Vamp7 (vesicle-associated membrane protein 7) - Rat Genome Database

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Gene: Vamp7 (vesicle-associated membrane protein 7) Rattus norvegicus
Analyze
Symbol: Vamp7
Name: vesicle-associated membrane protein 7
RGD ID: 621558
Description: Enables SNAP receptor activity and syntaxin binding activity. Involved in several processes, including Golgi vesicle transport; regulated exocytosis; and triglyceride transport. Located in several cellular components, including bounding membrane of organelle; filopodium; and perinuclear region of cytoplasm. Part of SNARE complex. Is active in hippocampal mossy fiber to CA3 synapse and synaptic vesicle membrane. Orthologous to human VAMP7 (vesicle associated membrane protein 7); PARTICIPATES IN autophagy pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Sybl1; synaptobrevin-like 1; synaptobrevin-like protein 1; VAMP-7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81221,842,206 - 21,958,556 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1221,842,228 - 21,958,552 (+)EnsemblGRCr8
mRatBN7.21216,728,486 - 16,764,261 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1216,728,524 - 16,764,097 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1217,566,927 - 17,592,992 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,190,658 - 18,216,722 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,244,056 - 17,270,121 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,996,566 - 19,033,714 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,996,591 - 19,030,381 (+)Ensemblrn6Rnor6.0
Rnor_5.01220,989,825 - 21,090,967 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41217,248,700 - 17,278,193 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1218,674,387 - 18,700,778 (+)NCBICelera
RGSC_v3.11217,238,221 - 17,267,715 (-)NCBI
Cytogenetic Map12q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. VAMP-7 mediates vesicular transport from endosomes to lysosomes. Advani RJ, etal., J Cell Biol. 1999 Aug 23;146(4):765-76.
2. Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission. Bal M, etal., Neuron. 2013 Nov 20;80(4):934-46. doi: 10.1016/j.neuron.2013.08.024. Epub 2013 Nov 7.
3. TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. Braun V, etal., EMBO J. 2004 Oct 27;23(21):4166-76. Epub 2004 Oct 7.
4. A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery. Burgo A, etal., Dev Cell. 2012 Jul 17;23(1):166-80. doi: 10.1016/j.devcel.2012.04.019. Epub 2012 Jun 14.
5. Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. Burgo A, etal., EMBO Rep. 2009 Oct;10(10):1117-24. doi: 10.1038/embor.2009.186. Epub 2009 Sep 11.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Rat basophilic leukemia cells express syntaxin-3 and VAMP-7 in granule membranes. Hibi T, etal., Biochem Biophys Res Commun 2000 Apr 29;271(1):36-41.
9. Overview of macroautophagy regulation in mammalian cells. Mehrpour M, etal., Cell Res. 2010 Jul;20(7):748-62. Epub 2010 Jun 15.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Tetanus neurotoxin-insensitive vesicle-associated membrane protein localizes to a presynaptic membrane compartment in selected terminal subsets of the rat brain. Muzerelle A, etal., Neuroscience. 2003;122(1):59-75.
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. Pryor PR, etal., EMBO Rep. 2004 Jun;5(6):590-5. Epub 2004 May 7.
14. Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. Rao SK, etal., J Biol Chem. 2004 May 7;279(19):20471-9. Epub 2004 Mar 1.
15. GOA pipeline RGD automated data pipeline
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. The identification of a novel endoplasmic reticulum to Golgi SNARE complex used by the prechylomicron transport vesicle. Siddiqi SA, etal., J Biol Chem. 2006 Jul 28;281(30):20974-82. Epub 2006 May 30.
18. Vesicle-associated membrane protein 7 is expressed in intestinal ER. Siddiqi SA, etal., J Cell Sci. 2006 Mar 1;119(Pt 5):943-50.
19. Molecular anatomy of a trafficking organelle. Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46.
Additional References at PubMed
PMID:10888671   PMID:14758363   PMID:16677249   PMID:17897319   PMID:18042464   PMID:18227281   PMID:18253931   PMID:18321981   PMID:19056867   PMID:19675279   PMID:20582536   PMID:21151919  
PMID:21998198   PMID:22171327   PMID:22188132   PMID:22589474   PMID:22871113   PMID:23217709   PMID:24550300  


Genomics

Comparative Map Data
Vamp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81221,842,206 - 21,958,556 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1221,842,228 - 21,958,552 (+)EnsemblGRCr8
mRatBN7.21216,728,486 - 16,764,261 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1216,728,524 - 16,764,097 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1217,566,927 - 17,592,992 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,190,658 - 18,216,722 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,244,056 - 17,270,121 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,996,566 - 19,033,714 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,996,591 - 19,030,381 (+)Ensemblrn6Rnor6.0
Rnor_5.01220,989,825 - 21,090,967 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41217,248,700 - 17,278,193 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1218,674,387 - 18,700,778 (+)NCBICelera
RGSC_v3.11217,238,221 - 17,267,715 (-)NCBI
Cytogenetic Map12q11NCBI
VAMP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38Y57,067,865 - 57,130,289 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38X155,881,345 - 155,943,769 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblY57,067,747 - 57,130,289 (+)Ensemblhg38GRCh38
GRCh38.p14 EnsemblX155,881,227 - 155,943,769 (+)Ensemblhg38GRCh38
GRCh37Y59,214,014 - 59,276,439 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37X155,111,008 - 155,173,433 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X154,764,207 - 154,826,614 (+)NCBIBuild 36Build 36hg18NCBI36
Build 36Y57,623,407 - 57,685,814 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34Y57,552,143 - 57,614,551NCBI
CeleraX155,267,418 - 155,329,920 (+)NCBICelera
Cytogenetic MapXq28 and Yq12NCBI
HuRefX143,593,932 - 143,656,425 (+)NCBIHuRef
CHM1_1X155,022,569 - 155,085,064 (+)NCBICHM1_1
T2T-CHM13v2.0Y62,306,325 - 62,368,760 (+)NCBIT2T-CHM13v2.0
T2T-CHM13v2.0X154,109,337 - 154,171,772 (+)NCBIT2T-CHM13v2.0
Vamp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic MapX NCBI
Vamp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495559418,727 - 72,654 (-)Ensembl
ChiLan1.0NW_00495559420,496 - 72,648 (-)NCBIChiLan1.0ChiLan1.0
VAMP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X155,861,375 - 155,924,093 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X155,864,983 - 155,927,704 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X145,362,432 - 145,425,097 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X155,257,593 - 155,320,215 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX155,257,185 - 155,320,215 (+)EnsemblpanPan2panpan1.1
VAMP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X123,717,524 - 123,783,781 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX123,717,446 - 123,783,014 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX108,704,682 - 108,769,242 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X126,855,012 - 126,919,587 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX126,855,027 - 126,919,572 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X122,587,142 - 122,652,219 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X125,109,846 - 125,174,616 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X124,840,976 - 124,905,504 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Vamp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X120,561,625 - 120,609,966 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936958345,097 - 393,342 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936958345,055 - 393,384 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VAMP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX125,863,292 - 125,917,225 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X125,863,266 - 125,917,232 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
VAMP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X129,937,026 - 129,984,071 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX129,937,046 - 129,984,119 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606568,040,049 - 68,087,731 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vamp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462498040,843 - 94,528 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462498040,937 - 94,547 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Vamp7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11615,277,986 - 15,303,416 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Vamp7
868 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:78
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000011065
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)122013902826430640Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat

Markers in Region
RH132448  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21216,762,279 - 16,762,460 (+)MAPPERmRatBN7.2
Rnor_6.01219,030,350 - 19,030,530NCBIRnor6.0
Rnor_5.01221,088,987 - 21,089,167UniSTSRnor5.0
RGSC_v3.41217,248,353 - 17,248,533UniSTSRGSC3.4
Celera1218,700,945 - 18,701,125UniSTS
RH 3.4 Map12255.5UniSTS
Cytogenetic Map12q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011065   ⟹   ENSRNOP00000011065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1221,842,228 - 21,877,997 (+)Ensembl
mRatBN7.2 Ensembl1216,728,524 - 16,764,097 (+)Ensembl
Rnor_6.0 Ensembl1218,996,591 - 19,030,381 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000123615   ⟹   ENSRNOP00000098691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1221,842,272 - 21,958,552 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000147613   ⟹   ENSRNOP00000104406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1221,842,228 - 21,916,888 (+)Ensembl
RefSeq Acc Id: NM_053531   ⟹   NP_445983
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81221,842,228 - 21,877,997 (+)NCBI
mRatBN7.21216,728,486 - 16,764,261 (+)NCBI
Rnor_6.01219,003,391 - 19,030,183 (+)NCBI
Rnor_5.01220,989,825 - 21,090,967 (+)NCBI
RGSC_v3.41217,248,700 - 17,278,193 (-)RGD
Celera1218,674,387 - 18,700,778 (+)RGD
Sequence:
RefSeq Acc Id: XM_063271720   ⟹   XP_063127790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81221,842,206 - 21,958,556 (+)NCBI
Protein Sequences
Protein RefSeqs NP_445983 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127790 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF88059 (Get FASTA)   NCBI Sequence Viewer  
  EDL83882 (Get FASTA)   NCBI Sequence Viewer  
  EDL83883 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011065
  ENSRNOP00000011065.2
  ENSRNOP00000098691
GenBank Protein Q9JHW5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445983   ⟸   NM_053531
- UniProtKB: Q9JHW5 (UniProtKB/Swiss-Prot),   A6KSR6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011065   ⟸   ENSRNOT00000011065
RefSeq Acc Id: XP_063127790   ⟸   XM_063271720
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000098691   ⟸   ENSRNOT00000123615
Ensembl Acc Id: ENSRNOP00000104406   ⟸   ENSRNOT00000147613
Protein Domains
Longin   v-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JHW5-F1-model_v2 AlphaFold Q9JHW5 1-220 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698488
Promoter ID:EPDNEW_R9012
Type:initiation region
Name:Vamp7_1
Description:vesicle-associated membrane protein 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01218,996,586 - 18,996,646EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621558 AgrOrtholog
BioCyc Gene G2FUF-19835 BioCyc
Ensembl Genes ENSRNOG00000008372 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011065 ENTREZGENE
  ENSRNOT00000011065.5 UniProtKB/Swiss-Prot
  ENSRNOT00000123615 ENTREZGENE
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot
  Longin domain UniProtKB/Swiss-Prot
InterPro Longin-like_dom_sf UniProtKB/Swiss-Prot
  Longin_dom UniProtKB/Swiss-Prot
  Synaptobrevin UniProtKB/Swiss-Prot
  Synaptobrevin-like_transport UniProtKB/Swiss-Prot
  V_SNARE_CC UniProtKB/Swiss-Prot
KEGG Report rno:85491 UniProtKB/Swiss-Prot
NCBI Gene 85491 ENTREZGENE
PANTHER SNARE PROTEINS UniProtKB/Swiss-Prot
  VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 UniProtKB/Swiss-Prot
Pfam Longin UniProtKB/Swiss-Prot
  Synaptobrevin UniProtKB/Swiss-Prot
PhenoGen Vamp7 PhenoGen
PRINTS SYNAPTOBREVN UniProtKB/Swiss-Prot
PROSITE LONGIN UniProtKB/Swiss-Prot
  SYNAPTOBREVIN UniProtKB/Swiss-Prot
  V_SNARE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008372 RatGTEx
SMART Longin UniProtKB/Swiss-Prot
Superfamily-SCOP SNARE fusion complex UniProtKB/Swiss-Prot
  SSF64356 UniProtKB/Swiss-Prot
UniProt A0ABK0L3N0_RAT UniProtKB/TrEMBL
  A0ABK0LG97_RAT UniProtKB/TrEMBL
  A6KSR6 ENTREZGENE, UniProtKB/TrEMBL
  Q9JHW5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-11 Vamp7  vesicle-associated membrane protein 7  Sybl1  synaptobrevin-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Sybl1  synaptobrevin-like 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Sybl1  synaptobrevin-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to granule membranes 634103