DLA-DMA (major histocompatibility complex, class II, DM alpha) - Rat Genome Database

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Gene: DLA-DMA (major histocompatibility complex, class II, DM alpha) Canis lupus familiaris
Analyze
No known orthologs.
Symbol: DLA-DMA
Name: major histocompatibility complex, class II, DM alpha
RGD ID: 12144368
Description: ENCODES a protein that exhibits MHC class II protein complex binding (inferred); INVOLVED IN antigen processing and presentation (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); chaperone cofactor-dependent protein refolding (ortholog); FOUND IN endosome membrane (ortholog); late endosome (ortholog); lysosome (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,516,974 - 2,534,085 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,503,325 - 2,533,990 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,598,545 - 2,602,105 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0122,847,916 - 2,865,029 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl122,845,535 - 2,851,482 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,516,014 - 2,519,572 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,597,566 - 2,601,126 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,672,100 - 2,675,661 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Variants

.
Variants in DLA-DMA
177 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCAFT00000001328   ⟹   ENSCAFP00000001218
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl122,516,976 - 2,520,579 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000036735   ⟹   ENSCAFP00000032144
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl122,516,976 - 2,520,536 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000043628   ⟹   ENSCAFP00000042961
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl122,503,325 - 2,508,380 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000061162   ⟹   ENSCAFP00000061800
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl122,503,325 - 2,533,990 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000074446   ⟹   ENSCAFP00000055789
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl122,516,976 - 2,533,990 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845032917   ⟹   ENSCAFP00845025756
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl122,845,535 - 2,851,482 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845032952   ⟹   ENSCAFP00845025785
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl122,847,918 - 2,851,478 (-)Ensembl
RefSeq Acc Id: NM_001048099   ⟹   NP_001041564
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1122,516,976 - 2,520,536 (-)NCBI
Dog10K_Boxer_Tasha122,598,545 - 2,602,105 (-)NCBI
ROS_Cfam_1.0122,847,918 - 2,851,478 (-)NCBI
UMICH_Zoey_3.1122,516,014 - 2,519,572 (-)NCBI
UNSW_CanFamBas_1.0122,597,566 - 2,601,126 (-)NCBI
UU_Cfam_GSD_1.0122,672,100 - 2,675,661 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038682743   ⟹   XP_038538671
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0122,847,916 - 2,851,913 (-)NCBI
RefSeq Acc Id: XM_038682744   ⟹   XP_038538672
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0122,847,916 - 2,865,029 (-)NCBI
RefSeq Acc Id: XM_038682745   ⟹   XP_038538673
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0122,847,916 - 2,851,506 (-)NCBI
RefSeq Acc Id: NP_001041564   ⟸   NM_001048099
- Peptide Label: precursor
- UniProtKB: Q5TJG9 (UniProtKB/TrEMBL),   A0A8C0NF42 (UniProtKB/TrEMBL),   A0A8I3P774 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000055789   ⟸   ENSCAFT00000074446
Ensembl Acc Id: ENSCAFP00000001218   ⟸   ENSCAFT00000001328
Ensembl Acc Id: ENSCAFP00000042961   ⟸   ENSCAFT00000043628
Ensembl Acc Id: ENSCAFP00000061800   ⟸   ENSCAFT00000061162
Ensembl Acc Id: ENSCAFP00000032144   ⟸   ENSCAFT00000036735
RefSeq Acc Id: XP_038538672   ⟸   XM_038682744
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038538671   ⟸   XM_038682743
- Peptide Label: isoform X1
- UniProtKB: A0A8I3PC10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038538673   ⟸   XM_038682745
- Peptide Label: isoform X3
Ensembl Acc Id: ENSCAFP00845025756   ⟸   ENSCAFT00845032917
Ensembl Acc Id: ENSCAFP00845025785   ⟸   ENSCAFT00845032952
Protein Domains
Ig-like   MHC class II alpha chain N-terminal

Promoters
RGD ID:13685373
Promoter ID:EPDNEW_C3438
Type:single initiation site
Name:DLA-DMA_1
Description:major histocompatibility complex, class II, DM alpha precursor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1122,520,540 - 2,520,600EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000848 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030014608 UniProtKB/TrEMBL
  ENSCAFG00040020086 UniProtKB/TrEMBL
  ENSCAFG00845018613 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000001328.5 UniProtKB/TrEMBL
  ENSCAFT00000036735.4 UniProtKB/TrEMBL
  ENSCAFT00030026980.1 UniProtKB/TrEMBL
  ENSCAFT00030027039.1 UniProtKB/TrEMBL
  ENSCAFT00040037152.1 UniProtKB/TrEMBL
  ENSCAFT00040037206.1 UniProtKB/TrEMBL
  ENSCAFT00845032917 ENTREZGENE
  ENSCAFT00845032917.1 UniProtKB/TrEMBL
  ENSCAFT00845032952 ENTREZGENE
  ENSCAFT00845032952.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC/Immunoglobulin UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_II_a/b_N UniProtKB/TrEMBL
  MHC_II_a_N UniProtKB/TrEMBL
KEGG Report cfa:481732 UniProtKB/TrEMBL
NCBI Gene DLA-DMA ENTREZGENE
PANTHER HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM ALPHA CHAIN UniProtKB/TrEMBL
  MHC CLASS II-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_II_alpha UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
  MHC_II_alpha UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF54452 UniProtKB/TrEMBL
UniProt A0A8C0NF42 ENTREZGENE
  A0A8I3P774 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PC10 ENTREZGENE, UniProtKB/TrEMBL
  Q5TJG7_CANLF UniProtKB/TrEMBL
  Q5TJG8_CANLF UniProtKB/TrEMBL
  Q5TJG9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8C0NF42 UniProtKB/TrEMBL
  A0A8C0Z2T0 UniProtKB/TrEMBL
  E2QT44 UniProtKB/TrEMBL