MINK1 (misshapen like kinase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: MINK1 (misshapen like kinase 1) Chlorocebus sabaeus
Analyze
Symbol: MINK1
Name: misshapen like kinase 1
RGD ID: 18669048
Description: ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); brain development (ortholog); chemical synaptic transmission (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 1A (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: misshapen-like kinase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,305,680 - 4,370,554 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,305,701 - 4,369,780 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,152 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
MINK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,305,680 - 4,370,554 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,305,701 - 4,369,780 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,152 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MINK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38174,833,340 - 4,898,061 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl174,833,340 - 4,898,061 (+)EnsemblGRCh38hg38GRCh38
GRCh37174,736,635 - 4,801,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36174,683,351 - 4,742,135 (+)NCBINCBI36Build 36hg18NCBI36
Celera174,751,747 - 4,816,237 (+)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef174,624,721 - 4,689,491 (+)NCBIHuRef
CHM1_1174,745,647 - 4,810,633 (+)NCBICHM1_1
T2T-CHM13v2.0174,722,898 - 4,788,313 (+)NCBIT2T-CHM13v2.0
Mink1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,452,272 - 70,505,309 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,453,707 - 70,505,309 (+)EnsemblGRCm39 Ensembl
GRCm381170,561,580 - 70,614,482 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,562,881 - 70,614,483 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,376,383 - 70,427,984 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,379,085 - 70,430,673 (+)NCBIMGSCv36mm8
Celera1178,111,189 - 78,162,803 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1143.0NCBI
Mink1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,776,879 - 55,829,406 (+)NCBIGRCr8
mRatBN7.21055,278,293 - 55,330,782 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1055,278,391 - 55,330,782 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,958,877 - 60,011,540 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01059,447,383 - 59,500,046 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,946,491 - 54,999,149 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01057,185,310 - 57,238,531 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,185,347 - 57,238,531 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,930,810 - 56,984,074 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,443,253 - 57,496,763 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11057,507,528 - 57,510,382 (+)NCBI
Celera1054,424,066 - 54,476,447 (+)NCBICelera
Cytogenetic Map10q24NCBI
Mink1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,256,434 - 10,313,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,256,722 - 10,312,011 (+)NCBIChiLan1.0ChiLan1.0
MINK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21912,441,492 - 12,506,241 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11714,409,955 - 14,474,570 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0174,879,851 - 4,944,374 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1174,868,625 - 4,932,789 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl174,868,620 - 4,932,789 (+)Ensemblpanpan1.1panPan2
MINK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1531,707,975 - 31,718,013 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl531,708,553 - 31,749,842 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha531,847,635 - 31,889,644 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0531,813,049 - 31,855,271 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl531,813,030 - 31,855,277 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1531,779,569 - 31,821,588 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0531,739,278 - 31,781,273 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0531,915,651 - 31,957,663 (-)NCBIUU_Cfam_GSD_1.0
Mink1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560253,036,609 - 53,087,076 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366772,813,899 - 2,864,366 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366772,813,899 - 2,864,366 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MINK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,016,299 - 52,066,693 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,016,297 - 52,066,687 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,085,255 - 54,102,452 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Mink1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247868,711,263 - 8,763,343 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247868,711,388 - 8,764,102 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 2 60
Low 18
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008009962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008009976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000011095   ⟹   ENSCSAP00000009177
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl164,305,701 - 4,369,780 (+)Ensembl
RefSeq Acc Id: XM_008009962   ⟹   XP_008008153
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,680 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009963   ⟹   XP_008008154
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,680 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009964   ⟹   XP_008008155
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,680 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009965   ⟹   XP_008008156
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,680 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009966   ⟹   XP_008008157
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,680 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009967   ⟹   XP_008008158
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,681 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009968   ⟹   XP_008008159
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,681 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009969   ⟹   XP_008008160
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,681 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009971   ⟹   XP_008008162
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,681 - 4,370,554 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,913 - 17,331,152 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009972   ⟹   XP_008008163
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,680 - 4,370,551 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009973   ⟹   XP_008008164
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,681 - 4,370,554 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,913 - 17,331,152 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009974   ⟹   XP_008008165
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,681 - 4,370,554 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,913 - 17,331,152 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008009976   ⟹   XP_008008167
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1164,305,681 - 4,370,554 (+)NCBI
Vero_WHO_p1.0NW_02366605917,264,913 - 17,331,152 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037987422   ⟹   XP_037843350
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
RefSeq Acc Id: XM_037987424   ⟹   XP_037843352
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,144 (-)NCBI
RefSeq Acc Id: XM_037987425   ⟹   XP_037843353
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
RefSeq Acc Id: XM_037987426   ⟹   XP_037843354
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605917,264,905 - 17,331,147 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008008153   ⟸   XM_008009962
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008008154   ⟸   XM_008009963
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008008156   ⟸   XM_008009965
- Peptide Label: isoform X4
RefSeq Acc Id: XP_008008157   ⟸   XM_008009966
- Peptide Label: isoform X6
RefSeq Acc Id: XP_008008155   ⟸   XM_008009964
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008008163   ⟸   XM_008009972
- Peptide Label: isoform X13
RefSeq Acc Id: XP_008008162   ⟸   XM_008009971
- Peptide Label: isoform X11
RefSeq Acc Id: XP_008008165   ⟸   XM_008009974
- Peptide Label: isoform X16
RefSeq Acc Id: XP_008008167   ⟸   XM_008009976
- Peptide Label: isoform X17
RefSeq Acc Id: XP_008008164   ⟸   XM_008009973
- Peptide Label: isoform X15
RefSeq Acc Id: XP_008008160   ⟸   XM_008009969
- Peptide Label: isoform X12
RefSeq Acc Id: XP_008008158   ⟸   XM_008009967
- Peptide Label: isoform X9
- UniProtKB: A0A0D9RKN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008008159   ⟸   XM_008009968
- Peptide Label: isoform X10
RefSeq Acc Id: ENSCSAP00000009177   ⟸   ENSCSAT00000011095
RefSeq Acc Id: XP_037843353   ⟸   XM_037987425
- Peptide Label: isoform X8
RefSeq Acc Id: XP_037843354   ⟸   XM_037987426
- Peptide Label: isoform X14
RefSeq Acc Id: XP_037843350   ⟸   XM_037987422
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037843352   ⟸   XM_037987424
- Peptide Label: isoform X7


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013002 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011095.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CNH_dom UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene MINK1 ENTREZGENE
PANTHER CNH DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MISSHAPEN LIKE KINASE 1 UniProtKB/TrEMBL
Pfam CNH UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE CNH UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART CNH UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0D9RKN8 ENTREZGENE, UniProtKB/TrEMBL