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ONTOLOGY REPORT - ANNOTATIONS

Term:antigen processing and presentation of exogenous peptide antigen via MHC class II
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Accession:GO:0019886 term browser browse the term
Definition:The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
Synonyms:exact_synonym: exogenous peptide antigen processing and presentation via MHC class II
 broad_synonym: antigen presentation, exogenous antigen via MHC class II;   antigen presentation, exogenous peptide antigen;   antigen processing, exogenous antigen via major histocompatibility complex class II
 alt_id: GO:0042591;   GO:0048005


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antigen processing and presentation of exogenous peptide antigen via MHC class II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851 		JBrowse link
G CD74 CD74 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7679955), (PMID:8598040) Ensembl
MGI		 PMID:7679955 PMID:8598040 GO_REF:0000107 NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969 		JBrowse link
G CTSD cathepsin D involved_in TAS Reactome Reactome:R-HSA-2132295 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CTSE cathepsin E involved_in IDA
IEA
IBA		 (PMID:8765029) UniProt
TreeGrafter
GO_Central
Ensembl		 PMID:8765029 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:206,009,264...206,023,895
Ensembl chr 1:206,008,535...206,023,909 		JBrowse link
G CTSF cathepsin F involved_in TAS Reactome Reactome:R-HSA-2132295 NCBI chr11:66,563,464...66,568,606
Ensembl chr11:66,563,464...66,568,879 		JBrowse link
G CTSL cathepsin L involved_in TAS Reactome Reactome:R-HSA-2132295 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CTSS cathepsin S involved_in IDA
TAS		 (PMID:30612035) UniProt
Reactome		 PMID:30612035 Reactome:R-HSA-2132295 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957 		JBrowse link
G CTSV cathepsin V involved_in TAS Reactome Reactome:R-HSA-2132295 NCBI chr 9:97,029,677...97,039,643
Ensembl chr 9:97,029,677...97,156,556 		JBrowse link
G DNM2 dynamin 2 involved_in TAS Reactome Reactome:R-HSA-2132295 NCBI chr19:10,718,079...10,831,903
Ensembl chr19:10,718,055...10,833,488 		JBrowse link
G FCER1G Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:14643301) GO_Central
MGI		 PMID:14643301 GO_REF:0000033 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G FCGR2B Fc gamma receptor IIb involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:26683154)
(PMID:14643301)		 ARUK-UCL
MGI		 PMID:14643301 PMID:26683154 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G HLA-DMA major histocompatibility complex, class II, DM alpha involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:11714799)
(PMID:8598040)
(PMID:11027433)
(PMID:8598041)		 GO_Central
MGI		 PMID:8598040 PMID:8598041 PMID:11027433 PMID:11714799 GO_REF:0000033 NCBI chr 6:32,948,618...32,953,097
Ensembl chr 6:32,948,613...32,969,094 		JBrowse link
G HLA-DMB major histocompatibility complex, class II, DM beta involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA		 (PMID:8139689)
(PMID:11027433)		 UniProt
MGI
GO_Central		 PMID:8139689 PMID:11027433 GO_REF:0000033 NCBI chr 6:32,934,636...32,941,028
Ensembl chr 6:32,934,629...32,941,028 		JBrowse link
G HLA-DOA major histocompatibility complex, class II, DO alpha involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:9492004) Ensembl
MGI
GO_Central		 PMID:9492004 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:33,004,182...33,009,591
Ensembl chr 6:33,004,182...33,009,591 		JBrowse link
G HLA-DOB major histocompatibility complex, class II, DO beta involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:32,812,763...32,817,002
Ensembl chr 6:32,812,763...32,820,466 		JBrowse link
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 involved_in IMP
IBA		 (PMID:20356827) UniProt
GO_Central		 PMID:20356827 GO_REF:0000033 NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775 		JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 involved_in IDA
IBA
IMP		 (PMID:32341563)
(PMID:20356827)		 UniProt
GO_Central		 PMID:20356827 PMID:32341563 GO_REF:0000033 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:11027433), (PMID:11069069), (PMID:11714799), (PMID:7679955), (PMID:8598040), (PMID:8598041), (PMID:9432982), (PMID:9492004) GO_Central
MGI		 PMID:7679955 PMID:8598040 PMID:8598041 PMID:9432982 PMID:9492004 More... GO_REF:0000033 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:32,741,391...32,747,198
Ensembl chr 6:32,741,391...32,747,198 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA		 (PMID:32341563)
(PMID:11027433), (PMID:11069069), (PMID:11714799), (PMID:7679955), (PMID:8598040), (PMID:8598041), (PMID:9432982), (PMID:9492004)		 UniProt
MGI
GO_Central		 PMID:7679955 PMID:8598040 PMID:8598041 PMID:9432982 PMID:9492004 More... GO_REF:0000033 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:32,756,098...32,763,532
Ensembl chr 6:32,756,098...32,763,532 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA		 (PMID:15265931)
(PMID:11027433), (PMID:11714799)		 UniProt
MGI
GO_Central		 PMID:11027433 PMID:11714799 PMID:15265931 GO_REF:0000033 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA		 (PMID:15265931), (PMID:32341563)
(PMID:11027433), (PMID:11714799)		 UniProt
MGI
GO_Central		 PMID:11027433 PMID:11714799 PMID:15265931 PMID:32341563 GO_REF:0000033 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 involved_in IDA
IBA		 (PMID:19531622), (PMID:32341563) UniProt
GO_Central		 PMID:19531622 PMID:32341563 GO_REF:0000033
G HLA-DRB4 major histocompatibility complex, class II, DR beta 4 involved_in IBA GO_Central GO_REF:0000033
G HLA-DRB5 major histocompatibility complex, class II, DR beta 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:32,517,353...32,530,287
Ensembl chr 6:32,517,353...32,530,287 		JBrowse link
G IFI30 IFI30 lysosomal thiol reductase involved_in
acts_upstream_of_or_within		 IEA
ISO
TAS		 (PMID:11701933) Ensembl
MGI
Reactome		 PMID:11701933 GO_REF:0000107 Reactome:R-HSA-2132295 NCBI chr19:18,173,813...18,178,117
Ensembl chr19:18,173,162...18,178,117 		JBrowse link
G LGMN legumain involved_in TAS
IDA		 (PMID:9872320) Reactome
UniProt		 PMID:9872320 Reactome:R-HSA-2132295 NCBI chr14:92,703,809...92,748,627
Ensembl chr14:92,703,807...92,748,679 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IDA (PMID:30612035) UniProt PMID:30612035 NCBI chr 2:208,266,056...208,358,746
Ensembl chr 2:208,266,255...208,358,746 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14499111) Ensembl
MGI		 PMID:14499111 GO_REF:0000107 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16415873) Ensembl
MGI		 PMID:16415873 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
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Term Annotations click to browse term
  biological_process 19669
    immune system process 3226
      antigen processing and presentation 137
        antigen processing and presentation of exogenous antigen 53
          antigen processing and presentation of exogenous peptide antigen 43
            antigen processing and presentation of exogenous peptide antigen via MHC class II 31
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