Gene: Gba (glucosidase, beta, acid) Rattus norvegicus
Symbol: Gba
Name: glucosidase, beta, acid
Description: ENCODES a protein that exhibits glucosylceramidase activity; receptor binding (ortholog); INVOLVED IN regulation of water loss via skin; response to estrogen; response to glucocorticoid; PARTICIPATES IN sphingolipid metabolic pathway; ASSOCIATED WITH Gaucher Disease (ortholog); Gaucher Disease, Perinatal Lethal (ortholog); Gaucher Disease, Type Iiic (ortholog); FOUND IN lysosomal lumen (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 9-cis-retinoic acid (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glucocerebrosidase; LOC684536; MGC188451; similar to Glucosylceramidase precursor (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map2q34 NCBI
RGSC Genome Assembly v5.02207,931,042 - 207,937,062+NCBI
Rat Celera Assembly2168,551,737 - 168,557,757+NCBI
Model
This feature is not available in GBrowse. This may be because it does not have a position on the current reference assembly, or because it maps to either the mitochondrial (MT) chromosome or an unknown (Un) chromosome.
Browse the genome for the Rat reference assembly: v3.4


Disease Annotations
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References - curated
References - uncurated
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Genomics

Comparative Map Data
Position Markers

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on Gba
Entrez Gene
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RGD Object Information
RGD ID: 1589149
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2014-04-08
Status: ACTIVE