FGF10 (fibroblast growth factor 10) - Rat Genome Database

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Gene: FGF10 (fibroblast growth factor 10) Homo sapiens
Analyze
Symbol: FGF10
Name: fibroblast growth factor 10
RGD ID: 734330
HGNC Page HGNC
Description: Enables heparin binding activity; receptor ligand activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including animal organ development; positive regulation of cell population proliferation; and positive regulation of intracellular signal transduction. Acts upstream of or within several processes, including fibroblast growth factor receptor signaling pathway involved in mammary gland specification; lung development; and positive regulation of urothelial cell proliferation. Located in several cellular components, including cell surface; extracellular space; and nucleus. Colocalizes with collagen-containing extracellular matrix. Implicated in LADD syndrome and aplasia of lacrimal and salivary glands.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FGF-10; keratinocyte growth factor 2; KGF-2; produced by fibroblasts of urinary bladder lamina propria
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl544,300,247 - 44,389,706 (-)EnsemblGRCh38hg38GRCh38
GRCh38544,300,247 - 44,389,706 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37544,300,349 - 44,389,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36544,340,854 - 44,424,541 (-)NCBINCBI36hg18NCBI36
Build 34544,340,853 - 44,424,541NCBI
Celera544,197,375 - 44,281,044 (-)NCBI
Cytogenetic Map5p12NCBI
HuRef544,258,055 - 44,341,703 (-)NCBIHuRef
CHM1_1544,306,497 - 44,390,196 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton reorganization  (IDA)
angiogenesis  (IEA,ISO)
animal organ formation  (IEA,ISO)
animal organ morphogenesis  (IBA,IEA,ISO)
blood vessel morphogenesis  (IEA,ISO)
blood vessel remodeling  (IEA,ISO)
branch elongation involved in salivary gland morphogenesis  (IEA,ISO)
branching involved in salivary gland morphogenesis  (IEA,ISO)
branching morphogenesis of an epithelial tube  (IDA)
bronchiole morphogenesis  (IEA,ISO)
bud elongation involved in lung branching  (IEA,ISO)
bud outgrowth involved in lung branching  (IDA)
cell differentiation  (IBA,IEA,ISO)
cell-cell signaling  (IEA,ISO)
chemotaxis  (IEA,ISO)
determination of left/right symmetry  (IEA,ISO)
digestive tract development  (IEA,ISO)
embryonic camera-type eye development  (IEA,ISO)
embryonic digestive tract development  (IEA,ISO)
embryonic digestive tract morphogenesis  (IEA,ISO)
embryonic genitalia morphogenesis  (IEA,ISO)
embryonic pattern specification  (IEA,ISO)
epidermis development  (IEA,ISO)
epidermis morphogenesis  (IEA,ISO)
epithelial cell differentiation  (IEA,ISO)
epithelial cell proliferation  (IDA)
epithelial cell proliferation involved in salivary gland morphogenesis  (IEA,ISO)
epithelial tube branching involved in lung morphogenesis  (IEA,ISO)
ERK1 and ERK2 cascade  (IDA)
establishment of mitotic spindle orientation  (IEA,ISO)
female genitalia morphogenesis  (IEA,ISO)
fibroblast growth factor receptor signaling pathway  (IBA,IEA)
fibroblast growth factor receptor signaling pathway involved in mammary gland specification  (IBA,IDA,IEA)
hair follicle morphogenesis  (IEA,ISO)
Harderian gland development  (IEA,ISO)
induction of positive chemotaxis  (IEA,ISO)
inner ear morphogenesis  (IEA,ISO)
lacrimal gland development  (IEA,IMP,ISO)
limb bud formation  (IEA,ISO)
limb development  (IBA,IEA,ISO)
limb morphogenesis  (IEA,ISO)
lung alveolus development  (IEA,ISO)
lung development  (IEA,ISO)
lung epithelium development  (IDA)
lung morphogenesis  (IEA,ISO)
lung proximal/distal axis specification  (IEA,ISO)
lung saccule development  (IMP)
male genitalia morphogenesis  (IEA,ISO)
mammary gland bud formation  (IEA,ISO)
mammary gland specification  (IEA,ISO)
mesenchymal cell differentiation involved in lung development  (IEA,ISO)
mesenchymal-epithelial cell signaling involved in lung development  (IEA,ISO)
mesonephros development  (IEP)
metanephros development  (IEP)
metanephros morphogenesis  (IEA,ISO)
muscle cell fate commitment  (IEA,ISO)
negative regulation of cell differentiation  (IEA,ISO)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IEA,ISO)
odontogenesis of dentin-containing tooth  (IEA,ISO)
organ growth  (IEA,ISO)
organ induction  (IEA,ISO)
otic vesicle formation  (IEA,ISO)
pancreas development  (IEA,ISO)
pituitary gland development  (IEA,ISO)
positive chemotaxis  (IBA,IDA,IEA)
positive regulation of ATP-dependent activity  (IDA)
positive regulation of canonical Wnt signaling pathway  (IBA,IEA,ISO)
positive regulation of cell population proliferation  (IBA,IEA,ISO)
positive regulation of DNA repair  (IDA)
positive regulation of epithelial cell migration  (IBA,IDA,IEA,ISO)
positive regulation of epithelial cell proliferation  (IBA,IDA,IEA,ISO)
positive regulation of epithelial cell proliferation involved in wound healing  (NAS)
positive regulation of ERK1 and ERK2 cascade  (IBA,IEA,ISO)
positive regulation of fibroblast proliferation  (IEA,ISO)
positive regulation of G1/S transition of mitotic cell cycle  (IDA)
positive regulation of gene expression  (IBA)
positive regulation of hair follicle cell proliferation  (IDA)
positive regulation of keratinocyte migration  (IDA)
positive regulation of keratinocyte proliferation  (IDA,IEA,ISO)
positive regulation of lymphocyte proliferation  (IDA)
positive regulation of MAPK cascade  (IDA)
positive regulation of mitotic cell cycle  (IEA,ISO)
positive regulation of Notch signaling pathway  (IEA,ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (IDA)
positive regulation of protein phosphorylation  (IBA)
positive regulation of Ras protein signal transduction  (IDA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of transcription, DNA-templated  (IEA)
positive regulation of urothelial cell proliferation  (IDA)
positive regulation of vascular endothelial growth factor receptor signaling pathway  (IEA,ISO)
positive regulation of white fat cell proliferation  (IEA,ISO)
positive regulation of Wnt signaling pathway  (IEA,ISO)
prostatic bud formation  (IEA,ISO)
protein localization to cell surface  (IDA)
radial glial cell differentiation  (IEA,ISS)
regulation of activin receptor signaling pathway  (IEA,ISO)
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling  (IEA,ISO)
regulation of cell migration  (IBA)
regulation of gene expression  (IEA,ISO)
regulation of saliva secretion  (IMP)
regulation of smoothened signaling pathway  (IEA,ISO)
respiratory system development  (IEA,ISO)
response to estradiol  (IEA,ISO)
response to lipopolysaccharide  (IEA,ISO)
response to organic cyclic compound  (IEA,ISO)
salivary gland development  (IMP)
salivary gland morphogenesis  (IEA,ISO)
secretion by lung epithelial cell involved in lung growth  (IBA,IDA)
semicircular canal fusion  (IEA,ISO)
semicircular canal morphogenesis  (IEA,ISO)
signal transduction  (IEA)
smooth muscle cell differentiation  (IEA,ISO)
somatic stem cell population maintenance  (IEA,ISO)
spleen development  (IEA,ISO)
submandibular salivary gland formation  (IEA,ISO)
tear secretion  (IMP)
thymus development  (IDA)
thyroid gland development  (IEA,ISO)
tissue regeneration  (IEA,ISO)
type II pneumocyte differentiation  (IEA,ISO)
urothelial cell proliferation  (IDA)
white fat cell differentiation  (IEA,ISO)
wound healing  (IBA,IDA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
2-3 finger syndactyly  (IAGP)
Abnormal facial shape  (IAGP)
Abnormal salivary gland morphology  (IAGP)
Absence of Stensen duct  (IAGP)
Absent lacrimal punctum  (IAGP)
Absent proximal phalanx of thumb  (IAGP)
Absent radius  (IAGP)
Absent thumb  (IAGP)
Alacrima  (IAGP)
Anosmia  (IAGP)
Aplasia of the parotid gland  (IAGP)
Arthritis  (IAGP)
Autosomal dominant inheritance  (IAGP)
Bicornuate uterus  (IAGP)
Bifid uvula  (IAGP)
Bilateral triphalangeal thumbs  (IAGP)
Broad forehead  (IAGP)
Broad hallux  (IAGP)
Carious teeth  (IAGP)
Choanal atresia  (IAGP)
Clinodactyly  (IAGP)
Clinodactyly of the 5th finger  (IAGP)
Conical incisor  (IAGP)
Corneal neovascularization  (IAGP)
Corneal perforation  (IAGP)
Corneal ulceration  (IAGP)
Coronal hypospadias  (IAGP)
Cryptorchidism  (IAGP)
Cupped ear  (IAGP)
Dacryocystitis  (IAGP)
Decreased corneal sensation  (IAGP)
Delayed eruption of primary teeth  (IAGP)
Downslanted palpebral fissures  (IAGP)
Duplication of thumb phalanx  (IAGP)
Dysphagia  (IAGP)
Enamel hypoplasia  (IAGP)
Epiphora  (IAGP)
Exotropia  (IAGP)
Finger syndactyly  (IAGP)
Global developmental delay  (IAGP)
Hydronephrosis  (IAGP)
Hyperextensible skin  (IAGP)
Hypertelorism  (IAGP)
Hypodontia  (IAGP)
Hypoplasia of the epiglottis  (IAGP)
Hypoplasia of the lacrimal punctum  (IAGP)
Hypoplasia of the radius  (IAGP)
Hypoplasia of the ulna  (IAGP)
Hypoplastic lacrimal duct  (IAGP)
Increased corneal thickness  (IAGP)
Keratoconjunctivitis sicca  (IAGP)
Lacrimal duct aplasia  (IAGP)
Lacrimal gland aplasia  (IAGP)
Lacrimal gland hypoplasia  (IAGP)
Limbal stem cell deficiency  (IAGP)
Low-set ears  (IAGP)
Microdontia  (IAGP)
Micrognathia  (IAGP)
Microtia  (IAGP)
Mixed hearing impairment  (IAGP)
Nail dysplasia  (IAGP)
Nasolacrimal duct obstruction  (IAGP)
Nephrosclerosis  (IAGP)
Open angle glaucoma  (IAGP)
Partial duplication of thumb phalanx  (IAGP)
Patent ductus arteriosus  (IAGP)
Periorbital fullness  (IAGP)
Preaxial polydactyly  (IAGP)
Ptosis  (IAGP)
Radial deviation of the 3rd finger  (IAGP)
Recurrent corneal erosions  (IAGP)
Renal agenesis  (IAGP)
Renal hypoplasia  (IAGP)
Scoliosis  (IAGP)
Seizure  (IAGP)
Short thumb  (IAGP)
Small thenar eminence  (IAGP)
Telecanthus  (IAGP)
Toe syndactyly  (IAGP)
Vesicoureteral reflux  (IAGP)
Xerostomia  (IAGP)
References

References - curated
1. Bless EP, etal., eNeuro. 2016 Sep 22;3(4). pii: eN-NWR-0027-16. doi: 10.1523/ENEURO.0027-16.2016. eCollection 2016 Jul-Aug.
2. Gambichler T, etal., BMC Dermatol. 2002 Apr 12;2:6. doi: 10.1186/1471-5945-2-6.
3. GOA_HUMAN data from the GO Consortium
4. Hamady ZZ, Ann R Coll Surg Engl. 2013 May;95(4):235-40. doi: 10.1308/003588413X13511609958217.
5. Hamady ZZ, etal., Gut. 2010 Apr;59(4):461-9. doi: 10.1136/gut.2008.176131. Epub 2009 Sep 7.
6. Hertzler-Schaefer K, etal., Cell Rep. 2014 Mar 13;6(5):818-26. doi: 10.1016/j.celrep.2014.01.045. Epub 2014 Feb 27.
7. Imaoka T, etal., J Radiat Res (Tokyo). 2008 Apr 16;.
8. Kelly RG, etal., Dev Cell 2001 Sep;1(3):435-40.
9. Miceli R, etal., J Pharmacol Exp Ther. 1999 Jul;290(1):464-71.
10. OMIM Disease Annotation Pipeline
11. Pipeline to import KEGG annotations from KEGG into RGD
12. Quantius J, etal., PLoS Pathog. 2016 Jun 20;12(6):e1005544. doi: 10.1371/journal.ppat.1005544. eCollection 2016 Jun.
13. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. RGD automated import pipeline for gene-chemical interactions
15. RGD automated import pipeline for human HPO-to-gene-to-disease annotations
16. Sautter NB, etal., Int J Pediatr Otorhinolaryngol. 2011 Nov;75(11):1368-71. doi: 10.1016/j.ijporl.2011.07.026. Epub 2011 Sep 1.
17. Sekine K, etal., Nat Genet 1999 Jan;21(1):138-41.
18. Soler PM, etal., Wound Repair Regen. 1999 May-Jun;7(3):172-8. doi: 10.1046/j.1524-475x.1999.00172.x.
19. Suzuki K, etal., FEBS Lett 2000 Sep 8;481(1):53-6.
20. Wu J, etal., J Biol Chem. 2019 Oct 11;294(41):15052-15067. doi: 10.1074/jbc.RA119.007404. Epub 2019 Aug 20.
21. Zhu YJ, etal., Toxicology. 2009 Jun 16;260(1-3):120-5. Epub 2009 Apr 5.
Additional References at PubMed
PMID:8622701   PMID:9287324   PMID:9582367   PMID:9740653   PMID:9927546   PMID:10541313   PMID:10579907   PMID:10629055   PMID:10951499   PMID:11286634   PMID:11294897   PMID:11896977  
PMID:11923311   PMID:12477932   PMID:12591959   PMID:12804770   PMID:12818887   PMID:14702039   PMID:14726452   PMID:14975937   PMID:15199049   PMID:15208658   PMID:15489334   PMID:15632068  
PMID:15654336   PMID:15679583   PMID:15690149   PMID:15806171   PMID:16086254   PMID:16323074   PMID:16344560   PMID:16501574   PMID:16597614   PMID:16597617   PMID:16630169   PMID:17071719  
PMID:17133345   PMID:17188682   PMID:17213838   PMID:17264867   PMID:17360555   PMID:17449030   PMID:17471512   PMID:17496316   PMID:17500053   PMID:17609292   PMID:17682060   PMID:17944804  
PMID:17959718   PMID:17969154   PMID:18081024   PMID:18199118   PMID:18329286   PMID:18437684   PMID:18454440   PMID:18587586   PMID:18594526   PMID:18773495   PMID:18990706   PMID:19102732  
PMID:19115389   PMID:19152659   PMID:19224135   PMID:19727229   PMID:19915940   PMID:20036575   PMID:20083228   PMID:20424473   PMID:20544801   PMID:20634891   PMID:20705941   PMID:21048031  
PMID:21310815   PMID:21696361   PMID:21742743   PMID:21743467   PMID:21873635   PMID:22303449   PMID:22877940   PMID:22965740   PMID:23169889   PMID:23328208   PMID:23599340   PMID:23774963  
PMID:23949615   PMID:23949743   PMID:24002438   PMID:24004862   PMID:24265547   PMID:24320134   PMID:24667918   PMID:24865969   PMID:25241761   PMID:25446127   PMID:26186194   PMID:26268776  
PMID:26511927   PMID:27339175   PMID:27411850   PMID:27503909   PMID:27640304   PMID:28514442   PMID:29053399   PMID:29372690   PMID:30021884   PMID:30639323   PMID:31021460   PMID:31574782  
PMID:31718875   PMID:32296183   PMID:32664970   PMID:32807901   PMID:33492380   PMID:33620261   PMID:33961781   PMID:34383782  


Genomics

Comparative Map Data
FGF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl544,300,247 - 44,389,706 (-)EnsemblGRCh38hg38GRCh38
GRCh38544,300,247 - 44,389,706 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37544,300,349 - 44,389,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36544,340,854 - 44,424,541 (-)NCBINCBI36hg18NCBI36
Build 34544,340,853 - 44,424,541NCBI
Celera544,197,375 - 44,281,044 (-)NCBI
Cytogenetic Map5p12NCBI
HuRef544,258,055 - 44,341,703 (-)NCBIHuRef
CHM1_1544,306,497 - 44,390,196 (-)NCBICHM1_1
Fgf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913118,851,235 - 118,929,109 (+)NCBIGRCm39mm39
GRCm39 Ensembl13118,806,327 - 118,928,651 (+)Ensembl
GRCm3813118,714,699 - 118,792,573 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13118,669,791 - 118,792,115 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713119,503,506 - 119,581,380 (+)NCBIGRCm37mm9NCBIm37
MGSCv3613119,833,907 - 119,910,988 (+)NCBImm8
Celera13123,161,950 - 123,245,519 (+)NCBICelera
Cytogenetic Map13D2.3NCBI
cM Map1367.14NCBI
Fgf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2250,801,897 - 50,875,428 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl250,800,992 - 50,876,866 (+)Ensembl
Rnor_6.0251,673,480 - 51,747,533 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl251,672,722 - 51,750,369 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0270,046,331 - 70,120,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4250,866,799 - 50,940,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1250,795,031 - 50,868,552 (+)NCBI
Celera246,463,913 - 46,537,376 (+)NCBICelera
Cytogenetic Map2q15NCBI
Fgf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544618,163,117 - 18,245,199 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544618,163,117 - 18,244,840 (+)NCBIChiLan1.0ChiLan1.0
FGF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1571,028,324 - 71,111,713 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl571,028,187 - 71,111,706 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0565,979,443 - 66,069,314 (+)NCBIMhudiblu_PPA_v0panPan3
FGF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1465,851,130 - 65,930,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl465,851,069 - 65,928,192 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha465,597,673 - 65,676,839 (+)NCBI
ROS_Cfam_1.0466,343,407 - 66,423,104 (+)NCBI
ROS_Cfam_1.0 Ensembl466,343,839 - 66,423,103 (+)Ensembl
UMICH_Zoey_3.1466,096,317 - 66,176,025 (+)NCBI
UNSW_CanFamBas_1.0466,218,509 - 66,297,862 (+)NCBI
UU_Cfam_GSD_1.0466,768,760 - 66,848,396 (+)NCBI
Fgf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213209,177,124 - 209,259,405 (+)NCBI
SpeTri2.0NW_00493648018,114,231 - 18,195,884 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1628,695,469 - 28,777,541 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11628,695,465 - 28,779,953 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21630,234,658 - 30,317,449 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1443,080,387 - 43,163,355 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl443,081,831 - 43,163,432 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607133,710,353 - 33,794,576 (-)NCBIVero_WHO_p1.0
Fgf10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475910,904,626 - 10,983,509 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
SHGC-82302  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37544,360,164 - 44,360,475UniSTSGRCh37
Build 36544,395,921 - 44,396,232RGDNCBI36
Celera544,252,423 - 44,252,734RGD
Cytogenetic Map5p13-p12UniSTS
HuRef544,313,076 - 44,313,387UniSTS
SHGC-110572  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37544,364,108 - 44,364,389UniSTSGRCh37
Build 36544,399,865 - 44,400,146RGDNCBI36
Celera544,256,367 - 44,256,648RGD
Cytogenetic Map5p13-p12UniSTS
HuRef544,317,020 - 44,317,301UniSTS
G16001  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37544,388,533 - 44,388,753UniSTSGRCh37
Build 36544,424,290 - 44,424,510RGDNCBI36
Celera544,280,793 - 44,281,013RGD
Cytogenetic Map5p13-p12UniSTS
HuRef544,341,452 - 44,341,672UniSTS
SHGC-100998  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37544,383,257 - 44,383,537UniSTSGRCh37
Build 36544,419,014 - 44,419,294RGDNCBI36
Celera544,275,517 - 44,275,797RGD
Cytogenetic Map5p13-p12UniSTS
HuRef544,336,176 - 44,336,456UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:775
Count of miRNA genes:551
Interacting mature miRNAs:640
Transcripts:ENST00000264664, ENST00000513107
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 215 74 164 9 10 1 267 20 79 17 251 167 9 507 111 1
Low 1902 1418 859 161 201 8 2732 1112 1066 86 852 1104 152 697 1757 1
Below cutoff 192 949 463 256 427 256 1228 997 2137 121 186 99 3 1 914 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_011446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_004465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005248264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB002097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC093289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC093537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF411527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF508782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX591263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX591285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX591408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX591430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY604046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX955123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ897310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR541665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR541688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA795795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DR003252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ351295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U67918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000264664   ⟹   ENSP00000264664
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl544,300,247 - 44,389,420 (-)Ensembl
RefSeq Acc Id: ENST00000513107   ⟹   ENSP00000426406
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl544,388,485 - 44,389,706 (-)Ensembl
RefSeq Acc Id: NM_004465   ⟹   NP_004456
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38544,300,247 - 44,389,420 (-)NCBI
GRCh37544,305,004 - 44,389,808 (-)NCBI
Build 36544,340,854 - 44,424,541 (-)NCBI Archive
HuRef544,258,055 - 44,341,703 (-)ENTREZGENE
CHM1_1544,306,497 - 44,390,196 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005248264   ⟹   XP_005248321
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38544,301,655 - 44,389,706 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_004456   ⟸   NM_004465
- Peptide Label: precursor
- UniProtKB: O15520 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005248321   ⟸   XM_005248264
- Peptide Label: isoform X1
- UniProtKB: O15520 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000426406   ⟸   ENST00000513107
RefSeq Acc Id: ENSP00000264664   ⟸   ENST00000264664

Promoters
RGD ID:6869550
Promoter ID:EPDNEW_H7940
Type:initiation region
Name:FGF10_1
Description:fibroblast growth factor 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38544,388,817 - 44,388,877EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_004465.2(FGF10):c.267dup (p.Leu90fs) duplication not provided [RCV000523783] Chr5:44388415..44388416 [GRCh38]
Chr5:44388517..44388518 [GRCh37]
Chr5:5p12		 likely pathogenic
NM_004465.2(FGF10):c.577C>T (p.Arg193Ter) single nucleotide variant Congenital absence of salivary gland [RCV000007964]|not provided [RCV000760468] Chr5:44305045 [GRCh38]
Chr5:44305147 [GRCh37]
Chr5:5p12		 pathogenic
NC_000005.10:g.(44304226_44304232)_(44357318_44357323)del deletion Congenital absence of salivary gland [RCV000007965] Chr5:44304232..44357318 [GRCh38]
Chr5:5p12		 pathogenic
NM_004465.2(FGF10):c.317G>T (p.Cys106Phe) single nucleotide variant Levy-Hollister syndrome [RCV000007966] Chr5:44388366 [GRCh38]
Chr5:44388468 [GRCh37]
Chr5:5p12		 pathogenic
NM_004465.2(FGF10):c.467T>G (p.Ile156Arg) single nucleotide variant Levy-Hollister syndrome [RCV000007967] Chr5:44305155 [GRCh38]
Chr5:44305257 [GRCh37]
Chr5:5p12		 pathogenic
NM_004465.2(FGF10):c.409A>T (p.Lys137Ter) single nucleotide variant Congenital absence of salivary gland [RCV000007968]|Levy-Hollister syndrome [RCV000007969] Chr5:44310447 [GRCh38]
Chr5:44310549 [GRCh37]
Chr5:5p12		 pathogenic
NM_004465.2(FGF10):c.240A>C (p.Arg80Ser) single nucleotide variant Congenital absence of salivary gland [RCV000007970]|Levy-Hollister syndrome [RCV000659642] Chr5:44388443 [GRCh38]
Chr5:44388545 [GRCh37]
Chr5:5p12		 pathogenic
NM_004465.2(FGF10):c.413G>A (p.Gly138Glu) single nucleotide variant Congenital absence of salivary gland [RCV000007971] Chr5:44310443 [GRCh38]
Chr5:44310545 [GRCh37]
Chr5:5p12		 pathogenic
NM_004465.2(FGF10):c.526del (p.Met176fs) deletion not provided [RCV000522239] Chr5:44305096 [GRCh38]
Chr5:44305198 [GRCh37]
Chr5:5p12		 likely pathogenic
NM_004465.1(FGF10):c.325+33027A>G single nucleotide variant Lung cancer [RCV000095973] Chr5:44355331 [GRCh38]
Chr5:44355433 [GRCh37]
Chr5:5p12		 uncertain significance
NM_004465.1(FGF10):c.325+581C>T single nucleotide variant Lung cancer [RCV000095974] Chr5:44387777 [GRCh38]
Chr5:44387879 [GRCh37]
Chr5:5p12		 uncertain significance
GRCh38/hg38 5p14.1-q11.1(chr5:26593632-50288555)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051834]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051834]|See cases [RCV000051834] Chr5:26593632..50288555 [GRCh38]
Chr5:26593741..49584389 [GRCh37]
Chr5:26629498..49620146 [NCBI36]
Chr5:5p14.1-q11.1		 pathogenic
GRCh38/hg38 5p13.2-12(chr5:35700480-45260029)x3 copy number gain See cases [RCV000051835] Chr5:35700480..45260029 [GRCh38]
Chr5:35700582..45260131 [GRCh37]
Chr5:35736339..45295888 [NCBI36]
Chr5:5p13.2-12		 pathogenic
GRCh38/hg38 5p13.2-q11.1(chr5:36374107-51103841)x3 copy number gain See cases [RCV000051836] Chr5:36374107..51103841 [GRCh38]
Chr5:36374209..50399675 [GRCh37]
Chr5:36409966..50435432 [NCBI36]
Chr5:5p13.2-q11.1		 pathogenic
GRCh38/hg38 5p15.33-12(chr5:54839-45649861)x3 copy number gain See cases [RCV000051810] Chr5:54839..45649861 [GRCh38]
Chr5:54954..45649963 [GRCh37]
Chr5:107954..45685720 [NCBI36]
Chr5:5p15.33-12		 pathogenic
NM_004465.2(FGF10):c.356del (p.Gly119fs) deletion Levy-Hollister syndrome [RCV000659644] Chr5:44310500 [GRCh38]
Chr5:44310602 [GRCh37]
Chr5:5p12		 likely pathogenic
NM_004465.2(FGF10):c.232del (p.Arg78fs) deletion Levy-Hollister syndrome [RCV000659641] Chr5:44388451 [GRCh38]
Chr5:44388553 [GRCh37]
Chr5:5p12		 likely pathogenic
NM_004465.2(FGF10):c.541A>C (p.Asn181His) single nucleotide variant Levy-Hollister syndrome [RCV000659646] Chr5:44305081 [GRCh38]
Chr5:44305183 [GRCh37]
Chr5:5p12		 uncertain significance
NM_004465.2(FGF10):c.97G>A (p.Val33Ile) single nucleotide variant Congenital absence of salivary gland [RCV001152456]|not provided [RCV000888690]|not specified [RCV000173344] Chr5:44388586 [GRCh38]
Chr5:44388688 [GRCh37]
Chr5:5p12		 benign|likely benign
GRCh38/hg38 5p15.33-11(chr5:49978-46114984)x3 copy number gain See cases [RCV000135453] Chr5:49978..46114984 [GRCh38]
Chr5:50093..46115086 [GRCh37]
Chr5:103093..46150843 [NCBI36]
Chr5:5p15.33-11		 pathogenic
GRCh38/hg38 5p13.2-q12.1(chr5:35201559-61903141)x3 copy number gain See cases [RCV000137302] Chr5:35201559..61903141 [GRCh38]
Chr5:35201661..61198968 [GRCh37]
Chr5:35237418..61234725 [NCBI36]
Chr5:5p13.2-q12.1		 pathogenic
GRCh38/hg38 5p15.33-q13.3(chr5:22149-74412725)x3 copy number gain See cases [RCV000138780] Chr5:22149..74412725 [GRCh38]
Chr5:22149..73708550 [GRCh37]
Chr5:75149..73744306 [NCBI36]
Chr5:5p15.33-q13.3		 pathogenic
GRCh37/hg19 5p15.2-12(chr5:13461664-46098927)x3 copy number gain See cases [RCV000239779] Chr5:13461664..46098927 [GRCh37]
Chr5:5p15.2-12		 pathogenic
NM_004465.2(FGF10):c.620A>C (p.His207Pro) single nucleotide variant Congenital absence of salivary gland [RCV000335259]|not provided [RCV000960252]|not specified [RCV000398550] Chr5:44305002 [GRCh38]
Chr5:44305104 [GRCh37]
Chr5:5p12		 benign|likely benign
NM_004465.2(FGF10):c.426C>T (p.Gly142=) single nucleotide variant Congenital absence of salivary gland [RCV000277744] Chr5:44310430 [GRCh38]
Chr5:44310532 [GRCh37]
Chr5:5p12		 likely benign|uncertain significance
NM_004465.2(FGF10):c.591C>T (p.Thr197=) single nucleotide variant Congenital absence of salivary gland [RCV000299866]|not provided [RCV000970124] Chr5:44305031 [GRCh38]
Chr5:44305133 [GRCh37]
Chr5:5p12		 benign
NM_004465.2(FGF10):c.261G>A (p.Lys87=) single nucleotide variant Congenital absence of salivary gland [RCV000364753] Chr5:44388422 [GRCh38]
Chr5:44388524 [GRCh37]
Chr5:5p12		 benign|likely benign
NM_004465.2(FGF10):c.430-15G>C single nucleotide variant Congenital absence of salivary gland [RCV000312899] Chr5:44305207 [GRCh38]
Chr5:44305309 [GRCh37]
Chr5:5p12		 benign
NM_004465.2(FGF10):c.186C>A (p.Ser62Arg) single nucleotide variant Congenital absence of salivary gland [RCV000320633] Chr5:44388497 [GRCh38]
Chr5:44388599 [GRCh37]
Chr5:5p12		 uncertain significance
NM_004465.1(FGF10):c.*5A>T single nucleotide variant Congenital absence of salivary gland [RCV000315768]|Levy-Hollister syndrome [RCV000361118]|not provided [RCV001692088] Chr5:44304990 [GRCh38]
Chr5:44305092 [GRCh37]
Chr5:5p12		 benign|likely benign
NM_004465.2(FGF10):c.144G>A (p.Glu48=) single nucleotide variant Congenital absence of salivary gland [RCV000377629] Chr5:44388539 [GRCh38]
Chr5:44388641 [GRCh37]
Chr5:5p12		 uncertain significance
NM_004465.2(FGF10):c.624A>G (p.Ser208=) single nucleotide variant Congenital absence of salivary gland [RCV000287224]|Levy-Hollister syndrome [RCV000398807] Chr5:44304998 [GRCh38]
Chr5:44305100 [GRCh37]
Chr5:5p12		 uncertain significance
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p14.2-11(chr5:24281195-46389339)x3 copy number gain See cases [RCV000512120] Chr5:24281195..46389339 [GRCh37]
Chr5:5p14.2-11		 likely pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
NM_004465.2(FGF10):c.1A>G (p.Met1Val) single nucleotide variant Levy-Hollister syndrome [RCV000659640] Chr5:44388682 [GRCh38]
Chr5:44388784 [GRCh37]
Chr5:5p12		 likely pathogenic
NM_004465.2(FGF10):c.256del (p.Thr86fs) deletion Levy-Hollister syndrome [RCV000659643] Chr5:44388427 [GRCh38]
Chr5:44388529 [GRCh37]
Chr5:5p12		 likely pathogenic
NM_004465.2(FGF10):c.401T>A (p.Met134Lys) single nucleotide variant Levy-Hollister syndrome [RCV000659645] Chr5:44310455 [GRCh38]
Chr5:44310557 [GRCh37]
Chr5:5p12		 likely pathogenic
NM_004465.2(FGF10):c.550G>A (p.Gly184Arg) single nucleotide variant Levy-Hollister syndrome [RCV000659647] Chr5:44305072 [GRCh38]
Chr5:44305174 [GRCh37]
Chr5:5p12		 likely pathogenic
GRCh37/hg19 5p14.1-12(chr5:27227243-45685844)x3 copy number gain not provided [RCV000682542] Chr5:27227243..45685844 [GRCh37]
Chr5:5p14.1-12		 pathogenic
NM_004465.2(FGF10):c.429+210del deletion not provided [RCV001566814] Chr5:44310217 [GRCh38]
Chr5:44310319 [GRCh37]
Chr5:5p12		 likely benign
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
NM_004465.2(FGF10):c.430-80G>A single nucleotide variant not provided [RCV001541753] Chr5:44305272 [GRCh38]
Chr5:44305374 [GRCh37]
Chr5:5p12		 likely benign
NM_004465.2(FGF10):c.430-221A>T single nucleotide variant not provided [RCV001681473] Chr5:44305413 [GRCh38]
Chr5:44305515 [GRCh37]
Chr5:5p12		 benign
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32		 uncertain significance
GRCh37/hg19 5p13.2-11(chr5:34453883-46389339)x3 copy number gain not provided [RCV000848003] Chr5:34453883..46389339 [GRCh37]
Chr5:5p13.2-11		 pathogenic
NM_004465.2(FGF10):c.430-93_430-92del deletion not provided [RCV001552123] Chr5:44305284..44305285 [GRCh38]
Chr5:44305386..44305387 [GRCh37]
Chr5:5p12		 likely benign
NM_004465.2(FGF10):c.429+37T>A single nucleotide variant not provided [RCV001685911] Chr5:44310390 [GRCh38]
Chr5:44310492 [GRCh37]
Chr5:5p12		 benign
NM_004465.2(FGF10):c.-294del deletion not provided [RCV001619751] Chr5:44388976 [GRCh38]
Chr5:44389078 [GRCh37]
Chr5:5p12		 benign
NM_004465.2(FGF10):c.610A>G (p.Met204Val) single nucleotide variant Congenital absence of salivary gland [RCV001157920] Chr5:44305012 [GRCh38]
Chr5:44305114 [GRCh37]
Chr5:5p12		 benign
NM_004465.2(FGF10):c.102T>G (p.Pro34=) single nucleotide variant not provided [RCV000934660] Chr5:44388581 [GRCh38]
Chr5:44388683 [GRCh37]
Chr5:5p12		 likely benign
GRCh37/hg19 5p13.2-11(chr5:34984696-46405042)x3 copy number gain not provided [RCV001537930] Chr5:34984696..46405042 [GRCh37]
Chr5:5p13.2-11		 pathogenic
NM_004465.2(FGF10):c.429+280C>T single nucleotide variant not provided [RCV001540336] Chr5:44310147 [GRCh38]
Chr5:44310249 [GRCh37]
Chr5:5p12		 likely benign
NM_004465.2(FGF10):c.-33G>A single nucleotide variant not provided [RCV001652260] Chr5:44388715 [GRCh38]
Chr5:44388817 [GRCh37]
Chr5:5p12		 benign
NM_004465.2(FGF10):c.116C>A (p.Ala39Asp) single nucleotide variant Levy-Hollister syndrome [RCV001196292] Chr5:44388567 [GRCh38]
Chr5:44388669 [GRCh37]
Chr5:5p12		 uncertain significance
NM_004465.2(FGF10):c.423T>C (p.Tyr141=) single nucleotide variant Congenital absence of salivary gland [RCV001157921] Chr5:44310433 [GRCh38]
Chr5:44310535 [GRCh37]
Chr5:5p12		 uncertain significance
GRCh37/hg19 5p13.1-q11.1(chr5:38432180-49441945)x3 copy number gain not provided [RCV001005674] Chr5:38432180..49441945 [GRCh37]
Chr5:5p13.1-q11.1		 pathogenic
GRCh37/hg19 5p13.3-12(chr5:29081195-45294031)x3 copy number gain See cases [RCV001310288] Chr5:29081195..45294031 [GRCh37]
Chr5:5p13.3-12		 pathogenic
NC_000005.9:g.(?_44305097)_(45696195_?)dup duplication Early infantile epileptic encephalopathy with suppression bursts [RCV001346561] Chr5:44305097..45696195 [GRCh37]
Chr5:5p12		 uncertain significance
NC_000005.9:g.44300489_44312646del deletion Levy-Hollister syndrome [RCV001726492] Chr5:44300489..44312646 [GRCh37]
Chr5:5p12		 pathogenic
NM_004465.2(FGF10):c.190G>T (p.Gly64Ter) single nucleotide variant not provided [RCV001783273]   pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3666 AgrOrtholog
COSMIC FGF10 COSMIC
Ensembl Genes ENSG00000070193 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000264664 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000426406 UniProtKB/TrEMBL
Ensembl Transcript ENST00000264664 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000513107 UniProtKB/TrEMBL
GTEx ENSG00000070193 GTEx
HGNC ID HGNC:3666 ENTREZGENE
Human Proteome Map FGF10 Human Proteome Map
InterPro FGF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibroblast_GF_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:2255 UniProtKB/Swiss-Prot
NCBI Gene 2255 ENTREZGENE
OMIM 149730 OMIM
  180920 OMIM
  602115 OMIM
PANTHER PTHR11486 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11486:SF21 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA28106 PharmGKB
PRINTS HBGFFGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A7U3JW18_HUMAN UniProtKB/TrEMBL
  D6RG33_HUMAN UniProtKB/TrEMBL
  FGF10_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q8NFI9_HUMAN UniProtKB/TrEMBL
UniProt Secondary C7FDY0 UniProtKB/Swiss-Prot
  Q6FHR3 UniProtKB/Swiss-Prot
  Q6FHT6 UniProtKB/Swiss-Prot
  Q96P59 UniProtKB/Swiss-Prot