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Gene: STX1A (syntaxin 1A) Homo sapiens
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Symbol: STX1A
Name: syntaxin 1A
Description: Exhibits chloride channel inhibitor activity; identical protein binding activity; and kinase binding activity. Involved in protein sumoylation; synaptic vesicle endocytosis; and synaptic vesicle exocytosis. Localizes to the SNARE complex; neuron projection; and plasma membrane. Predicted to colocalize with the voltage-gated potassium channel complex. Implicated in Creutzfeldt-Jakob disease and Hirschsprung's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HPC-1; neuron-specific antigen HPC-1; P35-1; STX1; SYN1A; syntaxin 1A (brain); syntaxin-1A
Orthologs:
Mus musculus (house mouse) : Stx1a (syntaxin 1A (brain))  MGI  Alliance
Rattus norvegicus (Norway rat) : Stx1a (syntaxin 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stx1a (syntaxin 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : STX1A (syntaxin 1A)
Canis lupus familiaris (dog) : STX1A (syntaxin 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stx1a (syntaxin 1A)
Sus scrofa (pig) : STX1A (syntaxin 1A)
Chlorocebus sabaeus (green monkey) : STX1A (syntaxin 1A)
Heterocephalus glaber (naked mole-rat) : Stx1a (syntaxin 1A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl773,699,206 - 73,719,672 (-)Ensembl
GRCh38773,699,210 - 73,719,673 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,113,535 - 73,134,032 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,751,476 - 72,771,924 (-)NCBINCBI36hg18NCBI36
Build 34772,558,190 - 72,578,613NCBI
Celera768,591,739 - 68,612,223 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef768,995,950 - 69,016,432 (-)NCBIHuRef
CHM1_1773,259,272 - 73,279,754 (-)NCBICHM1_1
CRA_TCAGchr7v2772,446,607 - 72,467,089 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on STX1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69485
Created: 2001-11-27
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.