Lrrk2 (leucine-rich repeat kinase 2)

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Keyword

Gene: Lrrk2 (leucine-rich repeat kinase 2) Rattus norvegicus

Symbol:

Lrrk2

Name:

leucine-rich repeat kinase 2

Description:

ENCODES a protein that exhibits GTP binding (ortholog); GTP-dependent protein kinase activity (ortholog); GTPase activator activity (ortholog); INVOLVED IN cellular response to organic cyclic compound; activation of MAPK activity (ortholog); activation of MAPKK activity (ortholog); PARTICIPATES IN Parkinson disease pathway; ASSOCIATED WITH Amyotrophic Lateral Sclerosis (ortholog); Arthritis, Rheumatoid (ortholog); Colitis (ortholog); FOUND IN axon; cytoplasm; dendrite; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; copper(2+) sulfate (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

leucine-rich repeat serine/threonine-protein kinase 2

Orthologs:

Homo sapiens : LRRK2 (leucine-rich repeat kinase 2) HGNC
Mus musculus : Lrrk2 (leucine-rich repeat kinase 2) MGI

Allele / Splice:

Lrrk1^em1SageLrrk2^em1Sage Lrrk2^em1Sage

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	7	q35		NCBI
RGSC Genome Assembly v5.0	7	132,531,605 - 132,693,763	+	NCBI
RGSC Genome Assembly v3.4	7	130,105,902 - 130,267,747	+	NCBI
Rat Celera Assembly	7	119,264,946 - 119,423,875	+	NCBI