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Gene: DNM2 (dynamin 2) Homo sapiens
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Symbol: DNM2
Name: dynamin 2
RGD ID: 730970
Description: Exhibits SH3 domain binding activity. Involved in negative regulation of membrane tubulation; receptor internalization; and transferrin transport. Localizes to several cellular components, including Golgi apparatus; microtubule; and postsynaptic membrane. Predicted to colocalize with growth cone. Implicated in Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and lethal congenital contracture syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; dynamin II; dynamin-2; DYNII; LCCS5
Orthologs:
Mus musculus (house mouse) : Dnm2 (dynamin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dnm2 (dynamin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnm2 (dynamin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DNM2 (dynamin 2)
Canis lupus familiaris (dog) : DNM2 (dynamin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnm2 (dynamin 2)
Sus scrofa (pig) : DNM2 (dynamin 2)
Chlorocebus sabaeus (African green monkey) : DNM2 (dynamin 2)
Heterocephalus glaber (naked mole-rat) : Dnm2 (dynamin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1910,718,079 - 10,833,488 (+)EnsemblGRCh38hg38GRCh38
GRCh381910,718,079 - 10,831,903 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,828,729 - 10,944,169 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,689,755 - 10,803,579 (+)NCBINCBI36hg18NCBI36
Build 341910,689,754 - 10,803,579NCBI
Celera1910,723,575 - 10,837,431 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,405,937 - 10,520,718 (+)NCBIHuRef
CHM1_11910,829,940 - 10,943,823 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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