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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:type II interferon signaling pathway
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Accession:PW:0000896 term browser browse the term
Definition:Type II interferon, of which there is only one in humans, binds to distinct receptors that activate the Jak-Stat signaling pathway. It is known as interferon gamma signaling.
Synonyms:related_synonym: interferon gamma signaling;   type II interferon-mediated signaling pathway


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type II interferon signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200129
G CALM1 calmodulin 1 ISO PID PID:200129 NCBI chr 7:112,160,823...112,171,754
Ensembl chr 7:112,160,806...112,171,744 		JBrowse link
G CALM2 calmodulin 2 ISO PID PID:200129 NCBI chr 3:93,371,765...93,386,378
Ensembl chr 3:93,372,045...93,386,218 		JBrowse link
G CALM3 calmodulin 3 ISO PID PID:200129 NCBI chr 6:52,506,979...52,516,704
Ensembl chr 6:52,506,674...52,516,703 		JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO PID PID:200129 NCBI chr 2:151,248,356...151,353,907
Ensembl chr 2:151,248,358...151,308,706 		JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO PID PID:200129 NCBI chr18:50,862,225...50,956,263
Ensembl chr18:50,861,466...50,956,225 		JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO PID PID:200129 NCBI chr 8:108,916,019...109,221,317
Ensembl chr 8:108,915,572...109,222,905 		JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma ISO PID PID:200129 NCBI chr14:76,535,095...76,632,381
Ensembl chr14:76,535,096...76,593,108 		JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase ISO PID PID:200129 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328 		JBrowse link
G CBL Cbl proto-oncogene ISO PID PID:200129 NCBI chr 9:46,416,937...46,512,855
Ensembl chr 9:46,416,938...46,512,834 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO PID PID:200129 NCBI chr17:51,722,633...51,723,673
Ensembl chr17:51,722,426...51,724,305 		JBrowse link
G CREBBP CREB binding protein ISO PID PID:200129 NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,224 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO PID PID:200129 NCBI chr14:50,528,950...50,558,664
Ensembl chr14:50,528,955...50,558,662 		JBrowse link
G DAPK1 death associated protein kinase 1 ISO PID PID:200129 NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,648...27,954,350 		JBrowse link
G EP300 E1A binding protein p300 ISO PID PID:200129 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760 		JBrowse link
G IFNG interferon gamma ISO PID PID:200129 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO PID PID:200129 NCBI chr 1:27,037,151...27,061,095
Ensembl chr 1:27,037,165...27,061,093 		JBrowse link
G IRF1 interferon regulatory factor 1 ISO PID PID:200129 NCBI chr 2:134,776,122...134,783,646
Ensembl chr 2:134,776,129...134,783,801 		JBrowse link
G IRF9 interferon regulatory factor 9 ISO PID PID:200129 NCBI chr 7:75,133,800...75,139,641
Ensembl chr 7:75,126,622...75,139,640 		JBrowse link
G JAK1 Janus kinase 1 ISO PID PID:200129 NCBI chr 6:147,320,288...147,567,188
Ensembl chr 6:147,429,056...147,567,182 		JBrowse link
G JAK2 Janus kinase 2 ISO PID PID:200129 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148 		JBrowse link
G LOC110258578 interleukin-1 beta-like ISO PID PID:200129
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO PID PID:200129 NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200129 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987 		JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 ISO PID PID:200129 NCBI chr 2:6,640,061...6,657,717
Ensembl chr 2:6,640,056...6,657,713 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200129 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO PID PID:200129 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO PID PID:200129 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 ISO PID PID:200129 NCBI chr 1:165,957,114...166,087,242
Ensembl chr 1:165,957,132...166,087,239 		JBrowse link
G PIAS4 protein inhibitor of activated STAT 4 ISO PID PID:200129 NCBI chr 2:74,702,915...74,729,792
Ensembl chr 2:74,702,945...74,729,775 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200129 NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200129 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609 		JBrowse link
G PRKCD protein kinase C delta ISO PID PID:200129 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G PTGES2 prostaglandin E synthase 2 ISO PID PID:200129 NCBI chr 1:268,585,725...268,591,356
Ensembl chr 1:268,583,439...268,590,855 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO PID PID:200129 NCBI chr14:39,202,165...39,292,041
Ensembl chr14:39,202,169...39,292,003 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO PID PID:200129 NCBI chr 4:108,675,537...108,750,952
Ensembl chr 4:108,676,685...108,743,368 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family ISO PID PID:200129 NCBI chr 5:32,910,181...32,961,972
Ensembl chr 5:32,910,259...32,964,870 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO PID PID:200129 NCBI chr 1:271,494,243...271,624,609
Ensembl chr 1:271,494,248...271,600,920 		JBrowse link
G SMAD7 SMAD family member 7 ISO PID PID:200129 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,514,267...98,542,382 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO PID PID:200129 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO PID PID:200129 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO PID PID:200129 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    signaling pathway 1931
      signaling pathway pertinent to immunity 417
        cytokine mediated signaling pathway 333
          interferon mediated signaling pathway 43
            type II interferon signaling pathway 42
paths to the root