.
wide pore channel activity - Ontology Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:wide pore channel activity
go back to main search page
Accession:GO:0022829 term browser browse the term
Definition:Enables the energy-independent facilitated diffusion of propanediol through a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.
Synonyms:exact_synonym: non-gated, wide pore channel activity
 narrow_synonym: gap junction activity

 Loading Annotations... 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
X

show annotations for term's descendants           Sort by:
wide pore channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsdma gasdermin A enables ISO
IEA		 (PMID:35110732), (PMID:35545676)
GO_REF:0000107		 RGD
Ensembl		 PMID:35110732 PMID:35545676 GO_REF:0000107 NCBI chr10:84,110,590...84,135,804
Ensembl chr10:83,627,051...83,639,543 		JBrowse link
G Gsdmc gasdermin C enables ISO (PMID:32929201), (PMID:34012073) RGD PMID:32929201 PMID:34012073 NCBI chr 7:95,594,015...95,606,106
Ensembl chr 7:95,594,015...95,611,344 		JBrowse link
G Gsdmd gasdermin D enables ISO
IEA		 (PMID:32109412)
GO_REF:0000107
(PMID:35749514), (PMID:35794369)
(PMID:32820063), (PMID:38538834)
(PMID:27339137), (PMID:38632402)
(PMID:27383986), (PMID:29195811), (PMID:29274245), (PMID:33883744), (PMID:35705808)
(PMID:32820063), (PMID:38040708), (PMID:38530158), (PMID:38599239)
(PMID:35794369)
(PMID:33883744)		 RGD
Ensembl		 PMID:27339137 PMID:27383986 PMID:29195811 PMID:29274245 PMID:32109412 More... GO_REF:0000107 NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsdme gasdermin E enables ISO
IEA		 (PMID:28459430)
GO_REF:0000107
(PMID:32188940), (PMID:33852854), (PMID:35594856)		 RGD
Ensembl		 PMID:28459430 PMID:32188940 PMID:33852854 PMID:35594856 GO_REF:0000107 NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Mpeg1 macrophage expressed 1 enables ISS
ISO		 GO_REF:0000024
(PMID:32064340), (PMID:36245269), (PMID:37347855)
(PMID:31537793)		 UniProt
RGD		 PMID:31537793 PMID:32064340 PMID:36245269 PMID:37347855 GO_REF:0000024 NCBI chr 1:218,876,848...218,881,364
Ensembl chr 1:209,452,133...209,458,855 		JBrowse link
G Panx1 Pannexin 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Panx2 pannexin 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:122,018,937...122,032,009
Ensembl chr 7:120,139,294...120,152,361 		JBrowse link
G Panx3 pannexin 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:37,366,758...37,377,640
Ensembl chr 8:37,366,862...37,377,640 		JBrowse link
G Prf1 perforin 1 enables ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:21037563), (PMID:26306037), (PMID:35148176), (PMID:35705808)
GO_REF:0000033
(PMID:20038786), (PMID:20889983), (PMID:24558045)
GO_REF:0000107		 UniProt
RGD
GO_Central
Ensembl		 PMID:20038786 PMID:20889983 PMID:21037563 PMID:24558045 PMID:26306037 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
gap junction channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein, alpha 1 enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:11397787), (PMID:15084279), (PMID:29366904)
(PMID:29366904)
(PMID:16790700), (PMID:1696265), (PMID:23348765)
PMID:15284189		 GO_Central
RGD		 PMID:1696265 PMID:11397787 PMID:15084279 PMID:16790700 PMID:23348765 More... GO_REF:0000033, RGD:1580399, RGD:1582674, RGD:12793029 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja10 gap junction protein, alpha 10 enables ISO
IEA
IBA		 (PMID:10329667)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10329667 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:51,787,407...51,799,827
Ensembl chr 5:46,992,946...46,996,570 		JBrowse link
G Gja3 gap junction protein, alpha 3 enables IDA
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:1659572 GO_REF:0000002 GO_REF:0000033, RGD:728416 NCBI chr15:35,296,946...35,322,405
Ensembl chr15:31,181,369...31,206,810 		JBrowse link
G Gja4 gap junction protein, alpha 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:139,633,287...139,635,925 		JBrowse link
G Gja5 gap junction protein, alpha 5 IDA RGD PMID:1328644 RGD:728713 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gja6 gap junction protein, alpha 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:33,840,689...33,845,585
Ensembl chr  X:33,840,549...33,845,614 		JBrowse link
G Gja8 gap junction protein, alpha 8 contributes_to
enables		 IDA
ISO		 (PMID:19756179) RGD PMID:19756179 PMID:16123426 RGD:1598965 NCBI chr 2:187,179,668...187,181,284
Ensembl chr 2:184,490,840...184,492,456 		JBrowse link
G Gjb1 gap junction protein, beta 1 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12119284 GO_REF:0000033, RGD:728476 NCBI chr  X:70,541,845...70,549,776
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Gjb2 gap junction protein, beta 2 enables TAS
IBA
ISO
ISS
IMP		 GO_REF:0000033
(PMID:15692151)
GO_REF:0000024
(PMID:12767933), (PMID:21094651)		 GO_Central
RGD
UniProt		 PMID:12767933 PMID:15692151 PMID:21094651 PMID:12064607 PMID:23232329 GO_REF:0000024 GO_REF:0000033, RGD:1299562, RGD:7349364 NCBI chr15:35,375,977...35,393,817
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Gjb3 gap junction protein, beta 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:144,933,692...144,939,435
Ensembl chr 5:139,649,195...139,654,980 		JBrowse link
G Gjb4 gap junction protein, beta 4 enables ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000002
GO_REF:0000033
(PMID:15692151)		 UniProt
InterPro
GO_Central
RGD		 PMID:15692151 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:144,948,231...144,964,014
Ensembl chr 5:139,675,780...139,679,667 		JBrowse link
G Gjb5 gap junction protein, beta 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:144,965,133...144,968,051
Ensembl chr 5:139,680,671...139,683,583 		JBrowse link
G Gjb6 gap junction protein, beta 6 enables ISO
IBA		 (PMID:12767933)
GO_REF:0000033		 RGD
GO_Central		 PMID:12767933 GO_REF:0000033 NCBI chr15:35,400,147...35,410,649
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Gjc1 gap junction protein, gamma 1 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11668048 GO_REF:0000033, RGD:628534 NCBI chr10:88,262,840...88,285,646
Ensembl chr10:87,760,528...87,785,867 		JBrowse link
G Gjc2 gap junction protein, gamma 2 enables ISO
IBA		 (PMID:11160382)
GO_REF:0000033		 RGD
GO_Central		 PMID:11160382 GO_REF:0000033 NCBI chr10:44,462,203...44,470,924
Ensembl chr10:43,962,642...43,970,467 		JBrowse link
G Gjc3 gap junction protein, gamma 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:16,899,846...16,912,309
Ensembl chr12:16,896,813...16,964,246 		JBrowse link
G Gjd2 gap junction protein, delta 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:121,226,372...121,229,367
Ensembl chr 3:100,772,062...100,775,061 		JBrowse link
G Gjd3 gap junction protein, delta 3 IMP RGD PMID:23385797 RGD:7364769 NCBI chr10:84,429,923...84,432,011
Ensembl chr10:83,934,135...83,934,971 		JBrowse link
G Gjd4 gap junction protein, delta 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:57,348,844...57,352,601
Ensembl chr17:57,349,877...57,352,446 		JBrowse link
G Gje1 gap junction protein, epsilon 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:10,905,890...10,911,800
Ensembl chr 1:9,086,348...9,088,138 		JBrowse link
G Panx1 Pannexin 1 IMP RGD PMID:14597722 RGD:1299639 NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Panx2 pannexin 2 IMP RGD PMID:14597722 RGD:1299639 NCBI chr 7:122,018,937...122,032,009
Ensembl chr 7:120,139,294...120,152,361 		JBrowse link
gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 enables ISO
IEA
IBA		 (PMID:16790700), (PMID:20606116), (PMID:23348765)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16790700 PMID:20606116 PMID:23348765 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 enables ISO
IEA		 (PMID:22247482)
GO_REF:0000107		 RGD
Ensembl		 PMID:22247482 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gjc1 gap junction protein, gamma 1 enables ISO (PMID:22982984) RGD PMID:22982984 NCBI chr10:88,262,840...88,285,646
Ensembl chr10:87,760,528...87,785,867 		JBrowse link
G Gjd3 gap junction protein, delta 3 enables IBA
ISO		 GO_REF:0000033
(PMID:22982984)		 GO_Central
RGD		 PMID:22982984 GO_REF:0000033 NCBI chr10:84,429,923...84,432,011
Ensembl chr10:83,934,135...83,934,971 		JBrowse link
gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 enables ISO
IEA		 (PMID:22247482)
GO_REF:0000107
(PMID:26786475)		 RGD
Ensembl		 PMID:22247482 PMID:26786475 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
gap junction channel activity involved in cardiac conduction electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 enables ISO
IEA		 (PMID:16790700), (PMID:23348765)
GO_REF:0000107		 RGD
Ensembl		 PMID:16790700 PMID:23348765 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
gap junction channel activity involved in cell communication by electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein, alpha 1 enables ISO (PMID:1696265) RGD PMID:1696265 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjb2 gap junction protein, beta 2 enables ISO (PMID:12767933) RGD PMID:12767933 NCBI chr15:35,375,977...35,393,817
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Gjb6 gap junction protein, beta 6 enables ISO (PMID:12767933) RGD PMID:12767933 NCBI chr15:35,400,147...35,410,649
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Gjc2 gap junction protein, gamma 2 enables ISO (PMID:17344063) RGD PMID:17344063 NCBI chr10:44,462,203...44,470,924
Ensembl chr10:43,962,642...43,970,467 		JBrowse link
gap junction hemi-channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein, alpha 1 enables ISS
ISO		 GO_REF:0000024
(PMID:29366904)		 UniProt
RGD		 PMID:29366904 GO_REF:0000024 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja3 gap junction protein, alpha 3 enables ISS
IDA
ISO		 GO_REF:0000024
PMID:17715132
(PMID:30044662)		 UniProt
RGD		 PMID:30044662 PMID:17715132 GO_REF:0000024, RGD:15090844 NCBI chr15:35,296,946...35,322,405
Ensembl chr15:31,181,369...31,206,810 		JBrowse link
G Gja5 gap junction protein, alpha 5 enables ISO
IEA		 (PMID:23348765)
GO_REF:0000107		 RGD
Ensembl		 PMID:23348765 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Panx1 Pannexin 1 NOT|enables IDA PMID:17715132 UniProt PMID:17715132 RGD:15090844 NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Panx2 pannexin 2 NOT|enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 7:122,018,937...122,032,009
Ensembl chr 7:120,139,294...120,152,361 		JBrowse link
G Panx3 pannexin 3 NOT|enables ISS
ISO		 GO_REF:0000024
(PMID:21690309)		 UniProt
RGD		 PMID:21690309 GO_REF:0000024 NCBI chr 8:37,366,758...37,377,640
Ensembl chr 8:37,366,862...37,377,640 		JBrowse link
porin activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07051831.1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 3:23,215,541...23,222,588 JBrowse link
G Bak1 BCL2-antagonist/killer 1 enables ISO
IEA		 (PMID:22006182)
GO_REF:0000107		 RGD
Ensembl		 PMID:22006182 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G ENSRNOG00000063023 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:246,631,795...246,632,409 JBrowse link
G ENSRNOG00000067316 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr13:2,022,739...2,023,266 JBrowse link
G ENSRNOG00000069396 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr  X:146,383,480...146,384,468 JBrowse link
G ENSRNOG00000069999 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 6:83,278,344...83,279,351 JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:88,486,745...88,498,833
Ensembl chr 1:79,358,786...79,370,915 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:2,512,214...2,526,105
Ensembl chr15:2,463,056...2,476,553 		JBrowse link
G Vdac3 voltage-dependent anion channel 3 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:76,137,489...76,153,933
Ensembl chr16:69,435,005...69,451,471 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    transporter activity 1395
      transmembrane transporter activity 1278
        passive transmembrane transporter activity 637
          channel activity 637
            wide pore channel activity 39
              gap junction channel activity + 23
              gap junction hemi-channel activity 6
              porin activity + 10
paths to the root