Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:T cell differentiation in thymus
go back to main search page
Accession:GO:0033077 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: thymic T cell differentiation;   thymocyte cell differentiation;   thymocyte differentiation
 related_synonym: T cell development in thymus

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of ISO (PMID:11435465)
(PMID:11067867), (PMID:12163459), (PMID:16670300)
(PMID:11067867), (PMID:16670300)		 MGI PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (MGI:3828349|PMID:17371977) BHF-UCL PMID:17371977 MGI:3828349 NCBI chrNW_004955487:5,180,241...5,218,298
Ensembl chrNW_004955487:5,180,252...5,218,216 		JBrowse link
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO (PMID:16025118) MGI PMID:16025118 NCBI chrNW_004955418:2,567,804...2,675,062
Ensembl chrNW_004955418:2,566,975...2,674,832 		JBrowse link
G B2m beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:18776904) MGI PMID:18776904 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Bcl11b BCL11 transcription factor B acts_upstream_of_or_within ISO (PMID:16670294) MGI PMID:16670294 NCBI chrNW_004955438:20,562,345...20,637,662
Ensembl chrNW_004955438:20,564,449...20,637,103 		JBrowse link
G Bcl2 BCL2 apoptosis regulator acts_upstream_of_or_within ISO (PMID:8170972), (PMID:9028316) MGI PMID:8170972 PMID:9028316 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:23334952) MGI PMID:23334952 NCBI chrNW_004955494:2,567,238...2,712,708 JBrowse link
G Cd3e CD3e molecule ISO RGD PMID:11896936 RGD:2313407 NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990 		JBrowse link
G Cdk6 cyclin dependent kinase 6 acts_upstream_of_or_within ISO (PMID:21508411) MGI PMID:21508411 NCBI chrNW_004955432:9,521,794...9,727,772
Ensembl chrNW_004955432:9,521,794...9,726,417 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (PMID:16025118) MGI PMID:16025118 NCBI chrNW_004955420:29,030,716...29,047,447
Ensembl chrNW_004955420:29,030,716...29,047,449 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 acts_upstream_of_or_within ISO (PMID:15879105) MGI PMID:15879105 NCBI chrNW_004955442:12,971,031...13,002,605
Ensembl chrNW_004955442:12,967,438...13,010,943 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO (MGI:5291865|PMID:21876153) UniProt PMID:21876153 MGI:5291865 NCBI chrNW_004955422:16,026,323...16,035,808
Ensembl chrNW_004955422:16,031,280...16,036,281 		JBrowse link
G Fzd5 frizzled class receptor 5 acts_upstream_of_or_within ISO (PMID:11265645) MGI PMID:11265645 NCBI chrNW_004955457:7,282,403...7,288,918
Ensembl chrNW_004955457:7,282,403...7,288,918 		JBrowse link
G Fzd7 frizzled class receptor 7 acts_upstream_of_or_within ISO (PMID:11265645) MGI PMID:11265645 NCBI chrNW_004955457:12,729,277...12,733,057
Ensembl chrNW_004955457:12,731,279...12,732,979 		JBrowse link
G Fzd8 frizzled class receptor 8 acts_upstream_of_or_within ISO (PMID:11265645) MGI PMID:11265645 NCBI chrNW_004955462:5,870,410...5,873,714 JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:8945476)
(PMID:14670303)
(PMID:18776904)
(PMID:19934022)		 MGI PMID:8945476 PMID:14670303 PMID:18776904 PMID:19934022 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:22665763) MGI PMID:22665763 NCBI chrNW_004955545:1,682,097...1,689,373
Ensembl chrNW_004955545:1,682,097...1,689,376 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO (PMID:15855276) MGI PMID:15855276 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of ISO (PMID:9252128)
(PMID:9916699)		 MGI PMID:9252128 PMID:9916699 NCBI chrNW_004955475:10,676,592...10,680,565
Ensembl chrNW_004955475:10,676,870...10,680,517 		JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of ISO (PMID:9215626) MGI PMID:9215626 NCBI chrNW_004955426:20,785,896...20,818,512
Ensembl chrNW_004955426:20,787,471...20,818,577 		JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase acts_upstream_of_or_within ISO (PMID:14715629) MGI PMID:14715629 NCBI chrNW_004955506:5,577,735...5,588,307
Ensembl chrNW_004955506:5,577,437...5,588,372 		JBrowse link
G LOC102013688 major histocompatibility complex class I-related gene protein involved_in ISO (MGI:3664456|PMID:12634786) UniProt PMID:12634786 MGI:3664456 NCBI chrNW_004955406:20,098,544...20,117,065
Ensembl chrNW_004955406:20,098,538...20,125,057 		JBrowse link
G Mafb MAF bZIP transcription factor B acts_upstream_of_or_within ISO (PMID:19164599) MGI PMID:19164599 NCBI chrNW_004955445:16,219,675...16,222,913 JBrowse link
G Mpzl2 myelin protein zero like 2 acts_upstream_of_or_within ISO (PMID:19851463) MGI PMID:19851463 NCBI chrNW_004955412:19,422,532...19,434,596
Ensembl chrNW_004955412:19,422,537...19,434,596 		JBrowse link
G Ncaph2 non-SMC condensin II complex subunit H2 acts_upstream_of_or_within ISO (PMID:17640884) MGI PMID:17640884 NCBI chrNW_004955413:33,492,348...33,503,804 JBrowse link
G Ncor1 nuclear receptor corepressor 1 acts_upstream_of_or_within ISO (PMID:11030619) MGI PMID:11030619 NCBI chrNW_004955467:1,408,292...1,568,539
Ensembl chrNW_004955467:1,409,281...1,546,842 		JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of ISO (PMID:11931770) MGI PMID:11931770 NCBI chrNW_004955468:2,680,934...2,688,797
Ensembl chrNW_004955468:2,680,806...2,689,155 		JBrowse link
G Nkap NFKB activating protein acts_upstream_of_or_within ISO (PMID:20610818) MGI PMID:20610818 NCBI chrNW_004955534:106,122...119,508
Ensembl chrNW_004955534:106,122...119,344 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO (PMID:9768755) MGI PMID:9768755 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
G Prr7 proline rich 7, synaptic involved_in ISO (PMID:27657535) MGI PMID:27657535 NCBI chrNW_004955408:29,685,254...29,695,113
Ensembl chrNW_004955408:29,692,004...29,695,113 		JBrowse link
G Psmb11 proteasome subunit beta 11 acts_upstream_of_or_within ISO (PMID:31915251) MGI PMID:31915251 NCBI chrNW_004955409:37,260,080...37,260,866 JBrowse link
G Rabl3 RAB, member of RAS oncogene family like 3 involved_in ISO (MGI:6405642|PMID:32220963) UniProt PMID:32220963 MGI:6405642 NCBI chrNW_004955427:20,204,901...20,242,242
Ensembl chrNW_004955427:20,204,901...20,242,242 		JBrowse link
G Rag1 recombination activating 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:50458|PMID:1547488)
(PMID:9215624)		 UniProt
MGI		 PMID:1547488 PMID:9215624 MGI:50458 NCBI chrNW_004955422:9,891,878...9,928,569
Ensembl chrNW_004955422:9,891,878...9,919,504 		JBrowse link
G Rag2 recombination activating 2 involved_in ISO (MGI:50458|PMID:1547488) UniProt PMID:1547488 MGI:50458 NCBI chrNW_004955422:9,867,307...9,869,732
Ensembl chrNW_004955422:9,867,307...9,869,732 		JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 involved_in ISO (MGI:5291865|PMID:21876153) UniProt PMID:21876153 MGI:5291865 NCBI chrNW_004955409:35,961,604...35,965,477
Ensembl chrNW_004955409:35,937,880...35,965,712 		JBrowse link
G Rorc RAR related orphan receptor C acts_upstream_of_or_within ISO (PMID:15247480) MGI PMID:15247480 NCBI chrNW_004955589:590,653...616,784
Ensembl chrNW_004955589:590,743...616,694 		JBrowse link
G Rps6 ribosomal protein S6 acts_upstream_of_or_within ISO (PMID:16357222) MGI PMID:16357222 NCBI chrNW_004955434:21,744,045...21,745,646
Ensembl chrNW_004955434:21,744,082...21,746,626 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of		 ISO (MGI:3847177|PMID:19273836)
(PMID:10981962)		 BHF-UCL
MGI		 PMID:10981962 PMID:19273836 MGI:3847177 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:15294943) MGI PMID:15294943 NCBI chrNW_004955451:16,305,363...16,319,219
Ensembl chrNW_004955451:16,305,363...16,318,534 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within ISO (PMID:15294943) MGI PMID:15294943 NCBI chrNW_004955451:16,253,645...16,295,337
Ensembl chrNW_004955451:16,255,398...16,272,214 		JBrowse link
G Tcf3 transcription factor 3 acts_upstream_of_or_within ISO (PMID:18958875) MGI PMID:18958875 NCBI chrNW_004955495:6,337,311...6,365,193
Ensembl chrNW_004955495:6,337,870...6,367,487 		JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (PMID:28598420) MGI PMID:28598420 NCBI chrNW_004955458:2,084,931...2,108,328
Ensembl chrNW_004955458:2,084,868...2,108,335 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (PMID:16357222) MGI PMID:16357222 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (PMID:11265645) MGI PMID:11265645 NCBI chrNW_004955500:7,797,063...7,811,142
Ensembl chrNW_004955500:7,797,060...7,811,167 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO (PMID:11265645) MGI PMID:11265645 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 acts_upstream_of_or_within ISO (PMID:22201126) MGI PMID:22201126 NCBI chrNW_004955466:5,353,355...5,376,240
Ensembl chrNW_004955466:5,355,344...5,376,240 		JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 involved_in ISO (MGI:4818820|PMID:20622884) UniProt
BHF-UCL		 PMID:20622884 MGI:4818820 NCBI chrNW_004955466:1,541,367...1,546,617
Ensembl chrNW_004955466:1,541,323...1,546,617 		JBrowse link
G Zfp36l2 ZFP36 ring finger protein like 2 involved_in ISO (MGI:4818820|PMID:20622884) UniProt
BHF-UCL		 PMID:20622884 MGI:4818820 NCBI chrNW_004955441:10,467,608...10,469,885 JBrowse link
DN2 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in ISO (MGI:5784970|PMID:24638065) UniProt PMID:24638065 MGI:5784970 NCBI chrNW_004955439:14,921,524...14,949,493
Ensembl chrNW_004955439:14,920,601...14,924,191 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (PMID:10911993), (PMID:9823897) MGI PMID:9823897 PMID:10911993 NCBI chrNW_004955404:3,606,077...3,615,193
Ensembl chrNW_004955404:3,606,077...3,615,193 		JBrowse link
G Rag2 recombination activating 2 acts_upstream_of_or_within ISO (PMID:9875844) MGI PMID:9875844 NCBI chrNW_004955422:9,867,307...9,869,732
Ensembl chrNW_004955422:9,867,307...9,869,732 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:9875844) MGI PMID:9875844 NCBI chrNW_004955418:27,174,510...27,426,245
Ensembl chrNW_004955418:27,173,659...27,426,264 		JBrowse link
DN3 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in ISO (MGI:5784970|PMID:24638065) UniProt PMID:24638065 MGI:5784970 NCBI chrNW_004955439:14,921,524...14,949,493
Ensembl chrNW_004955439:14,920,601...14,924,191 		JBrowse link
DN4 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18025176) MGI PMID:18025176 NCBI chrNW_004955513:652,048...799,182
Ensembl chrNW_004955513:653,252...799,239 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18025176) MGI PMID:18025176 NCBI chrNW_004955406:18,435,984...18,527,967
Ensembl chrNW_004955406:18,437,672...18,527,698 		JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:17210642) MGI PMID:17210642 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687 		JBrowse link
G Nfatc3 nuclear factor of activated T cells 3 involved_in ISO (MGI:3820023|PMID:17579027) UniProt PMID:17579027 MGI:3820023 NCBI chrNW_004955484:8,433,765...8,558,005
Ensembl chrNW_004955484:8,436,330...8,526,680 		JBrowse link
immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of ISO (PMID:17210642) MGI PMID:17210642 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687 		JBrowse link
G Clec4g C-type lectin domain family 4 member G acts_upstream_of ISO (PMID:23487419) MGI PMID:23487419 NCBI chrNW_004955563:1,571,374...1,574,901
Ensembl chrNW_004955563:1,571,288...1,575,979 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 acts_upstream_of ISO (PMID:16230479) MGI PMID:16230479 NCBI chrNW_004955451:14,442,816...14,456,009
Ensembl chrNW_004955451:14,442,816...14,459,379 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of ISO (PMID:16230479) MGI PMID:16230479 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 acts_upstream_of_or_within ISO (PMID:11154225) MGI PMID:11154225 NCBI chrNW_004955407:32,601,862...32,637,852
Ensembl chrNW_004955407:32,601,826...32,638,564 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of ISO (PMID:11894098) MGI PMID:11894098 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO (PMID:18617424) MGI PMID:18617424 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:12421925) BHF-UCL PMID:12421925 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303 		JBrowse link
G Clec4g C-type lectin domain family 4 member G acts_upstream_of_or_within ISO (PMID:23487419) MGI PMID:23487419 NCBI chrNW_004955563:1,571,374...1,574,901
Ensembl chrNW_004955563:1,571,288...1,575,979 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 acts_upstream_of_or_within ISO (PMID:16230479) MGI PMID:16230479 NCBI chrNW_004955451:14,442,816...14,456,009
Ensembl chrNW_004955451:14,442,816...14,459,379 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) BHF-UCL PMID:19109233 MGI:3836494 NCBI chrNW_004955453:14,376,665...14,382,536
Ensembl chrNW_004955453:14,376,718...14,381,747 		JBrowse link
G Tmem131l transmembrane 131 like involved_in ISO (PMID:23690469) UniProt PMID:23690469 NCBI chrNW_004955471:7,797,687...7,952,265
Ensembl chrNW_004955471:7,797,780...7,952,131 		JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:5320871|PMID:22080863) UniProt PMID:22080863 MGI:5320871 NCBI chrNW_004955402:771,410...846,671 JBrowse link
negative regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:12421925) BHF-UCL PMID:12421925 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303 		JBrowse link
G Foxj1 forkhead box J1 involved_in ISO (MGI:3713603|PMID:16339515) BHF-UCL PMID:16339515 MGI:3713603 NCBI chrNW_004955506:6,127,551...6,132,302
Ensembl chrNW_004955506:6,127,551...6,132,302 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) BHF-UCL PMID:19109233 MGI:3836494 NCBI chrNW_004955453:14,376,665...14,382,536
Ensembl chrNW_004955453:14,376,718...14,381,747 		JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of_or_within ISO (PMID:11931770) MGI PMID:11931770 NCBI chrNW_004955468:2,680,934...2,688,797
Ensembl chrNW_004955468:2,680,806...2,689,155 		JBrowse link
G Rag2 recombination activating 2 ISO RGD PMID:30206106 RGD:38508903 NCBI chrNW_004955422:9,867,307...9,869,732
Ensembl chrNW_004955422:9,867,307...9,869,732 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO (PMID:10981962) MGI PMID:10981962 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Zc3h8 zinc finger CCCH-type containing 8 involved_in ISO (PMID:12153508) UniProt PMID:12153508 NCBI chrNW_004955470:1,888,903...1,913,077
Ensembl chrNW_004955470:1,888,871...1,916,581 		JBrowse link
negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator acts_upstream_of_or_within ISO (PMID:23382543) MGI PMID:23382543 NCBI chrNW_004955407:41,157,503...41,165,032
Ensembl chrNW_004955407:41,157,484...41,165,014 		JBrowse link
G Atg5 autophagy related 5 acts_upstream_of_or_within ISO (PMID:23382543) MGI PMID:23382543 NCBI chrNW_004955411:31,501,191...31,646,407
Ensembl chrNW_004955411:31,522,420...31,646,827 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3847607|PMID:17785582) BHF-UCL PMID:17785582 MGI:3847607 NCBI chrNW_004955451:15,086,119...15,101,862
Ensembl chrNW_004955451:15,086,119...15,095,561 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (PMID:7630421) MGI PMID:7630421 NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990 		JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO (PMID:7679955) MGI PMID:7679955 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826 		JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO (PMID:12871644) MGI PMID:12871644 NCBI chrNW_004955408:22,630,375...23,059,832
Ensembl chrNW_004955408:22,630,364...23,059,899 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (MGI:4355451|PMID:19667090) BHF-UCL PMID:19667090 MGI:4355451 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918 		JBrowse link
G Mink1 misshapen like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) MGI PMID:15608642 NCBI chrNW_004955467:10,256,722...10,312,011
Ensembl chrNW_004955467:10,256,434...10,313,834 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8666928) MGI PMID:8666928 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISO (MGI:3834308|PMID:17227833) BHF-UCL PMID:17227833 MGI:3834308 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chrNW_004955493:7,256,505...7,258,607 JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase 70kDa acts_upstream_of_or_within ISO (PMID:7630421) MGI PMID:7630421 NCBI chrNW_004955470:4,379,260...4,397,851
Ensembl chrNW_004955470:4,386,311...4,396,419 		JBrowse link
positive regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:17210642) MGI PMID:17210642 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger involved_in ISO (MGI:3615850|PMID:15964995) HGNC-UCL PMID:15964995 MGI:3615850 NCBI chrNW_004955429:6,548,586...6,553,730
Ensembl chrNW_004955429:6,547,731...6,558,105 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16230479) MGI PMID:16230479 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:8590311 RGD:7401228 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098) MGI PMID:11894098 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISO (MGI:3029054|PMID:14764698), (MGI:3847177|PMID:19273836) BHF-UCL PMID:14764698 PMID:19273836 MGI:3029054 MGI:3847177 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
positive regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:11067867), (PMID:16670300)
(PMID:11435465)
(PMID:11067867), (PMID:12163459), (PMID:16670300)		 MGI PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:4836302|PMID:20856819) BHF-UCL PMID:20856819 MGI:4836302 NCBI chrNW_004955477:10,894,288...10,906,961
Ensembl chrNW_004955477:10,895,446...10,907,215 		JBrowse link
G Egr3 early growth response 3 acts_upstream_of_or_within ISO (PMID:21737317) MGI PMID:21737317 NCBI chrNW_004955403:46,105,447...46,108,149
Ensembl chrNW_004955403:46,105,447...46,108,149 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) BHF-UCL PMID:19109233 MGI:3836494 NCBI chrNW_004955453:14,376,665...14,382,536
Ensembl chrNW_004955453:14,376,718...14,381,747 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO (PMID:9916699)
(PMID:9252128)		 MGI PMID:9252128 PMID:9916699 NCBI chrNW_004955475:10,676,592...10,680,565
Ensembl chrNW_004955475:10,676,870...10,680,517 		JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO (PMID:9215626) MGI PMID:9215626 NCBI chrNW_004955426:20,785,896...20,818,512
Ensembl chrNW_004955426:20,787,471...20,818,577 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (MGI:1891792|PMID:11017103) CACAO PMID:11017103 MGI:1891792 NCBI chrNW_004955416:5,494,030...5,561,608
Ensembl chrNW_004955416:5,494,030...5,561,614 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) BHF-UCL PMID:19109233 MGI:3836494 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 involved_in ISO (MGI:5432321|PMID:22561606) UniProt PMID:22561606 MGI:5432321 NCBI chrNW_004955458:2,084,931...2,108,328
Ensembl chrNW_004955458:2,084,868...2,108,335 		JBrowse link
G Vnn1 vanin 1 involved_in ISO (MGI:84472|PMID:8934567) BHF-UCL PMID:8934567 MGI:84472 NCBI chrNW_004955436:13,238,307...13,266,800
Ensembl chrNW_004955436:13,238,603...13,259,577 		JBrowse link
positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd3d CD3d molecule involved_in ISO (MGI:87267|PMID:9135151) UniProt PMID:9135151 MGI:87267 NCBI chrNW_004955412:19,481,059...19,484,890
Ensembl chrNW_004955412:19,480,977...19,484,721 		JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO (PMID:7679955), (PMID:8598040)
(PMID:9432982)		 MGI PMID:7679955 PMID:8598040 PMID:9432982 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826 		JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO (PMID:12871644) MGI PMID:12871644 NCBI chrNW_004955408:22,630,375...23,059,832
Ensembl chrNW_004955408:22,630,364...23,059,899 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO (PMID:15064401) MGI PMID:15064401 NCBI chrNW_004955489:726,641...814,180
Ensembl chrNW_004955489:725,759...814,180 		JBrowse link
G LOC102023843 HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (PMID:8598040)
(PMID:8598041), (PMID:9432982)
(PMID:8638109)		 MGI PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chrNW_004955437:1,558,806...1,562,294
Ensembl chrNW_004955437:1,558,911...1,562,162 		JBrowse link
G Nfatc3 nuclear factor of activated T cells 3 involved_in ISO (MGI:3820023|PMID:17579027) UniProt PMID:17579027 MGI:3820023 NCBI chrNW_004955484:8,433,765...8,558,005
Ensembl chrNW_004955484:8,436,330...8,526,680 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8666928) MGI PMID:8666928 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISO (MGI:3834308|PMID:17227833) BHF-UCL PMID:17227833 MGI:3834308 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO (PMID:21098124) MGI PMID:21098124 NCBI chrNW_004955437:9,100,546...9,109,305
Ensembl chrNW_004955437:9,098,968...9,107,057 		JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO (PMID:21487392) MGI PMID:21487392 NCBI chrNW_004955495:6,678,195...6,699,408
Ensembl chrNW_004955495:6,678,195...6,699,058 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase 70kDa acts_upstream_of_or_within ISO (PMID:7630421) MGI PMID:7630421 NCBI chrNW_004955470:4,379,260...4,397,851
Ensembl chrNW_004955470:4,386,311...4,396,419 		JBrowse link
regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf9 TNF receptor superfamily member 9 acts_upstream_of_or_within ISO (PMID:8405064) MGI PMID:8405064 NCBI chrNW_004955486:4,986,245...5,009,437
Ensembl chrNW_004955486:4,989,582...5,010,213 		JBrowse link
G Tnfsf9 TNF superfamily member 9 acts_upstream_of_or_within ISO (PMID:8405064) MGI PMID:8405064 NCBI chrNW_004955495:3,101,965...3,107,552 JBrowse link
regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxn1 forkhead box N1 involved_in ISO (MGI:5554515|PMID:24184560) UniProt PMID:24184560 MGI:5554515 NCBI chrNW_004955481:4,611,246...4,640,606
Ensembl chrNW_004955481:4,611,087...4,627,113 		JBrowse link
G Tox thymocyte selection associated high mobility group box involved_in ISO (MGI:3773459|PMID:18195075) UniProt PMID:18195075 MGI:3773459 NCBI chrNW_004955444:19,453,789...19,796,419
Ensembl chrNW_004955444:19,453,783...19,795,167 		JBrowse link
regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO RGD PMID:3876160 RGD:152995412 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor involved_in ISO (MGI:4849324|PMID:21048919) BHF-UCL PMID:21048919 MGI:4849324 NCBI chrNW_004955528:1,753,450...1,759,886
Ensembl chrNW_004955528:1,753,450...1,759,886 		JBrowse link
G Ankle1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (MGI:5800654|PMID:27010503) UniProt PMID:27010503 MGI:5800654 NCBI chrNW_004955524:933,200...936,933 JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking involved_in ISO (MGI:1095293|PMID:9218588) BHF-UCL PMID:9218588 MGI:1095293 NCBI chrNW_004955555:2,029,591...2,056,321
Ensembl chrNW_004955555:2,029,546...2,058,497 		JBrowse link
G Foxn1 forkhead box N1 acts_upstream_of_or_within ISO (PMID:22072979) MGI PMID:22072979 NCBI chrNW_004955481:4,611,246...4,640,606
Ensembl chrNW_004955481:4,611,087...4,627,113 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:24043312) MGI PMID:24043312 NCBI chrNW_004955441:6,649,895...6,724,271
Ensembl chrNW_004955441:6,646,385...6,713,028 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 acts_upstream_of_or_within ISO (PMID:24043312) MGI PMID:24043312 NCBI chrNW_004955409:12,542,353...12,622,165
Ensembl chrNW_004955409:12,542,401...12,620,971 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 acts_upstream_of_or_within ISO (PMID:9126927)
(PMID:9389660)		 MGI PMID:9126927 PMID:9389660 NCBI chrNW_004955429:23,011,627...23,198,188
Ensembl chrNW_004955429:23,010,790...23,198,250 		JBrowse link
thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family member 11 acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:14670303) MGI PMID:14670303 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO (PMID:14517551) MGI PMID:14517551 NCBI chrNW_004955489:726,641...814,180
Ensembl chrNW_004955489:725,759...814,180 		JBrowse link
G Jag2 jagged canonical Notch ligand 2 involved_in ISO (PMID:10383933) UniProt PMID:10383933 NCBI chrNW_004955538:3,421,685...3,433,829
Ensembl chrNW_004955538:3,421,685...3,433,842 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase 70kDa acts_upstream_of_or_within ISO (PMID:9208839) MGI PMID:9208839 NCBI chrNW_004955470:4,379,260...4,397,851
Ensembl chrNW_004955470:4,386,311...4,396,419 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12362
    immune system process 1980
      leukocyte activation 888
        lymphocyte activation 720
          lymphocyte differentiation 394
            T cell differentiation 293
              T cell differentiation in thymus 101
                DN2 thymocyte differentiation 4
                DN3 thymocyte differentiation 1
                DN4 thymocyte differentiation 4
                immature T cell proliferation in thymus + 15
                negative regulation of T cell differentiation in thymus + 11
                positive regulation of T cell differentiation in thymus + 10
                regulation of T cell differentiation in thymus + 28
                thymic T cell selection + 26
Path 2
Term Annotations click to browse term
  biological_process 12362
    developmental process 5862
      cellular developmental process 3880
        cell differentiation 3879
          cell development 2838
            hemopoiesis 920
              leukocyte differentiation 592
                mononuclear cell differentiation 483
                  lymphocyte differentiation 394
                    T cell differentiation 293
                      T cell differentiation in thymus 101
                        DN2 thymocyte differentiation 4
                        DN3 thymocyte differentiation 1
                        DN4 thymocyte differentiation 4
                        immature T cell proliferation in thymus + 15
                        negative regulation of T cell differentiation in thymus + 11
                        positive regulation of T cell differentiation in thymus + 10
                        regulation of T cell differentiation in thymus + 28
                        thymic T cell selection + 26
paths to the root