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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of epidermal growth factor receptor signaling pathway
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Accession:GO:0045742 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
Synonyms:exact_synonym: positive regulation of EGF receptor signaling pathway;   positive regulation of EGF receptor signalling pathway;   positive regulation of EGFR signaling pathway;   up regulation of epidermal growth factor receptor signaling pathway;   upregulation of epidermal growth factor receptor signaling pathway
 narrow_synonym: activation of epidermal growth factor receptor signaling pathway;   stimulation of epidermal growth factor receptor signaling pathway


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positive regulation of epidermal growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in
acts_upstream_of		 IMP
ISS		 (PMID:17655843)
(PMID:10433800)		 BHF-UCL PMID:10433800 PMID:17655843 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in IDA (PMID:17655843) BHF-UCL PMID:17655843 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907 		JBrowse link
G AFAP1L2 actin filament associated protein 1 like 2 involved_in IDA
IBA		 (PMID:17412687) HGNC-UCL
GO_Central		 PMID:17412687 GO_REF:0000033 NCBI chr10:114,280,725...114,405,175
Ensembl chr10:114,294,824...114,404,756 		JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IMP (PMID:25666625) UniProt PMID:25666625 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
G AGT angiotensinogen involved_in IDA (PMID:15652490) BHF-UCL PMID:15652490 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070 		JBrowse link
G CBL Cbl proto-oncogene involved_in TAS Reactome Reactome:R-HSA-8849469 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926 		JBrowse link
G CCDC88A coiled-coil domain containing 88A involved_in IDA (PMID:20462955) UniProt PMID:20462955 NCBI chr 2:55,287,842...55,419,856
Ensembl chr 2:55,287,842...55,419,895 		JBrowse link
G CNOT9 CCR4-NOT transcription complex subunit 9 involved_in IMP (PMID:20878056) UniProt PMID:20878056 NCBI chr 2:218,568,839...218,597,080
Ensembl chr 2:218,568,580...218,597,080 		JBrowse link
G DGKD diacylglycerol kinase delta involved_in IEA
TAS
ISS		 (PMID:20064931) Ensembl
UniProt		 PMID:20064931 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:233,354,494...233,472,098
Ensembl chr 2:233,354,494...233,472,104 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:17928626 RGD:5128669 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:17928626 RGD:5128669 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAM83B family with sequence similarity 83 member B involved_in IMP
IDA		 (PMID:22886302), (PMID:23912460)
(PMID:23676467)		 UniProt PMID:22886302 PMID:23676467 PMID:23912460 NCBI chr 6:54,846,203...54,945,099
Ensembl chr 6:54,846,771...54,945,099 		JBrowse link
G FASLG Fas ligand involved_in ISO
IEA		 RGD
Ensembl		 PMID:18471522 GO_REF:0000107 RGD:2315731 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA
IDA		 (PMID:15705806) RGD
Ensembl
UniProt		 PMID:15705806 PMID:20445128 GO_REF:0000107 RGD:4892084 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815 		JBrowse link
G HAP1 huntingtin associated protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:41,717,739...41,734,646
Ensembl chr17:41,717,742...41,734,644 		JBrowse link
G HIP1 huntingtin interacting protein 1 involved_in IMP (PMID:14732715) ParkinsonsUK-UCL PMID:14732715 NCBI chr 7:75,533,298...75,738,941
Ensembl chr 7:75,533,298...75,738,962 		JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in IMP (PMID:14732715) ParkinsonsUK-UCL PMID:14732715 NCBI chr12:122,834,748...122,862,961
Ensembl chr12:122,834,453...122,862,961 		JBrowse link
G MIR29A microRNA 29a involved_in IMP (PMID:25058496) FlyBase PMID:25058496 NCBI chr 7:130,876,747...130,876,810
Ensembl chr 7:130,876,747...130,876,810 		JBrowse link
G MMP9 matrix metallopeptidase 9 involved_in IMP (PMID:22984561) CACAO PMID:22984561 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NEU3 neuraminidase 3 involved_in IMP (PMID:17334392) UniProt PMID:17334392 NCBI chr11:74,980,515...75,020,676
Ensembl chr11:74,988,279...75,018,893 		JBrowse link
G NUP62 nucleoporin 62 involved_in NAS (PMID:11244088) UniProt PMID:11244088 NCBI chr19:49,906,825...49,929,504
Ensembl chr19:49,906,825...49,929,764 		JBrowse link
G PDE6G phosphodiesterase 6G involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:11502744) Ensembl
MGI
GO_Central		 PMID:11502744 GO_REF:0000033 GO_REF:0000107 NCBI chr17:81,650,459...81,663,127
Ensembl chr17:81,650,459...81,663,112 		JBrowse link
G PDE6H phosphodiesterase 6H involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:11502744) Ensembl
MGI
GO_Central		 PMID:11502744 GO_REF:0000033 GO_REF:0000107 NCBI chr12:14,973,042...14,981,865
Ensembl chr12:14,973,042...14,981,865 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor involved_in IMP (PMID:22984561) CACAO PMID:22984561 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PTK6 protein tyrosine kinase 6 involved_in TAS Reactome Reactome:R-HSA-8849469 NCBI chr20:63,528,001...63,537,376
Ensembl chr20:63,528,001...63,537,376 		JBrowse link
G RALA RAS like proto-oncogene A involved_in IGI (PMID:34096503) FlyBase PMID:34096503 NCBI chr 7:39,623,572...39,708,120
Ensembl chr 7:39,623,565...39,708,120 		JBrowse link
G RALB RAS like proto-oncogene B involved_in IGI (PMID:34096503) FlyBase PMID:34096503 NCBI chr 2:120,240,070...120,294,710
Ensembl chr 2:120,240,064...120,294,710 		JBrowse link
G SHKBP1 SH3KBP1 binding protein 1 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:40,576,873...40,591,397
Ensembl chr19:40,576,853...40,591,399 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:8577724 GO_REF:0000107 RGD:1581110 NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:80,335,976...80,341,126
Ensembl chr13:80,335,976...80,341,126 		JBrowse link
G TGFB1 transforming growth factor beta 1 acts_upstream_of IDA (PMID:18625725) BHF-UCL PMID:18625725 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19715
    cellular process 18967
      signal transduction 6636
        positive regulation of signal transduction 1822
          positive regulation of ERBB signaling pathway 34
            positive regulation of epidermal growth factor receptor signaling pathway 32
              positive regulation of epidermal growth factor receptor signaling pathway involved in heart process 0
Path 2
Term Annotations click to browse term
  biological_process 19715
    biological regulation 13546
      regulation of biological process 13144
        regulation of cellular process 12755
          signal transduction 6636
            cell surface receptor signaling pathway 3204
              enzyme-linked receptor protein signaling pathway 1172
                cell surface receptor protein tyrosine kinase signaling pathway 728
                  ERBB signaling pathway 192
                    regulation of ERBB signaling pathway 82
                      positive regulation of ERBB signaling pathway 34
                        positive regulation of epidermal growth factor receptor signaling pathway 32
                          positive regulation of epidermal growth factor receptor signaling pathway involved in heart process 0
paths to the root