Mink1 (misshapen like kinase 1) - Rat Genome Database

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Gene: Mink1 (misshapen like kinase 1) Chinchilla lanigera
Analyze
Symbol: Mink1
Name: misshapen like kinase 1
RGD ID: 8963540
Description: ENCODES a protein that exhibits ATP binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); brain development (ortholog); chemical synaptic transmission (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 1A (ortholog); FOUND IN cytoplasm (ortholog); glutamatergic synapse (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: misshapen-like kinase 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,256,434 - 10,313,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,256,722 - 10,312,011 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mink1Chinchillaautistic disorder  ISOMINK1 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:25741868
Mink1Chinchillacongenital myasthenic syndrome  ISOMINK1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10496269 more ...
Mink1Chinchillacongenital myasthenic syndrome 1A  ISOMINK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital myasthenic syndrome 1AClinVarPMID:10496269 more ...
Mink1Chinchillacongenital myasthenic syndrome 4A  ISOMINK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital myasthenic syndrome 4AClinVarPMID:10496269 more ...
Mink1Chinchillacongenital myasthenic syndrome 4B  ISOMINK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital myasthenic syndrome 4BClinVarPMID:10496269 more ...
Mink1Chinchillacongenital myasthenic syndrome 4C  ISOMINK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital myasthenic syndrome 4CClinVarPMID:10496269 more ...


Biological Process
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mink1Chinchillaactin cytoskeleton organization involved_inISOMINK1 (Homo sapiens)9068941 PMID:15469942UniProtPMID:15469942
Mink1Chinchillabrain development involved_inISOMink1 (Mus musculus)9068941 PMID:10708748UniProtPMID:10708748
Mink1Chinchillachemical synaptic transmission involved_inISOMink1 (Rattus norvegicus)9068941PMID:21048137UniProtPMID:21048137 and REF_RGD_ID:8553980
Mink1Chinchilladendrite morphogenesis involved_inISOMink1 (Rattus norvegicus)9068941PMID:21048137UniProtPMID:21048137 and REF_RGD_ID:8553980
Mink1Chinchillamicrovillus assembly NOT|involved_inISOMINK1 (Homo sapiens)9068941 PMID:22797597UniProtPMID:22797597
Mink1Chinchillanegative thymic T cell selection acts_upstream_of_or_withinISOMink1 (Mus musculus)9068941 PMID:15608642MGIPMID:15608642
Mink1Chinchillaneuron cellular homeostasis involved_inISOMink1 (Rattus norvegicus)9068941PMID:21048137CACAOPMID:21048137 and REF_RGD_ID:8553980
Mink1Chinchillapositive regulation of JNK cascade involved_inISOMINK1 (Homo sapiens)9068941 PMID:15469942UniProtPMID:15469942
Mink1Chinchillapositive regulation of JNK cascade involved_inISOMink1 (Mus musculus)9068941 PMID:10708748UniProtPMID:10708748
Mink1Chinchillapositive regulation of p38MAPK cascade involved_inISOMink1 (Mus musculus)9068941 PMID:10708748UniProtPMID:10708748
Mink1Chinchillaprotein autophosphorylation involved_inISOMINK1 (Homo sapiens)9068941 PMID:15469942UniProtPMID:15469942
Mink1Chinchillaprotein phosphorylation involved_inISOMINK1 (Homo sapiens)9068941 PMID:21690388CACAOPMID:21690388
Mink1Chinchillaprotein phosphorylation involved_inISOMink1 (Mus musculus)9068941 PMID:10708748UniProtPMID:10708748
Mink1Chinchillaregulation of AMPA receptor activity involved_inISOMink1 (Rattus norvegicus)9068941PMID:21048137UniProtPMID:21048137 and REF_RGD_ID:8553980
Mink1Chinchillaregulation of cell migration involved_inISOMINK1 (Homo sapiens)9068941 PMID:15469942UniProtPMID:15469942
Mink1Chinchillaregulation of cell-cell adhesion involved_inISOMINK1 (Homo sapiens)9068941 PMID:15469942UniProtPMID:15469942
Mink1Chinchillaregulation of cell-matrix adhesion involved_inISOMINK1 (Homo sapiens)9068941 PMID:15469942UniProtPMID:15469942
Mink1Chinchillaregulation of postsynapse organization involved_inISOMink1 (Rattus norvegicus)9068941PMID:21048137SynGOPMID:21048137 and REF_RGD_ID:8553980
1 to 18 of 18 rows

Cellular Component

  


#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074  



Mink1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,256,434 - 10,313,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,256,722 - 10,312,011 (+)NCBIChiLan1.0ChiLan1.0
MINK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38174,833,340 - 4,898,061 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl174,833,340 - 4,898,061 (+)EnsemblGRCh38hg38GRCh38
GRCh37174,736,635 - 4,801,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36174,683,351 - 4,742,135 (+)NCBINCBI36Build 36hg18NCBI36
Celera174,751,747 - 4,816,237 (+)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef174,624,721 - 4,689,491 (+)NCBIHuRef
CHM1_1174,745,647 - 4,810,633 (+)NCBICHM1_1
T2T-CHM13v2.0174,722,898 - 4,788,313 (+)NCBIT2T-CHM13v2.0
Mink1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,452,272 - 70,505,309 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,453,707 - 70,505,309 (+)EnsemblGRCm39 Ensembl
GRCm381170,561,580 - 70,614,482 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,562,881 - 70,614,483 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,376,383 - 70,427,984 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,379,085 - 70,430,673 (+)NCBIMGSCv36mm8
Celera1178,111,189 - 78,162,803 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1143.0NCBI
Mink1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,776,879 - 55,829,406 (+)NCBIGRCr8
mRatBN7.21055,278,293 - 55,330,782 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1055,278,391 - 55,330,782 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,958,877 - 60,011,540 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01059,447,383 - 59,500,046 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,946,491 - 54,999,149 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01057,185,310 - 57,238,531 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,185,347 - 57,238,531 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,930,810 - 56,984,074 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,443,253 - 57,496,763 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11057,507,528 - 57,510,382 (+)NCBI
Celera1054,424,066 - 54,476,447 (+)NCBICelera
Cytogenetic Map10q24NCBI
MINK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21912,441,492 - 12,506,241 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11714,409,955 - 14,474,570 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0174,879,851 - 4,944,374 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1174,868,625 - 4,932,789 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl174,868,620 - 4,932,789 (+)Ensemblpanpan1.1panPan2
MINK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1531,707,975 - 31,718,013 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl531,708,553 - 31,749,842 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha531,847,635 - 31,889,644 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0531,813,049 - 31,855,271 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl531,813,030 - 31,855,277 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1531,779,569 - 31,821,588 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0531,739,278 - 31,781,273 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0531,915,651 - 31,957,663 (-)NCBIUU_Cfam_GSD_1.0
Mink1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560253,036,609 - 53,087,076 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366772,813,899 - 2,864,366 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366772,813,899 - 2,864,366 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MINK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,016,299 - 52,066,693 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,016,297 - 52,066,687 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,085,255 - 54,102,452 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MINK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,305,680 - 4,370,554 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,305,701 - 4,369,780 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,152 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mink1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247868,711,263 - 8,763,343 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247868,711,388 - 8,764,102 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000014707   ⟹   ENSCLAP00000014549
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,256,434 - 10,313,834 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000014708   ⟹   ENSCLAP00000014550
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,256,434 - 10,311,265 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000014709   ⟹   ENSCLAP00000014551
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,256,726 - 10,312,011 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000014710   ⟹   ENSCLAP00000014552
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,256,727 - 10,312,011 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000014711   ⟹   ENSCLAP00000014553
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,257,044 - 10,311,265 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000014712   ⟹   ENSCLAP00000014554
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546710,292,605 - 10,311,265 (+)Ensembl
RefSeq Acc Id: XM_005399604   ⟹   XP_005399661
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,726 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005399605   ⟹   XP_005399662
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,731 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005399607   ⟹   XP_005399664
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,730 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005399608   ⟹   XP_005399665
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,727 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005399609   ⟹   XP_005399666
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,731 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522166   ⟹   XP_013377620
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,724 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522167   ⟹   XP_013377621
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,722 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522168   ⟹   XP_013377622
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,727 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522169   ⟹   XP_013377623
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,722 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522170   ⟹   XP_013377624
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,728 - 10,312,011 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522171   ⟹   XP_013377625
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546710,256,723 - 10,312,011 (+)NCBI
Sequence:
1 to 5 of 17 rows
1 to 5 of 17 rows
RefSeq Acc Id: XP_005399661   ⟸   XM_005399604
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VLF6 (UniProtKB/TrEMBL),   A0A8C2VKD3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005399665   ⟸   XM_005399608
- Peptide Label: isoform X10
- UniProtKB: A0A8C2VH30 (UniProtKB/TrEMBL),   A0A8C2VEY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005399662   ⟸   XM_005399605
- Peptide Label: isoform X7
- UniProtKB: A0A8C2VGP7 (UniProtKB/TrEMBL),   A0A8C2VKD3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005399666   ⟸   XM_005399609
- Peptide Label: isoform X11
- UniProtKB: A0A8C2VEY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005399664   ⟸   XM_005399607
- Peptide Label: isoform X9
- UniProtKB: A0A8C2VKD3 (UniProtKB/TrEMBL)
- Sequence:
CNH   Protein kinase



1 to 38 of 38 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000010046 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014707 ENTREZGENE
  ENSCLAT00000014707.1 UniProtKB/TrEMBL
  ENSCLAT00000014708 ENTREZGENE
  ENSCLAT00000014708.1 UniProtKB/TrEMBL
  ENSCLAT00000014709 ENTREZGENE
  ENSCLAT00000014709.1 UniProtKB/TrEMBL
  ENSCLAT00000014710 ENTREZGENE
  ENSCLAT00000014710.1 UniProtKB/TrEMBL
  ENSCLAT00000014711.1 UniProtKB/TrEMBL
  ENSCLAT00000014712 ENTREZGENE
  ENSCLAT00000014712.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CNH_dom UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  STE20_Ser-Thr_kinase UniProtKB/TrEMBL
NCBI Gene Mink1 ENTREZGENE
PANTHER CNH DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MISSHAPEN LIKE KINASE 1 UniProtKB/TrEMBL
Pfam CNH UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE CNH UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART CNH UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VEY0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VGP7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VH30 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VIU3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VKD3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VLF6 ENTREZGENE, UniProtKB/TrEMBL
1 to 38 of 38 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Mink1  misshapen like kinase 1    misshapen-like kinase 1  Symbol and/or name change 5135510 APPROVED