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ONTOLOGY REPORT - ANNOTATIONS


Term:flubendazole
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Accession:CHEBI:77095 term browser browse the term
Definition:A member of the class of mebendazole in which the benzoyl group is replaced by a p-fluorobenzoyl group. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.
Synonyms:exact_synonym: methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
 related_synonym: (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester;   Formula=C16H12FN3O3;   InChI=1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22);   InChIKey=CPEUVMUXAHMANV-UHFFFAOYSA-N;   Methyl N-(5-(p-fluorobenzoyl)-2-benzimidazolyl)carbamate;   R 17,889;   R 17899;   SMILES=COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1ccc(F)cc1;   flubendazol;   flubendazolum;   methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate
 xref: CAS:31430-15-6;   Drug_Central:1186;   KEGG:D04200;   LINCS:LSM-5916
 xref_mesh: MESH:C018945
 xref: PMID:20348394;   PMID:20444026;   PMID:21609260;   PMID:22640491;   PMID:22717022;   PMID:23075539;   PMID:23287076;   PMID:23884106;   PMID:24297155;   PMID:3810656;   PMID:538808;   PMID:6126101;   PMID:7101714;   PMID:7212160;   Patent:DE2029637;   Patent:US3657267;   Reaxys:763480;   Wikipedia:Flubendazole


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flubendazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:6480464
G Cdh2 cadherin 2 JBrowse link 18 8,146,971 8,366,037 RGD:6480464
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:6480464
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:6480464
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        aetiopathogenetic role 18840
          teratogenic agent 15867
            flubendazole 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18475
                              organic divalent group 18468
                                organodiyl group 18468
                                  carbonyl group 18366
                                    carbonyl compound 18366
                                      carboxylic ester 14074
                                        carbamate ester 7341
                                          flubendazole 7
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