Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1-naphthyl isothiocyanate | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in increased expression of MMS22L mRNA | CTD | PMID:30723492 | 17beta-estradiol | decreases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of MMS22L mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MMS22L mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MMS22L mRNA | CTD | PMID:32109520 | 6-propyl-2-thiouracil | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of MMS22L mRNA | CTD | PMID:24780913 and PMID:30047161 | acetamide | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | acetamide results in increased expression of MMS22L mRNA | CTD | PMID:31881176 | acrylamide | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of MMS22L mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of MMS22L mRNA | CTD | PMID:22100608 | aflatoxin B1 | increases methylation | ISO | MMS22L (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of MMS22L intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | ISO | MMS22L (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of MMS22L intron | CTD | PMID:30157460 | aflatoxin M1 | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of MMS22L mRNA | CTD | PMID:30928695 | all-trans-retinoic acid | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of MMS22L mRNA | CTD | PMID:33167477 | amitrole | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of MMS22L mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of MMS22L mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MMS22L mRNA | CTD | PMID:20064835 | benzo[a]pyrene | affects methylation | ISO | MMS22L (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MMS22L intron | CTD | PMID:30157460 | benzo[a]pyrene | increases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of MMS22L mRNA | CTD | PMID:26238291 and PMID:32234424 | benzo[a]pyrene diol epoxide I | increases expression | ISO | MMS22L (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MMS22L mRNA | CTD | PMID:26063408 | bisphenol A | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of MMS22L mRNA | CTD | PMID:29275510 and PMID:33670352 | bisphenol A | increases methylation | ISO | Mms22l (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of MMS22L gene | CTD | PMID:28505145 | bisphenol A | affects expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of MMS22L mRNA | CTD | PMID:25181051 and PMID:32145629 | butanal | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of MMS22L mRNA | CTD | PMID:26079696 | cadmium dichloride | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased expression of MMS22L mRNA | CTD | PMID:33453195 | calcitriol | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of MMS22L mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | MMS22L (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of MMS22L mRNA | CTD | PMID:21592394 | cisplatin | decreases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Cisplatin results in decreased expression of MMS22L mRNA | CTD | PMID:22023808 | cobalt dichloride | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | cobaltous chloride results in increased expression of MMS22L mRNA | CTD | PMID:24386269 | coumarin | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | coumarin results in increased expression of MMS22L mRNA | CTD | PMID:18480146 | crotonaldehyde | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | 2-butenal results in decreased expression of MMS22L mRNA | CTD | PMID:20471460 | Cuprizon | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of MMS22L mRNA | CTD | PMID:26577399 and PMID:27523638 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of MMS22L mRNA | CTD | PMID:21266533 | folic acid | increases expression | EXP | | 6480464 | Folic Acid results in increased expression of MMS22L mRNA | CTD | PMID:25629700 | furan | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | furan results in increased expression of MMS22L mRNA | CTD | PMID:25539665 and PMID:26194646 | lidocaine | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Lidocaine results in increased expression of MMS22L mRNA | CTD | PMID:35283115 | melphalan | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Melphalan results in decreased expression of MMS22L mRNA | CTD | PMID:22363485 | methimazole | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of MMS22L mRNA | CTD | PMID:30047161 | oxaliplatin | decreases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | oxaliplatin results in decreased expression of MMS22L mRNA | CTD | PMID:25729387 | oxaliplatin | multiple interactions | ISO | Mms22l (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of MMS22L mRNA | CTD | PMID:25729387 | ozone | decreases expression | EXP | | 6480464 | Ozone results in decreased expression of MMS22L mRNA | CTD | PMID:24336422 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of MMS22L mRNA more ... | CTD | PMID:25658374 more ... | paracetamol | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of MMS22L mRNA | CTD | PMID:33387578 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of MMS22L mRNA | CTD | PMID:23091169 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of MMS22L mRNA | CTD | PMID:20813756 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of MMS22L mRNA | CTD | PMID:20813756 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of MMS22L mRNA | CTD | PMID:30047161 | propanal | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | propionaldehyde results in decreased expression of MMS22L mRNA | CTD | PMID:26079696 | sodium dichromate | affects expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | sodium bichromate affects the expression of MMS22L mRNA | CTD | PMID:22110744 | sulfadimethoxine | increases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of MMS22L mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of MMS22L mRNA | CTD | PMID:31533062 | testosterone | multiple interactions | ISO | MMS22L (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of MMS22L mRNA | CTD | PMID:21592394 | testosterone | decreases expression | ISO | MMS22L (Homo sapiens) | 6480464 | Testosterone results in decreased expression of MMS22L mRNA | CTD | PMID:21592394 | thioacetamide | affects expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Thioacetamide affects the expression of MMS22L mRNA | CTD | PMID:34492290 | topotecan | multiple interactions | ISO | Mms22l (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of MMS22L mRNA | CTD | PMID:25729387 | topotecan | decreases expression | ISO | Mms22l (Rattus norvegicus) | 6480464 | Topotecan results in decreased expression of MMS22L mRNA | CTD | PMID:25729387 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of MMS22L mRNA | CTD | PMID:19042947 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of MMS22L mRNA | CTD | PMID:33045310 | |