Vamp7 (vesicle associated membrane protein 7)

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Gene: Vamp7 (vesicle associated membrane protein 7) Chinchilla lanigera

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Symbol:

Vamp7

Name:

vesicle associated membrane protein 7

RGD ID:

8760757

Description:

ENCODES a protein that exhibits SNAP receptor activity (ortholog); syntaxin binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); calcium-ion regulated exocytosis (ortholog); endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH autistic disorder (ortholog); head and neck squamous cell carcinoma (ortholog); immunodeficiency 33 (ortholog); FOUND IN apical part of cell (ortholog); azurophil granule membrane (ortholog); cell surface (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

vesicle-associated membrane protein 7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955594	18,727 - 72,654 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955594	20,496 - 72,648 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

head and neck squamous cell carcinoma (ISO)

immunodeficiency 33 (ISO)

papillomavirus infectious disease (ISO)

Splenomegaly (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Cellular Component

apical part of cell (ISO)

azurophil granule membrane (ISO)

cell surface (ISO)

cytoplasm (ISO)

endoplasmic reticulum membrane (ISO)

filopodium (ISO)

Golgi apparatus (ISO)

hippocampal mossy fiber to CA3 synapse (ISO)

intracellular membrane-bounded organelle (ISO)

lamellipodium (ISO)

late endosome membrane (ISO)

lysosomal membrane (ISO)

membrane (ISO)

neuron projection (ISO)

perinuclear region of cytoplasm (ISO)

phagocytic vesicle (ISO)

plasma membrane (ISO)

platelet alpha granule (ISO)

pseudopodium (ISO)

secretory granule (ISO)

secretory granule membrane (ISO)

SNARE complex (ISO)

synaptic vesicle membrane (ISO)

trans-Golgi network (ISO)

transport vesicle (ISO)

Molecular Function

protein binding (ISO)

SNAP receptor activity (ISO)

syntaxin binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

autophagy pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Vamp7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955594	18,727 - 72,654 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955594	20,496 - 72,648 (-)	NCBI	ChiLan1.0	ChiLan1.0

VAMP7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	Y	57,067,865 - 57,130,289 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38	X	155,881,345 - 155,943,769 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	155,881,345 - 155,943,769 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p14 Ensembl	Y	57,067,865 - 57,130,289 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	Y	59,214,014 - 59,276,439 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	X	155,111,008 - 155,173,433 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	Y	57,623,407 - 57,685,814 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 36	X	154,764,207 - 154,826,614 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	Y	57,552,143 - 57,614,551	NCBI
Celera	X	155,267,418 - 155,329,920 (+)	NCBI		Celera
Cytogenetic Map	X	q28 and Yq12	NCBI
HuRef	X	143,593,932 - 143,656,425 (+)	NCBI		HuRef
CHM1_1	X	155,022,569 - 155,085,064 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	154,109,337 - 154,171,772 (+)	NCBI		T2T-CHM13v2.0
T2T-CHM13v2.0	Y	62,306,325 - 62,368,760 (+)	NCBI		T2T-CHM13v2.0

Vamp7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Cytogenetic Map	X		NCBI

Vamp7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	21,842,206 - 21,958,556 (+)	NCBI		GRCr8
mRatBN7.2	12	16,728,486 - 16,764,261 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	16,728,524 - 16,764,097 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	17,566,927 - 17,592,992 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	18,190,658 - 18,216,722 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	17,244,056 - 17,270,121 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	18,996,566 - 19,033,714 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	18,996,591 - 19,030,381 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	20,989,825 - 21,090,967 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	17,248,700 - 17,278,193 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	17,238,221 - 17,267,715 (-)	NCBI
Celera	12	18,674,387 - 18,700,778 (+)	NCBI		Celera
Cytogenetic Map	12	q11	NCBI

VAMP7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	155,861,375 - 155,924,093 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	155,864,983 - 155,927,704 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	145,362,432 - 145,425,097 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	155,257,593 - 155,320,215 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	155,257,185 - 155,320,215 (+)	Ensembl	panpan1.1		panPan2

VAMP7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	123,717,524 - 123,783,781 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	123,717,446 - 123,783,014 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	108,704,682 - 108,769,242 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	126,855,012 - 126,919,587 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	126,855,027 - 126,919,572 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	122,587,142 - 122,652,219 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	125,109,846 - 125,174,616 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	124,840,976 - 124,905,504 (+)	NCBI		UU_Cfam_GSD_1.0

Vamp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	120,561,625 - 120,609,966 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936958	345,055 - 393,384 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VAMP7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	125,863,292 - 125,917,225 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	125,863,266 - 125,917,232 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

VAMP7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	129,937,026 - 129,984,071 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	129,937,046 - 129,984,119 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	68,040,049 - 68,087,731 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vamp7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624980	40,843 - 94,528 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624980	40,937 - 94,547 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005414638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01076411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01076412	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01076413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01208298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000000450 ⟹ ENSCLAP00000000421

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955594	18,727 - 72,654 (-)	Ensembl

RefSeq Acc Id:

XM_005414638 ⟹ XP_005414695

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955594	20,496 - 72,648 (-)	NCBI

Sequence:

show sequence

TTTACACGGAAGTCAGTGGCGTCTAGTTCCATCCGCTTCTGGGAGCCGGCAACCGGCCTCCCTG
GGCTGACCTGCGCCCCTCGGTTCTGAGCCTGTGTTCCCCTAGAGGGTGCCCGGACAGATTGAAG
CCATGGCCATTCTTTTTGCTGTTGTTGCCAGGGGAACCACTATCCTTGCCAAACATGCTTGGTG
TGGAGGAAACTTCCTGGAGGTGACAGAGCAGATTCTGGCAAAGATACCTTCTGAAAATAACAAA
CTAACATATTCACATGGCAATTATTTGTTTCATTACATCTGCCAAGACAGGATTGTATATCTTT
GTATCACTGATGATGATTTTGAACGTTCCCGAGCCTTCAATTTTCTGAATGAAGTAAAGAAGAG
GTTCCAGACTACTTATGGTTCAAGAGCACAGACAGCGCTTCCATATGCCATGAATAGCGAGTTC
TCAAGTGTCCTGGCTGCACAGCTGAAGCATCACTCTGAGAATAAGGGCCTAGACAAAGTGATGG
AGACTCAAGCCCAAGTGGATGAACTGAAAGGAATCATGGTCAGAAATATAGATCTGGTAGCTCA
GCGAGGAGAAAGATTGGAATTATTGATAGATAAAACAGAAAATCTTGTGGATTCATCTGTCACC
TTCAAAACAACCAGCAGAAATCTTGCCCGAGCCATGTGTATGAAGAATATCAAGCTCACCATCA
TCATCATCATCGTATCAATTGTGTTCATCTATATCATTGTATCATCTCTCTGTGGTGGATTTAC
ATGGCCAAGCTGTGTAAAGAAATAGGAACGAAAAAGTTTTCATTAACCAAGAATATAAGAGACA
AAGGAATTAGAAACAATCCATGTGACTCAAGCCTTTCACTACTCAGAAAATTGTCTGCCTGTCT
CTTCAACCCTTTTTTTCACTTTGTCTTGTTTCAATCTTGTTCTATGCCTTCCAGATTTTTCTTT
GTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005414695	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000000421
	ENSCLAP00000000421.1

RefSeq Acc Id:

XP_005414695 ⟸ XM_005414638

- UniProtKB:

A0A8C2UH22 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAILFAVVARGTTILAKHAWCGGNFLEVTEQILAKIPSENNKLTYSHGNYLFHYICQDRIVYLC
ITDDDFERSRAFNFLNEVKKRFQTTYGSRAQTALPYAMNSEFSSVLAAQLKHHSENKGLDKVME
TQAQVDELKGIMVRNIDLVAQRGERLELLIDKTENLVDSSVTFKTTSRNLARAMCMKNIKLTII
IIIVSIVFIYIIVSSLCGGFTWPSCVKK

hide sequence

Ensembl Acc Id:

ENSCLAP00000000421 ⟸ ENSCLAT00000000450

Protein Domains

Longin v-SNARE coiled-coil homology

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000000352	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000000450	ENTREZGENE
	ENSCLAT00000000450.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.110	UniProtKB/TrEMBL
	Longin domain	UniProtKB/TrEMBL
InterPro	Longin-like_dom_sf	UniProtKB/TrEMBL
	Longin_dom	UniProtKB/TrEMBL
	Synaptobrevin	UniProtKB/TrEMBL
	Synaptobrevin-like_transport	UniProtKB/TrEMBL
	V_SNARE_CC	UniProtKB/TrEMBL
NCBI Gene	Vamp7	ENTREZGENE
PANTHER	SNARE PROTEINS	UniProtKB/TrEMBL
	VESICLE-ASSOCIATED MEMBRANE PROTEIN 7	UniProtKB/TrEMBL
Pfam	Longin	UniProtKB/TrEMBL
	Synaptobrevin	UniProtKB/TrEMBL
PRINTS	SYNAPTOBREVN	UniProtKB/TrEMBL
PROSITE	LONGIN	UniProtKB/TrEMBL
	SYNAPTOBREVIN	UniProtKB/TrEMBL
	V_SNARE	UniProtKB/TrEMBL
SMART	Longin	UniProtKB/TrEMBL
Superfamily-SCOP	SNARE fusion complex	UniProtKB/TrEMBL
	SSF64356	UniProtKB/TrEMBL
UniProt	A0A8C2UH22	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Vamp7	vesicle associated membrane protein 7		vesicle-associated membrane protein 7	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations