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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of proteasomal ubiquitin-dependent protein catabolic process
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Accession:GO:0032434 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.


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regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase involved_in ISO
ISS		 (PMID:22609986)
GO_REF:0000024		 RGD
UniProt		 PMID:22609986 GO_REF:0000024 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073 		JBrowse link
G Commd1 copper metabolism domain containing 1 involved_in ISO
IBA		 (PMID:17183367)
GO_REF:0000033		 RGD
GO_Central		 PMID:17183367 GO_REF:0000033 NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501 		JBrowse link
G Desi1 desumoylating isopeptidase 1 involved_in ISO
IEA		 (PMID:29666234)
GO_REF:0000107		 RGD
Ensembl		 PMID:29666234 GO_REF:0000107 NCBI chr 7:113,519,974...113,542,834
Ensembl chr 7:113,519,980...113,542,845 		JBrowse link
G Foxf2 forkhead box F2 involved_in ISO (PMID:29374064) RGD PMID:29374064 NCBI chr17:32,835,730...32,842,547
Ensembl chr17:32,836,777...32,842,176 		JBrowse link
G Glmn glomulin, FKBP associated protein acts_upstream_of_or_within ISO (PMID:22405651) RGD PMID:22405651 NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420 		JBrowse link
G Gna12 G protein subunit alpha 12 involved_in ISO
ISS		 (PMID:22609986)
(MGI:5448916|PMID:22609986)
GO_REF:0000024		 RGD
UniProt		 PMID:22609986 GO_REF:0000024 MGI:5448916 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein involved_in ISO (PMID:12643283) RGD PMID:12643283 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695 		JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein involved_in ISO (PMID:19435460) RGD PMID:19435460 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K acts_upstream_of_or_within ISO (PMID:18710920) RGD PMID:18710920 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO (PMID:15280365), (PMID:27113755) RGD PMID:15280365 PMID:27113755 NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:20228063)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:20228063 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO MGI:3582610 (PMID:19056892) RGD PMID:19056892 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Xpo1 exportin 1 involved_in ISO
IEA		 (PMID:29666234)
GO_REF:0000107		 RGD
Ensembl		 PMID:29666234 GO_REF:0000107 NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Zfp418 zinc finger protein 418 involved_in IMP
ISO
ISS		 PMID:33249983
(MGI:6789914|PMID:33249983)
GO_REF:0000024		 RGD
UniProt		 PMID:33249983 PMID:33249983 GO_REF:0000024 MGI:6789914, RGD:329955556 NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3808636|PMID:18678708)		 UniProt
Ensembl
RGD		 PMID:18678708 GO_REF:0000024 GO_REF:0000107 MGI:3808636 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Camlg calcium modulating ligand involved_in ISO UniProtKB:Q9H9V4 (PMID:20553626) RGD PMID:20553626 NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552 		JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23398316) RGD PMID:23398316 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (PMID:24949970) RGD PMID:24949970 NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISO UniProtKB:P19784|UniProtKB:P25686|UniProtKB:P67870 (PMID:28031292) RGD PMID:28031292 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO UniProtKB:P25686|UniProtKB:P67870|UniProtKB:P68400 (PMID:28031292) RGD PMID:28031292 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080 		JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO (PMID:28031292) RGD PMID:28031292 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28263186) RGD PMID:28263186 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H involved_in ISO
IEA		 (PMID:32269044)
GO_REF:0000107		 RGD
Ensembl		 PMID:32269044 GO_REF:0000107 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G ENSRNOG00000069696 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 2:11,225,135...11,226,004 JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in ISO
IBA
IEA
ISS		 (PMID:15313915)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
Ensembl
UniProt		 PMID:15313915 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISO
IEA		 (MGI:3807767|PMID:11546783)
GO_REF:0000107		 RGD
Ensembl		 PMID:11546783 GO_REF:0000107 MGI:3807767 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:24904118)
GO:0010628 (MGI:5603002|PMID:24904118)		 RGD PMID:24904118 MGI:5603002 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24613385)		 UniProt
Ensembl
RGD		 PMID:24613385 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Klhl40 kelch-like family member 40 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:24960163)		 GO_Central
RGD		 PMID:24960163 GO_REF:0000033 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Map1a microtubule-associated protein 1A involved_in ISO (MGI:5703671|PMID:26609151) RGD PMID:26609151 MGI:5703671 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Mtm1 myotubularin 1 acts_upstream_of_or_within ISO MGI:2450997 (PMID:23695157) RGD PMID:23695157 NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860 		JBrowse link
G N4bp1 Nedd4 binding protein 1 involved_in ISO
IBA		 (MGI:3829128|PMID:17592138)
GO_REF:0000033		 RGD
GO_Central		 PMID:17592138 GO_REF:0000033 MGI:3829128 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:22522597) RGD PMID:22522597 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO		 GO_REF:0000107
(PMID:26678539)		 Ensembl
RGD		 PMID:26678539 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA		 (PMID:17015834)
GO_REF:0000107		 RGD
Ensembl		 PMID:17015834 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (PMID:21715333) RGD PMID:21715333 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Phf20l1 PHD finger protein 20-like 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24492612)		 UniProt
Ensembl
RGD		 PMID:24492612 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526 		JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5897550|PMID:21804542)		 UniProt
RGD		 PMID:21804542 GO_REF:0000024 MGI:5897550 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106 		JBrowse link
G Rybp RING1 and YY1 binding protein involved_in ISO (PMID:27060496) RGD PMID:27060496 NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316 		JBrowse link
G Senp1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO MGI:3818522 (PMID:17981124) RGD PMID:17981124 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16611981)		 Ensembl
RGD		 PMID:16611981 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 acts_upstream_of_or_within ISO (PMID:22285184) RGD PMID:22285184 NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in ISO
IEA		 (PMID:11278372)
GO_REF:0000107		 RGD
Ensembl		 PMID:11278372 GO_REF:0000107 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
G Tlk2 tousled-like kinase 2 involved_in ISO (PMID:20016786) RGD PMID:20016786 NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IBA
IEA
ISS		 (PMID:23213251)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
Ensembl
UniProt		 PMID:23213251 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117 		JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO MGI:5588394 (PMID:31537781) RGD PMID:31537781 NCBI chr 8:45,112,737...45,116,345 JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(PMID:20351172)		 UniProt
GO_Central
TreeGrafter
RGD		 PMID:20351172 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:205,765,309...205,769,234
Ensembl chr 1:205,745,120...205,816,520 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:23770237) RGD PMID:23770237 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Usp26 ubiquitin specific peptidase 26 involved_in ISO (PMID:28839133)
(MGI:5926846|PMID:28839133)		 RGD PMID:28839133 MGI:5926846 NCBI chr  X:131,317,200...131,363,964
Ensembl chr  X:131,319,194...131,363,970 		JBrowse link
G Usp38 ubiquitin specific peptidase 38 involved_in ISO (PMID:34102342) RGD PMID:34102342 NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 involved_in ISO
IEA		 (PMID:26678539)
GO_REF:0000107		 RGD
Ensembl		 PMID:26678539 GO_REF:0000107 NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355 		JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO (PMID:33378666) RGD PMID:33378666 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:22354037) RGD PMID:22354037 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pabpn1l PABPN1 like acts_upstream_of_or_within ISO (PMID:32558204) RGD PMID:32558204 NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366 		JBrowse link
G Styx serine/threonine/tyrosine interacting protein involved_in ISO
IBA		 (PMID:28007894)
GO_REF:0000033		 RGD
GO_Central		 PMID:28007894 GO_REF:0000033 NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524 		JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07001519.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118
G Akt1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:23512198)
GO_REF:0000107
(PMID:15937334)		 RGD
Ensembl		 PMID:15937334 PMID:23512198 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ankib1 ankyrin repeat and IBR domain containing 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781 		JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245 		JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2446434|MGI:3587769|MGI:3691571 (PMID:23152632) RGD PMID:23152632 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Aurka aurora kinase A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:17060449)		 Ensembl
RGD		 PMID:17060449 GO_REF:0000107 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Axin1 axin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:16601693)
GO_REF:0000118
GO_REF:0000033		 Ensembl
RGD
TreeGrafter
GO_Central		 PMID:16601693 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bag2 BAG cochaperone 2 NOT|involved_in ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Bbs7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within ISO UniProtKB:Q99496 (PMID:22302990) RGD PMID:22302990 NCBI chr 2:119,434,760...119,474,665
Ensembl chr 2:119,434,760...119,474,396 		JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:25974097) RGD PMID:25974097 NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610 		JBrowse link
G Chfr checkpoint with forkhead and ring finger domains acts_upstream_of_or_within ISO (PMID:22285184) RGD PMID:22285184 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
G Clu clusterin involved_in ISO
ISS
IEA
IBA		 (PMID:20068069)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118		 RGD
UniProt
Ensembl
GO_Central
TreeGrafter		 PMID:20068069 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cop1 COP1, E3 ubiquitin ligase involved_in ISO (PMID:19805145) RGD PMID:19805145 NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISO
IEA		 (PMID:11955436), (PMID:19364825)
GO_REF:0000107		 RGD
Ensembl		 PMID:11955436 PMID:19364825 GO_REF:0000107 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Csnk1d casein kinase 1, delta involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(MGI:3849793|PMID:19414593)		 UniProt
GO_Central
TreeGrafter
RGD		 PMID:19414593 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:3849793 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614 		JBrowse link
G Csnk1e casein kinase 1, epsilon involved_in ISO
IBA		 (MGI:3849793|PMID:19414593)
GO_REF:0000033		 RGD
GO_Central		 PMID:19414593 GO_REF:0000033 MGI:3849793 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12805222)		 Ensembl
RGD		 PMID:12805222 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dda1 DET1 and DDB1 associated 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,156,310...18,163,938
Ensembl chr16:18,156,386...18,163,937 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Det1 DET1 partner of COP1 E3 ubiquitin ligase involved_in ISO
IBA		 UniProtKB:Q8NHY2 (PMID:14739464)
GO_REF:0000033		 RGD
GO_Central		 PMID:14739464 GO_REF:0000033 NCBI chr 1:132,749,736...132,765,963
Ensembl chr 1:132,749,756...132,765,923 		JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO
IBA		 (PMID:15936278)
GO_REF:0000033		 RGD
GO_Central		 PMID:15936278 GO_REF:0000033 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Fbxo22 F-box protein 22 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:19319192)		 GO_Central
RGD		 PMID:19319192 GO_REF:0000033 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148 		JBrowse link
G Fbxw8 F-box and WD repeat domain containing 8 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6148490|PMID:29153991)		 Ensembl
RGD		 PMID:29153991 GO_REF:0000107 MGI:6148490 NCBI chr12:38,426,466...38,517,076
Ensembl chr12:38,426,444...38,516,424 		JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:25684205)		 UniProt
RGD		 PMID:25684205 GO_REF:0000024 NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (MGI:5501380|PMID:23707074) RGD PMID:23707074 MGI:5501380 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:2387010 (PMID:17189825) RGD PMID:17189825 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO
IBA
IEA		 (PMID:25897075)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:25897075 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:1924375|MGI:3039600 (PMID:22660580)
GO_REF:0000033
(PMID:19364825), (PMID:22660580), (PMID:25897075)		 Ensembl
RGD
GO_Central		 PMID:19364825 PMID:22660580 PMID:25897075 GO_REF:0000033 GO_REF:0000107 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO
IBA		 (PMID:24613385)
GO_REF:0000033		 RGD
GO_Central		 PMID:24613385 GO_REF:0000033 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO
IBA		 (PMID:24613385)
GO_REF:0000033		 RGD
GO_Central		 PMID:24613385 GO_REF:0000033 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 involved_in ISO (PMID:16831871) RGD PMID:16831871 NCBI chr 1:69,165,394...69,189,062
Ensembl chr 1:69,165,572...69,244,593 		JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861437|MGI:3039600 (PMID:22660580)		 Ensembl
RGD		 PMID:22660580 GO_REF:0000107 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Klhl40 kelch-like family member 40 involved_in ISO (MGI:5700633|PMID:25940086) RGD PMID:25940086 MGI:5700633 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (MGI:4454597|PMID:20457918) RGD PMID:20457918 MGI:4454597 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6148490|PMID:29153991)		 Ensembl
RGD		 PMID:29153991 GO_REF:0000107 MGI:6148490 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:11278372) RGD PMID:11278372 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:25818168), (PMID:27323397)
(MGI:5897550|PMID:21804542)		 RGD PMID:21804542 PMID:25818168 PMID:27323397 MGI:5897550 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 involved_in ISO (PMID:16707496) RGD PMID:16707496 NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694 		JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO
ISS		 (PMID:27588481)
GO_REF:0000024		 RGD
UniProt		 PMID:27588481 GO_REF:0000024 NCBI chr 1:222,114,988...222,116,294
Ensembl chr 1:222,112,591...222,116,396 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 involved_in ISO (MGI:5487503|PMID:22406621) RGD PMID:22406621 MGI:5487503 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Plk1 polo-like kinase 1 involved_in ISO
IEA
ISS		 (PMID:19473992)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19473992 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA		 (PMID:17030191)
GO_REF:0000107		 RGD
Ensembl		 PMID:17030191 GO_REF:0000107 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA GO_REF:0000107
GO_REF:0000118		 Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psen1 presenilin 1 involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
IEA
ISS		 (PMID:16023600)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16023600 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:104,656,809...104,665,122
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19785988)		 UniProt
RGD		 PMID:19785988 GO_REF:0000024 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein involved_in ISO (PMID:26296656) RGD PMID:26296656 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695 		JBrowse link
G Rbx1 ring-box 1 involved_in ISO UniProtKB:Q7L5Y6 (PMID:14739464) RGD PMID:14739464 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 involved_in ISO (PMID:19483087) RGD PMID:19483087 NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167 		JBrowse link
G Rnf14 ring finger protein 14 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685 		JBrowse link
G Rnf144a ring finger protein 144A involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 6:42,899,767...43,019,769
Ensembl chr 6:42,903,174...43,020,012 		JBrowse link
G Rnf144b ring finger protein 144B involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760 		JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:18363970), (PMID:23926250)		 GO_Central
RGD		 PMID:18363970 PMID:23926250 GO_REF:0000033 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614 		JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222 		JBrowse link
G Rnf19b ring finger protein 19B involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380 		JBrowse link
G Rnf217 ring finger protein 217 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:26,016,668...26,108,736
Ensembl chr 1:26,015,728...26,108,736 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in IMP
IEA
IBA
ISO		 PMID:22128169
GO_REF:0000118
GO_REF:0000033
(PMID:22128169)		 TreeGrafter
GO_Central
RGD		 PMID:22128169 PMID:22128169 GO_REF:0000033 GO_REF:0000118, RGD:13673844 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24681946)
GO_REF:0000107
(MGI:5574427|PMID:24681946)		 UniProt
RGD
Ensembl		 PMID:24681946 GO_REF:0000024 GO_REF:0000107 MGI:5574427 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:27457971) RGD PMID:27457971 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:11146632) RGD PMID:11146632 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISO (PMID:18408734) RGD PMID:18408734 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Sumo2 small ubiquitin-like modifier 2 involved_in ISO (PMID:18408734) RGD PMID:18408734 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:15053879) RGD PMID:15053879 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO
IBA		 (MGI:4457446|PMID:20410507)
GO_REF:0000033		 RGD
GO_Central		 PMID:20410507 GO_REF:0000033 MGI:4457446 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trib2 tribbles pseudokinase 2 involved_in ISO (MGI:4457446|PMID:20410507) RGD PMID:20410507 MGI:4457446 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 IMP RGD PMID:12750002 RGD:1299567 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 involved_in ISO (PMID:19098288) RGD PMID:19098288 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:9452483) RGD PMID:9452483 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Zer1 zyg-11 related, cell cycle regulator involved_in ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 3:13,369,688...13,397,524
Ensembl chr 3:13,369,688...13,397,420 		JBrowse link
G Zfand2a zinc finger AN1-type containing 2A acts_upstream_of_or_within ISO MGI:3664591 (PMID:16973439) RGD PMID:16973439 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677 		JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator involved_in ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 5:122,985,548...123,042,735
Ensembl chr 5:122,992,147...123,042,736 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20889502)		 UniProt
RGD		 PMID:20889502 GO_REF:0000024 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      catabolic process 2859
        regulation of catabolic process 1115
          regulation of ubiquitin-dependent protein catabolic process 177
            regulation of proteasomal ubiquitin-dependent protein catabolic process 138
              negative regulation of proteasomal ubiquitin-dependent protein catabolic process + 43
              positive regulation of proteasomal ubiquitin-dependent protein catabolic process + 85
              regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process + 2
              regulation of anaphase-promoting complex-dependent catabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      organic substance metabolic process 11328
        macromolecule metabolic process 9578
          protein metabolic process 4746
            proteolysis 1615
              proteolysis involved in protein catabolic process 862
                modification-dependent protein catabolic process 683
                  ubiquitin-dependent protein catabolic process 664
                    proteasome-mediated ubiquitin-dependent protein catabolic process 455
                      regulation of proteasomal ubiquitin-dependent protein catabolic process 138
                        negative regulation of proteasomal ubiquitin-dependent protein catabolic process + 43
                        positive regulation of proteasomal ubiquitin-dependent protein catabolic process + 85
                        regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process + 2
                        regulation of anaphase-promoting complex-dependent catabolic process + 2
paths to the root