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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of autophagy
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Accession:GO:0010507 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.



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negative regulation of autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:27994061)
Ensembl
RGD
PMID:27994061 GO_REF:0000107 NCBI chr15:45,005,648...45,111,416 JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA
(PMID:18387192)
GO_REF:0000107
RGD
Ensembl
PMID:18387192 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
ISS
IEA
(PMID:21358617)
GO_REF:0000024
GO_REF:0000107
(PMID:36812915)
RGD
UniProt
Ensembl
PMID:21358617 PMID:36812915 GO_REF:0000024 GO_REF:0000107 NCBI chr13:23,204,464...23,366,900 JBrowse link
G Becn1 beclin 1 acts_upstream_of_or_within ISO (PMID:27994061) RGD PMID:27994061 NCBI chr10:86,731,649...86,747,002 JBrowse link
G Bmf Bcl2 modifying factor involved_in ISO
IBA
IEA
(PMID:23629966)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:23629966 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:125,953,466...125,974,087 JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISS
ISO
GO_REF:0000024
(PMID:29164996)
UniProt
RGD
PMID:29164996 GO_REF:0000024 NCBI chr 5:171,757,181...171,761,271 JBrowse link
G Dap death-associated protein involved_in ISO
IBA
(PMID:20537536)
GO_REF:0000033
RGD
GO_Central
PMID:20537536 GO_REF:0000033 NCBI chr 2:82,199,206...82,251,771 JBrowse link
G Dapl1 death associated protein-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:43,960,993...43,980,940 JBrowse link
G Eif4e eukaryotic translation initiation factor 4E NOT|involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr 2:229,736,309...229,772,628 JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr11:93,726,322...93,746,387 JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr 1:165,181,433...165,193,583 JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 NOT|involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr 5:155,481,378...155,702,194 JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:32561715) RGD PMID:32561715 NCBI chr 7:114,987,857...115,058,652 JBrowse link
G Erfe erythroferrone involved_in ISS
ISO
GO_REF:0000024
(PMID:24187137)
UniProt
RGD
PMID:24187137 GO_REF:0000024 NCBI chr 9:99,404,512...99,412,383 JBrowse link
G Foxk1 forkhead box K1 involved_in ISO (PMID:25402684) RGD PMID:25402684 NCBI chr12:12,110,119...12,175,089 JBrowse link
G Foxk2 forkhead box K2 involved_in ISO (PMID:25402684) RGD PMID:25402684 NCBI chr10:107,040,933...107,090,860 JBrowse link
G Gata4 GATA binding protein 4 IMP RGD PMID:19901028 RGD:5131537 NCBI chr15:41,635,572...41,707,252 JBrowse link
G Golga2 golgin A2 involved_in ISO (PMID:22735382) RGD PMID:22735382 NCBI chr 3:15,583,862...15,604,279 JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 acts_upstream_of_or_within ISO MGI:3613033 (PMID:20041218) RGD PMID:20041218 NCBI chr 8:75,796,347...75,965,347 JBrowse link
G Il10 interleukin 10 involved_in ISO (PMID:26962683) RGD PMID:26962683 NCBI chr13:45,024,921...45,029,586 JBrowse link
G Il10ra interleukin 10 receptor subunit alpha involved_in ISO (PMID:26962683) RGD PMID:26962683 NCBI chr 8:54,459,754...54,474,786 JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:15680329) RGD PMID:15680329 NCBI chr10:38,906,460...38,908,810 JBrowse link
G Kdm4a lysine demethylase 4A involved_in ISO (PMID:25660547) RGD PMID:25660547 NCBI chr 5:131,672,754...131,719,534 JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISS
ISO
GO_REF:0000024
(PMID:29769719)
UniProt
RGD
PMID:29769719 GO_REF:0000024 NCBI chr11:83,190,891...83,231,746 JBrowse link
G Lep leptin involved_in ISO
ISS
(PMID:25060689)
GO_REF:0000024
RGD
UniProt
PMID:25060689 GO_REF:0000024 NCBI chr 4:58,626,529...58,640,663 JBrowse link
G Lepr leptin receptor involved_in ISO
IEA
ISS
(PMID:25060689)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:25060689 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:121,409,735...121,593,201 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:24113155) RGD PMID:24113155 NCBI chr 2:185,884,840...185,912,532 JBrowse link
G Mir223 microRNA 223 IDA RGD PMID:29608885 RGD:21408565 NCBI chr  X:61,141,887...61,141,996 JBrowse link
G Mtmr9 myotubularin related protein 9 involved_in ISO UniProtKB:Q96EF0-1 (PMID:22647598) RGD PMID:22647598 NCBI chr15:37,769,161...37,791,195 JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IMP
ISO
IEA
ISS
(PMID:21258367)
GO_REF:0000117
(PMID:22424946), (PMID:22576015), (PMID:30704899), (PMID:32561715)
GO_REF:0000024
RGD
UniProt
PMID:21258367 PMID:22424946 PMID:22576015 PMID:30704899 PMID:32561715 More... GO_REF:0000024 GO_REF:0000117, RGD:10040964 NCBI chr 5:164,167,985...164,277,438 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IMP RGD PMID:26601421 RGD:13781888 NCBI chr 6:55,152,756...55,189,547 JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISS
ISO
IMP
GO_REF:0000024
(PMID:20181828)
UniProt
RGD
PMID:20181828 PMID:20181828 GO_REF:0000024, RGD:14390062 NCBI chr 1:190,643,866...190,645,901 JBrowse link
G Ptk2 protein tyrosine kinase 2 acts_upstream_of_or_within ISO (PMID:27994061) RGD PMID:27994061 NCBI chr 7:107,015,730...107,220,865 JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23991106) RGD PMID:23991106 NCBI chr 2:191,366,761...191,414,782 JBrowse link
G Rasip1 Ras interacting protein 1 involved_in ISO (PMID:22354037) RGD PMID:22354037 NCBI chr 1:105,233,599...105,246,028 JBrowse link
G Rnf5 ring finger protein 5 acts_upstream_of_or_within ISO MGI:3775796 (PMID:23093945) RGD PMID:23093945 NCBI chr20:4,145,539...4,147,985 JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO (PMID:32561715) RGD PMID:32561715 NCBI chr10:105,376,943...105,675,416 JBrowse link
G Rraga Ras-related GTP binding A involved_in ISO
IBA
IEA
ISS
(PMID:25936802)
(PMID:23263183)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
UniProt
PMID:23263183 PMID:25936802 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:106,159,335...106,160,930 JBrowse link
G RragB Ras-related GTP binding B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:21,560,313...21,610,550 JBrowse link
G Rragc Ras-related GTP binding C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:141,433,014...141,452,546 JBrowse link
G Rragd Ras-related GTP binding D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:52,170,234...52,205,700 JBrowse link
G Rubcn rubicon autophagy regulator involved_in ISO (PMID:19270696) RGD PMID:19270696 NCBI chr11:67,907,534...67,964,347 JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:20543840)
UniProt
Ensembl
RGD
PMID:20543840 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:93,181,472...93,204,499 JBrowse link
G Slc7a5 solute carrier family 7 member 5 IMP RGD PMID:25049270 RGD:151361107 NCBI chr19:66,843,808...66,872,412 JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA
(PMID:26962683)
GO_REF:0000107
RGD
Ensembl
PMID:26962683 GO_REF:0000107 NCBI chr10:86,311,528...86,363,513 JBrowse link
G Stk38l serine/threonine kinase 38 like involved_in ISO (PMID:35670107) RGD PMID:35670107 NCBI chr 4:181,346,969...181,423,844 JBrowse link
G Tbc1d14 TBC1 domain family, member 14 involved_in IEA
ISO
GO_REF:0000107
(PMID:22613832)
Ensembl
RGD
PMID:22613832 GO_REF:0000107 NCBI chr14:74,172,652...74,272,182 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:28802038) RGD PMID:28802038 NCBI chr 9:12,647,605...12,654,190 JBrowse link
G Trim27 tripartite motif-containing 27 involved_in ISO (PMID:35670107) RGD PMID:35670107 NCBI chr17:43,538,282...43,550,633 JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:30902965) RGD PMID:30902965 NCBI chr 4:146,772,483...146,779,376 JBrowse link
G Washc1 WASH complex subunit 1 involved_in ISO (PMID:23974797) RGD PMID:23974797 NCBI chr 9:105,722,779...105,830,836 JBrowse link
G Wdr6 WD repeat domain 6 involved_in ISO
IEA
(PMID:22354037)
GO_REF:0000107
RGD
Ensembl
PMID:22354037 GO_REF:0000107 NCBI chr 8:109,268,079...109,274,504 JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:27911840)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:27911840 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:154,800,590...154,926,147 JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 involved_in ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:43,217,168...43,232,828 JBrowse link
negative regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in ISO (PMID:31857589) RGD PMID:31857589 NCBI chr  X:14,550,645...14,572,445 JBrowse link
G Lypla1 lysophospholipase 1 involved_in ISO (PMID:37802024) RGD PMID:37802024 NCBI chr 5:14,679,605...14,708,774 JBrowse link
negative regulation of autophagosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 acts_upstream_of_or_within ISO MGI:2683833 (PMID:27994061) RGD PMID:27994061 NCBI chr10:86,731,649...86,747,002 JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 acts_upstream_of_or_within ISO (PMID:23918802) RGD PMID:23918802 NCBI chr20:3,924,263...3,941,238 JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 involved_in ISO
ISS
(PMID:25495476)
GO_REF:0000024
RGD
GO_Central
PMID:25495476 GO_REF:0000024 NCBI chr 8:36,544,462...36,589,684 JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25495476)
GO_Central
Ensembl
RGD
PMID:25495476 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:16,654,572...16,694,628 JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:23916833) RGD PMID:23916833 NCBI chr 7:124,706,246...124,867,234 JBrowse link
G Mtm1 myotubularin 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2450997 (PMID:23695157)
GO_Central
RGD
PMID:23695157 GO_REF:0000033 NCBI chr 6:488,923...506,882 JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISS
ISO
GO_REF:0000024
(PMID:20181828)
UniProt
RGD
PMID:20181828 GO_REF:0000024 NCBI chr 1:190,643,866...190,645,901 JBrowse link
G Phf23 PHD finger protein 23 involved_in ISO
IBA
IEA
ISS
(PMID:25484098)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
PMID:25484098 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:54,718,663...54,722,784 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:155,813,838...155,825,950 JBrowse link
G Scfd1 sec1 family domain containing 1 involved_in ISO (PMID:21242315) RGD PMID:21242315 NCBI chr 6:68,795,810...68,874,076 JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein involved_in ISO (PMID:21242315) RGD PMID:21242315 NCBI chr 2:185,500,029...185,520,811 JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit involved_in ISO (PMID:28195531) RGD PMID:28195531 NCBI chr10:45,957,146...45,968,388 JBrowse link
G Tmem39a transmembrane protein 39a involved_in ISO
IBA
ISS
(PMID:31806350)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:31806350 GO_REF:0000024 GO_REF:0000033 NCBI chr11:62,160,631...62,189,964 JBrowse link
negative regulation of autophagosome maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A involved_in ISO (PMID:28223137) RGD PMID:28223137 NCBI chr10:5,434,725...5,631,246 JBrowse link
G Phf23 PHD finger protein 23 involved_in ISO
IBA
IEA
ISS
(PMID:25484098)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
PMID:25484098 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:54,718,663...54,722,784 JBrowse link
G Rubcn rubicon autophagy regulator involved_in ISO
IBA
(PMID:21062745)
GO_REF:0000033
RGD
GO_Central
PMID:21062745 GO_REF:0000033 NCBI chr11:67,907,534...67,964,347 JBrowse link
G Tmem39a transmembrane protein 39a involved_in ISO
IBA
ISS
(PMID:31806350)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:31806350 GO_REF:0000024 GO_REF:0000033 NCBI chr11:62,160,631...62,189,964 JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO (PMID:23459205) RGD PMID:23459205 NCBI chr 2:174,012,726...174,028,062 JBrowse link
negative regulation of chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsa cathepsin A involved_in ISO UniProtKB:P10619 (PMID:12505983) RGD PMID:12505983 NCBI chr 3:153,569,106...153,574,983 JBrowse link
G Snca synuclein alpha involved_in ISO
IEA
(PMID:20697033)
GO_REF:0000107
RGD
Ensembl
PMID:20697033 GO_REF:0000107 NCBI chr 4:91,026,474...91,127,444 JBrowse link
negative regulation of macroautophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2429784 (PMID:20705711)
Ensembl
RGD
PMID:20705711 GO_REF:0000107 NCBI chr19:13,452,365...13,479,823 JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:19640926) RGD PMID:19640926 NCBI chr 7:124,706,246...124,867,234 JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 involved_in ISO (PMID:22354037) RGD PMID:22354037 NCBI chr16:20,542,756...20,598,204 JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(PMID:25327288)
(PMID:16714284), (PMID:23274896)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:16714284 PMID:23274896 PMID:25327288 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:164,167,985...164,277,438 JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 acts_upstream_of_or_within ISO MGI:1857409|MGI:1891828 (PMID:17468177) RGD PMID:17468177 NCBI chr18:3,379,482...3,425,100 JBrowse link
G Nrbp2 nuclear receptor binding protein 2 involved_in ISO (PMID:22354037) RGD PMID:22354037 NCBI chr 7:109,679,330...109,685,656 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:155,813,838...155,825,950 JBrowse link
G Poldip2 DNA polymerase delta interacting protein 2 acts_upstream_of_or_within ISO MGI:4044390 (PMID:24797518) RGD PMID:24797518 NCBI chr10:63,407,237...63,417,605 JBrowse link
G Qsox1 quiescin sulfhydryl oxidase 1 involved_in ISO (PMID:24475161) RGD PMID:24475161 NCBI chr13:67,949,780...67,987,434 JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit involved_in ISO (PMID:28195531) RGD PMID:28195531 NCBI chr10:45,957,146...45,968,388 JBrowse link
G Tsc1 TSC complex subunit 1 involved_in IMP PMID:23435171 ParkinsonsUK-UCL PMID:23435171 RGD:10448950 NCBI chr 3:32,367,434...32,416,565 JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:24599401 RGD:11568679 NCBI chr10:14,125,679...14,160,317 JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:22622177) RGD PMID:22622177 NCBI chr10:103,497,349...103,528,877 JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (PMID:24949970) RGD PMID:24949970 NCBI chr10:5,434,725...5,631,246 JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:38992176)
Ensembl
RGD
PMID:38992176 GO_REF:0000107 NCBI chr 5:40,752,513...40,826,154 JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:155,813,838...155,825,950 JBrowse link
G Pptc7 protein phosphatase targeting COQ7 involved_in IEA
ISO
GO_REF:0000107
(PMID:38992176)
Ensembl
RGD
PMID:38992176 GO_REF:0000107 NCBI chr12:34,249,963...34,288,339 JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within ISO MGI:1921624 (PMID:24949970) RGD PMID:24949970 NCBI chr 7:838,160...876,869 JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO MGI:5319187 (PMID:22044588) RGD PMID:22044588 NCBI chr 4:161,613,306...161,632,248 JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857263 (PMID:22044588)
Ensembl
RGD
PMID:22044588 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300 JBrowse link
G Tspo translocator protein involved_in ISO (PMID:25470454) RGD PMID:25470454 NCBI chr 7:116,600,214...116,610,461 JBrowse link
G Usp30 ubiquitin specific peptidase 30 IMP RGD PMID:24896179 RGD:13208875 NCBI chr12:42,501,345...42,555,311 JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:24709290) RGD PMID:24709290 NCBI chr 4:117,114,631...117,117,793 JBrowse link
G Vps13c vacuolar protein sorting 13 homolog C involved_in ISO
ISS
(PMID:26942284)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:26942284 GO_REF:0000024 NCBI chr 8:68,478,366...68,651,893 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      process utilizing autophagic mechanism 555
        autophagy 555
          negative regulation of autophagy 89
            negative regulation of autophagy of mitochondrion + 11
            negative regulation of chaperone-mediated autophagy 2
            negative regulation of macroautophagy + 37
Path 2
Term Annotations click to browse term
  biological_process 20534
    biological regulation 13821
      regulation of biological process 13375
        regulation of cellular process 13013
          regulation of metabolic process 6834
            negative regulation of metabolic process 3156
              negative regulation of catabolic process 377
                negative regulation of autophagy 89
                  negative regulation of autophagy of mitochondrion + 11
                  negative regulation of chaperone-mediated autophagy 2
                  negative regulation of macroautophagy + 37
paths to the root