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Gene: Mink1 (misshapen-like kinase 1 (zebrafish)) Mus musculus
Symbol: Mink1
Name: misshapen-like kinase 1 (zebrafish)
Description: Exhibits ATP binding activity and protein serine/threonine kinase activity. Involved in negative thymic T cell selection; positive regulation of stress-activated MAPK cascade; and protein phosphorylation. Predicted to localize to Golgi apparatus. Orthologous to human MINK1 (misshapen like kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B55; GCK family kinase MiNK; Map4k6; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MINK; misshapen-like kinase 1; misshapen/NIK-related kinase; Misshapen/NIKs-related kinase; RP23-122P1.6; Yeast Sps1/Ste20-related kinase 2; Ysk2
Homo sapiens (human) : MINK1 (misshapen like kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mink1 (misshapen-like kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mink1 (misshapen like kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MINK1 (misshapen like kinase 1)
Canis lupus familiaris (dog) : MINK1 (misshapen like kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mink1 (misshapen like kinase 1)
Sus scrofa (pig) : MINK1 (misshapen like kinase 1)
Chlorocebus sabaeus (African green monkey) : MINK1 (misshapen like kinase 1)
Heterocephalus glaber (naked mole-rat) : Mink1 (misshapen like kinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1170,562,881 - 70,614,483 (+)EnsemblGRCm38mm10GRCm38
GRCm381170,561,580 - 70,614,482 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371170,376,383 - 70,427,984 (+)NCBIGRCm37mm9NCBIm37
MGSCv361170,379,085 - 70,430,673 (+)NCBImm8
Celera1178,111,189 - 78,162,803 (+)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mink1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1622349
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.