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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:rheumatoid arthritis pathway
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Accession:PW:0001019 term browser browse the term
Definition:Rheumatoid arthritis is an autoimmune condition characterized by persistent inflammation. Several pro-inflammatory cytokines and chemokines are over-activated.
Synonyms:exact_synonym: atrophic arthritis pathway;   rheumatic arthritis pathway;   rheumatic polyarthritis pathway;   rheumatoid arthritis disease pathway
 related_synonym: KEGG:05323


show annotations for term's descendants           Sort by:
rheumatoid arthritis pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant IEA KEGG rno:05323 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Angpt1 angiopoietin 1 IEA KEGG rno:05323 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 IEA KEGG rno:05323 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 IEA KEGG rno:05323 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895 		JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 IEA KEGG rno:05323 NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 IEA KEGG rno:05323 NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110 		JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B IEA KEGG rno:05323 NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C IEA KEGG rno:05323 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 IEA KEGG rno:05323 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 IEA KEGG rno:05323 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354 		JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 IEA KEGG rno:05323 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434 		JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 IEA KEGG rno:05323 NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A IEA KEGG rno:05323 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 IEA KEGG rno:05323 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 IEA KEGG rno:05323 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 IEA KEGG rno:05323 NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278 		JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 IEA KEGG rno:05323 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D IEA KEGG rno:05323 NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 IEA KEGG rno:05323 NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584 		JBrowse link
G Atp6v1e2 ATPase H+ transporting V1 subunit E2 IEA KEGG rno:05323 NCBI chr 6:7,667,359...7,673,711
Ensembl chr 6:7,667,564...7,672,626 		JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F IEA KEGG rno:05323 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 IEA KEGG rno:05323 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463 		JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 IEA KEGG rno:05323 NCBI chr20:3,587,681...3,591,309
Ensembl chr20:3,587,686...3,590,481 		JBrowse link
G Atp6v1g3 ATPase H+ transporting V1 subunit G3 IEA KEGG rno:05323 NCBI chr13:49,800,256...49,825,247
Ensembl chr13:49,794,222...49,825,247 		JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H IEA KEGG rno:05323 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 IEA KEGG rno:05323 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 IEA KEGG rno:05323 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 IEA KEGG rno:05323 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEA KEGG rno:05323 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cd28 Cd28 molecule IEA KEGG rno:05323 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd80 Cd80 molecule IEA KEGG rno:05323 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule IEA KEGG rno:05323 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Csf1 colony stimulating factor 1 IEA KEGG rno:05323 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf2 colony stimulating factor 2 IEA KEGG rno:05323 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IEA KEGG rno:05323 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Ctsk cathepsin K IEA KEGG rno:05323 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctsl cathepsin L IEA KEGG rno:05323 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEA KEGG rno:05323 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEA KEGG rno:05323 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:05323 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEA KEGG rno:05323 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma IEA KEGG rno:05323 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il11 interleukin 11 IEA KEGG rno:05323 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il15 interleukin 15 IEA KEGG rno:05323 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il18 interleukin 18 IEA KEGG rno:05323 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha IEA KEGG rno:05323 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta IEA KEGG rno:05323 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il23a interleukin 23 subunit alpha IEA KEGG rno:05323 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il6 interleukin 6 IEA KEGG rno:05323 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgal integrin subunit alpha L IEA KEGG rno:05323 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Itgb2 integrin subunit beta 2 IEA KEGG rno:05323 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:05323 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Ltb lymphotoxin beta IEA KEGG rno:05323 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381 		JBrowse link
G Mmp1 matrix metallopeptidase 1 IEA KEGG rno:05323 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp3 matrix metallopeptidase 3 IEA KEGG rno:05323 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Pgf placental growth factor IEA KEGG rno:05323 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685 		JBrowse link
G RT1-Ba RT1 class II, locus Ba IEA KEGG rno:05323 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G RT1-Bb RT1 class II, locus Bb IEA KEGG rno:05323 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Da RT1 class II, locus Da IEA KEGG rno:05323 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 IEA KEGG rno:05323 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G RT1-DMa RT1 class II, locus DMa IEA KEGG rno:05323 NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432 		JBrowse link
G RT1-DMb RT1 class II, locus DMb IEA KEGG rno:05323 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340 		JBrowse link
G RT1-DOa RT1 class II, locus DOa IEA KEGG rno:05323 NCBI chr20:4,753,587...4,756,590
Ensembl chr20:4,753,598...4,756,577 		JBrowse link
G RT1-DOb RT1 class II, locus DOb IEA KEGG rno:05323 NCBI chr20:4,619,418...4,625,627
Ensembl chr20:4,619,816...4,625,667 		JBrowse link
G RT1-Ha RT1 class II, locus Ha IEA KEGG rno:05323 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 IEA KEGG rno:05323 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
G Tek TEK receptor tyrosine kinase IEA KEGG rno:05323 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEA KEGG rno:05323 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEA KEGG rno:05323 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 IEA KEGG rno:05323 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tlr2 toll-like receptor 2 IEA KEGG rno:05323 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 IEA KEGG rno:05323 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor IEA KEGG rno:05323 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A IEA KEGG rno:05323 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfsf11 TNF superfamily member 11 IEA KEGG rno:05323 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf13 TNF superfamily member 13 IEA KEGG rno:05323 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042 		JBrowse link
G Tnfsf13b TNF superfamily member 13b IEA KEGG rno:05323 NCBI chr16:79,462,406...79,492,888
Ensembl chr16:79,462,402...79,492,693 		JBrowse link
G Vegfa vascular endothelial growth factor A IEA KEGG rno:05323 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfb vascular endothelial growth factor B IEA KEGG rno:05323 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    disease pathway 1954
      musculoskeletal disease pathway 171
        arthritis pathway 116
          rheumatoid arthritis pathway 79
paths to the root