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ONTOLOGY REPORT - ANNOTATIONS

Term:pituitary gland development
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Accession:GO:0021983 term browser browse the term
Definition:The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
Synonyms:related_synonym: hypophysis development


show annotations for term's descendants           Sort by:
pituitary gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:18160680 RGD:2325274 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17180597 GO_REF:0000107 RGD:2306413 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866 		JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 ISO RGD PMID:17180597 RGD:2306413 NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,861,924...100,916,626 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9806931) Ensembl
MGI		 PMID:9806931 GO_REF:0000107 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17359964) Ensembl
MGI		 PMID:17359964 GO_REF:0000107 NCBI chr10:86,755,763...86,932,844
Ensembl chr10:86,755,786...86,932,825 		JBrowse link
G CDH1 cadherin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17373711 GO_REF:0000107 RGD:2289637 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16141355) Ensembl
MGI		 PMID:16141355 GO_REF:0000107 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor ISO RGD PMID:8946059 RGD:2313681 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11062007) Ensembl
MGI		 PMID:11062007 GO_REF:0000107 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G GATA2 GATA binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16543408) Ensembl
MGI		 PMID:16543408 GO_REF:0000107 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G GLI1 GLI family zinc finger 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10725236) Ensembl
MGI		 PMID:10725236 GO_REF:0000107 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:10725236) Ensembl
MGI
UniProt		 PMID:10725236 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:120,735,868...120,992,653
Ensembl chr 2:120,735,623...120,992,653 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17015435), (PMID:17426285)
(PMID:17426285)		 Ensembl
MGI		 PMID:17015435 PMID:17426285 GO_REF:0000107 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HESX1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IMP		 (PMID:20181723)
(PMID:11731482), (PMID:9620767)
(PMID:18775421)
(PMID:19093031)
(PMID:26781211)		 Ensembl
MGI
GO_Central
UniProt		 PMID:9620767 PMID:11731482 PMID:18775421 PMID:19093031 PMID:20181723 More... GO_REF:0000033 GO_REF:0000107 NCBI chr 3:57,197,838...57,227,615
Ensembl chr 3:57,197,838...57,227,606 		JBrowse link
G HMGA2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO (PMID:504232) MGI PMID:504232 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291 		JBrowse link
G INHBB inhibin subunit beta B involved_in ISO
IEA		 RGD
Ensembl		 PMID:18160680 GO_REF:0000107 RGD:2325274 NCBI chr 2:120,346,136...120,351,803
Ensembl chr 2:120,346,136...120,351,803 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9806931) Ensembl
MGI		 PMID:9806931 GO_REF:0000107 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730 		JBrowse link
G KDM1A lysine demethylase 1A acts_upstream_of_or_within ISO (PMID:17392792) MGI PMID:17392792 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18037398) Ensembl
MGI		 PMID:18037398 GO_REF:0000107 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128 		JBrowse link
G MSX1 msh homeobox 1 ISO RGD PMID:16451220 RGD:5132608 NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936 		JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9806931) Ensembl
MGI		 PMID:9806931 GO_REF:0000107 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149 		JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17359964) Ensembl
MGI		 PMID:17359964 GO_REF:0000107 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 involved_in NAS (PMID:15464421) UniProt PMID:15464421 NCBI chr  X:30,304,206...30,309,390
Ensembl chr  X:30,304,206...30,309,390 		JBrowse link
G PAX6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10588713) Ensembl
MGI		 PMID:10588713 GO_REF:0000107 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15208361 GO_REF:0000107 RGD:2308902 NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143 		JBrowse link
G PITX1 paired like homeodomain 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10049363) Ensembl
MGI		 PMID:10049363 GO_REF:0000107 NCBI chr 5:135,027,734...135,034,789
Ensembl chr 5:135,027,734...135,034,813 		JBrowse link
G PITX2 paired like homeodomain 2 acts_upstream_of_or_within ISO (PMID:10498698)
(PMID:10499586)		 MGI PMID:10498698 PMID:10499586 NCBI chr 4:110,617,423...110,642,123
Ensembl chr 4:110,617,423...110,642,123 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:16556738) MGI PMID:16556738 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584 		JBrowse link
G PROP1 PROP paired-like homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11731482) InterPro
MGI
Ensembl		 PMID:11731482 GO_REF:0000002 GO_REF:0000107 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17015435) Ensembl
MGI		 PMID:17015435 GO_REF:0000107 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEP (PMID:12065233) UniProt PMID:12065233 NCBI chr16:51,135,982...51,152,334
Ensembl chr16:51,135,982...51,152,334 		JBrowse link
G SIX3 SIX homeobox 3 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:18775421) UniProt
MGI		 PMID:18775421 GO_REF:0000024 NCBI chr 2:44,941,702...44,946,071
Ensembl chr 2:44,941,702...44,946,071 		JBrowse link
G SOX2 SRY-box transcription factor 2 involved_in IEP (PMID:18285410) UniProt PMID:18285410 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G SOX3 SRY-box transcription factor 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:140,502,985...140,505,069
Ensembl chr  X:140,502,985...140,505,069 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:8770891 GO_REF:0000107 RGD:4892048 NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539 		JBrowse link
G TBX19 T-box transcription factor 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11447259) Ensembl
MGI		 PMID:11447259 GO_REF:0000107 NCBI chr 1:168,280,877...168,314,426
Ensembl chr 1:168,280,877...168,314,426 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:17919533) MGI PMID:17919533 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678 		JBrowse link
adenohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:9140068) Ensembl
MGI
BHF-UCL		 PMID:9140068 GO_REF:0000024 GO_REF:0000107 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G GHRH growth hormone releasing hormone involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:15985453) BHF-UCL
MGI
Ensembl		 PMID:15985453 GO_REF:0000024 GO_REF:0000107 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,086...37,261,819 		JBrowse link
G GHRHR growth hormone releasing hormone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1270792), (PMID:1329576), (PMID:1504465) Ensembl
MGI		 PMID:1270792 PMID:1329576 PMID:1504465 GO_REF:0000107 NCBI chr 7:30,963,953...30,979,528
Ensembl chr 7:30,938,669...30,993,254 		JBrowse link
G GSX1 GS homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8631293) Ensembl
MGI		 PMID:8631293 GO_REF:0000107 NCBI chr13:27,792,483...27,794,768
Ensembl chr13:27,792,483...27,794,768 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18996108) Ensembl
MGI		 PMID:18996108 GO_REF:0000107 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G POU1F1 POU class 1 homeobox 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:16216912 GO_REF:0000107 RGD:1601440 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584 		JBrowse link
G PROP1 PROP paired-like homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18996108) Ensembl
MGI		 PMID:18996108 GO_REF:0000107 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9247269) Ensembl
MGI		 PMID:9247269 GO_REF:0000107 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G SOX2 SRY-box transcription factor 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16932809) RGD
Ensembl
MGI		 PMID:16932809 PMID:21815952 GO_REF:0000107 RGD:8661681 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
adenohypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOX2 dual oxidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17440044) Ensembl
MGI		 PMID:17440044 GO_REF:0000107 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172 		JBrowse link
corticotropin hormone secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:9463347) Ensembl
MGI
UniProt		 PMID:9463347 GO_REF:0000024 GO_REF:0000107 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G FGF2 fibroblast growth factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9463347) Ensembl
MGI		 PMID:9463347 GO_REF:0000107 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9463347) Ensembl
MGI		 PMID:9463347 GO_REF:0000107 NCBI chr10:101,770,109...101,780,369
Ensembl chr10:101,770,109...101,780,371 		JBrowse link
hypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PROP1 PROP paired-like homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16678101) Ensembl
MGI		 PMID:16678101 GO_REF:0000107 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15037319) Ensembl
MGI		 PMID:15037319 GO_REF:0000107 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
neurohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTP orthopedia homeobox involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10557207) Ensembl
MGI		 PMID:10557207 GO_REF:0000107 NCBI chr 5:77,628,712...77,638,713
Ensembl chr 5:77,628,712...77,638,713 		JBrowse link
G POU3F2 POU class 3 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8543156) Ensembl
MGI		 PMID:8543156 GO_REF:0000107 NCBI chr 6:98,834,574...98,839,458
Ensembl chr 6:98,834,574...98,839,458 		JBrowse link
prolactin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8638120) Ensembl
MGI		 PMID:8638120 GO_REF:0000107 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128 		JBrowse link
G PITX2 paired like homeodomain 2 involved_in TAS (PMID:10372733) BHF-UCL PMID:10372733 NCBI chr 4:110,617,423...110,642,123
Ensembl chr 4:110,617,423...110,642,123 		JBrowse link
somatotropin secreting cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRHR growth hormone releasing hormone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:6116352), (PMID:6194978) Ensembl
MGI		 PMID:6116352 PMID:6194978 GO_REF:0000107 NCBI chr 7:30,963,953...30,979,528
Ensembl chr 7:30,938,669...30,993,254 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:17015435) MGI PMID:17015435 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584 		JBrowse link
somatotropin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8638120) Ensembl
MGI		 PMID:8638120 GO_REF:0000107 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128 		JBrowse link
G PITX2 paired like homeodomain 2 involved_in TAS (PMID:10372733) BHF-UCL PMID:10372733 NCBI chr 4:110,617,423...110,642,123
Ensembl chr 4:110,617,423...110,642,123 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:1334535), (PMID:6194978) MGI PMID:1334535 PMID:6194978 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584 		JBrowse link
G PROP1 PROP paired-like homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:6194978) Ensembl
MGI		 PMID:6194978 GO_REF:0000107 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G WNT4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18351662) Ensembl
MGI		 PMID:18351662 GO_REF:0000107 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:9463347) UniProt
MGI
Ensembl		 PMID:9463347 GO_REF:0000024 GO_REF:0000107 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G FGF2 fibroblast growth factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9463347) Ensembl
MGI		 PMID:9463347 GO_REF:0000107 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9463347) Ensembl
MGI		 PMID:9463347 GO_REF:0000107 NCBI chr10:101,770,109...101,780,369
Ensembl chr10:101,770,109...101,780,371 		JBrowse link
G GATA2 GATA binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16543408) Ensembl
MGI		 PMID:16543408 GO_REF:0000107 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8638120) Ensembl
MGI		 PMID:8638120 GO_REF:0000107 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128 		JBrowse link
G WNT4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18351662) Ensembl
MGI		 PMID:18351662 GO_REF:0000107 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19715
    developmental process 7682
      anatomical structure development 7083
        diencephalon development 105
          pituitary gland development 50
            adenohypophysis development + 17
            hypophysis morphogenesis + 3
            neurohypophysis development + 2
Path 2
Term Annotations click to browse term
  biological_process 19715
    developmental process 7682
      anatomical structure development 7083
        multicellular organism development 5689
          system development 4964
            nervous system development 3089
              central nervous system development 1308
                brain development 953
                  forebrain development 570
                    diencephalon development 105
                      pituitary gland development 50
                        adenohypophysis development + 17
                        hypophysis morphogenesis + 3
                        neurohypophysis development + 2
paths to the root