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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:chemical compound signaling pathway
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Accession:PW:0001162 term browser browse the term
Definition:The signaling pathway initiated by a chemical entity. It could be an organic or inorganic molecule.


show annotations for term's descendants           Sort by:
acetylcholine signaling pathway via muscarinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase ISO RGD PMID:17786266 RGD:8549506 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Chat choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:19478075 RGD:8549592 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO RGD PMID:22685433 RGD:8549594 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 ISO RGD PMID:22685433 RGD:8549594 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs6 regulator of G-protein signaling 6 ISO RGD PMID:22685433 RGD:8549594 NCBI chr 6:102,264,451...102,796,311
Ensembl chr 6:102,264,447...102,824,753 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chr16:7,713,630...7,716,491 JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258 		JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm2 cholinergic receptor, muscarinic 2 ISO RGD PMID:23841840 RGD:8549585 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 ISO RGD PMID:23841840 RGD:8549585 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Gnai1 G protein subunit alpha i1 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 ISO RGD PMID:23841840 RGD:8549585 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 ISO RGD PMID:23841840 RGD:8549585 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 ISO RGD PMID:23841840 RGD:8549585 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gna14 G protein subunit alpha 14 ISO RGD PMID:23759942 RGD:8549590 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423 		JBrowse link
G Gnaq G protein subunit alpha q ISO RGD PMID:23759942 RGD:8549590 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
acetylcholine signaling pathway via nicotinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase ISO RGD PMID:17786266 RGD:8549506 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Agrn agrin ISO RGD PMID:23032192 RGD:8549508 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003 		JBrowse link
G Chat choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit ISO RGD PMID:23032192 PMID:19126755 RGD:8549508, RGD:8549510 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 1:156,487,279...156,494,277
Ensembl chr 1:156,487,279...156,491,476 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr16:64,697,741...64,704,441
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit ISO RGD PMID:23032192 PMID:19126755 RGD:8549508, RGD:8549510 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit ISO RGD PMID:23032192 PMID:19126755 RGD:8549508, RGD:8549510 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit ISO RGD PMID:23032192 PMID:19126755 RGD:8549508, RGD:8549510 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit ISO RGD PMID:23032192 PMID:19126755 RGD:8549508, RGD:8549510 NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Dok7 docking protein 7 ISO RGD PMID:23032192 RGD:8549508 NCBI chr14:75,665,444...75,699,413
Ensembl chr14:75,666,744...75,699,386 		JBrowse link
G Lrp4 LDL receptor related protein 4 ISO RGD PMID:23032192 RGD:8549508 NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593 		JBrowse link
G Musk muscle associated receptor tyrosine kinase ISO RGD PMID:23032192 RGD:8549508 NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932 		JBrowse link
G Rapsn receptor-associated protein of the synapse ISO RGD PMID:23032192 RGD:8549508 NCBI chr 3:77,015,073...77,024,378
Ensembl chr 3:76,983,471...77,024,373 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chr16:7,713,630...7,716,491 JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258 		JBrowse link
dopamine signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5 cyclin-dependent kinase 5 ISO RGD PMID:21927600 RGD:11041163 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 ISO RGD PMID:21927600 RGD:11041163 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Drd1 dopamine receptor D1 IDA
ISO		 heterodimer coupled to Galphaq RGD PMID:17314300 PMID:25671228 RGD:1625010, RGD:11041142 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 IDA
ISO
IMP		 heterodimer coupled to Galphaq RGD PMID:12121979 PMID:25671228 PMID:16490190 PMID:17314300 RGD:1581445, RGD:11041142, RGD:1625068, RGD:1625010 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 IMP RGD PMID:16490190 RGD:1625068 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 IDA RGD PMID:17314300 RGD:1625010 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:25671228 RGD:11041142 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B ISO RGD PMID:21927600 PMID:21303898 RGD:11041163, RGD:11041134 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576 		JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr 8:101,703,512...101,841,530
Ensembl chr 8:101,704,778...101,841,502 		JBrowse link
G Ppp2r5d protein phosphatase 2, regulatory subunit B', delta ISO RGD PMID:21927600 RGD:11041163 NCBI chr 9:14,270,364...14,300,396
Ensembl chr 9:14,268,745...14,300,400 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IDA RGD PMID:16529858 RGD:1581410 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
dopamine signaling pathway via D1 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00308 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236 		JBrowse link
G Adcy5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Arrb1 arrestin, beta 1 ISO RGD PMID:21303898 PMID:21303898 RGD:11041134, RGD:11041134 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Drd1 dopamine receptor D1 ISO SMPDB
RGD		 PMID:21303898 SMP:00308, RGD:11041134 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Gnal G protein subunit alpha L ISO RGD PMID:24144882 RGD:11041135 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599 		JBrowse link
G Gnas GNAS complex locus ISO SMPDB SMP:00308 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00308 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00308 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00308 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs7bp regulator of G-protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chr 2:36,133,944...36,231,505
Ensembl chr 2:36,139,201...36,231,505 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
dopamine signaling pathway via D2 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Arrb1 arrestin, beta 1 ISO RGD PMID:21303898 PMID:21303898 RGD:11041134, RGD:11041134 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:24831693 RGD:11041136 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnao1 G protein subunit alpha o1 ISO RGD PMID:24831693 RGD:11041136 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO
IEP		 RGD PMID:21303898 PMID:23940634 RGD:11041134, RGD:13792715 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs7bp regulator of G-protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chr 2:36,133,944...36,231,505
Ensembl chr 2:36,139,201...36,231,505 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
epinephrine signaling pathway via adrenergic receptor beta term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:19110970 RGD:4140391 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:19110970 RGD:4140391 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Arrb1 arrestin, beta 1 ISO RGD PMID:19229505 PMID:18268361 RGD:5135529, RGD:4140419 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 ISO RGD PMID:19229505 PMID:18268361 RGD:5135529, RGD:4140419 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Gnas GNAS complex locus ISO RGD PMID:19110970 RGD:4140391 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:19110970 PMID:19229505 RGD:4140391, RGD:5135529 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:19110970 PMID:19229505 RGD:4140391, RGD:5135529 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Snx13 sorting nexin 13 ISO RGD PMID:17173929 RGD:4140388 NCBI chr 6:51,758,258...51,862,260
Ensembl chr 6:51,753,036...51,860,224 		JBrowse link
histamine signaling pathway, immunological term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00335 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00335 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Esr1 estrogen receptor 1 ISO SMPDB SMP:00335 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gnas GNAS complex locus ISO SMPDB SMP:00335 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00335 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00335 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712 		JBrowse link
G Hrh2 histamine receptor H 2 ISO SMPDB SMP:00335 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00335 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00335 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
serotonin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:19095043 RGD:39939084 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
serotonin signaling pathway via receptors engaging G alphas protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Esr1 estrogen receptor 1 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gnas GNAS complex locus ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 ISO SMPDB SMP:00309 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO SMPDB SMP:00312 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO SMPDB SMP:00311 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2635
      chemical compound signaling pathway 86
        acetylcholine signaling pathway + 40
        cannabinoid signaling pathway + 0
        dopamine signaling pathway + 41
        epinephrine signaling pathway + 8
        gasotransmitter mediated signaling pathway + 0
        histamine signaling pathway + 9
        melatonin signaling pathway 0
        norepinephrine signaling pathway + 0
        radical mediated signaling pathway + 0
        serotonin signaling pathway + 12
paths to the root