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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:dopamine signaling pathway via D1 family of receptors
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Accession:PW:0000851 term browser browse the term
Definition:Dopamine signaling via D1-like receptors engages the Galphas family of G proteins leading to activation of adenylyl cyclases and increase in intracellular cAMP. Dopamine receptors 1 and 5 belong to this family.
Synonyms:related_synonym: SMP:00308


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dopamine signaling pathway via D1 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00308 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236 		JBrowse link
G Adcy5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Arrb1 arrestin, beta 1 ISO RGD PMID:21303898 PMID:21303898 RGD:11041134, RGD:11041134 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Drd1 dopamine receptor D1 ISO SMPDB
RGD		 PMID:21303898 SMP:00308, RGD:11041134 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Gnal G protein subunit alpha L ISO RGD PMID:24144882 RGD:11041135 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599 		JBrowse link
G Gnas GNAS complex locus ISO SMPDB SMP:00308 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00308 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00308 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00308 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs7bp regulator of G-protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chr 2:36,133,944...36,231,505
Ensembl chr 2:36,139,201...36,231,505 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2635
      chemical compound signaling pathway 86
        dopamine signaling pathway 41
          dopamine signaling pathway via D1 family of receptors 20
Path 2
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2635
      signaling pathway pertinent to the brain and nervous system 465
        neuron-to-neuron signaling pathways 282
          neuron-to-neuron signaling pathway via the chemical synapse 280
            dopamine signaling pathway 41
              dopamine signaling pathway via D1 family of receptors 20
paths to the root