Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine
go back to main search page
Accession:CHEBI:92246 term browser browse the term
Definition:An aralkylamine that has formula C13H22N4O3S.
Synonyms:related_synonym: Formula=C13H22N4O3S;   InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3;   InChIKey=VMXUWOKSQNHOCA-UHFFFAOYSA-N;   SMILES=CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C;   ranitidine HCl;   ranitidine hydrochloride;   zantac;   zenetac
 xref: CAS:66357-35-5;   Drug_Central:2358;   LINCS:LSM-2298
 xref_mesh: MESH:D011899


show annotations for term's descendants           Sort by:
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) multiple interactions EXP
ISO		 Ranitidine binds to and results in decreased activity of ACHE protein; Ranitidine inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]
Ranitidine affects the reaction [Paraoxon results in decreased activity of ACHE protein]		 CTD PMID:15669026 PMID:15669039 PMID:16193528 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACKR3 atypical chemokine receptor 3 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ACKR3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ACKR3 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ACKR3 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 2:236,537,122...236,582,354
Ensembl chr 2:236,567,787...236,582,354 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ADAMTS1 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ADAMTS1 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ADAMTS1 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ALB albumin multiple interactions ISO [Ranitidine co-treated with Diclofenac] results in decreased expression of ALB protein; Quercetin inhibits the reaction [[Ranitidine co-treated with Diclofenac] results in decreased expression of ALB protein] CTD PMID:28400101 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ALDOA mRNA CTD PMID:16415329 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G AMOTL2 angiomotin like 2 multiple interactions ISO Ranitidine inhibits the reaction [Lipopolysaccharides results in increased expression of AMOTL2 mRNA] CTD PMID:16415329 NCBI chr 3:134,355,345...134,375,417
Ensembl chr 3:134,355,347...134,375,479 		JBrowse link
G ARHGEF11 Rho guanine nucleotide exchange factor 11 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ARHGEF11 mRNA CTD PMID:16415329 NCBI chr 1:156,934,840...157,046,903
Ensembl chr 1:156,934,840...157,046,903 		JBrowse link
G ATF3 activating transcription factor 3 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ATF3 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ATF3 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ATP1B1 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ATP1B1 mRNA]; Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of ATP1B1 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO		 Ranitidine inhibits the reaction [Rotenone results in increased expression of BAX protein]
Ranitidine inhibits the reaction [Aspirin results in increased expression of BAX protein]		 CTD PMID:19723537 PMID:30885738 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCHE butyrylcholinesterase multiple interactions EXP Ranitidine binds to and results in decreased activity of BCHE protein; Ranitidine inhibits the reaction [Paraoxon results in decreased activity of BCHE protein] CTD PMID:15669026 PMID:16193528 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP Ranitidine inhibits the reaction [Rotenone results in decreased expression of BCL2 protein] CTD PMID:19723537 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of BHLHE40 mRNA] CTD PMID:16415329 NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323 		JBrowse link
G BMP2 bone morphogenetic protein 2 multiple interactions ISO Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of BMP2 mRNA] CTD PMID:16415329 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BNIP3 BCL2 interacting protein 3 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of BNIP3 mRNA CTD PMID:16401727 PMID:16415329 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of BTG2 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of BTG2 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602 		JBrowse link
G CALCA calcitonin related polypeptide alpha increases expression EXP Ranitidine results in increased expression of CALCA protein CTD PMID:12495560 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP
ISO		 Ranitidine inhibits the reaction [Rotenone results in increased cleavage of and results in increased activity of CASP3 protein]
Ranitidine inhibits the reaction [Aspirin results in increased expression of CASP3 mRNA]; Ranitidine inhibits the reaction [Aspirin results in increased expression of CASP3 protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of CASP3 mRNA]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of CASP3 protein]		 CTD PMID:19723537 PMID:28648817 PMID:29523851 PMID:30580614 PMID:30885738 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 multiple interactions EXP Ranitidine inhibits the reaction [Rotenone results in increased cleavage of CASP9 protein] CTD PMID:19723537 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Ranitidine inhibits the reaction [Indomethacin results in increased activity of CAT protein] CTD PMID:16169175 PMID:16397915 PMID:17895592 PMID:18087811 PMID:18726076 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCNL1 cyclin L1 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CCNL1 mRNA] CTD PMID:16415329 NCBI chr 3:157,143,121...157,160,147
Ensembl chr 3:157,146,508...157,160,760 		JBrowse link
G CD80 CD80 molecule multiple interactions EXP Ranitidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein]] CTD PMID:12538815 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CDK6 cyclin dependent kinase 6 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of CDK6 mRNA CTD PMID:16415329 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CREM cAMP responsive element modulator multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CREM mRNA] CTD PMID:16415329 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958 		JBrowse link
G CSF3 colony stimulating factor 3 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA] CTD PMID:16401727 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CTSL cathepsin L multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CTSL mRNA CTD PMID:16415329 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 decreases expression ISO Ranitidine results in decreased expression of CXCL1 protein CTD PMID:12023551 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CXCL2 mRNA; [Ranitidine co-treated with Lipopolysaccharides] results in increased expression of CXCL2 protein; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CXCL2 mRNA]; Heparin inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 protein]]; Pentoxifylline inhibits the reaction [[Ranitidine co-treated with Lipopolysaccharides] results in increased expression of CXCL2 protein]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 protein] CTD PMID:16401727 PMID:16415329 PMID:17698507 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in decreased expression of DDAH1 mRNA] CTD PMID:29523851 NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of DDIT4 mRNA CTD PMID:16415329 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DIO3 iodothyronine deiodinase 3 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of DIO3 mRNA] CTD PMID:16415329 NCBI chr14:101,561,495...101,563,452
Ensembl chr14:101,560,139...101,563,452 		JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of DUSP1 mRNA CTD PMID:16415329 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G EFNA1 ephrin A1 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of EFNA1 mRNA] CTD PMID:16415329 NCBI chr 1:155,127,876...155,134,899
Ensembl chr 1:155,127,876...155,134,899 		JBrowse link
G EGFL7 EGF like domain multiple 7 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of EGFL7 mRNA CTD PMID:16415329 NCBI chr 9:136,658,856...136,672,678
Ensembl chr 9:136,658,856...136,672,678 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of EGLN3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of EGLN3 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774 		JBrowse link
G EGR1 early growth response 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of EGR1 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of F3 mRNA] CTD PMID:16415329 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G FGF23 fibroblast growth factor 23 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of FGF23 mRNA CTD PMID:16415329 NCBI chr12:4,368,227...4,379,712
Ensembl chr12:4,368,227...4,379,712 		JBrowse link
G FMO3 flavin containing dimethylaniline monoxygenase 3 affects metabolic processing EXP FMO3 protein affects the metabolism of Ranitidine CTD PMID:15286053 NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of FOS mRNA CTD PMID:16415329 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of FOSL2 mRNA] CTD PMID:16415329 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G FOXQ1 forkhead box Q1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of FOXQ1 mRNA CTD PMID:16415329 NCBI chr 6:1,312,098...1,314,758
Ensembl chr 6:1,312,098...1,314,758 		JBrowse link
G FST follistatin multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of FST mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of FST mRNA] CTD PMID:16415329 NCBI chr 5:53,480,629...53,487,134
Ensembl chr 5:53,480,626...53,487,134 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GADD45A mRNA CTD PMID:16415329 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GAST gastrin affects expression
multiple interactions		 EXP
ISO		 Ranitidine affects the expression of GAST protein
Ranitidine inhibits the reaction [GAST protein modified form results in increased secretion of Acids]		 CTD PMID:2470453 PMID:12503773 NCBI chr17:41,712,331...41,715,969
Ensembl chr17:41,712,331...41,715,969 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GOT1 mRNA CTD PMID:16415329 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624 		JBrowse link
G GZMB granzyme B multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GZMB mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GZMB mRNA] CTD PMID:16401727 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267 		JBrowse link
G H2AC25 H2A clustered histone 25 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of H2A mRNA CTD PMID:16415329 NCBI chr 1:228,457,364...228,457,873
Ensembl chr 1:228,434,777...228,457,873 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in decreased expression of HMOX1 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of HMOX1 mRNA] CTD PMID:16415329 PMID:30580614 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of HNF4A mRNA CTD PMID:16415329 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HOMER1 homer scaffold protein 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of HOMER1 mRNA CTD PMID:16415329 NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134 		JBrowse link
G HOXA5 homeobox A5 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of HOXA5 mRNA CTD PMID:16415329 NCBI chr 7:27,141,052...27,143,681
Ensembl chr 7:27,141,052...27,143,681 		JBrowse link
G HRH2 histamine receptor H2 multiple interactions
decreases activity		 EXP
ISO		 [Ranitidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin; Ranitidine binds to and results in decreased activity of HRH2 protein; Ranitidine inhibits the reaction [tiotidine binds to HRH2 protein]
Ranitidine results in decreased activity of HRH2 protein
Ranitidine binds to and results in decreased activity of HRH2 protein; Ranitidine inhibits the reaction [Dimaprit binds to and results in increased activity of HRH2 protein]; Ranitidine inhibits the reaction [Melitten results in increased activity of HRH2 protein]		 CTD PMID:6106871 PMID:6835285 PMID:7512805 PMID:9681472 PMID:9819373 More... NCBI chr 5:175,658,071...175,710,756
Ensembl chr 5:175,658,030...175,710,756 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of HSPA1A mRNA CTD PMID:16415329 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPB8 heat shock protein family B (small) member 8 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of HSPB8 mRNA] CTD PMID:16415329 NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] CTD PMID:11752121 PMID:12538815 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID2 inhibitor of DNA binding 2 multiple interactions ISO Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of ID2 mRNA] CTD PMID:16415329 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G ID4 inhibitor of DNA binding 4 multiple interactions ISO Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of ID4 mRNA] CTD PMID:16415329 NCBI chr 6:19,837,370...19,842,197
Ensembl chr 6:19,837,370...19,842,197 		JBrowse link
G IFNG interferon gamma multiple interactions EXP
ISO		 Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein]]
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Ranitidine; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IFNG protein]		 CTD PMID:10569698 PMID:11752121 PMID:16415329 PMID:17698507 PMID:19362101 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IFRD1 interferon related developmental regulator 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IFRD1 mRNA CTD PMID:16415329 NCBI chr 7:112,423,174...112,477,203
Ensembl chr 7:112,422,887...112,481,017 		JBrowse link
G IGSF10 immunoglobulin superfamily member 10 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IGSF10 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IGSF10 mRNA] CTD PMID:16401727 NCBI chr 3:151,432,432...151,619,925
Ensembl chr 3:151,425,384...151,461,061 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO
EXP		 Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]]		 CTD PMID:11752121 PMID:17698507 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12A interleukin 12A multiple interactions EXP Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Ranitidine inhibits the reaction [Histamine results in decreased expression of IL12A protein] CTD PMID:9819373 PMID:11752121 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL12B interleukin 12B multiple interactions EXP Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Ranitidine inhibits the reaction [Histamine results in decreased expression of IL12B protein] CTD PMID:9819373 PMID:11752121 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL18 interleukin 18 multiple interactions EXP Ranitidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]] CTD PMID:11752121 PMID:16723495 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Ranitidine CTD PMID:19362101 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions		 ISO Ranitidine results in increased expression of IL1B protein
Pentoxifylline inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL1B protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of IL1B mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]		 CTD PMID:15265675 PMID:17698507 PMID:30580614 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL4 interleukin 4 multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in increased expression of IL4 protein] CTD PMID:29523851 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IL6 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IL6 mRNA]; Pentoxifylline inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of IL6 protein]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:15265675 PMID:16401727 PMID:16415329 PMID:17698507 PMID:28648817 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHBE inhibin subunit beta E multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of INHBE mRNA CTD PMID:16415329 NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280 		JBrowse link
G INSIG1 insulin induced gene 1 multiple interactions ISO Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of INSIG1 mRNA] CTD PMID:16415329 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G INSIG2 insulin induced gene 2 multiple interactions ISO Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of INSIG2 mRNA] CTD PMID:16415329 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997 		JBrowse link
G IRS2 insulin receptor substrate 2 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IRS2 mRNA] CTD PMID:16415329 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G ITPKC inositol-trisphosphate 3-kinase C multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ITPKC mRNA] CTD PMID:16415329 NCBI chr19:40,717,112...40,740,860
Ensembl chr19:40,717,112...40,740,860 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of JUN mRNA] CTD PMID:16415329 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KLF4 KLF transcription factor 4 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of KLF4 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of KLF4 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482 		JBrowse link
G KLF6 KLF transcription factor 6 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of KLF6 mRNA] CTD PMID:16415329 NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP Ranitidine inhibits the reaction [Rotenone results in increased phosphorylation of MAPK1 protein] CTD PMID:19723537 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP Ranitidine inhibits the reaction [Rotenone results in increased phosphorylation of MAPK3 protein] CTD PMID:19723537 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 multiple interactions
increases expression		 ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of MAPKAPK2 mRNA
Ranitidine results in increased expression of MAPKAPK2 mRNA		 CTD PMID:16401727 PMID:16415329 NCBI chr 1:206,684,905...206,734,281
Ensembl chr 1:206,684,905...206,734,281 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions ISO Ranitidine inhibits the reaction [Ethanol results in increased secretion of and results in increased activity of MMP9 protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of MMP9 protein] CTD PMID:17603938 PMID:29523851 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase multiple interactions
decreases expression		 ISO Ranitidine inhibits the reaction [Aspirin results in increased expression of MPO protein]; Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]
Ranitidine results in decreased expression of MPO protein		 CTD PMID:12023551 PMID:16169175 PMID:17895592 PMID:18726076 PMID:28648817 More... NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of MYC mRNA] CTD PMID:16415329 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NEDD4L mRNA CTD PMID:16415329 NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in decreased expression of NFE2L2 mRNA] CTD PMID:28648817 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NGF nerve growth factor multiple interactions ISO Ranitidine inhibits the reaction [Capsaicin results in increased expression of NGF protein] CTD PMID:15265675 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NOCT nocturnin multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NOCT mRNA CTD PMID:16415329 NCBI chr 4:139,015,781...139,045,939
Ensembl chr 4:139,015,781...139,045,939 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein] CTD PMID:16169175 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in decreased expression of NQO1 protein] CTD PMID:30580614 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NR4A1 mRNA CTD PMID:16415329 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NUPR1 mRNA CTD PMID:16415329 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008 		JBrowse link
G P4HA1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of P4HA1 mRNA CTD PMID:16415329 NCBI chr10:73,007,217...73,096,866
Ensembl chr10:73,007,217...73,096,974 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions EXP Ranitidine inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:19723537 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PFKL phosphofructokinase, liver type multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of PFKL mRNA CTD PMID:16415329 NCBI chr21:44,300,053...44,327,373
Ensembl chr21:44,300,051...44,327,376 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of PPP1R15A mRNA] CTD PMID:16415329 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059 		JBrowse link
G PREB prolactin regulatory element binding multiple interactions ISO Ranitidine inhibits the reaction [Lipopolysaccharides results in increased expression of PREB mRNA] CTD PMID:16415329 NCBI chr 2:27,130,756...27,134,636
Ensembl chr 2:27,130,756...27,134,666 		JBrowse link
G PRL prolactin affects expression
increases secretion		 EXP Ranitidine affects the expression of PRL protein
Ranitidine results in increased secretion of PRL protein		 CTD PMID:7878608 PMID:9037573 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of PTGS2 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of PTGS2 mRNA]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:16401727 PMID:16415329 PMID:29523851 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PVR PVR cell adhesion molecule multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of PVR mRNA] CTD PMID:16415329 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of RAC1 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of RAC1 mRNA] CTD PMID:16401727 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO Ranitidine inhibits the reaction [Indomethacin results in increased expression of RELA mRNA]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of RELA protein] CTD PMID:28648817 PMID:30580614 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G REN renin affects activity EXP Ranitidine affects the activity of REN protein CTD PMID:1972605 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G RGS2 regulator of G protein signaling 2 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of RGS2 mRNA] CTD PMID:16415329 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275 		JBrowse link
G RGS4 regulator of G protein signaling 4 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of RGS4 mRNA] CTD PMID:16415329 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802 		JBrowse link
G RHOB ras homolog family member B multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ARHB mRNA] CTD PMID:16415329 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SERPINE1 mRNA; Heparin inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]]; Pentoxifylline inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein] CTD PMID:16401727 PMID:16415329 PMID:17698507 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SH2B2 SH2B adaptor protein 2 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of APS mRNA CTD PMID:16415329 NCBI chr 7:102,285,141...102,321,711
Ensembl chr 7:102,285,091...102,321,711 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of SHANK3 mRNA CTD PMID:16415329 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,408...50,733,212 		JBrowse link
G SIK1 salt inducible kinase 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SIK1 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SIK1 mRNA] CTD PMID:16415329 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131 		JBrowse link
G SLC16A6 solute carrier family 16 member 6 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC16A6 mRNA CTD PMID:16415329 NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267 		JBrowse link
G SLC20A1 solute carrier family 20 member 1 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC20A1 mRNA CTD PMID:16415329 NCBI chr 2:112,645,939...112,663,825
Ensembl chr 2:112,645,939...112,663,825 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 multiple interactions
affects transport
increases uptake		 EXP
ISO		 Ranitidine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
SLC22A1 protein affects the transport of Ranitidine
SLC22A1 protein results in increased uptake of Ranitidine		 CTD PMID:16006492 PMID:16141367 PMID:16263091 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 increases uptake
multiple interactions		 EXP
ISO		 SLC22A2 protein results in increased uptake of Ranitidine
Ranitidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]		 CTD PMID:16006492 PMID:16141367 PMID:16263091 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
G SLC22A3 solute carrier family 22 member 3 multiple interactions EXP Ranitidine inhibits the reaction [SLC22A3 protein affects the transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16141367 PMID:16263091 NCBI chr 6:160,348,378...160,452,577
Ensembl chr 6:160,348,378...160,452,577 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 increases uptake EXP SLC22A6 protein results in increased uptake of Ranitidine CTD PMID:16006492 NCBI chr11:62,976,597...62,984,967
Ensembl chr11:62,936,385...62,984,967 		JBrowse link
G SLC22A7 solute carrier family 22 member 7 increases uptake EXP SLC22A7 protein results in increased uptake of Ranitidine CTD PMID:16006492 NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 increases uptake
multiple interactions		 EXP
ISO		 SLC22A8 protein results in increased uptake of Ranitidine
Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Ranitidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Ranitidine]; Ranitidine inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]		 CTD PMID:15319347 PMID:16006492 NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SLC2A1 mRNA] CTD PMID:16415329 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC38A2 solute carrier family 38 member 2 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SLC38A2 mRNA] CTD PMID:16415329 NCBI chr12:46,358,188...46,372,773
Ensembl chr12:46,358,188...46,372,773 		JBrowse link
G SLC47A1 solute carrier family 47 member 1 multiple interactions EXP Ranitidine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr17:19,533,854...19,579,034
Ensembl chr17:19,495,385...19,579,034 		JBrowse link
G SLC47A2 solute carrier family 47 member 2 multiple interactions EXP Ranitidine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr17:19,678,317...19,718,979
Ensembl chr17:19,678,288...19,718,979 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC5A3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC5A3 mRNA] CTD PMID:16401727 NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260 		JBrowse link
G SLK STE20 like kinase multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLK mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLK mRNA] CTD PMID:16401727 NCBI chr10:103,967,140...104,029,233
Ensembl chr10:103,967,140...104,029,233 		JBrowse link
G SPHK1 sphingosine kinase 1 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SPHK1 mRNA] CTD PMID:16415329 NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860 		JBrowse link
G TAC1 tachykinin precursor 1 increases expression EXP Ranitidine results in increased expression of TAC1 protein CTD PMID:12495560 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472 		JBrowse link
G TFRC transferrin receptor multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TFRC mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TFRC mRNA] CTD PMID:16401727 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO		 Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Ranitidine; Ranitidine inhibits the reaction [Aspirin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]		 CTD PMID:11752121 PMID:12023551 PMID:12538815 PMID:15265675 PMID:17698507 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of TNFAIP6 mRNA] CTD PMID:16415329 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046 		JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of TNFRSF12A mRNA] CTD PMID:16415329 NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383 		JBrowse link
G TPM3 tropomyosin 3 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TPM3 mRNA CTD PMID:16415329 NCBI chr 1:154,155,308...154,192,100
Ensembl chr 1:154,155,308...154,194,648 		JBrowse link
G TRAK2 trafficking kinesin protein 2 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TRAK2 mRNA CTD PMID:16415329 NCBI chr 2:201,377,207...201,451,458
Ensembl chr 2:201,377,207...201,451,500 		JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of UBE2B mRNA CTD PMID:16415329 NCBI chr 5:134,371,569...134,392,108
Ensembl chr 5:134,371,184...134,392,108 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of VEGFA mRNA CTD PMID:16415329 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G ZBTB10 zinc finger and BTB domain containing 10 multiple interactions ISO [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ZBTB10 mRNA CTD PMID:16415329 NCBI chr 8:80,485,593...80,526,265
Ensembl chr 8:80,485,619...80,526,265 		JBrowse link
G ZFYVE27 zinc finger FYVE-type containing 27 multiple interactions ISO Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ZFYVE27 mRNA] CTD PMID:16415329 NCBI chr10:97,737,128...97,760,895
Ensembl chr10:97,737,121...97,760,907 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26089
    role 26005
      application 25223
        NMR chemical shift reference compound 20450
          ammonia 19945
            organic amino compound 19965
              aralkylamino compound 1031
                aralkylamine 172
                  N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine 136
Path 2
Term Annotations click to browse term
  CHEBI ontology 26089
    subatomic particle 26064
      composite particle 26064
        hadron 26064
          baryon 26064
            nucleon 26016
              atomic nucleus 26064
                atom 26064
                  main group element atom 25891
                    main group molecular entity 25891
                      s-block molecular entity 25200
                        hydrogen molecular entity 24793
                          hydrides 22993
                            inorganic hydride 20521
                              pnictogen hydride 20462
                                nitrogen hydride 20240
                                  azane 19966
                                    ammonia 19945
                                      organic amino compound 19965
                                        amine 8481
                                          alkylamines 190
                                            aralkylamine 172
                                              N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine 136
paths to the root