Gene: Sirt2 (sirtuin 2) Rattus norvegicus
Symbol: Sirt2
Name: sirtuin 2
Description: ENCODES a protein that exhibits NAD-dependent protein deacetylase activity; tubulin deacetylase activity; beta-tubulin binding (ortholog); INVOLVED IN central nervous system development; myelination in peripheral nervous system; negative regulation of apoptotic process; PARTICIPATES IN histone modification pathway; Sirtuin mediated pathway; ASSOCIATED WITH Glioma; Intermittent Claudication; Non-alcoholic Fatty Liver Disease; FOUND IN cytoplasm; glial cell projection; juxtaparanode region of axon; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5E5 antigen; MGC105900; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; regulatory protein SIR2 homolog 2; SIR2-like protein 2; sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae); sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
Orthologs:
Homo sapiens : SIRT2 (sirtuin 2)  HGNC
Mus musculus : Sirt2 (sirtuin 2)  MGI
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0186,948,881 - 86,971,954 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0188,130,012 - 88,153,086 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4183,873,578 - 83,896,121 (+)NCBIRGSC3.4rn4RGSC3.4
Celera178,446,589 - 78,469,133 (+)NCBI
Cytogenetic Map1q21NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sirt2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 621481
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-07-05
Status: ACTIVE