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ONTOLOGY REPORT - ANNOTATIONS

Term:Leydig cell differentiation
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Accession:GO:0033327 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.


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Leydig cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amh anti-Mullerian hormone involved_in ISO
ISS		 (MGI:1195636|PMID:9435237)
GO_REF:0000024		 RGD
UniProt		 PMID:9435237 GO_REF:0000024 MGI:1195636 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Ar androgen receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3717246 (PMID:19574395)		 Ensembl
RGD		 PMID:19574395 GO_REF:0000107 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Ccnd1 cyclin D1 IMP RGD PMID:17303663 RGD:2289137 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Dhh desert hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1095403|MGI:1934259 (PMID:12050120), (PMID:17495005) RGD PMID:12050120 PMID:17495005 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 IEP RGD PMID:12810569 RGD:2302236 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP RGD PMID:18502897 RGD:4781870 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Map7 microtubule-associated protein 7 acts_upstream_of_or_within ISO MGI:2148221 (PMID:10837026) RGD PMID:10837026 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 IEP RGD PMID:15149725 RGD:2302287 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857494 (PMID:12399445)		 Ensembl
RGD		 PMID:12399445 GO_REF:0000107 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1346833|MGI:2159321 (PMID:11564714), (PMID:15829514)		 Ensembl
RGD		 PMID:11564714 PMID:15829514 GO_REF:0000107 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 acts_upstream_of_or_within ISO MGI:1352460 (PMID:15829514) RGD PMID:15829514 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2449440|MGI:3689423 (PMID:19056881)		 Ensembl
RGD		 PMID:19056881 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 acts_upstream_of_or_within ISO MGI:3526857 (PMID:19056881) RGD PMID:19056881 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156 		JBrowse link
G Sf1 splicing factor 1 acts_upstream_of_or_within ISO MGI:94891 (PMID:17495005) RGD PMID:17495005 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3526851 (PMID:19056881)		 Ensembl
RGD		 PMID:19056881 GO_REF:0000107 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084 		JBrowse link
G Tmf1 TATA element modulatory factor 1 acts_upstream_of_or_within ISO MGI:4867392 (PMID:23000399) RGD PMID:23000399 NCBI chr 4:129,759,952...129,785,705
Ensembl chr 4:129,763,114...129,785,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    reproductive process 1836
      developmental process involved in reproduction 1218
        Leydig cell differentiation 20
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            reproductive system development 435
              reproductive structure development 430
                gonad development 338
                  male gonad development 207
                    Leydig cell differentiation 20
paths to the root