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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Betanin
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Accession:CHEBI:3080 term browser browse the term
Definition:A betalain that has formula C24H26N2O13.
Synonyms:related_synonym: Formula=C24H26N2O13;   InChI=1S/C24H26N2O13/c27-8-17-18(29)19(30)20(31)24(39-17)38-16-6-10-5-14(23(36)37)26(13(10)7-15(16)28)2-1-9-3-11(21(32)33)25-12(4-9)22(34)35/h1-3,6-7,12,14,17-20,24,27,29-31H,4-5,8H2,(H4,28,32,33,34,35,36,37)/t12-,14-,17+,18+,19-,20+,24+/m0/s1;   InChIKey=DHHFDKNIEVKVKS-FMOSSLLZSA-N;   SMILES=OC[C@H]1O[C@@H](Oc2cc3C[C@@H](C([O-])=O)\\[N+](=C/C=C4C[C@H](NC(=C\\4)C(O)=O)C(O)=O)c3cc2O)[C@H](O)[C@@H](O)[C@@H]1O
 xref: CAS:7659-95-2;   KEGG:C08540;   KNApSAcK:C00001584
 xref_mesh: MESH:C020228


show annotations for term's descendants           Sort by:
Betanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP betanin inhibits the reaction [Cytarabine results in increased activity of ACHE protein] CTD PMID:36419121 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO betanin results in decreased expression of AKT1 protein CTD PMID:37401526 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in increased expression of BAX protein]]; betanin inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:33661552 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP betanin inhibits the reaction [Cytarabine results in increased activity of BCHE protein] CTD PMID:36419121 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]]; betanin inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein] CTD PMID:33661552 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Cat catalase multiple interactions EXP betanin inhibits the reaction [Paraquat results in decreased activity of CAT protein] CTD PMID:24799198 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions EXP betanin inhibits the reaction [Fructose results in increased expression of CCN2 protein] CTD PMID:25559852 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP betanin inhibits the reaction [Paraquat results in increased expression of CYP3A2 mRNA] CTD PMID:24799198 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of GCLM mRNA]]; betanin inhibits the reaction [Cisplatin results in decreased expression of GCLM mRNA] CTD PMID:33661552 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in increased expression of GPT protein]]; betanin inhibits the reaction [Cisplatin results in increased expression of GPT protein] CTD PMID:33661552 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP betanin inhibits the reaction [Fructose results in increased expression of INS1 protein] CTD PMID:25559852 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Mir34a microRNA 34a multiple interactions EXP betanin inhibits the reaction [Cisplatin results in increased expression of MIR34A mRNA] CTD PMID:33661552 NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO betanin results in decreased expression of MTOR protein CTD PMID:37401526 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of and affects the localization of NFE2L2 protein]]; betanin inhibits the reaction [Cisplatin results in decreased expression of and affects the localization of NFE2L2 protein] CTD PMID:33661552 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A mRNA]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in increased acetylation of PPARGC1A protein]]; betanin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A mRNA]; betanin inhibits the reaction [Cisplatin results in increased acetylation of PPARGC1A protein] CTD PMID:33661552 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Rps6 ribosomal protein S6 decreases expression ISO betanin results in decreased expression of RPS6 protein CTD PMID:37401526 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased activity of SIRT1 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [betanin inhibits the reaction [Cisplatin results in decreased expression of SIRT1 mRNA]]; betanin inhibits the reaction [Cisplatin results in decreased activity of SIRT1 protein]; betanin inhibits the reaction [Cisplatin results in decreased expression of SIRT1 mRNA] CTD PMID:33661552 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP betanin inhibits the reaction [Fructose results in increased expression of TGFB1 protein] CTD PMID:25559852 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19879
    role 19850
      biological role 19848
        biochemical role 19562
          metabolite 19550
            alkaloid 8029
              betalain 26
                Betanin 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    main group molecular entity 19816
                      s-block molecular entity 19651
                        hydrogen molecular entity 19633
                          hydrides 19147
                            inorganic hydride 18160
                              pnictogen hydride 18150
                                nitrogen hydride 18063
                                  azane 17872
                                    ammonia 17871
                                      organic amino compound 17871
                                        amino acid 16064
                                          non-proteinogenic amino acid 4015
                                            non-proteinogenic alpha-amino acid 3809
                                              betanidin 18
                                                Betanin 18
paths to the root