STX1A (syntaxin 1A) - Rat Genome Database

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Gene: STX1A (syntaxin 1A) Pan paniscus
Analyze
Symbol: STX1A
Name: syntaxin 1A
RGD ID: 11830776
Description: ENCODES a protein that exhibits ATP-dependent protein binding (ortholog); calcium-dependent protein binding (ortholog); myosin binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); modulation of excitatory postsynaptic potential (ortholog); positive regulation of calcium ion-dependent exocytosis (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); FOUND IN acrosomal vesicle (ortholog); actomyosin (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: syntaxin-1A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2691,180,408 - 91,200,924 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17139,445,039 - 139,465,555 (+)NCBINHGRI_mPanPan1
PanPan1.1780,852,495 - 80,871,635 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl780,852,495 - 80,862,255 (-)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STX1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2691,180,408 - 91,200,924 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17139,445,039 - 139,465,555 (+)NCBINHGRI_mPanPan1
PanPan1.1780,852,495 - 80,871,635 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl780,852,495 - 80,862,255 (-)Ensemblpanpan1.1panPan2
STX1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38773,699,210 - 73,719,669 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl773,699,206 - 73,719,672 (-)EnsemblGRCh38hg38GRCh38
GRCh37773,113,540 - 73,133,999 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,751,476 - 72,771,924 (-)NCBINCBI36Build 36hg18NCBI36
Build 34772,558,190 - 72,578,613NCBI
Celera768,591,739 - 68,612,223 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef768,995,950 - 69,016,432 (-)NCBIHuRef
CHM1_1773,259,272 - 73,279,754 (-)NCBICHM1_1
T2T-CHM13v2.0774,900,126 - 74,920,586 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2772,446,607 - 72,467,089 (-)NCBI
Stx1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,051,473 - 135,079,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5135,052,336 - 135,079,954 (+)EnsemblGRCm39 Ensembl
GRCm385135,023,482 - 135,051,100 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,023,482 - 135,051,100 (+)EnsemblGRCm38mm10GRCm38
MGSCv375135,499,442 - 135,526,969 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365135,308,199 - 135,335,726 (+)NCBIMGSCv36mm8
Celera5132,033,901 - 132,061,428 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map574.95NCBI
Stx1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,278,517 - 27,306,547 (-)NCBIGRCr8
mRatBN7.21221,641,971 - 21,670,022 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,641,969 - 21,669,930 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1222,782,666 - 22,810,512 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,394,983 - 23,422,828 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01222,463,210 - 22,491,166 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,682,050 - 24,710,002 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,682,041 - 24,710,019 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,682,320 - 26,710,272 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,737,112 - 22,765,064 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1223,405,260 - 23,432,900 (-)NCBICelera
Cytogenetic Map12q12NCBI
Stx1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,030,226 - 14,046,456 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545614,030,233 - 14,046,456 (+)NCBIChiLan1.0ChiLan1.0
STX1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,574,616 - 6,583,002 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,574,631 - 6,581,833 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha68,263,577 - 8,280,400 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.066,381,214 - 6,398,029 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl66,381,225 - 6,398,461 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.166,370,709 - 6,387,529 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.066,318,461 - 6,335,266 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,482,166 - 6,498,979 (+)NCBIUU_Cfam_GSD_1.0
Stx1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344131,118,736 - 131,127,007 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365432,909,552 - 2,918,770 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365432,909,560 - 2,918,175 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STX1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,347,495 - 9,367,948 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl289,347,532 - 9,368,585 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660707,135,019 - 7,155,486 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stx1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474014,104,050 - 14,120,133 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474014,104,033 - 14,120,133 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000065530   ⟹   ENSPPAP00000042600
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl780,852,495 - 80,862,255 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065533   ⟹   ENSPPAP00000042603
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl780,853,703 - 80,862,255 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065535   ⟹   ENSPPAP00000042605
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl780,854,178 - 80,862,255 (-)Ensembl
RefSeq Acc Id: XM_034951424   ⟹   XP_034807315
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2691,180,408 - 91,200,924 (+)NCBI
NHGRI_mPanPan17139,445,039 - 139,465,555 (+)NCBI
RefSeq Acc Id: XM_034951425   ⟹   XP_034807316
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2691,180,408 - 91,199,397 (+)NCBI
NHGRI_mPanPan17139,445,039 - 139,464,028 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034807315 (Get FASTA)   NCBI Sequence Viewer  
  XP_034807316 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000042600.1
  ENSPPAP00000042603.1
  ENSPPAP00000042605.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000042600   ⟸   ENSPPAT00000065530
RefSeq Acc Id: ENSPPAP00000042605   ⟸   ENSPPAT00000065535
RefSeq Acc Id: ENSPPAP00000042603   ⟸   ENSPPAT00000065533
RefSeq Acc Id: XP_034807315   ⟸   XM_034951424
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CKT4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034807316   ⟸   XM_034951425
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CKT9 (UniProtKB/TrEMBL)
Protein Domains
Syntaxin N-terminal   t-SNARE coiled-coil homology


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043854 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000065530.1 UniProtKB/TrEMBL
  ENSPPAT00000065533.1 UniProtKB/TrEMBL
  ENSPPAT00000065535.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.110 UniProtKB/TrEMBL
  1.20.58.70 UniProtKB/TrEMBL
InterPro SNARE UniProtKB/TrEMBL
  Syntaxin UniProtKB/TrEMBL
  Syntaxin/epimorphin_CS UniProtKB/TrEMBL
  Syntaxin_N UniProtKB/TrEMBL
  T_SNARE_dom UniProtKB/TrEMBL
NCBI Gene STX1A ENTREZGENE
PANTHER PTHR19957 UniProtKB/TrEMBL
  PTHR19957:SF84 UniProtKB/TrEMBL
Pfam SNARE UniProtKB/TrEMBL
  Syntaxin UniProtKB/TrEMBL
PROSITE SYNTAXIN UniProtKB/TrEMBL
  T_SNARE UniProtKB/TrEMBL
SMART SynN UniProtKB/TrEMBL
  t_SNARE UniProtKB/TrEMBL
Superfamily-SCOP SSF47661 UniProtKB/TrEMBL
UniProt A0A2R9CKT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CKT9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CN76_PANPA UniProtKB/TrEMBL