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Gene: HLA-DMA (major histocompatibility complex, class II, DM alpha) Homo sapiens
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Symbol: HLA-DMA
Name: major histocompatibility complex, class II, DM alpha
Description: Exhibits MHC class II protein complex binding activity. Involved in peptide antigen assembly with MHC class II protein complex. Localizes to the MHC class II protein complex; cell surface; and intracellular membrane-bounded organelle.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: class II histocompatibility antigen, M alpha chain; D6S222E; DMA; HLA class II histocompatibility antigen, DM alpha chain; HLADM; MHC class II antigen DMA; really interesting new gene 6 protein; RING6
Orthologs:
Mus musculus (house mouse) : H2-DMa (histocompatibility 2, class II, locus DMa)  MGI  Alliance
Rattus norvegicus (Norway rat) : RT1-DMa (RT1 class II, locus DMa)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102023843 (HLA class II histocompatibility antigen, DM alpha chain)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100968989 (HLA class II histocompatibility antigen, DM alpha chain)
Canis lupus familiaris (dog) : DLA-DMA (major histocompatibility complex, class II, DM alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101963772 (HLA class II histocompatibility antigen, DM alpha chain)
Sus scrofa (pig) : SLA-DMA (SLA-DM alpha chain)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl632,948,613 - 32,969,094 (-)Ensembl
GRCh38632,948,618 - 32,953,097 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37632,916,391 - 32,920,900 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,024,373 - 33,028,831 (-)NCBINCBI36hg18NCBI36
Build 34633,024,373 - 33,028,831NCBI
Celera634,465,294 - 34,469,805 (-)NCBI
Cytogenetic Map6p21.32NCBI
HuRef632,658,920 - 32,663,431 (-)NCBIHuRef
CHM1_1632,917,186 - 32,921,697 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on HLA-DMA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346716
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.