelera
Cytogenetic Map12 A1.1NCBI
cM Map128.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on E2f6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552292
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.