Gna12 (G protein subunit alpha 12)

Gene: Gna12 (G protein subunit alpha 12) Rattus norvegicus

Analyze

Symbol:

Gna12

Name:

G protein subunit alpha 12

RGD ID:

71018

Description:

Enables D5 dopamine receptor binding activity. Involved in response to xenobiotic stimulus. Acts upstream of or within G protein-coupled receptor signaling pathway; negative regulation of vascular associated smooth muscle cell migration; and negative regulation of vascular associated smooth muscle cell proliferation. Located in brush border membrane. Orthologous to human GNA12 (G protein subunit alpha 12); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

g alpha-12; G-protein subunit alpha-12; guanine nucleotide binding protein (G protein) alpha 12; guanine nucleotide binding protein, alpha 12; guanine nucleotide-binding protein subunit alpha-12; heterotrimeric guanine nucleotide-binding protein 1m1; Hg1m1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GNA12 (G protein subunit alpha 12)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Gna12 (guanine nucleotide binding protein, alpha 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gna12 (G protein subunit alpha 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GNA12 (G protein subunit alpha 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GNA12 (G protein subunit alpha 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gna12 (G protein subunit alpha 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GNA12 (G protein subunit alpha 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GNA12 (G protein subunit alpha 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gna12 (G protein subunit alpha 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GNA13 (G protein subunit alpha 13)	HGNC	OrthoDB
Homo sapiens (human):	FOXL3 (forkhead box L3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	GNA12 (G protein subunit alpha 12)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gna12 (guanine nucleotide binding protein, alpha 12)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gna12a (guanine nucleotide binding protein (G protein) alpha 12a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gpa-12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	cta	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	18,919,629 - 19,000,185 (+)	NCBI		GRCr8
mRatBN7.2	12	13,805,580 - 13,886,255 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	13,805,698 - 13,886,255 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	14,613,893 - 14,694,474 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	15,237,164 - 15,317,743 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	14,264,094 - 14,344,680 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	15,890,202 - 15,971,212 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	15,890,170 - 15,971,212 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	17,889,996 - 17,970,852 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	14,275,708 - 14,354,843 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	14,305,635 - 14,384,771 (+)	NCBI
Celera	12	15,567,135 - 15,646,904 (+)	NCBI		Celera
Cytogenetic Map	12	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

immunodeficiency 11A (ISO)

Myocardial Ischemia (ISO)

ulcerative colitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (ISO)

1,1,1-trichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

benzatropine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

C60 fullerene (EXP)

calcidiol (EXP)

carbamazepine (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

chlorpyrifos (EXP)

clofibrate (ISO)

clozapine (EXP,ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

Cuprizon (EXP,ISO)

decabromodiphenyl ether (EXP)

dexamethasone (ISO)

dextran sulfate (ISO)

diazinon (EXP)

dichloroacetic acid (ISO)

diethylstilbestrol (EXP)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (EXP,ISO)

finasteride (EXP)

fipronil (EXP)

flavonoids (EXP)

fluoxetine (EXP)

folic acid (ISO)

gamma-hexachlorocyclohexane (EXP)

genistein (EXP)

glyphosate (ISO)

haloperidol (EXP)

hydrogen cyanide (ISO)

indometacin (ISO)

inulin (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

ozone (EXP,ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium cyanide (ISO)

silicon dioxide (ISO)

sodium arsenite (EXP)

sunitinib (ISO)

titanium dioxide (ISO)

triphenyl phosphate (EXP)

troglitazone (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-modulating G protein-coupled receptor signaling pathway (IBA)

cell differentiation (ISO)

dopamine receptor signaling pathway (TAS)

embryonic digit morphogenesis (ISO)

G protein-coupled receptor signaling pathway (IMP)

in utero embryonic development (ISO)

intracellular signal transduction (ISO)

negative regulation of vascular associated smooth muscle cell migration (IMP)

negative regulation of vascular associated smooth muscle cell proliferation (IMP)

regulation of blood pressure (ISO)

regulation of cell shape (ISO)

regulation of fibroblast migration (ISO,ISS)

regulation of proteasomal ubiquitin-dependent protein catabolic process (ISO,ISS)

regulation of TOR signaling (ISO,ISS)

response to xenobiotic stimulus (IEP)

Rho protein signal transduction (IBA,ISO)

Cellular Component

brush border membrane (IBA,IDA)

cytoplasm (IBA)

heterotrimeric G-protein complex (IBA,TAS)

lateral plasma membrane (ISO)

neuron projection (ISO)

neuronal cell body (ISO)

Molecular Function

D5 dopamine receptor binding (IBA,IPI)

G protein activity (ISO)

G-protein beta/gamma-subunit complex binding (IBA)

GTP binding (IEA)

GTPase activity (IBA)

metal ion binding (IEA)

protein binding (ISO)

protein phosphatase 2A binding (ISO)

protein phosphatase regulator activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

eicosanoid signaling pathway (ISO)

endothelin signaling pathway (ISO)

long term depression (IEA)

mitogen activated protein kinase signaling pathway (IEA)

sphingosine 1-phosphate signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2.	Wang Y, etal., Circulation. 2018 Jul 3;138(1):48-63. doi: 10.1161/CIRCULATIONAHA.117.032398. Epub 2018 Feb 16.
10.	Galpha12- and Galpha13-protein subunit linkage of D5 dopamine receptors in the nephron.	Zheng S, etal., Hypertension 2003 Mar;41(3):604-10.

Additional References at PubMed

PMID:9305907	PMID:10037795	PMID:12077299	PMID:15525651	PMID:15826947	PMID:17533154	PMID:18155002	PMID:18480127	PMID:19043202	PMID:19095998	PMID:21423176	PMID:21633357
PMID:22609986	PMID:25989500

Genomics

Comparative Map Data

Gna12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	18,919,629 - 19,000,185 (+)	NCBI		GRCr8
mRatBN7.2	12	13,805,580 - 13,886,255 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	13,805,698 - 13,886,255 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	14,613,893 - 14,694,474 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	15,237,164 - 15,317,743 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	14,264,094 - 14,344,680 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	15,890,202 - 15,971,212 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	15,890,170 - 15,971,212 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	17,889,996 - 17,970,852 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	14,275,708 - 14,354,843 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	14,305,635 - 14,384,771 (+)	NCBI
Celera	12	15,567,135 - 15,646,904 (+)	NCBI		Celera
Cytogenetic Map	12	q11	NCBI

GNA12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	2,728,105 - 2,844,308 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	2,728,105 - 2,844,308 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	2,767,739 - 2,883,942 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	2,734,265 - 2,850,485 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	2,540,980 - 2,657,200	NCBI
Celera	7	2,736,337 - 2,852,578 (-)	NCBI		Celera
Cytogenetic Map	7	p22.3-p22.2	NCBI
HuRef	7	2,686,290 - 2,802,582 (-)	NCBI		HuRef
CHM1_1	7	2,767,404 - 2,883,659 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	2,841,649 - 2,957,882 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	2,815,641 - 2,931,835 (-)	NCBI

Gna12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	140,745,699 - 140,816,186 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	140,744,163 - 140,816,186 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	140,759,944 - 140,830,431 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	140,758,408 - 140,830,431 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	141,235,898 - 141,306,385 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	141,012,418 - 141,082,905 (-)	NCBI		MGSCv36	mm8
Celera	5	137,821,586 - 137,847,268 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	79.3	NCBI

Gna12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955460	12,534,168 - 12,622,537 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955460	12,534,210 - 12,628,090 (+)	NCBI	ChiLan1.0	ChiLan1.0

GNA12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	7,686,160 - 7,801,169 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	56,010,860 - 56,125,869 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	2,989,832 - 3,104,848 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	3,081,004 - 3,147,356 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

GNA12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	14,375,144 - 14,476,018 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	14,413,576 - 14,473,764 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	15,830,291 - 15,937,728 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	14,493,454 - 14,600,978 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	14,493,362 - 14,600,974 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	14,298,807 - 14,406,220 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	14,226,168 - 14,333,618 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	14,511,840 - 14,619,319 (+)	NCBI		UU_Cfam_GSD_1.0

Gna12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	142,508,304 - 142,603,457 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936823	447,917 - 543,140 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936823	447,979 - 543,134 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GNA12
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	2,004,471 - 2,105,952 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	2,002,494 - 2,105,937 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	1,963,865 - 2,020,488 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GNA12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	18,778,768 - 18,890,420 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	18,778,847 - 18,888,922 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666090	2,884,815 - 2,998,712 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gna12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	30,133,435 - 30,245,079 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	30,134,262 - 30,245,079 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gna12
189 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	582
Count of miRNA genes:	287
Interacting mature miRNAs:	352
Transcripts:	ENSRNOT00000001654
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	1	19611090	Rat
10755457	Coatc14	Coat color QTL 14		0.01759	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	12	1	22591684	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	23297788	Rat
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	29333307	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	34851688	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
1600391	Edcs2	Endometrial carcinoma susceptibility QTL2	3.5	0.01	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	12	6833190	17870186	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	8449490	28302290	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	8525423	28064601	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	9318216	32103380	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	11073825	24234895	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	28064557	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13008296	19212979	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	13635523	30827399	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	13635523	35682913	Rat

Markers in Region

RH128312

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	13,885,851 - 13,886,037 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	15,970,809 - 15,970,994	NCBI	Rnor6.0
Rnor_5.0	12	17,970,449 - 17,970,634	UniSTS	Rnor5.0
RGSC_v3.4	12	14,356,391 - 14,356,576	UniSTS	RGSC3.4
Celera	12	15,646,501 - 15,646,686	UniSTS
RH 3.4 Map	12	177.4	UniSTS
Cytogenetic Map	12	q11	UniSTS

RH144209

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	13,883,483 - 13,883,584 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	15,968,441 - 15,968,541	NCBI	Rnor6.0
Rnor_5.0	12	17,968,081 - 17,968,181	UniSTS	Rnor5.0
RGSC_v3.4	12	14,354,023 - 14,354,123	UniSTS	RGSC3.4
Celera	12	15,644,133 - 15,644,233	UniSTS
RH 3.4 Map	12	177.6	UniSTS
Cytogenetic Map	12	q11	UniSTS

BE097282

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	13,875,365 - 13,875,546 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	15,960,325 - 15,960,505	NCBI	Rnor6.0
Rnor_5.0	12	17,959,963 - 17,960,143	UniSTS	Rnor5.0
RGSC_v3.4	12	14,345,973 - 14,346,153	UniSTS	RGSC3.4
Celera	12	15,636,104 - 15,636,284	UniSTS
RH 3.4 Map	12	176.8	UniSTS
Cytogenetic Map	12	q11	UniSTS

RH138328

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	13,886,570 - 13,886,710 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	15,971,528 - 15,971,667	NCBI	Rnor6.0
Rnor_5.0	12	17,971,168 - 17,971,307	UniSTS	Rnor5.0
RGSC_v3.4	12	14,357,110 - 14,357,249	UniSTS	RGSC3.4
Celera	12	15,647,220 - 15,647,359	UniSTS
RH 3.4 Map	12	177.4	UniSTS
Cytogenetic Map	12	q11	UniSTS

RH141162

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	13,882,777 - 13,882,963 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	15,967,735 - 15,967,920	NCBI	Rnor6.0
Rnor_5.0	12	17,967,375 - 17,967,560	UniSTS	Rnor5.0
RGSC_v3.4	12	14,353,317 - 14,353,502	UniSTS	RGSC3.4
Celera	12	15,643,427 - 15,643,612	UniSTS
RH 3.4 Map	12	202.4	UniSTS
Cytogenetic Map	12	q11	UniSTS

OMY6173INRA

Rat Assembly	Chr	Position (strand)	Source
Celera	4	89,392,817 - 89,393,473	UniSTS
Celera	12	15,573,775 - 15,575,270	UniSTS
Cytogenetic Map	12	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D85760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ120479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ120480	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	OU667100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000001654 ⟹ ENSRNOP00000001654

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	13,805,698 - 13,886,255 (+)	Ensembl
Rnor_6.0 Ensembl	12	15,890,170 - 15,971,212 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093029

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	12	15,890,213 - 15,934,375 (+)	Ensembl

RefSeq Acc Id:

NM_031034 ⟹ NP_112296

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	18,919,629 - 19,000,185 (+)	NCBI
mRatBN7.2	12	13,805,698 - 13,886,255 (+)	NCBI
Rnor_6.0	12	15,890,202 - 15,971,212 (+)	NCBI
Rnor_5.0	12	17,889,996 - 17,970,852 (+)	NCBI
RGSC_v3.4	12	14,275,708 - 14,354,843 (+)	RGD
Celera	12	15,567,135 - 15,646,904 (+)	NCBI

Sequence:

show sequence

CCGGCGGGGCGCGGCCGCGGCCTGAGGGCGGTCATGTCCGGGGTGGTGCGGACCCTCAGCCGCT
GCTTGCTGCCGGCCGAGGCCGGAGCCCGCGAGCGCAGGGCGGGCGCGGCGCGCGACGCGGAACG
CGAGGCCCGACGGCGCAGCCGCGACATCGACGCGCTGCTGGCCCGCGAGCGGCGCGCGGTGCGG
CGGCTGGTCAAGATCTTGCTGCTGGGCGCCGGCGAGAGCGGCAAGTCCACCTTCCTCAAGCAGA
TGCGCATCATCCACGGCCGGGAGTTCGACCAGAAGGCGCTGCTGGAGTTCCGCGACACCATCTT
CGACAACATCCTTAAGGGCTCGAGGGTGCTTGTAGACGCTCGGGACAAGCTTGGCATTCCCTGG
CAGCACTCTGAGAACGAGAAGCACGGGATGTTTCTGATGGCCTTCGAGAACAAGGCAGGGCTGC
CTGTGGAGCCTGCCACCTTCCAGCTCTACGTTCCAGCCCTGAGCGCACTCTGGAGAGACTCCGG
GATCAGGGAAGCCTTCAGCCGCAGAAGCGAGTTCCAGCTGGGTGAGTCAGTGAAGTACTTCCTG
GATAACTTAGACCGGATTGGCCAGCTGAACTACTTCCCCAGTAAGCAAGACATCCTGTTGGCTA
GAAAGGCCACCAAGGGAATCGTGGAGCATGACTTCGTGATAAAGAAAATCCCATTTAAGATGGT
GGATGTGGGCGGCCAGAGGTCGCAGCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACATCG
ATCCTGTTCATGGTGTCCTCAAGCGAGTATGACCAGGTCCTCATGGAGGATAGGCGCACCAACC
GGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTC
CATCATCCTCTTCCTCAACAAGATGGACCTGCTGGTGGAGAAGGTGAAGTCGGTGAGCATTAAG
AAGCACTTCCCAGACTTCAAGGGCGACCCGCACCGGCTGGAGGACGTCCAGCGCTACCTGGTCC
AGTGCTTTGACAGGAAGCGCAGGAACCGCGGCAAGCCTCTGTTCCACCACTTCACCACTGCCAT
AGACACCGAGAACATCCGCTTCGTGTTTCATGCCGTGAAGGACACCATCCTGCAGGAGAACCTG
AAAGATATCATGCTGCAGTGAGACAGCCCCTCTGCCGTCCTCTCGTGGCCTCCGTGGCCTGTGG
CCACATGTCTCTGGTGTGTCTGCCACCTGCATGGACCTGCAGTGGGCATCTCGAAGCCACACCA
TCTAATACCTGGCTCAAGAATGCTGGACTGTCAGCCACACCAGCGAGCTGCGGGCAAGAGGACG
TGGGAGTGTCAGTGATAGCTACTGAATCGGGGACTGAAACTACTGAATCCACGCCATCGCTCTG
GTGTTGATCTGTAAAACCTGGGAACACAGCTTTCTCCCTCCCTACAGAAACTCTTCCTTGCTGA
CACGACTTAACCAAGGTTCAGGTGTGCACAGACACACATGCTCTCATTAATGACAGAAACACAA
CCCCAGCTGGCCTTACAGACAGCTCTTCCCTCTGACTCGCAGGTTCTCACGGAGACACACTAAC
TCGGAAGCTTAGCCTCACGGTAGGCTGTAGAGGGCATGCGCTGCTGCTAAGCTCAGAGTGGCTC
AGCCGCAGTGCCACCTCCCAAAGTGAACACACTGCCTTTAAAATTGTGCCAATACCCTCCGAGT
CCCCACTCTGAGGCACGTCAGGGCCAGCAAAGAAGCCAAGTCAGGTGTCCACACTCCCGACTAG
AGAACAAGGTGGGAGCTGTGAAGCTGCCTCACCGCCCCAGGAGCCACTTACCGTGTCTCCATGC
CCAGTGGGCCGGCCGCAGTGTGGAAGGTGACCTCTGAAGCAGCTCTGGCAGCCTGTGCACACAG
TGGTGCTCTACTTCCCCAGCCTCCACAGCCCATGGCAAAGACACACAACCAAGTGGCCTTGTAG
TTTGCCTTACTTGACAGTTGTGGCATGTAGCATCCCCTGTCCTGGGCTCTGAAAGTGGGCCCAA
GACACTCTGCAGCTGTAGAGCGTCTTCATGTCTTGGCTGCTGGACGGGCCCCAGCCACTGGCCC
TTTAGGAGAAGCCCTGGGGTCTGCACACCGCCCTCACCATTGCCTTCACACAGTGCACTCTGCT
CTCAGAGTGGCTGGCAGGCCGCATTCTGTCGCTGTGCACATAAAGTCAGTCAGCACCCTCCTAG
CCCTGGTCCATGAGGGTGCAGAAGGCTGGGGACATCAGCACAACCTGCTAAGCCTCGCCTCCTT
GGCAGGTGTCACTGTTTTACAATACGTTGCATTCCAGACCTGCCTCTGTCACTGATTGCTTTCT
GGGAGCGGGGGTGTGGCTTATAACTTCCCCAGAGTGTTGTTTTGGTTCACTAACATATCCAAGG
GCCCTGTCTGCAACTGAACTACTCCTGACACTTGATCCCTGTTGCATCCTTGTCTTGGCTCATT
TCAGGCACCAGACACATAGGATTCTTGGAGCAGATGCTAAGCCAGGAGACAGGATGGGGCTGCT
TCTTAGAGCCCTTGTTATGGCAGCGCTCCATCTAGGAAACAGCAGTCAGTCTCTCCTGCTCACT
GTTCTCCCTCTCTGTGCTCAAGTCTGTCAGTGCTCGCTGGCCTCTGGCTCTTCCCTTTGGGGAG
GGAGCGGCTGTTCTGCCTGCTTCACCGAGTCTTCACAAGCTGAGGGGATGAGGCCAGGTTAGTA
CCAGGGACCAGCAACCTTTCAGGGCTCCTTGGGGGTCTCAGGTCCACACACAGTGAGCATCCCT
TGCCAGGTGCCCCATGTATCTGTCAGTGCTGAGACGCCAAACACACAACCTGTTCCCAGCTGCT
GCTGGGGGCCACTGTGACCGAGGAGAGTGTGGGGTTGCCAGGGAGAGCGCTGTCCCTCTGACAG
CCTGACCAGATGATGTAGCTTTGAAAGCCGGCAGCATGTGAGTAGCAAGATGTGACCTTGAGCT
AGCTGAGCAGAACACAGGTGGATGGGCAGAGGCCCCCATCCTGGCGAGCTGAGCCTGGCTGTGT
CCTGTCAGGACGCCCTACTCTGTGACCCTACCCTGTGATCTGTGAAGTGGTGCAGTCGGAAGAC
GAGGCTGGAGTCCTTTACAAGTTTCTACACTAGATTGTAGCCAGGTTTTCTCCCAGGCCTTAGG
CTTTGGTTTACTTTTAATTTTAATTTCACTGTTACCCTTGACTATTGTCCTTTTTGTTGCAGTG
TTGGAGAGGCAGGAGGTATTTGTGCCTCATCTATTACTGCAAAAAAATTAAATAAATGTAACAA
TAAACGTCCTAAAATCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_112296	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAZ23818	(Get FASTA)	NCBI Sequence Viewer
	AAZ23819	(Get FASTA)	NCBI Sequence Viewer
	BAA12867	(Get FASTA)	NCBI Sequence Viewer
	CAG9553618	(Get FASTA)	NCBI Sequence Viewer
	EDL89720	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001654
	ENSRNOP00000001654.5
	ENSRNOP00055015608
	ENSRNOP00060043300
	ENSRNOP00065000155
GenBank Protein	Q63210	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_112296 ⟸ NM_031034

- UniProtKB:

Q63210 (UniProtKB/Swiss-Prot), Q45QM2 (UniProtKB/TrEMBL), Q45QM3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSGVVRTLSRCLLPAEAGARERRAGAARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAG
ESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQHSENEKHGMF
LMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNY
FPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYD
QVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKSVSIKKHFPDFKGDPH
RLEDVQRYLVQCFDRKRRNRGKPLFHHFTTAIDTENIRFVFHAVKDTILQENLKDIMLQ

hide sequence

RefSeq Acc Id:

ENSRNOP00000001654 ⟸ ENSRNOT00000001654

Protein Domains

G-alpha

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q63210-F1-model_v2	AlphaFold	Q63210	1-379	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698452

Promoter ID:

EPDNEW_R8976

Type:

initiation region

Name:

Gna12_1

Description:

G protein subunit alpha 12

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	15,890,093 - 15,890,153	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:71018	AgrOrtholog
BioCyc Gene	G2FUF-19934	BioCyc
Ensembl Genes	ENSRNOG00000001235	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055011424	UniProtKB/Swiss-Prot
	ENSRNOG00060029967	UniProtKB/Swiss-Prot
	ENSRNOG00065000095	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000001654	ENTREZGENE
	ENSRNOT00000001654.8	UniProtKB/Swiss-Prot
	ENSRNOT00055019375	UniProtKB/Swiss-Prot
	ENSRNOT00060052063	UniProtKB/Swiss-Prot
	ENSRNOT00065000156	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.400.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Gprotein_alpha_12/13	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Gprotein_alpha_su	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GproteinA_insert	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:81663	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	81663	ENTREZGENE
PANTHER	GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-12	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10218	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	G-alpha	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gna12	PhenoGen
PRINTS	GPROTEINA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPROTEINA12	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_ALPHA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000001235	RatGTEx
	ENSRNOG00055011424	RatGTEx
	ENSRNOG00060029967	RatGTEx
	ENSRNOG00065000095	RatGTEx
SMART	G_alpha	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47895	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	GNA12_RAT	UniProtKB/Swiss-Prot
	Q45QM2	ENTREZGENE, UniProtKB/TrEMBL
	Q45QM3	ENTREZGENE, UniProtKB/TrEMBL
	Q63210	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-15	Gna12	G protein subunit alpha 12	Gna12	guanine nucleotide binding protein (G protein) alpha 12	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-07-09	Gna12	guanine nucleotide binding protein, alpha 12			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)