Gene: Gba (glucosylceramidase beta) Rattus norvegicus
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Symbol: Gba
Name: glucosylceramidase beta
Description: ENCODES a protein that exhibits glucosylceramidase activity; hydrolase activity (ortholog); receptor binding (ortholog); INVOLVED IN beta-glucoside catabolic process; regulation of water loss via skin; response to dexamethasone; PARTICIPATES IN Fabry disease pathway; Gaucher disease pathway; globoid cell leukodystrophy disease pathway; ASSOCIATED WITH autosomal recessive juvenile Parkinson disease 2 (ortholog); Dementia (ortholog); dementia (ortholog); FOUND IN lysosome; extracellular exosome (ortholog); extracellular space (ortholog); INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 3,3',5-triiodo-L-thyronine; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glucocerebrosidase; glucosidase, beta, acid; glucosylceramidase; LOC684536; MGC188451; similar to Glucosylceramidase precursor (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)
Orthologs:
Homo sapiens (human) : GBA (glucosylceramidase beta)  HGNC  AGR
Mus musculus (house mouse) : Gba (glucosidase, beta, acid)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Gba (glucosylceramidase beta)
Canis lupus familiaris (dog) : GBA (glucosylceramidase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gba (glucosylceramidase beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02188,511,781 - 188,522,602 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02207,931,042 - 207,937,062 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2168,551,737 - 168,557,757 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gba
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1589149
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE