ONTOLOGY REPORT - ANNOTATIONS |
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Term: | negative regulation of macroautophagy |
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Accession: | GO:0016242
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browse the term
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Definition: | Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy. |
Synonyms: | exact_synonym: | down regulation of macroautophagy; downregulation of macroautophagy; negative regulation of starvation-induced autophagy |
| narrow_synonym: | inhibition of macroautophagy |
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Hmox1 |
heme oxygenase 1 |
acts_upstream_of_or_within |
IMP |
(PMID:20705711) |
MGI |
PMID:20705711 |
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NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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Lrrk2 |
leucine-rich repeat kinase 2 |
involved_in |
ISO |
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GO_Central |
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GO_REF:0000119 |
NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323
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Lzts1 |
leucine zipper, putative tumor suppressor 1 |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr 8:69,585,311...69,636,901
Ensembl chr 8:69,585,321...69,636,877
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Mtor |
mechanistic target of rapamycin kinase |
acts_upstream_of_or_within involved_in |
IMP IBA ISO |
(PMID:16714284), (PMID:23274896) (PMID:25327288) |
MGI GO_Central |
PMID:16714284 PMID:23274896 PMID:25327288 |
GO_REF:0000033 |
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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Npc1 |
NPC intracellular cholesterol transporter 1 |
acts_upstream_of_or_within |
IGI IMP |
(PMID:17468177) |
MGI |
PMID:17468177 |
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NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457
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Nrbp2 |
nuclear receptor binding protein 2 |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr15:75,957,364...75,963,539
Ensembl chr15:75,957,367...75,963,476
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Pink1 |
PTEN induced putative kinase 1 |
involved_in |
ISO |
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GO_Central |
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GO_REF:0000119 |
NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
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Poldip2 |
polymerase (DNA-directed), delta interacting protein 2 |
acts_upstream_of_or_within |
IMP |
(PMID:24797518) |
MGI |
PMID:24797518 |
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NCBI chr11:78,403,105...78,413,562
Ensembl chr11:78,403,019...78,413,562
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Qsox1 |
quiescin Q6 sulfhydryl oxidase 1 |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr 1:155,653,901...155,688,645
Ensembl chr 1:155,651,775...155,688,635
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Smcr8 |
Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) |
involved_in |
ISO ISS |
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GO_Central UniProt |
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GO_REF:0000024 GO_REF:0000119 |
NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113
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Tsc1 |
TSC complex subunit 1 |
involved_in |
ISS ISO |
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ParkinsonsUK-UCL GO_Central |
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GO_REF:0000024 GO_REF:0000096 |
NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179
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Tsc2 |
TSC complex subunit 2 |
involved_in |
ISO |
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RGD GO_Central |
PMID:24599401 |
GO_REF:0000096 RGD:11568679 |
NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
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Usp36 |
ubiquitin specific peptidase 36 |
involved_in |
ISS ISO |
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UniProt GO_Central |
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GO_REF:0000024 GO_REF:0000119 |
NCBI chr11:118,150,477...118,181,086
Ensembl chr11:118,150,477...118,181,070
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Hdac6 |
histone deacetylase 6 |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr X:7,796,355...7,814,284
Ensembl chr X:7,796,359...7,814,128
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Lypla1 |
lysophospholipase 1 |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr 1:4,878,046...4,916,958
Ensembl chr 1:4,878,011...4,918,633
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Becn1 |
beclin 1, autophagy related |
acts_upstream_of_or_within |
IMP |
(PMID:27994061) |
MGI |
PMID:27994061 |
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NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
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Ehmt2 |
euchromatic histone lysine N-methyltransferase 2 |
acts_upstream_of_or_within |
IMP |
(PMID:23918802) |
MGI |
PMID:23918802 |
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NCBI chr17:35,117,427...35,133,049
Ensembl chr17:35,117,445...35,133,028
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Fez1 |
fasciculation and elongation protein zeta 1 |
involved_in |
ISS |
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GO_Central |
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GO_REF:0000024 |
NCBI chr 9:36,732,694...36,790,220
Ensembl chr 9:36,733,160...36,790,220
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Fez2 |
fasciculation and elongation protein zeta 2 |
involved_in |
ISS |
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GO_Central |
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GO_REF:0000024 |
NCBI chr17:78,676,641...78,725,581
Ensembl chr17:78,676,641...78,725,581
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Lrrk2 |
leucine-rich repeat kinase 2 |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323
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Mtm1 |
X-linked myotubular myopathy gene 1 |
involved_in acts_upstream_of_or_within |
IBA IMP |
(PMID:23695157) |
GO_Central MGI |
PMID:23695157 |
GO_REF:0000033 |
NCBI chr X:70,254,373...70,359,019
Ensembl chr X:70,254,373...70,359,297
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Nupr1 |
nuclear protein transcription regulator 1 |
involved_in |
ISO ISS |
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GO_Central UniProt |
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GO_REF:0000024 GO_REF:0000119 |
NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
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Phf23 |
PHD finger protein 23 |
involved_in |
IBA ISS |
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GO_Central |
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GO_REF:0000024 GO_REF:0000033 |
NCBI chr11:69,886,592...69,890,837
Ensembl chr11:69,886,603...69,890,835
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Pink1 |
PTEN induced putative kinase 1 |
involved_in |
IEA ISO |
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Ensembl GO_Central |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
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Scfd1 |
Sec1 family domain containing 1 |
involved_in |
IEA ISO |
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Ensembl GO_Central |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr12:51,424,296...51,496,887
Ensembl chr12:51,424,293...51,496,884
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Sec22b |
SEC22 homolog B, vesicle trafficking protein |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr 3:97,808,543...97,829,634
Ensembl chr 3:97,808,506...97,830,592
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Smcr8 |
Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) |
involved_in |
ISS ISO |
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UniProt GO_Central |
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GO_REF:0000024 GO_REF:0000119 |
NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113
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Tmem39a |
transmembrane protein 39a |
involved_in |
IBA ISS ISO |
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GO_Central UniProt |
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GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 |
NCBI chr16:38,379,060...38,412,524
Ensembl chr16:38,379,060...38,412,524
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Clec16a |
C-type lectin domain family 16, member A |
involved_in |
ISO |
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GO_Central |
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GO_REF:0000119 |
NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742
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Phf23 |
PHD finger protein 23 |
involved_in |
IBA ISS |
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GO_Central |
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GO_REF:0000024 GO_REF:0000033 |
NCBI chr11:69,886,592...69,890,837
Ensembl chr11:69,886,603...69,890,835
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Rubcn |
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein |
involved_in |
IBA IEA ISO |
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GO_Central Ensembl |
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GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 |
NCBI chr16:32,642,072...32,698,121
Ensembl chr16:32,642,073...32,698,136
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Tmem39a |
transmembrane protein 39a |
involved_in |
IBA ISO ISS |
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GO_Central UniProt |
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GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 |
NCBI chr16:38,379,060...38,412,524
Ensembl chr16:38,379,060...38,412,524
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Ubqln4 |
ubiquilin 4 |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr 3:88,460,984...88,477,032
Ensembl chr 3:88,461,065...88,477,032
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Clec16a |
C-type lectin domain family 16, member A |
acts_upstream_of_or_within |
IMP |
(PMID:24949970) |
MGI |
PMID:24949970 |
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NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742
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Pink1 |
PTEN induced putative kinase 1 |
involved_in |
ISO IEA |
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GO_Central Ensembl |
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GO_REF:0000107 GO_REF:0000119 |
NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
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Rnf41 |
ring finger protein 41 |
acts_upstream_of_or_within |
IGI |
(PMID:24949970) |
MGI |
PMID:24949970 |
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NCBI chr10:128,247,485...128,277,310
Ensembl chr10:128,247,526...128,277,310
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Tigar |
Trp53 induced glycolysis regulatory phosphatase |
acts_upstream_of_or_within |
IMP |
(PMID:22044588) |
MGI |
PMID:22044588 |
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NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520
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Trp53 |
transformation related protein 53 |
acts_upstream_of_or_within |
IMP |
(PMID:22044588) |
MGI |
PMID:22044588 |
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NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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Tspo |
translocator protein |
involved_in |
IMP |
(PMID:25470454) |
ParkinsonsUK-UCL |
PMID:25470454 |
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NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404
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Usp30 |
ubiquitin specific peptidase 30 |
involved_in |
ISO IEA |
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RGD Ensembl GO_Central |
PMID:24896179 |
GO_REF:0000096 GO_REF:0000107 RGD:13208875 |
NCBI chr 5:114,238,395...114,261,571
Ensembl chr 5:114,203,522...114,262,781
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Htra2 |
HtrA serine peptidase 2 |
involved_in |
IMP |
(PMID:24709290) |
ParkinsonsUK-UCL |
PMID:24709290 |
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NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254
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Vps13c |
vacuolar protein sorting 13C |
involved_in |
ISO ISS |
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GO_Central ParkinsonsUK-UCL |
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GO_REF:0000024 GO_REF:0000119 |
NCBI chr 9:67,747,594...67,905,026
Ensembl chr 9:67,747,678...67,902,920
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Term paths to the root
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