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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of ERBB signaling pathway
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Accession:GO:1901186 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway.
Synonyms:exact_synonym: activation of EGF receptor family signaling pathway;   activation of ERBB signalling pathway;   activation of ErbB signaling;   positive regulation of EGF receptor family signaling pathway;   positive regulation of ERBB signalling pathway;   positive regulation of ErbB signaling;   up regulation of EGF receptor family signaling pathway;   up regulation of ERBB signaling pathway;   up regulation of ERBB signalling pathway;   up regulation of ErbB signaling;   upregulation of EGF receptor family signaling pathway;   upregulation of ERBB signaling pathway;   upregulation of ERBB signalling pathway;   upregulation of ErbB signaling
 narrow_synonym: activation of ERBB signaling pathway
 related_synonym: activation of EGFR family signaling pathway;   positive regulation of EGFR family signaling pathway;   up regulation of EGFR family signaling pathway;   upregulation of EGFR family signaling pathway


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positive regulation of ERBB signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:3701380 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
positive regulation of epidermal growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afap1l2 actin filament associated protein 1-like 2 involved_in IBA
ISO
PMID:21873635
(PMID:17412687)
RGD PMID:17412687, PMID:21873635 RGD:13792537 NCBI chr 1:277,730,760...277,827,299
Ensembl chr 1:277,730,760...277,827,269
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:25666625) RGD PMID:25666625 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Agt angiotensinogen involved_in ISO (PMID:15652490) RGD PMID:15652490 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) RGD PMID:23389627 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member involved_in ISO
IEA
(PMID:18722344)
GO_REF:0000107
RGD
Ensembl
PMID:18722344 GO_REF:0000107 NCBI chr 2:226,563,050...226,679,449
Ensembl chr 2:226,563,050...226,679,438
JBrowse link
G Ccdc88a coiled coil domain containing 88A involved_in ISO (PMID:20462955) RGD PMID:20462955 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263
JBrowse link
G Cnot9 CCR4-NOT transcription complex subunit 9 involved_in ISO (PMID:20878056) RGD PMID:20878056 NCBI chr 9:81,783,349...81,808,815
Ensembl chr 9:81,783,349...81,808,805
JBrowse link
G Dgkd diacylglycerol kinase, delta involved_in ISO (MGI:3691361|PMID:17021016) RGD PMID:17021016 MGI:3691361 NCBI chr 9:94,980,328...95,071,531
Ensembl chr 9:94,980,409...95,069,714
JBrowse link
G Esr1 estrogen receptor 1 IMP RGD PMID:17928626 RGD:5128669 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 IMP RGD PMID:17928626 RGD:5128669 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Faslg Fas ligand IMP RGD PMID:18471522 RGD:2315731 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IMP
IEA
ISO
GO_REF:0000107
(MGI:5141337|PMID:21673097)
(PMID:15705806)
Ensembl
RGD
PMID:15705806 PMID:21673097, PMID:20445128 GO_REF:0000107 MGI:5141337, RGD:4892084 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in IMP PMID:12890790 UniProt PMID:12890790 RGD:10047165 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210
JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO (PMID:14732715) RGD PMID:14732715 NCBI chr12:24,180,795...24,315,373
Ensembl chr12:24,180,937...24,315,373
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO (PMID:14732715) RGD PMID:14732715 NCBI chr12:38,024,517...38,053,184
Ensembl chr12:38,024,519...38,053,085
JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in ISO
IEA
(PMID:22984561)
GO_REF:0000107
RGD
Ensembl
PMID:22984561 GO_REF:0000107 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Neu3 neuraminidase 3 involved_in ISO (PMID:17334392) RGD PMID:17334392 NCBI chr 1:164,803,574...164,814,777
Ensembl chr 1:164,803,574...164,814,651
JBrowse link
G Pde6g phosphodiesterase 6G involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2156093|PMID:11502744)
RGD PMID:11502744, PMID:21873635 MGI:2156093, RGD:13792537 NCBI chr10:109,620,499...109,625,214
Ensembl chr10:109,620,980...109,622,745
JBrowse link
G Pde6h phosphodiesterase 6H involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2156093|PMID:11502744)
RGD PMID:11502744, PMID:21873635 MGI:2156093, RGD:13792537 NCBI chr 4:170,947,723...170,963,046
Ensembl chr 4:170,958,196...170,963,046
JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO
IEA
(PMID:22984561)
GO_REF:0000107
RGD
Ensembl
PMID:22984561 GO_REF:0000107 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Shkbp1 Sh3kbp1 binding protein 1 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5700492|PMID:21830225)
GO_REF:0000024
RGD
UniProt
PMID:21830225, PMID:21873635 GO_REF:0000024 MGI:5700492, RGD:13792537 NCBI chr 1:84,154,703...84,168,074
Ensembl chr 1:84,154,703...84,168,074
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IEP RGD PMID:8577724 RGD:1581110 NCBI chr 6:3,105,443...3,182,977
Ensembl chr 6:3,104,861...3,182,996
JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA
(PMID:17655843), (PMID:18483258)
GO_REF:0000107
RGD
Ensembl
PMID:17655843 PMID:18483258 GO_REF:0000107 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19574994 RGD:2317913 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:17655843) RGD PMID:17655843 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Areg amphiregulin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Btc betacellulin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:18,231,854...18,270,621
Ensembl chr14:18,231,860...18,272,484
JBrowse link
G Egf epidermal growth factor involved_in ISO (PMID:15611079), (PMID:20353436), (PMID:22732145) RGD PMID:15611079 PMID:20353436 PMID:22732145 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Epgn epithelial mitogen involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:1934957|PMID:11278323)
PMID:21873635
(PMID:15611079)
HGNC-UCL
RGD
PMID:11278323 PMID:15611079, PMID:21873635 GO_REF:0000024 MGI:1934957, RGD:13792537 NCBI chr14:18,627,103...18,635,135
Ensembl chr14:18,626,644...18,634,309
JBrowse link
G Ereg epiregulin involved_in IBA
IDA
PMID:21873635
PMID:9990076
GO_Central
UniProt
PMID:21873635, PMID:9990076 RGD:13792537, RGD:632743 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:2152037 (MGI:2149168|PMID:11481456) RGD PMID:11481456 MGI:2149168 NCBI chr 1:266,953,006...267,038,879
Ensembl chr 1:266,952,561...267,038,883
JBrowse link
G Tgfa transforming growth factor alpha involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11278323)
HGNC-UCL
RGD
PMID:11278323, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
positive regulation of ERBB3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtn4 reticulon 4 involved_in ISO
IEA
(PMID:27353365)
GO_REF:0000107
RGD
Ensembl
PMID:27353365 GO_REF:0000107 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      signal transduction 6881
        positive regulation of signal transduction 1597
          positive regulation of ERBB signaling pathway 37
            positive regulation of ERBB3 signaling pathway 1
            positive regulation of epidermal growth factor receptor signaling pathway + 35
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          signal transduction 6881
            cell surface receptor signaling pathway 2774
              enzyme linked receptor protein signaling pathway 978
                transmembrane receptor protein tyrosine kinase signaling pathway 613
                  ERBB signaling pathway 115
                    regulation of ERBB signaling pathway 77
                      positive regulation of ERBB signaling pathway 37
                        positive regulation of ERBB3 signaling pathway 1
                        positive regulation of epidermal growth factor receptor signaling pathway + 35
paths to the root