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Gene: GRB2 (growth factor receptor bound protein 2) Pan paniscus

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Symbol:

GRB2

Name:

growth factor receptor bound protein 2

RGD ID:

11965721

Description:

ENCODES a protein that exhibits enzyme binding (ortholog); epidermal growth factor receptor binding (ortholog); insulin receptor substrate binding (ortholog); INVOLVED IN actin cytoskeleton organization (inferred); anatomical structure formation involved in morphogenesis (inferred); B cell receptor signaling pathway (inferred); PARTICIPATES IN brain-derived neurotrophic factor signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH breast cancer (ortholog); endometrial carcinoma (ortholog); prostate adenocarcinoma (ortholog); FOUND IN presynapse (ortholog); protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

growth factor receptor-bound protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	91,357,798 - 91,445,600 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	96,180,874 - 96,268,408 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	69,265,307 - 69,352,835 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	74,817,471 - 74,904,022 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	74,817,471 - 74,903,796 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
GRB2	Bonobo	breast cancer	treatment	ISO	GRB2 (Homo sapiens)	9068941		RGD	PMID:17372910 and REF_RGD_ID:13504751
GRB2	Bonobo	endometrial carcinoma	severity	ISO	GRB2 (Homo sapiens)	9068941	Shc-Grb2 complex and protein:increased expression:serum (human)	RGD	PMID:22459351 and REF_RGD_ID:13441552
GRB2	Bonobo	prostate adenocarcinoma		ISO	GRB2 (Homo sapiens)	9068941		RGD	PMID:26103942 and REF_RGD_ID:11056009
GRB2	Bonobo	prostate cancer	treatment	ISO	GRB2 (Homo sapiens)	9068941		RGD	PMID:17372910 and REF_RGD_ID:13504751
GRB2	Bonobo	prostate cancer	disease_progression	ISO	GRB2 (Homo sapiens)	9068941	DNA:amplification and mutation	RGD	PMID:28930697 and REF_RGD_ID:13504750

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
GRB2	Bonobo	actin cytoskeleton organization	acts_upstream_of_or_within	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	anatomical structure formation involved in morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	B cell receptor signaling pathway	involved_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	branching involved in labyrinthine layer morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	cellular response to ionizing radiation	involved_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	endodermal cell differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	epidermal growth factor receptor signaling pathway	involved_in	IEA	UniProtKB:P62993 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	fibroblast growth factor receptor signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	insulin receptor signaling pathway	involved_in	IEA	UniProtKB:P62993 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	insulin-like growth factor receptor signaling pathway	involved_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	myelination	involved_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	natural killer cell mediated cytotoxicity	involved_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	negative regulation of natural killer cell mediated cytotoxicity	involved_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	positive regulation of actin filament polymerization	acts_upstream_of_or_within	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	positive regulation of reactive oxygen species metabolic process	involved_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	receptor internalization	involved_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	regulation of MAPK cascade	acts_upstream_of_or_within	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	Schwann cell development	involved_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	signal transduction in response to DNA damage	involved_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	T cell activation	involved_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
GRB2	Bonobo	cell cortex	is_active_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	cell-cell junction	located_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	centrosome	located_in	IEA	UniProtKB:B0LPF3 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	COP9 signalosome	part_of	IEA	UniProtKB:P62993 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	cytoplasm	located_in	IEA	UniProtKB:P62993 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
GRB2	Bonobo	cytosol	located_in	IEA	ARBA:ARBA00029243	150520179		UniProt	GO_REF:0000117
GRB2	Bonobo	cytosol	located_in	IEA	UniProtKB:B0LPF3 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	endosome	located_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	endosome	located_in	IEA	UniProtKB-KW:KW-0967	150520179		UniProt	GO_REF:0000043
GRB2	Bonobo	endosome	located_in	IEA	UniProtKB-SubCell:SL-0101	150520179		UniProt	GO_REF:0000044
GRB2	Bonobo	Golgi apparatus	located_in	IEA	UniProtKB-SubCell:SL-0132	150520179		UniProt	GO_REF:0000044
GRB2	Bonobo	Golgi apparatus	located_in	IEA	UniProtKB-KW:KW-0333	150520179		UniProt	GO_REF:0000043
GRB2	Bonobo	Grb2-EGFR complex	part_of	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	membrane	located_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	nucleus	located_in	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
GRB2	Bonobo	plasma membrane	located_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	presynapse	is_active_in	ISO	Grb2 (Rattus norvegicus)	9068941	PMID:8022809	SynGO	PMID:8022809 and REF_RGD_ID:405650306
GRB2	Bonobo	protein-containing complex		ISO	Grb2 (Rattus norvegicus)	9068941		RGD	PMID:10973965 and REF_RGD_ID:2303503
GRB2	Bonobo	vesicle membrane	located_in	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
GRB2	Bonobo	enzyme binding		ISO	Cbl (Rattus norvegicus)	9068941		RGD	PMID:9259313 and REF_RGD_ID:11038829
GRB2	Bonobo	ephrin receptor binding	enables	IEA	UniProtKB:P62993 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	epidermal growth factor receptor binding		ISO	Egfr (Rattus norvegicus)	9068941		RGD	PMID:21258655 and REF_RGD_ID:5131481
GRB2	Bonobo	epidermal growth factor receptor binding	enables	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	guanyl-nucleotide exchange factor adaptor activity	enables	IEA	UniProtKB:P62993 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	identical protein binding	enables	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	insulin receptor substrate binding		ISO	Irs1 (Rattus norvegicus)	9068941		RGD	PMID:12891559 and REF_RGD_ID:1299201
GRB2	Bonobo	insulin receptor substrate binding	enables	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	insulin receptor substrate binding		ISO	Irs2 (Rattus norvegicus)	9068941		RGD	PMID:12891559 and REF_RGD_ID:1299201
GRB2	Bonobo	neurotrophin TRKA receptor binding	enables	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	phosphoprotein binding		ISO	Ms4a2 (Rattus norvegicus)	9068941		RGD	PMID:8910399 and REF_RGD_ID:1599952
GRB2	Bonobo	phosphotyrosine residue binding		ISO	Erbb2 (Rattus norvegicus)	9068941		RGD	PMID:9271418 and REF_RGD_ID:1582133
GRB2	Bonobo	phosphotyrosine residue binding	enables	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8C180	9068941	PMID:9182757	IntAct	PMID:9182757
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q15427	9068941	PMID:39251607	IntAct	PMID:39251607
GRB2	Bonobo	protein binding	enables	ISO	PR:Q91XC0	9068941	PMID:10330178	MGI	PMID:10330178
GRB2	Bonobo	protein binding	enables	ISO	PR:Q8BGW0 and PR:Q91YX0	9068941	PMID:22732588	MGI	PMID:22732588
GRB2	Bonobo	protein binding	enables	ISO	PR:Q8BSM5	9068941	PMID:11739737	MGI	PMID:11739737
GRB2	Bonobo	protein binding	enables	ISO	PR:Q8C180	9068941	PMID:9182757	MGI	PMID:9182757
GRB2	Bonobo	protein binding	enables	ISO	PR:Q6P7W2 and PR:Q8R550	9068941	PMID:11152963	MGI	PMID:11152963
GRB2	Bonobo	protein binding	enables	ISO	PR:P46662	9068941	PMID:16405865	MGI	PMID:16405865
GRB2	Bonobo	protein binding	enables	ISO	PR:Q4ACU6	9068941	PMID:15569713	MGI	PMID:15569713
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9QYY0	9068941	PMID:10871282 and PMID:11445578	IntAct	PMID:10871282 and PMID:11445578
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q3UU41	9068941	PMID:21930792 more ...	UniProt	PMID:21930792 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q99JZ7	9068941	PMID:16247031	MGI	PMID:16247031
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O54957	9068941	PMID:21487392 and PMID:24584089	IntAct	PMID:21487392 and PMID:24584089
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9QZE2	9068941	PMID:10744659	UniProt	PMID:10744659
GRB2	Bonobo	protein binding	enables	ISO	PR:Q9QXV8	9068941	PMID:11585837	MGI	PMID:11585837
GRB2	Bonobo	protein binding	enables	ISO	PR:P29351	9068941	PMID:8632004	MGI	PMID:8632004
GRB2	Bonobo	protein binding	enables	ISO	PR:Q9EQR5	9068941	PMID:16249387	MGI	PMID:16249387
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q60749	9068941	PMID:10077576	IntAct	PMID:10077576
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8BGW0-1	9068941	PMID:19805304	IntAct	PMID:19805304
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O43561	9068941	PMID:14722116	UniProt	PMID:14722116
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P35235	9068941	PMID:11684012	IntAct	PMID:11684012
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:B9EKI5 more ...	9068941	PMID:15102471	IntAct	PMID:15102471
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P04925	9068941	PMID:15301538	IntAct	PMID:15301538
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q61234	9068941	PMID:11551227	IntAct	PMID:11551227
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P18052	9068941	PMID:22801373 and PMID:7518772	UniProt	PMID:22801373 and PMID:7518772
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q62245	9068941	PMID:8479540	IntAct	PMID:8479540
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O54957 and UniProtKB:Q62077	9068941	PMID:22561606	IntAct	PMID:22561606
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533	9068941	PMID:10026169 more ...	IntAct	PMID:10026169 more ...
GRB2	Bonobo	protein binding	enables	ISO	PR:Q923U0	9068941	PMID:11711534	MGI	PMID:11711534
GRB2	Bonobo	protein binding	enables	ISO	PR:Q920D3	9068941	PMID:15467741	MGI	PMID:15467741
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P26662-PRO_0000037647	9068941	PMID:10318918	IntAct	PMID:10318918
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 more ...	9068941	PMID:35384245	IntAct	PMID:35384245
GRB2	Bonobo	protein binding	enables	ISO	PR:Q80U87	9068941	PMID:10982817	MGI	PMID:10982817
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q92918 and UniProtKB:Q9Y4K4	9068941	PMID:32707033	IntAct	PMID:32707033
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P98078	9068941	PMID:22323290	IntAct	PMID:22323290
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 and UniProtKB:P29353	9068941	PMID:23178716	IntAct	PMID:23178716
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00750	9068941	PMID:11533253	UniProt	PMID:11533253
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00401 more ...	9068941	PMID:17474147	IntAct	PMID:17474147
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9H706	9068941	PMID:19509291	UniProt	PMID:19509291
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q13480	9068941	PMID:22536782	IntAct	PMID:22536782
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q13094	9068941	PMID:15929943 and PMID:17235283	IntAct	PMID:15929943 and PMID:17235283
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q07666	9068941	PMID:11278465 more ...	IntAct	PMID:11278465 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P29353 and UniProtKB:P35570	9068941	PMID:8491186	UniProt	PMID:8491186
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P50570	9068941	PMID:16696976	IntAct	PMID:16696976
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q05397	9068941	PMID:7597091	IntAct	PMID:7597091
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P18433	9068941	PMID:11923305 more ...	IntAct	PMID:11923305 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P18031 and UniProtKB:P35570	9068941	PMID:10660596	IntAct	PMID:10660596
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P11274	9068941	PMID:10887132 more ...	IntAct	PMID:10887132 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P98078 more ...	9068941	PMID:9569023	IntAct	PMID:9569023
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O92972 and UniProtKB:P27958	9068941	PMID:14993658 and PMID:15784897	IntAct	PMID:14993658 and PMID:15784897
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O43516 more ...	9068941	PMID:21988832	IntAct	PMID:21988832
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 and UniProtKB:P19174	9068941	PMID:9020117	IntAct	PMID:9020117
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P29350 and UniProtKB:Q8N1K5	9068941	PMID:25535246	IntAct	PMID:25535246
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q07889	9068941	PMID:19323566 more ...	IntAct	PMID:19323566 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 and UniProtKB:P22681	9068941	PMID:23799367	IntAct	PMID:23799367
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00401 more ...	9068941	PMID:31980649	IntAct	PMID:31980649
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P22681	9068941	PMID:17094785 more ...	IntAct	PMID:17094785 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00401 more ...	9068941	PMID:27107012	IntAct	PMID:27107012
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q13177 and UniProtKB:Q13444	9068941	PMID:16374509	IntAct	PMID:16374509
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P15498	9068941	PMID:15558030 and PMID:18692475	IntAct	PMID:15558030 and PMID:18692475
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00401 more ...	9068941	PMID:20936779	IntAct	PMID:20936779
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8N1K5	9068941	PMID:21189249 and PMID:28046066	IntAct	PMID:21189249 and PMID:28046066
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O43561-2 and UniProtKB:Q62245	9068941	PMID:16906159	IntAct	PMID:16906159
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P10721 more ...	9068941	PMID:7523381	IntAct	PMID:7523381
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 more ...	9068941	PMID:24658140	IntAct	PMID:24658140
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q05397 more ...	9068941	PMID:21900206	IntAct	PMID:21900206
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P29350	9068941	PMID:10660620	IntAct	PMID:10660620
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:B7ZLH0 more ...	9068941	PMID:25416956	IntAct	PMID:25416956
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O14744 more ...	9068941	PMID:32814053	IntAct	PMID:32814053
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P29353-1 and UniProtKB:Q07889	9068941	PMID:16520382	IntAct	PMID:16520382
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q13444	9068941	PMID:11741929 and PMID:25825872	IntAct	PMID:11741929 and PMID:25825872
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9Y4K4	9068941	PMID:9788432	IntAct	PMID:9788432
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:A0JLT2-2 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 more ...	9068941	PMID:14679214	IntAct	PMID:14679214
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00401 more ...	9068941	PMID:21706016	IntAct	PMID:21706016
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O95630	9068941	PMID:16730941 and PMID:19615732	IntAct	PMID:16730941 and PMID:19615732
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P11274 and UniProtKB:P29353	9068941	PMID:8995379	IntAct	PMID:8995379
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q92918	9068941	PMID:9346925	IntAct	PMID:9346925
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 more ...	9068941	PMID:24189400	IntAct	PMID:24189400
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00401 more ...	9068941	PMID:28514442	IntAct	PMID:28514442
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P15498 and UniProtKB:Q13191	9068941	PMID:29997244	IntAct	PMID:29997244
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 more ...	9068941	PMID:8940013	IntAct	PMID:8940013
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q07889 and UniProtKB:Q07890	9068941	PMID:7629138	IntAct	PMID:7629138
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9H3S7	9068941	PMID:21179510	IntAct	PMID:21179510
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O14744 more ...	9068941	PMID:12577067	IntAct	PMID:12577067
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q12774	9068941	PMID:32203420	IntAct	PMID:32203420
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 and UniProtKB:P04626	9068941	PMID:16273093 and PMID:21278786	IntAct	PMID:16273093 and PMID:21278786
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P10721	9068941	PMID:10377264 and PMID:24728074	IntAct	PMID:10377264 and PMID:24728074
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P29353	9068941	PMID:10356320 more ...	IntAct	PMID:10356320 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9UKW4	9068941	PMID:18654987	IntAct	PMID:18654987
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00459 more ...	9068941	PMID:19380743	IntAct	PMID:19380743
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9UQC2	9068941	PMID:16253990 and PMID:19172738	IntAct	PMID:16253990 and PMID:19172738
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8TBB1	9068941	PMID:29892012	IntAct	PMID:29892012
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 and UniProtKB:Q06124	9068941	PMID:31585087	IntAct	PMID:31585087
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:C8JQR2 more ...	9068941	PMID:12091307	WB	PMID:12091307
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P00533 more ...	9068941	PMID:20473329	IntAct	PMID:20473329
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P35570	9068941	PMID:7504175 and PMID:8491186	IntAct	PMID:7504175 and PMID:8491186
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O95630 more ...	9068941	PMID:31515488	IntAct	PMID:31515488
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O60636 more ...	9068941	PMID:25814554	IntAct	PMID:25814554
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P35235	9068941	PMID:11432792 more ...	IntAct	PMID:11432792 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q6UWF3	9068941	PMID:21930792	UniProt	PMID:21930792
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q5SQ64	9068941	PMID:12852788	IntAct	PMID:12852788
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P18031	9068941	PMID:12023880	IntAct	PMID:12023880 and REF_RGD_ID:8553760
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9Y478	9068941	PMID:18624398	IntAct	PMID:18624398
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P21802	9068941	PMID:22726438	IntAct	PMID:22726438
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O14522	9068941	PMID:21725282	IntAct	PMID:21725282
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9H204	9068941	PMID:15467741 and PMID:16899217	IntAct	PMID:15467741 and PMID:16899217
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8NFH8	9068941	PMID:18647389	IntAct	PMID:18647389
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q52KG5	9068941	PMID:19914172	UniProt	PMID:19914172
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8IWV1	9068941	PMID:12359715	HGNC-UCL	PMID:12359715
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O43597	9068941	PMID:16893902 and PMID:17974561	UniProt	PMID:16893902 and PMID:17974561
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q16236	9068941	PMID:32911434	IntAct	PMID:32911434
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O14672	9068941	PMID:25036101	IntAct	PMID:25036101
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9GZY6	9068941	PMID:14722116	HGNC-UCL	PMID:14722116
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P09917	9068941	PMID:7929073	UniProt	PMID:7929073
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P30530	9068941	PMID:9178760	IntAct	PMID:9178760
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P23469	9068941	PMID:10980613	UniProt	PMID:10980613
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P21575	9068941	PMID:17437541	IntAct	PMID:17437541 and REF_RGD_ID:8554440
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9Y2R2	9068941	PMID:11882361	IntAct	PMID:11882361
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O43561	9068941	PMID:10811803 more ...	IntAct	PMID:10811803 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8WV28	9068941	PMID:16912232 more ...	IntAct	PMID:16912232 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9UQC2-1	9068941	PMID:19523899	IntAct	PMID:19523899
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O75674	9068941	PMID:19798056	IntAct	PMID:19798056
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O43295	9068941	PMID:25819436	IntAct	PMID:25819436
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q02384 and UniProtKB:Q62077	9068941	PMID:15953601	IntAct	PMID:15953601
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P35329	9068941	PMID:10373493 and PMID:11551923	IntAct	PMID:10373493 and PMID:11551923
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P18052 more ...	9068941	PMID:23452850	IntAct	PMID:23452850
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8BGW0	9068941	PMID:19597497 and PMID:19597498	UniProt	PMID:19597497 and PMID:19597498
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P25911 more ...	9068941	PMID:24907343	UniProt	PMID:24907343
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O00401 more ...	9068941	PMID:33961781	IntAct	PMID:33961781
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P18433 and UniProtKB:P29353	9068941	PMID:35271311	IntAct	PMID:35271311
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P35739	9068941	PMID:10748052	IntAct	PMID:10748052 and REF_RGD_ID:8553357
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P18545	9068941	PMID:16357825	IntAct	PMID:16357825 and REF_RGD_ID:8554657
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P18031	9068941	PMID:8940134	IntAct	PMID:8940134 and REF_RGD_ID:1625244
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q5M824	9068941	PMID:11694516	UniProt	PMID:11694516 and REF_RGD_ID:11041061
GRB2	Bonobo	protein binding		ISO	Disc1 (Rattus norvegicus)	9068941		RGD	PMID:17202467 and REF_RGD_ID:5509811
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q05193	9068941	PMID:10206341 and PMID:9922133	IntAct	PMID:10206341 and PMID:9922133
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P42768	9068941	PMID:8892607	BHF-UCL	PMID:8892607
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q7VLE8	9068941	PMID:24902122	IntAct	PMID:24902122
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P54762	9068941	PMID:8798570	IntAct	PMID:8798570
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P35568	9068941	PMID:11694516	UniProt	PMID:11694516 and REF_RGD_ID:11041061
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q6ZWK4	9068941	PMID:25092874	UniProt	PMID:25092874
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q02858	9068941	PMID:10521483	IntAct	PMID:10521483
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:O14939	9068941	PMID:16407827 and PMID:17276458	IntAct	PMID:16407827 and PMID:17276458
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q13191	9068941	PMID:31467278 and PMID:37398436	IntAct	PMID:31467278 and PMID:37398436
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P98078 and UniProtKB:Q62245	9068941	PMID:9569023	IntAct	PMID:9569023
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P98083	9068941	PMID:10748054 more ...	IntAct	PMID:10748054 more ...
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q14457	9068941	PMID:38182563	IntAct	PMID:38182563
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q8N1K5-1	9068941	PMID:23460737	IntAct	PMID:23460737
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:P34152	9068941	PMID:8816475 and PMID:9148935	IntAct	PMID:8816475 and PMID:9148935
GRB2	Bonobo	protein binding	enables	ISO	PR:Q8C180 and PR:Q9QXV9	9068941	PMID:16339969	MGI	PMID:16339969
GRB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q6DN72	9068941	PMID:20933011	UniProt	PMID:20933011
GRB2	Bonobo	protein binding	enables	ISO	PR:P04925	9068941	PMID:11571277	MGI	PMID:11571277
GRB2	Bonobo	protein domain specific binding		ISO	Gab2 (Rattus norvegicus)	9068941		RGD	PMID:10973965 and REF_RGD_ID:2303503
GRB2	Bonobo	protein domain specific binding	enables	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	protein domain specific binding		ISO	Ptpn11 (Rattus norvegicus) and Pik3r1 (Rattus norvegicus)	9068941		RGD	PMID:10973965 and REF_RGD_ID:2303503
GRB2	Bonobo	protein kinase binding	enables	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	protein phosphatase binding	enables	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	protein-containing complex binding		ISO	Grb2 (Rattus norvegicus)	9068941	heterooligomerization	RGD	PMID:15272025 and REF_RGD_ID:1581313
GRB2	Bonobo	protein-macromolecule adaptor activity	enables	IEA	UniProtKB:P62993 more ...	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	SH3 domain binding	enables	IEA	UniProtKB:P62993 and ensembl:ENSP00000339007	150520179		Ensembl	GO_REF:0000107
GRB2	Bonobo	transmembrane receptor protein tyrosine kinase adaptor activity	enables	IEA	UniProtKB:Q60631 and ensembl:ENSMUSP00000021090	150520179		Ensembl	GO_REF:0000107

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
GRB2	Bonobo	brain-derived neurotrophic factor signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		RGD	PMID:23670594 and REF_RGD_ID:11062158
GRB2	Bonobo	epidermal growth factor/neuregulin signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		RGD	PMID:16829981 and REF_RGD_ID:2317988
GRB2	Bonobo	insulin signaling pathway		ISO	Grb2 (Rattus norvegicus)	9068941		RGD	PMID:12891559 and REF_RGD_ID:1299201
GRB2	Bonobo	insulin-like growth factor signaling pathway		ISO	Grb2 (Rattus norvegicus)	9068941		RGD	PMID:15272025 and REF_RGD_ID:1581313
GRB2	Bonobo	interleukin-6 signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		RGD	PMID:22029668 and REF_RGD_ID:5686834
GRB2	Bonobo	scatter factor/hepatocyte growth factor signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		RGD	PMID:14685170 more ...

Imported Annotations - SMPDB

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
GRB2	Bonobo	Fc epsilon receptor mediated signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		SMPDB	SMP:00358
GRB2	Bonobo	insulin signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		SMPDB	SMP:00391

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
GRB2	Bonobo	ephrin - ephrin receptor bidirectional signaling axis		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200052 and PID:200216
GRB2	Bonobo	epidermal growth factor/neuregulin signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200101
GRB2	Bonobo	erythropoietin signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200183
GRB2	Bonobo	fibroblast growth factor signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200220
GRB2	Bonobo	granulocyte-macrophage colony-stimulating factor signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200019
GRB2	Bonobo	insulin signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200014
GRB2	Bonobo	insulin-like growth factor signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200100
GRB2	Bonobo	interleukin-2 signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200098
GRB2	Bonobo	interleukin-3 signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200145
GRB2	Bonobo	interleukin-4 signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200022
GRB2	Bonobo	interleukin-5 signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200107
GRB2	Bonobo	interleukin-6 signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200146
GRB2	Bonobo	platelet-derived growth factor signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200149 and PID:200162
GRB2	Bonobo	transforming growth factor-beta Smad dependent signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200227
GRB2	Bonobo	vascular endothelial growth factor signaling pathway		ISO	GRB2 (Homo sapiens)	9068941		PID	PID:200188

PMID:30032202

GRB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	91,357,798 - 91,445,600 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	96,180,874 - 96,268,408 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	69,265,307 - 69,352,835 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	74,817,471 - 74,904,022 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	74,817,471 - 74,903,796 (-)	Ensembl	panpan1.1		panPan2

GRB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	75,318,076 - 75,405,678 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	75,318,076 - 75,405,709 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	73,314,157 - 73,401,759 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	70,825,752 - 70,913,385 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	70,825,752 - 70,913,329	NCBI
Celera	17	69,906,645 - 69,994,307 (-)	NCBI		Celera
Cytogenetic Map	17	q25.1	NCBI
HuRef	17	68,724,752 - 68,824,731 (-)	NCBI		HuRef
CHM1_1	17	73,378,804 - 73,466,430 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	76,210,297 - 76,297,898 (-)	NCBI		T2T-CHM13v2.0

Grb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	115,534,871 - 115,599,423 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	115,534,871 - 115,599,423 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	115,644,045 - 115,708,597 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	115,644,045 - 115,708,597 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	115,505,444 - 115,569,911 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	115,460,220 - 115,524,687 (-)	NCBI		MGSCv36	mm8
Celera	11	127,412,389 - 127,476,946 (-)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	80.91	NCBI

Grb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	101,380,354 - 101,448,138 (-)	NCBI		GRCr8
mRatBN7.2	10	100,881,404 - 100,949,193 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	100,869,718 - 100,949,309 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	105,941,694 - 106,010,414 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	105,404,767 - 105,473,487 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	100,802,375 - 100,870,155 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	104,193,953 - 104,263,071 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	104,193,955 - 104,263,071 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	104,019,823 - 104,087,251 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	10	104,735,560 - 104,738,091 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	105,722,014 - 105,818,649 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	105,737,088 - 105,833,269 (-)	NCBI
Celera	10	99,455,840 - 99,524,352 (-)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

Grb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955553	2,186,590 - 2,259,456 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955553	2,186,590 - 2,258,964 (-)	NCBI	ChiLan1.0	ChiLan1.0

GRB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	5,108,128 - 5,182,091 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	5,117,164 - 5,180,296 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	5,787,497 - 5,861,309 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	5,778,347 - 5,852,258 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	5,778,263 - 5,852,254 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	5,817,381 - 5,891,089 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	5,927,508 - 6,001,301 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	5,988,590 - 6,061,075 (+)	NCBI		UU_Cfam_GSD_1.0

Grb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	5,750,590 - 5,819,199 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936594	592,740 - 661,369 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936594	592,760 - 661,369 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GRB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	5,940,647 - 6,010,835 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	5,940,723 - 6,009,095 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	5,860,464 - 5,928,885 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GRB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	46,264,818 - 46,346,426 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	46,264,825 - 46,347,156 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	17,032,097 - 17,115,635 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Grb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	5,143,141 - 5,219,244 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	5,143,239 - 5,219,136 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_003813290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000032495 ⟹ ENSPPAP00000009849

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	74,817,471 - 74,903,796 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032507 ⟹ ENSPPAP00000009861

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	74,819,771 - 74,893,743 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032509 ⟹ ENSPPAP00000009862

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	17	74,819,785 - 74,893,743 (-)	Ensembl

RefSeq Acc Id:

XM_003813290 ⟹ XP_003813338

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	19	91,357,798 - 91,445,600 (-)	NCBI
NHGRI_mPanPan1	17	96,180,874 - 96,268,408 (-)	NCBI
Mhudiblu_PPA_v0	17	69,265,307 - 69,352,835 (-)	NCBI
PanPan1.1	17	74,817,471 - 74,904,022 (-)	NCBI

Sequence:

show sequence

GTGGAGAAGTTCTCGCGGGACACCGACGGGGAGCGGAAGCCAGGAGGCATTGCTGCTTCGGCGACCGGGCGGCGGCGGCGGCGGCGGCTGTGGCAGAGCCTGTGCCTGTGGCGGTGACGGCGGCGGGA
GCAAGCGCTGCCCTCGCAGAGCAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGTGGAGGGGCGGGCCGGACGCTGAGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCG
AGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGA
CTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGTTTTGAACGAAGAATGTGATCAGAACTGGTACAAGGCAGAGCTTAATGGAAAAGACGGCTTCATTCCCAAGA
ACTACATAGAAATGAAACCACATCCGTGGTTTTTTGGCAAAATCCCCAGAGCCAAGGCAGAAGAAATGCTTAGCAAACAGCGGCACGATGGGGCCTTTCTTATCCGAGAGAGTGAGAGCGCTCCTGGG
GACTTCTCCCTCTCTGTCAAGTTTGGAAACGATGTGCAGCACTTCAAGGTGCTCCGAGATGGAGCCGGGAAGTACTTCCTCTGGGTGGTGAAGTTCAATTCTTTGAATGAGCTGGTGGATTATCACAG
ATCTACATCTGTCTCCAGAAACCAGCAGATATTCCTGCGGGACATAGAACAGGTGCCACAGCAGCCGACATACGTCCAGGCCCTCTTTGACTTTGATCCCCAGGAGGATGGAGAGCTGGGCTTCCGCC
GGGGAGATTTTATCCATGTCATGGATAACTCAGACCCCAACTGGTGGAAAGGAGCTTGCCACGGGCAGACCGGCATGTTTCCCCGCAATTATGTCACCCCCGTGAACCGGAACGTCTAAGAGTCAAGA
AGCAATTATTTAAAGAAAGTGAAAAATGTAAAACACATACAAAAGAATTAAACCCACAAGCTGCCTCTGACAGCAGCCTGTGAGGGAGTGCAGAACACCTGGCCGGGTCACCCTGTGACCCTCTCACT
TTGGTTGGAACTTTAGGGGGTGGGAGGGGGCGTTGGATTTAAAAATGCCAAAACTTACCTATAAATTAAGAAGAGTTTTTATTACAAATTTTCACTGCTGCTCCTCTTTCCCCTCCTTTGTCTTTTTT
TTCATCCTTTTTTCTCTTCTGTCCATCAGTGCATGACGTTTAAGGCCACGTATAGTCCTAGCTGACGCCAATAATAAAAAACAAGAAACCAAGTGGGCTGGTATTCTCTCTATGCAAAATGTCTGTTT
TAGTTGGAATGACTGAAAGAAGAACAGCTGTTCCTGTGTTCTTCGTATATACACACAAAAAGGAGCGGGCAGGGCCGCTCGACGCCTTTGCTGTTTAGCTTCCTCCAGAGGAGGGGACTTGCAGGAAT
CTGCCTTCCAGCCCAGACCCCCAGTGTATTTTGTCCAAGTTCGCAGTAGAGTGGGGTAGAAGGAAAGCATGTCTCTGCTTCCATGGCTTCCTGAGAAAGCCCACCTGGGCCGGGCGCGGTGGCTCACG
CCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACAAGGTCAGGAGTTCGAGACCAACCTAGCCAACATGGTGAAACCCCGTCTCTACTAAAAATAAAAAATTAGCCGCGTGTGGTGGCA
CACGCCTGTAGTCCCAGCTACTCGGGAGCCTGAGGCAGGAAGAATCGCTTGAACCCTGGGAAGGTGGAGGTTGAGTGAGCGTCGGGGACCGTGCCATTGTACCTCCTACGCCGTGGGGTGACAGAGCG
AGATTCCGTCTCAAAGAAAAAAAAAAAAAAAGCCCACCTGAAAGCCTGTCTCTTTCCACTTTGTTGGCCCTTCCAGTGGGATTATCGAGCATGTTGTTTTTCATAGTGCCTTTTTCCTTATTTCAAGG
GTTGCTTCTGAGTGGTGTTTTTTTTTAATTTGTTTTGTTTTAAAATAAGTTAAAGACAGTCCAGAGCTTCTCAGCCAATTTGTCTCCTACTCTGTGTAAATATTTTTCCCTCCGGGCAGGGGAGCCAG
GGTAGAGCAAAGGAGACAAGCAGGAGTGGAAGGTGAGGCGTTCTCCTGCTTGTACTAAGCCAGGAGGCTTTAAGCTCCAGCTTTAAGGGTTGTGAGCCCCTTGGGGGTTCAGGGAACTGCTTGCCCAG
GGTGCAGTGTGAGTGTGATGGGCCACCGGGGCAAGAGGGAAGGTGACCGCCCAGCTCTCCCACATCCCACTGGATCTGGCTTACAGGGGGGTCGGAAGCCTGTCCTCACCGTCTCGGGGGTTGTGGCC
CCCGCCCCCTCCCTATATGCACCCCTGGAACCAGCAAGTCCCAGTCAAGGAGAGCGGAGGAGGAAGTCGTGGGAATGCAGCCTCCAGTTGTAGCAGGTTTCACTGTATTCCTATGCTGGGGTACACAG
TGAGAGTACTCACTTTTCACTTGTCTTGCTCTTAGATTGGGCCATGGCTTTCATCCTGTGTCCCCTGACCTGTCCAGGTGAGTGTGAGGGCAGCACTGGGAAGCTGGAGTGCTGCTTGTGCCTCCCTT
CCCAGTGGGCTGTGTTGACTGCTGCTCCCCACCCCTACCGATGGTCCCAGGAAGCAGGGAGAGTTGGGAAAGGCAAGATTGGAAAGACAGGAAGACCAAGGCCTCGGCAGAACTCTGTCTTCTCTCCA
CCTCTGGTCCCCTGTGGTGATGTGCCTGTAATCTTTTTCTCCACCCAAACCCCTTACCACGACAAAAACAAGACTGCCTCCCTCTCTTCTGGGAGCTGGTGACAGCCTTGGGCCTTTCAGTCCCAAAG
CGGCCAATGGGAGTCTCCCTCCGACTCCAGATATGAACAGGGCCCAGGCCTGGAGCGTTTGCTGTGCCAGGAGGCGGCAGCTCTTCTGGGCAGAGCCTGTCCCCGCCTTCCCTCACTCTTCCTCATCC
TGCTTCTCTTTTCCTCGCAGATGATAAAAGGAATCTGGCATTCTACACCTGGACCATTTGATTGTTTTATTTTGGAATTGGTGTATATCATGAAGCCTTGCTGAACTAAGTTTTGTGTGTATATATTT
AAAAAAAAAAATCAGTGTTTAAATAAAGACCTATGTACTTAATCCTTTAACTCTGCGGATAGCATTTGGTAGGTAGTGATTAACTGTGAATAATAAATATACAATGAATTCTTCA

hide sequence


Protein RefSeqs	XP_003813338	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000009849.1
	ENSPPAP00000009861.1
	ENSPPAP00000009862.1

RefSeq Acc Id:

XP_003813338 ⟸ XM_003813290

- UniProtKB:

A0A2R9A3I9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSL
NELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV

hide sequence

Ensembl Acc Id:

ENSPPAP00000009849 ⟸ ENSPPAT00000032495

Ensembl Acc Id:

ENSPPAP00000009862 ⟸ ENSPPAT00000032509

Ensembl Acc Id:

ENSPPAP00000009861 ⟸ ENSPPAT00000032507

Protein Domains

SH2 SH3

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000028137	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000032495.1	UniProtKB/TrEMBL
	ENSPPAT00000032507.1	UniProtKB/TrEMBL
	ENSPPAT00000032509.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.505.10	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
InterPro	Grb2-like	UniProtKB/TrEMBL
	GRB2_C_SH3	UniProtKB/TrEMBL
	GRB2_N_SH3	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SH2_dom_sf	UniProtKB/TrEMBL
	SH3-like_dom_sf	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
KEGG Report	pps:100993451	UniProtKB/TrEMBL
NCBI Gene	GRB2	ENTREZGENE
PANTHER	PTHR46037	UniProtKB/TrEMBL
Pfam	SH2	UniProtKB/TrEMBL
	SH3_1	UniProtKB/TrEMBL
PRINTS	P67PHOX	UniProtKB/TrEMBL
	SH2DOMAIN	UniProtKB/TrEMBL
	SH3DOMAIN	UniProtKB/TrEMBL
PROSITE	SH2	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
SMART	SH2	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50044	UniProtKB/TrEMBL
	SSF55550	UniProtKB/TrEMBL
UniProt	A0A2R8ZY28_PANPA	UniProtKB/TrEMBL
	A0A2R8ZZ46_PANPA	UniProtKB/TrEMBL
	A0A2R9A3I9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)