CAMK2A (calcium/calmodulin dependent protein kinase II alpha) - Rat Genome Database

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Gene: CAMK2A (calcium/calmodulin dependent protein kinase II alpha) Sus scrofa
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Symbol: CAMK2A
Name: calcium/calmodulin dependent protein kinase II alpha
RGD ID: 13856610
Description: ENCODES a protein that exhibits calcium-dependent protein serine/threonine kinase activity (ortholog); calmodulin-dependent protein kinase activity (ortholog); glutamate receptor binding (ortholog); INVOLVED IN calcium ion transport (ortholog); calmodulin dependent kinase signaling pathway (ortholog); dendrite morphogenesis (ortholog); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; fibroblast growth factor signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); autosomal dominant mental retardation 53 (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN axon (ortholog); cytosol (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcium/calmodulin-dependent protein kinase type II subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2151,248,356 - 151,308,658 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12151,248,356 - 151,353,907 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22158,335,771 - 158,396,987 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
CAMK2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2151,248,356 - 151,308,658 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12151,248,356 - 151,353,907 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22158,335,771 - 158,396,987 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CAMK2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385150,219,491 - 150,290,130 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl5150,219,491 - 150,290,093 (-)EnsemblGRCh38hg38GRCh38
GRCh375149,599,054 - 149,669,693 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365149,579,248 - 149,649,529 (-)NCBINCBI36hg18NCBI36
Build 345149,579,247 - 149,649,529NCBI
Celera5145,680,447 - 145,750,799 (-)NCBI
Cytogenetic Map5q32NCBI
HuRef5144,747,170 - 144,817,356 (-)NCBIHuRef
CHM1_15149,031,647 - 149,101,993 (-)NCBICHM1_1
T2T-CHM13v2.05150,756,093 - 150,826,669 (-)NCBI
Camk2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391861,058,379 - 61,121,224 (+)NCBIGRCm39mm39
GRCm39 Ensembl1861,058,690 - 61,121,224 (+)Ensembl
GRCm381860,925,307 - 60,988,152 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1860,925,618 - 60,988,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv371861,085,286 - 61,147,806 (+)NCBIGRCm37mm9NCBIm37
MGSCv361861,051,001 - 61,113,513 (+)NCBImm8
Celera1862,212,530 - 62,274,768 (+)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.41NCBI
Camk2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21854,378,642 - 54,441,120 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1854,378,784 - 54,438,994 (+)Ensembl
Rnor_6.01856,193,978 - 56,295,869 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1856,193,978 - 56,295,869 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01855,428,487 - 55,463,016 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01855,514,559 - 55,529,045 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41856,879,247 - 56,948,537 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11856,951,478 - 57,020,769 (+)NCBI
Celera1852,533,226 - 52,592,130 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Camk2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554154,247,014 - 4,307,458 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554154,247,307 - 4,307,402 (+)NCBIChiLan1.0ChiLan1.0
CAMK2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15151,649,062 - 151,719,373 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5151,649,062 - 151,719,373 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05145,644,164 - 145,714,143 (-)NCBIMhudiblu_PPA_v0panPan3
CAMK2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1458,800,818 - 58,865,830 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl458,800,813 - 58,865,830 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha458,567,052 - 58,631,982 (+)NCBI
ROS_Cfam_1.0459,281,664 - 59,346,612 (+)NCBI
ROS_Cfam_1.0 Ensembl459,281,703 - 59,346,615 (+)Ensembl
UMICH_Zoey_3.1459,070,398 - 59,135,346 (+)NCBI
UNSW_CanFamBas_1.0459,184,686 - 59,249,804 (+)NCBI
UU_Cfam_GSD_1.0459,715,947 - 59,780,872 (+)NCBI
Camk2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213143,064,159 - 143,126,577 (+)NCBI
SpeTri2.0NW_0049365044,636,863 - 4,700,887 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAMK2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12352,829,438 - 52,899,428 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2352,829,350 - 52,899,375 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603424,817,181 - 24,887,318 (+)NCBIVero_WHO_p1.0
Camk2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247749,526,323 - 9,585,649 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247749,526,323 - 9,585,647 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system reproductive system respiratory system
High
Medium 2 2 11
Low 2 1 1 10
Below cutoff 6 2 2 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015790   ⟹   ENSSSCP00000015374
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2151,248,362 - 151,308,658 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000027746   ⟹   ENSSSCP00000025639
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2151,248,356 - 151,308,630 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000052397   ⟹   ENSSSCP00000053235
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2151,248,356 - 151,270,722 (-)Ensembl
RefSeq Acc Id: XM_003124102   ⟹   XP_003124150
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,314,691 - 151,353,825 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003354356   ⟹   XP_003354404
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,248,356 - 151,308,667 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005652961   ⟹   XP_005653018
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,251,527 - 151,308,668 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005652962   ⟹   XP_005653019
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,248,362 - 151,308,668 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085017   ⟹   XP_020940676
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,248,356 - 151,353,907 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085018   ⟹   XP_020940677
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,248,362 - 151,353,907 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085019   ⟹   XP_020940678
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,251,527 - 151,308,668 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085020   ⟹   XP_020940679
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,248,362 - 151,287,313 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085021   ⟹   XP_020940680
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12151,248,362 - 151,287,324 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020940676   ⟸   XM_021085017
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003354404   ⟸   XM_003354356
- Peptide Label: isoform X5
- UniProtKB: I3LNG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020940677   ⟸   XM_021085018
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005653019   ⟸   XM_005652962
- Peptide Label: isoform X3
- UniProtKB: F1RL74 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020940680   ⟸   XM_021085021
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_020940679   ⟸   XM_021085020
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_005653018   ⟸   XM_005652961
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_020940678   ⟸   XM_021085019
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_003124150   ⟸   XM_003124102
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: ENSSSCP00000015374   ⟸   ENSSSCT00000015790
RefSeq Acc Id: ENSSSCP00000053235   ⟸   ENSSSCT00000052397
RefSeq Acc Id: ENSSSCP00000025639   ⟸   ENSSSCT00000027746
Protein Domains
CaMKII_AD   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014443 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00015002158 UniProtKB/TrEMBL
  ENSSSCG00025067157 UniProtKB/TrEMBL
  ENSSSCG00030025423 UniProtKB/TrEMBL
  ENSSSCG00035030132 UniProtKB/TrEMBL
  ENSSSCG00040009718 UniProtKB/TrEMBL
  ENSSSCG00045027214 UniProtKB/TrEMBL
  ENSSSCG00050006978 UniProtKB/TrEMBL
  ENSSSCG00055006782 UniProtKB/TrEMBL
  ENSSSCG00060063003 UniProtKB/TrEMBL
  ENSSSCG00065037240 UniProtKB/TrEMBL
  ENSSSCG00070007467 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000015374 UniProtKB/TrEMBL
  ENSSSCP00000025639 UniProtKB/TrEMBL
  ENSSSCP00000053235 UniProtKB/TrEMBL
  ENSSSCP00015001105 UniProtKB/TrEMBL
  ENSSSCP00015001113 UniProtKB/TrEMBL
  ENSSSCP00015001180 UniProtKB/TrEMBL
  ENSSSCP00025040960 UniProtKB/TrEMBL
  ENSSSCP00025041247 UniProtKB/TrEMBL
  ENSSSCP00030016167 UniProtKB/TrEMBL
  ENSSSCP00030016185 UniProtKB/TrEMBL
  ENSSSCP00035015978 UniProtKB/TrEMBL
  ENSSSCP00035015979 UniProtKB/TrEMBL
  ENSSSCP00035015980 UniProtKB/TrEMBL
  ENSSSCP00035015985 UniProtKB/TrEMBL
  ENSSSCP00035015988 UniProtKB/TrEMBL
  ENSSSCP00035015991 UniProtKB/TrEMBL
  ENSSSCP00035015994 UniProtKB/TrEMBL
  ENSSSCP00040005113 UniProtKB/TrEMBL
  ENSSSCP00040005145 UniProtKB/TrEMBL
  ENSSSCP00040005246 UniProtKB/TrEMBL
  ENSSSCP00040005284 UniProtKB/TrEMBL
  ENSSSCP00045032150 UniProtKB/TrEMBL
  ENSSSCP00045032338 UniProtKB/TrEMBL
  ENSSSCP00045032481 UniProtKB/TrEMBL
  ENSSSCP00050004083 UniProtKB/TrEMBL
  ENSSSCP00050004088 UniProtKB/TrEMBL
  ENSSSCP00050004091 UniProtKB/TrEMBL
  ENSSSCP00050004107 UniProtKB/TrEMBL
  ENSSSCP00050004113 UniProtKB/TrEMBL
  ENSSSCP00050004121 UniProtKB/TrEMBL
  ENSSSCP00050004126 UniProtKB/TrEMBL
  ENSSSCP00055011598 UniProtKB/TrEMBL
  ENSSSCP00055011666 UniProtKB/TrEMBL
  ENSSSCP00055011749 UniProtKB/TrEMBL
  ENSSSCP00055011851 UniProtKB/TrEMBL
  ENSSSCP00055011941 UniProtKB/TrEMBL
  ENSSSCP00060037610 UniProtKB/TrEMBL
  ENSSSCP00060037622 UniProtKB/TrEMBL
  ENSSSCP00060037685 UniProtKB/TrEMBL
  ENSSSCP00060037718 UniProtKB/TrEMBL
  ENSSSCP00065022068 UniProtKB/TrEMBL
  ENSSSCP00065022071 UniProtKB/TrEMBL
  ENSSSCP00065022099 UniProtKB/TrEMBL
  ENSSSCP00070011908 UniProtKB/TrEMBL
  ENSSSCP00070011926 UniProtKB/TrEMBL
  ENSSSCP00070011949 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015790 UniProtKB/TrEMBL
  ENSSSCT00000027746 UniProtKB/TrEMBL
  ENSSSCT00000052397 UniProtKB/TrEMBL
  ENSSSCT00015003304 UniProtKB/TrEMBL
  ENSSSCT00015003331 UniProtKB/TrEMBL
  ENSSSCT00015003473 UniProtKB/TrEMBL
  ENSSSCT00025093361 UniProtKB/TrEMBL
  ENSSSCT00025093981 UniProtKB/TrEMBL
  ENSSSCT00030035480 UniProtKB/TrEMBL
  ENSSSCT00030035512 UniProtKB/TrEMBL
  ENSSSCT00035039932 UniProtKB/TrEMBL
  ENSSSCT00035039936 UniProtKB/TrEMBL
  ENSSSCT00035039939 UniProtKB/TrEMBL
  ENSSSCT00035039950 UniProtKB/TrEMBL
  ENSSSCT00035039956 UniProtKB/TrEMBL
  ENSSSCT00035039959 UniProtKB/TrEMBL
  ENSSSCT00035039967 UniProtKB/TrEMBL
  ENSSSCT00040013451 UniProtKB/TrEMBL
  ENSSSCT00040013523 UniProtKB/TrEMBL
  ENSSSCT00040013682 UniProtKB/TrEMBL
  ENSSSCT00040013780 UniProtKB/TrEMBL
  ENSSSCT00045046333 UniProtKB/TrEMBL
  ENSSSCT00045046591 UniProtKB/TrEMBL
  ENSSSCT00045046795 UniProtKB/TrEMBL
  ENSSSCT00050009537 UniProtKB/TrEMBL
  ENSSSCT00050009548 UniProtKB/TrEMBL
  ENSSSCT00050009552 UniProtKB/TrEMBL
  ENSSSCT00050009575 UniProtKB/TrEMBL
  ENSSSCT00050009585 UniProtKB/TrEMBL
  ENSSSCT00050009598 UniProtKB/TrEMBL
  ENSSSCT00050009608 UniProtKB/TrEMBL
  ENSSSCT00055014747 UniProtKB/TrEMBL
  ENSSSCT00055014827 UniProtKB/TrEMBL
  ENSSSCT00055014930 UniProtKB/TrEMBL
  ENSSSCT00055015070 UniProtKB/TrEMBL
  ENSSSCT00055015185 UniProtKB/TrEMBL
  ENSSSCT00060086942 UniProtKB/TrEMBL
  ENSSSCT00060086972 UniProtKB/TrEMBL
  ENSSSCT00060087104 UniProtKB/TrEMBL
  ENSSSCT00060087173 UniProtKB/TrEMBL
  ENSSSCT00065050911 UniProtKB/TrEMBL
  ENSSSCT00065050917 UniProtKB/TrEMBL
  ENSSSCT00065050973 UniProtKB/TrEMBL
  ENSSSCT00070014433 UniProtKB/TrEMBL
  ENSSSCT00070014452 UniProtKB/TrEMBL
  ENSSSCT00070014479 UniProtKB/TrEMBL
InterPro Ca/CaM-dep_prot_kinase-assoc UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  NTF2-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene CAMK2A ENTREZGENE
Pfam CaMKII_AD UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF54427 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A287BAW1_PIG UniProtKB/TrEMBL
  A0A4X1T7G0_PIG UniProtKB/TrEMBL
  A0A4X1TAV3_PIG UniProtKB/TrEMBL
  A0A4X1TAZ9_PIG UniProtKB/TrEMBL
  A0A8D0W7R9_PIG UniProtKB/TrEMBL
  A0A8D0ZCE7_PIG UniProtKB/TrEMBL
  A0A8D0ZCF8_PIG UniProtKB/TrEMBL
  A0A8D1CS00_PIG UniProtKB/TrEMBL
  A0A8D1IJB6_PIG UniProtKB/TrEMBL
  A0A8D1JQ53_PIG UniProtKB/TrEMBL
  A0A8D1JS18_PIG UniProtKB/TrEMBL
  A0A8D1Q4G3_PIG UniProtKB/TrEMBL
  A0A8D1YIF7_PIG UniProtKB/TrEMBL
  F1RL74 ENTREZGENE, UniProtKB/TrEMBL
  I3LNG5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:86155 ENTREZGENE