| 708446 | Ccr1 | C-C motif chemokine receptor 1 | ENCODES a protein that exhibits C-C chemokine binding; C-C chemokine receptor activity (ortholog); chemokine (C-C motif) ligand 5 binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus; cellular response to tumor necrosis factor; cerebellum development; PARTICI PATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH anterior uveitis; colitis; Experimental Arthritis; FOUND IN external side of plasma membrane; neuronal cell body; plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 132433711 | 132439266 | Rat | 259 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 732280 | Ccr1 | C-C motif chemokine receptor 1 | Enables C-C chemokine receptor activity. Involved in negative regulation of innate immune response. Acts upstream of or within inflammatory response; leukocyte chemotaxis; and myeloid cell differentiation. Predicted to be located in neuronal cell body and plasma membrane. Predicted to be active in c ytoplasm and external side of plasma membrane. Is expressed in several structures, including aorta-gonad-mesonephros; extraembryonic component; limb; and liver. Used to study Coronavirus infectious disease. Human ortholog(s) of this gene implicated in allergic contact dermatitis and rheumatoid arthritis. Orthologous to human CCR1 (C-C motif chemokine receptor 1). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 123762163 | 123768729 | Mouse | 326 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1349625 | CCR1 | C-C motif chemokine receptor 1 | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] | 3 | 46201711 | 46208313 | Human | 367 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 11925990 | CCR1 | C-C motif chemokine receptor 1 | ENCODES a protein that exhibits C-C chemokine binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); cellular response to tumor necrosis factor (ortholog); cerebellum development (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); allergic bro nchopulmonary aspergillosis (ortholog); allergic contact dermatitis (ortholog); FOUND IN neuronal cell body (ortholog); plasma membrane (ortholog) | 3 | 46107526 | 46114229 | Bonobo | 118 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12180526 | CCR1 | chemokine (C-C motif) receptor 1 | ENCODES a protein that exhibits C-C chemokine binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); cellular response to tumor necrosis factor (ortholog); cerebellum development (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); allergic bro nchopulmonary aspergillosis (ortholog); allergic contact dermatitis (ortholog); FOUND IN neuronal cell body (ortholog); plasma membrane (ortholog) | 20 | 42421356 | 42427177 | Dog | 115 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 14168318 | CCR1 | C-C motif chemokine receptor 1 | ENCODES a protein that exhibits C-C chemokine binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); cellular response to tumor necrosis factor (ortholog); cerebellum development (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); allergic bro nchopulmonary aspergillosis (ortholog); allergic contact dermatitis (ortholog); FOUND IN neuronal cell body (ortholog); plasma membrane (ortholog); INTERACTS WITH bis(2-chloroethyl) sulfide; dibromine; dichlorine | | | | Pig | 120 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18408735 | CCR1 | C-C motif chemokine receptor 1 | ENCODES a protein that exhibits C-C chemokine binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); cellular response to tumor necrosis factor (ortholog); cerebellum development (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); allergic bro nchopulmonary aspergillosis (ortholog); allergic contact dermatitis (ortholog); FOUND IN neuronal cell body (ortholog); plasma membrane (ortholog) | | | | Green Monkey | 118 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867223 | CCR1 | C-C motif chemokine receptor 1 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 1618934 | Ackr4 | atypical chemokine receptor 4 | Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to be located in early endosome; pla sma membrane; and recycling endosome. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including central nervous system; gut; immune system; male reproductive gland or organ; and sensory organ. Orthologous to human ACKR4 (atypical chemokine receptor 4). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 103974881 | 104003842 | Mouse | 94 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1321787 | Ccr10 | C-C motif chemokine receptor 10 | Enables C-C chemokine receptor activity. Acts upstream of or within chemotaxis and positive regulation of cytosolic calcium ion concentration. Predicted to be located in cell surface; endoplasmic reticulum; and plasma membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CCR10 (C-C motif chemokine receptor 10). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 101063824 | 101066269 | Mouse | 108 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1323461 | Ccrl2 | C-C motif chemokine receptor-like 2 | Enables chemokine receptor binding activity. Involved in inflammatory response. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm and external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and liver and biliary system. Orthologous to human CCRL2 (C-C motif chemokine receptor like 2). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 110883902 | 110886586 | Mouse | 128 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18914581 | LOC101724812 | C-C chemokine receptor type 1 | ENCODES a protein that exhibits C-C chemokine binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); cellular response to tumor necrosis factor (ortholog); cerebellum development (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); allergic bro nchopulmonary aspergillosis (ortholog); allergic contact dermatitis (ortholog); FOUND IN neuronal cell body (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 115 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12646027 | LOC101964209 | C-C chemokine receptor type 1 | ENCODES a protein that exhibits C-C chemokine binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); cellular response to tumor necrosis factor (ortholog); cerebellum development (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); allergic bro nchopulmonary aspergillosis (ortholog); allergic contact dermatitis (ortholog); FOUND IN neuronal cell body (ortholog); plasma membrane (ortholog) | NW_004936596 | 177774 | 183186 | Squirrel | 115 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 8704959 | LOC102029518 | C-C chemokine receptor type 1 | | NW_004955420 | 25759430 | 25764447 | Chinchilla | | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1310716 | Ccr10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits C-C chemokine receptor activity (ortholog); chemokine receptor activity (ortholog); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signal ing pathway; ASSOCIATED WITH status epilepticus (ortholog); FOUND IN cell surface (ortholog); INTERACTS WITH 17beta-estradiol 3-benzoate; acrylamide; bisphenol A | 10 | 86608836 | 86611273 | Rat | 70 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1606584 | CCR10 | C-C motif chemokine receptor 10 | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the dev elopment, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008] | 17 | 42678889 | 42681843 | Human | 69 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 9033386 | Ccr10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits C-C chemokine receptor activity (ortholog); chemokine receptor activity (ortholog); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH status epilepticus (ortholog); FOUND IN cell surface (ortholog ) | NW_004955451 | 16533784 | 16535692 | Chinchilla | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12007860 | CCR10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits C-C chemokine binding (inferred); C-C chemokine receptor activity (inferred); chemokine receptor activity (inferred); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH status epilepticus (ortholog ); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); membrane (inferred) | 17 | 14636529 | 14637750 | Bonobo | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12121736 | CCR10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits C-C chemokine receptor activity (inferred); chemokine receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH status epilept icus (ortholog); FOUND IN cell surface (inferred); membrane (inferred); plasma membrane (inferred) | 9 | 20307755 | 20312613 | Dog | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12515043 | Ccr10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits C-C chemokine binding (inferred); C-C chemokine receptor activity (inferred); chemokine receptor activity (inferred); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH status epilepticus (ortholog ); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); membrane (inferred) | NW_004936490 | 17409819 | 17411135 | Squirrel | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13990024 | CCR10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits C-C chemokine receptor activity (inferred); chemokine receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH status epilept icus (ortholog); FOUND IN cell surface (inferred); membrane (inferred); plasma membrane (inferred) | | | | Pig | 29 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18623966 | CCR10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits C-C chemokine binding (inferred); C-C chemokine receptor activity (inferred); chemokine receptor activity (inferred); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH status epilepticus (ortholog ); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); membrane (inferred) | | | | Green Monkey | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18901436 | Ccr10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits chemokine receptor activity (ortholog); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH status epilepticus (ortholog); FOUND IN cell surface (ortholog) | | | | Naked Mole-Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625870163 | Ccr10 | C-C motif chemokine receptor 10 | ENCODES a protein that exhibits C-C chemokine receptor activity (ortholog); chemokine receptor activity (ortholog); INVOLVED IN chemotaxis (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH status epilepticus (ortholog); FOUND IN cell surface (ortholog ) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626183634 | ccr10 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626188679 | ccr10 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 5130598 | CCR12P | C-C motif chemokine receptor 12, pseudogene | | 13 | 99407926 | 99408968 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1308007 | Ccr1l1 | chemokine (C-C motif) receptor 1-like 1 | ENCODES a protein that exhibits C-C chemokine receptor activity (inferred); chemokine receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN chemokine-mediated signaling pathway (inferred); chemotaxis (inferred); G protein-coupled receptor signaling pathway (inferr ed); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 132467425 | 132478489 | Rat | 30 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1317529 | Ccr1l1 | C-C motif chemokine receptor 1 like 1 | Predicted to enable C-C chemokine binding activity; C-C chemokine receptor activity; and phosphatidylinositol-4,5-bisphosphate phospholipase C activity. Predicted to be involved in several processes, including monocyte chemotaxis; positive regulation of ERK1 and ERK2 cascade; and positive regulation of monocyte chemotaxis. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm and external side of plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in allergic contact dermatitis and rheumatoid arthritis. Orthologous to human CCR1 (C-C motif chemokine receptor 1). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 123776467 | 123786752 | Mouse | 60 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 731576 | Ackr2 | atypical chemokine receptor 2 | Enables C-C chemokine binding activity and C-C chemokine receptor activity. Acts upstream of or within signal transduction. Predicted to be located in several cellular components, including actin filament; cytosol; and nucleus. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; retina; and trophoblast giant cell. Orthologous to human ACKR2 (atypical chemokine receptor 2). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 121727421 | 121740177 | Mouse | 111 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1353783 | ACKR2 | atypical chemokine receptor 2 | This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expr essed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008] | 3 | 42809445 | 42867286 | Human | 102 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1602221 | ACKR4 | atypical chemokine receptor 4 | The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013] | 3 | 132597270 | 132602644 | Human | 86 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 14174679 | ACKR4 | atypical chemokine receptor 4 | ENCODES a protein that exhibits chemokine binding (inferred); chemokine receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN chemokine-mediated signaling pathway (inferred); chemotaxis (inferred); G protein-coupled receptor signaling pathway (inferred); ASSOCIATE D WITH Spontaneous Abortions (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 24 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321539 | CCL15 | C-C motif chemokine ligand 15 | This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor typ e 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14). [provided by RefSeq, Jan 2013] | 17 | 35997582 | 36001553 | Human | 184 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 11974166 | CCL23 | C-C motif chemokine ligand 23 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); CCR1 chemokine receptor binding (inferred); chemokine activity (inferred); INVOLVED IN negative regulation of myoblast differentiation (ortholog); ASSOCIATED WITH allergic disease (orthol og); brain ischemia (ortholog); hepatocellular carcinoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 17 | 20778008 | 20782929 | Bonobo | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 12097610 | CCL23 | chemokine (C-C motif) ligand 23 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); INVOLVED IN cell chemotaxis (inferred); chemotaxis (inferred); immune response (inferred); ASSOCIATED WITH malignant mesothelioma (ortholog); FOUND IN extracellular region (inferred); ex tracellular space (inferred) | 9 | 37763342 | 37767011 | Dog | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 3647 | Ccl3 | C-C motif chemokine ligand 3 | ENCODES a protein that exhibits chemokine activity; CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); INVOLVED IN leukocyte chemotaxis; neutrophil chemotaxis; positive regulation of cytosolic calcium ion concentration; PARTI CIPATES IN interleukin-12 signaling pathway; Chagas disease pathway; chemokine mediated signaling pathway; ASSOCIATED WITH anterior uveitis; Chagas disease; colon cancer; FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular region (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 10 | 68948889 | 68950439 | Rat | 680 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 735784 | CCL3 | C-C motif chemokine ligand 3 | This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associat ed with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010] | 17 | 36088256 | 36090143 | Human | 628 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 13936411 | CCL3L1 | chemokine (C-C motif) ligand 3-like 1 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN astrocyte cell migration (ortholog); calcium ion transport (ortholog); calcium-mediated signa ling (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular space (ortholog) | | | | Pig | 148 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620441 | Ccl4 | C-C motif chemokine ligand 4 | ENCODES a protein that exhibits chemokine activity; CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); INVOLVED IN leukocyte chemotaxis; positive regulation of tumor necrosis factor production; positive regulation of vascular permeability; PARTICIPATES IN interleukin-12 signaling pathway; chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Acute Lung Injury; anti-basement membrane glomerulonephritis; Escherichia Coli Infections; FOUND IN extracellular space (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 68963893 | 68965728 | Rat | 427 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 12161695 | CCL4 | chemokine (C-C motif) ligand 4 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemokine activity (ortholog); INVOLVED IN cellular response to xenobiotic stimulus (ortholog); leukocyte chemotaxis (ortholog); positive regu lation of calcium ion transport (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH acquired immunodeficiency syndrome (ortholog); Acute Liver Failure (ortholog); Acute Lung Injury (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH bisphenol A | 9 | 37681342 | 37682691 | Dog | 91 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 14200903 | CCL4 | C-C motif chemokine ligand 4 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemokine activity (ortholog); INVOLVED IN cellular response to xenobiotic stimulus (ortholog); leukocyte chemotaxis (ortholog); positive regu lation of calcium ion transport (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH acquired immunodeficiency syndrome (ortholog); Acute Liver Failure (ortholog); Acute Lung Injury (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH bifenthrin; prostaglandin F2alpha | | | | Pig | 93 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 69069 | Ccl5 | C-C motif chemokine ligand 5 | ENCODES a protein that exhibits chemokine activity; heparin binding; CCR1 chemokine receptor binding (ortholog); INVOLVED IN cellular response to alkyl hydroperoxide; cellular response to amino acid stimulus; cellular response to cytokine stimulus; PARTICIPATES IN syndecan signaling pathway; Chagas disease pathway; chemokine mediated signaling pathway; ASSOCIATED WITH alcoholic hepatitis; allergic conjunctivitis; Animal Toxoplasmosis; FOUND IN extracellular space; cytoplasm (ortholog); membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 68820330 | 68824906 | Rat | 907 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 69127 | Ccl5 | C-C motif chemokine ligand 5 | Enables CCR1 chemokine receptor binding activity. Involved in negative regulation of macrophage apoptotic process and positive regulation of monocyte chemotaxis. Acts upstream of or within inflammatory response; positive regulation of epithelial cell proliferati on; and response to tumor necrosis factor. Located in cytoplasm and extracellular space. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; liver; and retina. Human ortholog(s) of this gene implicated in several diseases, including hepatitis B; hepatitis C; liver disease (multiple); pulmonary tuberculosis; and severe acute respiratory syndrome. Orthologous to human CCL5 (C-C motif chemokine ligand 5). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 83416604 | 83421344 | Mouse | 998 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8766000 | Ccl5 | C-C motif chemokine ligand 5 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN calcium ion transport (ortholog); cell-cell signaling (ortholog); cellular response to alkyl hydroperoxide (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); membrane (ortholog) | NW_004955481 | 10293758 | 10301118 | Chinchilla | 271 | description | gene, protein-coding, MODEL [RefSeq] |
| 12163122 | CCL5 | C-C motif chemokine ligand 5 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN calcium ion transport (ortholog); cell-cell signaling (ortholog); cellular response to alkyl hydroperoxide (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); membrane (ortholog) | 9 | 37817409 | 37823852 | Dog | 285 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18603395 | CCL5 | C-C motif chemokine ligand 5 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN calcium ion transport (ortholog); cell-cell signaling (ortholog); cellular response to alkyl hydroperoxide (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); membrane (ortholog) | | | | Green Monkey | 271 | description | gene, protein-coding, MODEL [RefSeq] |
| 18933455 | Ccl5 | C-C motif chemokine ligand 5 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN calcium ion transport (ortholog); cell-cell signaling (ortholog); cellular response to alkyl hydroperoxide (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); membrane (ortholog) | | | | Naked Mole-Rat | 283 | description | gene, protein-coding, MODEL [RefSeq] |
| 20866219 | CCL5 | C-C motif chemokine ligand 5 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); CCR1 chemokine receptor binding (inferred); CCR5 chemokine receptor binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cal cium ion transport (inferred); cell chemotaxis (inferred); FOUND IN extracellular region (inferred); extracellular space (inferred); membrane (inferred) | | | | Green Monkey | 72 | description | gene, protein-coding |
| 626071345 | Ccl5 | C-C motif chemokine ligand 5 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN calcium ion transport (ortholog); cell-cell signaling (ortholog); cellular response to alkyl hydroperoxide (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); membrane (ortholog) | | | | Black Rat | 271 | description | gene, protein-coding, MODEL [RefSeq] |
| 1553178 | Ccl6 | C-C motif chemokine ligand 6 | Predicted to enable CCR1 chemokine receptor binding activity; chemoattractant activity; and chemokine activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; cell chemotaxis; and chemokine-mediated signaling pathway. Predicted to be active in extracellular space. Is expressed in several structures, including brain; liver; and retina nuclear layer. Orthologous to human CCL15 (C-C motif chemokine ligand 15) and CCL23 (C-C motif chemokine ligand 23). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 83478712 | 83483913 | Mouse | 216 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359152 | Ccl7 | C-C motif chemokine ligand 7 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR2 chemokine receptor binding (ortholog); chemokine activity (ortholog); INVOLVED IN cellular response to ethanol; response to gamma radiation; cytoskeleton organization (ortholog); PA RTICIPATES IN chemokine mediated signaling pathway; ASSOCIATED WITH bronchiolitis obliterans; Experimental Liver Cirrhosis; glomerulonephritis; FOUND IN extracellular space (ortholog); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 67514095 | 67515945 | Rat | 354 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12359054 | CCL7 | C-C motif chemokine ligand 7 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR2 chemokine receptor binding (ortholog); INVOLVED IN cellular response to ethanol (ortholog); cytoskeleton organization (ortholog); positive regulation of inflammatory response (ortho log); ASSOCIATED WITH allergic conjunctivitis (ortholog); allergic disease (ortholog); asthma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 9 | 38994638 | 38996103 | Dog | 70 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321540 | Ccl9 | C-C motif chemokine ligand 9 | Predicted to enable CCR1 chemokine receptor binding activity; chemoattractant activity; and chemokine activity. Acts upstream of or within negative regulation of myoblast differentiation. Predicted to be active in extracellular space. Is expressed in several str uctures, including alimentary system; brain; eye; genitourinary system; and limb. Orthologous to human CCL15 (C-C motif chemokine ligand 15) and CCL23 (C-C motif chemokine ligand 23). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 83463743 | 83469462 | Mouse | 178 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1323460 | CCRL2 | C-C motif chemokine receptor like 2 | This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008] | 3 | 46407259 | 46409523 | Human | 123 | old_gene_name , description | gene, protein-coding, REVIEWED [RefSeq] |
| 1308831 | Creb3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN DNA-templated transcription (ortholog); endoplasmic reticulum unfolded protein respons e (ortholog); induction of positive chemotaxis (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 62613652 | 62619019 | Rat | 153 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8992393 | Creb3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN DNA-templated transcription (ortholog); endoplasmic reticulum unfolded protein respons e (ortholog); induction of positive chemotaxis (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog) | NW_004955472 | 564227 | 568708 | Chinchilla | 65 | description | gene, protein-coding, MODEL [RefSeq] |
| 11757865 | CREB3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN induction of positive chemotaxis (ortholog); positive regulation of calcium ion transp ort (ortholog); positive regulation of cell migration (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | 9 | 35583351 | 35587870 | Bonobo | 68 | description | gene, protein-coding, MODEL [RefSeq] |
| 12428148 | CREB3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN induction of positive chemotaxis (ortholog); positive regulation of calcium ion transp ort (ortholog); positive regulation of cell migration (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | 11 | 52260340 | 52265085 | Dog | 68 | description | gene, protein-coding, MODEL [RefSeq] |
| 12621621 | Creb3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN induction of positive chemotaxis (ortholog); positive regulation of calcium ion transp ort (ortholog); positive regulation of cell migration (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | NW_004936524 | 3727104 | 3730962 | Squirrel | 68 | description | gene, protein-coding, MODEL [RefSeq] |
| 14004777 | CREB3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN induction of positive chemotaxis (ortholog); positive regulation of calcium ion transp ort (ortholog); positive regulation of cell migration (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | | | | Pig | 80 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18714507 | CREB3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN induction of positive chemotaxis (ortholog); positive regulation of calcium ion transp ort (ortholog); positive regulation of cell migration (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | | | | Green Monkey | 68 | description | gene, protein-coding, MODEL [RefSeq] |
| 18927368 | Creb3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); induction of positive chem otaxis (ortholog); negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog) | | | | Naked Mole-Rat | 69 | description | gene, protein-coding, MODEL [RefSeq] |
| 625851515 | Creb3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN DNA-templated transcription (ortholog); endoplasmic reticulum unfolded protein respons e (ortholog); induction of positive chemotaxis (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog) | | | | Black Rat | 65 | description | gene, protein-coding, MODEL [RefSeq] |
| 14026677 | LOC100516039 | C-C motif chemokine 23 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); INVOLVED IN cell chemotaxis (inferred); chemotaxis (inferred); immune response (inferred); ASSOCIATED WITH malignant mesothelioma (ortholog); FOUND IN extracellular region (inferred); ex tracellular space (inferred) | | | | Pig | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 11824196 | LOC100980531 | eotaxin | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); CCR1 chemokine receptor binding (inferred); CCR2 chemokine receptor binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cel l chemotaxis (inferred); chemokine-mediated signaling pathway (inferred); PARTICIPATES IN interleukin-4 signaling pathway; ASSOCIATED WITH allergic disease (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 17 | 22495737 | 22515144 | Bonobo | 74 | description | gene, protein-coding, MODEL [RefSeq] |
| 12018919 | LOC100991964 | C-C motif chemokine 4 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); CCR1 chemokine receptor binding (inferred); CCR5 chemokine receptor binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cel l chemotaxis (inferred); chemokine-mediated signaling pathway (inferred); FOUND IN extracellular region (inferred); extracellular space (inferred) | 17 | 19109618 | 19112193 | Bonobo | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 11862410 | LOC100992309 | C-C motif chemokine 3 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); CCR1 chemokine receptor binding (inferred); CCR5 chemokine receptor binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cal cium ion transport (inferred); calcium-mediated signaling (inferred); ASSOCIATED WITH Arsenic Poisoning (ortholog); skin disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); extracellular region (inferred) | 17 | 20704738 | 20706641 | Bonobo | 70 | description | gene, protein-coding, MODEL [RefSeq] |
| 18406404 | LOC103242711 | C-C motif chemokine 7 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR2 chemokine receptor binding (ortholog); chemokine activity (ortholog); INVOLVED IN cellular response to ethanol (ortholog); cytoskeleton organization (ortholog); eosinophil chemotaxi s (ortholog); ASSOCIATED WITH allergic conjunctivitis (ortholog); allergic disease (ortholog); asthma (ortholog); FOUND IN extracellular space (ortholog) | | | | Green Monkey | 56 | description | gene, protein-coding, MODEL [RefSeq] |
| 18730515 | LOC103242761 | C-C motif chemokine 23 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); chemokine activity (ortholog); ASSOCIATED WITH malignant mesothelioma (ortholog) | | | | Green Monkey | 4 | description | gene, protein-coding, MODEL [RefSeq] |
| 18385993 | LOC103242767 | C-C motif chemokine 3 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN astrocyte cell migration (ortholog); calcium ion transport (ortholog); calcium-mediated signa ling (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog) | | | | Green Monkey | 133 | description | gene, protein-coding, MODEL [RefSeq] |
| 32733379 | LOC117974322 | C-C motif chemokine 4 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); CCR1 chemokine receptor binding (inferred); CCR5 chemokine receptor binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); cel l chemotaxis (inferred); chemokine-mediated signaling pathway (inferred); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); Chronic Hepatitis C (ortholog); Colitis-Associated Neoplasms (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 17 | 20689341 | 20691921 | Bonobo | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 12276572 | LOC480600 | chemokine (C-C motif) ligand 3 | ENCODES a protein that exhibits CCR1 chemokine receptor binding (ortholog); CCR5 chemokine receptor binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN astrocyte cell migration (ortholog); calcium ion transport (ortholog); calcium-mediated signa ling (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Liver Failure (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog) | 9 | 37708561 | 37710209 | Dog | 128 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 16564408 | AC100793.2 | novel transcript, antisense to CCR10 | | | | | Human | | name | gene, lncrna |
| 620323 | Ackr2 | atypical chemokine receptor 2 | ENCODES a protein that exhibits C-C chemokine binding (ortholog); C-C chemokine receptor activity (ortholog); chemokine receptor activity (ortholog); INVOLVED IN signal transduction (ortholog); FOUND IN actin filament (ortholog); cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8 -Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; ammonium chloride | 8 | 130438703 | 130451106 | Rat | 102 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1310336 | Ccl19 | C-C motif chemokine ligand 19 | ENCODES a protein that exhibits CCR chemokine receptor binding (ortholog); CCR10 chemokine receptor binding (ortholog); CCR7 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); CC L19-activated CCR7 signaling pathway (ortholog); cell maturation (ortholog); PARTICIPATES IN chemokine mediated signaling pathway; ASSOCIATED WITH allergic contact dermatitis (ortholog); allergic disease (ortholog); aspergillosis (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-estradiol 3-benzoate | 5 | 61759220 | 61761164 | Rat | 181 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8854801 | Ccl19 | C-C motif chemokine ligand 19 | ENCODES a protein that exhibits CCR chemokine receptor binding (ortholog); CCR10 chemokine receptor binding (ortholog); CCR7 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); CC L19-activated CCR7 signaling pathway (ortholog); cell maturation (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); allergic disease (ortholog); aspergillosis (ortholog); FOUND IN external side of plasma membrane (ortholog) | NW_004955472 | 1444598 | 1446488 | Chinchilla | 58 | description | gene, protein-coding, MODEL [RefSeq] |
| 626125936 | Ccl19 | C-C motif chemokine ligand 19 | ENCODES a protein that exhibits CCR chemokine receptor binding (ortholog); CCR10 chemokine receptor binding (ortholog); CCR7 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); CC L19-activated CCR7 signaling pathway (ortholog); cell maturation (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); allergic disease (ortholog); aspergillosis (ortholog); FOUND IN external side of plasma membrane (ortholog) | | | | Black Rat | 58 | description | gene, protein-coding, MODEL [RefSeq] |
| 28912684 | Ccl19-ps1 | C-C motif chemokine ligand 19, pseudogene 1 | Predicted to enable CCR10 chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to virus; establishment of T cell polarity; and positive regulation of intracellular signal transduct ion. [provided by Alliance of Genome Resources, Apr 2025] | 4 | 41921279 | 41923225 | Mouse | | description | gene, pseudo, VALIDATED [RefSeq] |
| 1616797 | Ccl19-ps3 | C-C motif chemokine ligand 19, pseudogene 3 | Predicted to enable CCR10 chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to virus; establishment of T cell polarity; and positive regulation of intracellular signal transduct ion. [provided by Alliance of Genome Resources, Apr 2025] | 4 | 42132521 | 42134376 | Mouse | 1 | description | gene, pseudo, INFERRED [RefSeq] |
| 2302347 | Ccl19-ps4 | C-C motif chemokine ligand 19, pseudogene 4 | Predicted to enable CCR10 chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to virus; establishment of T cell polarity; and positive regulation of intracellular signal transduct ion. [provided by Alliance of Genome Resources, Apr 2025] | 4 | 42629753 | 42631714 | Mouse | | description | gene, pseudo, MODEL [RefSeq] |
| 2295514 | Ccl19-ps5 | C-C motif chemokine ligand 19, pseudogene 5 | Predicted to enable CCR10 chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to virus; establishment of T cell polarity; and positive regulation of intracellular signal transduct ion. [provided by Alliance of Genome Resources, Apr 2025] | 4 | 41791784 | 41793745 | Mouse | | description | gene, pseudo, MODEL [RefSeq] |
| 7178944 | Ccl19-ps6 | C-C motif chemokine ligand 19, pseudogene 6 | Predicted to enable CCR10 chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to virus; establishment of T cell polarity; and positive regulation of intracellular signal transduct ion. [provided by Alliance of Genome Resources, Apr 2025] | 4 | 42070757 | 42072794 | Mouse | | description | gene, pseudo, VALIDATED [RefSeq] |
| 1305530 | Ccl25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cell chemotaxis (or tholog); chemotaxis (ortholog); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Jaundice; pleurisy (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole | 12 | 7505231 | 7514402 | Rat | 95 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9007207 | Ccl25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cell chemotaxis (or tholog); chemotaxis (ortholog); ASSOCIATED WITH Jaundice (ortholog); pleurisy (ortholog) | NW_004955563 | 1249098 | 1255469 | Chinchilla | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 11854722 | CCL25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR chemokine receptor binding (inferred); CCR10 chemokine receptor binding (inferred); chemokine activity (inferred); INVOLVED IN chemotaxis (ortholog); leukocyte migration (ortholog); ASSOCIATED WITH Jaundice (ortholog); pleuris y (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 19 | 7307109 | 7363983 | Bonobo | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 12270307 | CCL25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine receptor binding (ortholog); INVOLVED IN chemotaxis (ortholog); G protein-coupled receptor signaling pathway (ortholog); leukocyte migration (ortholog); ASSOCIATED WITH Jaundi ce (ortholog); pleurisy (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 20 | 52689674 | 52722291 | Dog | 29 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12604138 | Ccl25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cell chemotaxis (or tholog); chemotaxis (ortholog); ASSOCIATED WITH Jaundice (ortholog); pleurisy (ortholog) | NW_004936588 | 4973476 | 4998365 | Squirrel | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 18444979 | CCL25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cell chemotaxis (or tholog); chemotaxis (ortholog); ASSOCIATED WITH Jaundice (ortholog); pleurisy (ortholog) | | | | Green Monkey | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 18930346 | Ccl25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); chemotaxis (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Jaundice (ortholog); pleurisy (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Naked Mole-Rat | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 625921767 | Ccl25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cell chemotaxis (or tholog); chemotaxis (ortholog); ASSOCIATED WITH Jaundice (ortholog); pleurisy (ortholog) | | | | Black Rat | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 1312228 | CCL27 | C-C motif chemokine ligand 27 | This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemot actic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014] | 9 | 34661890 | 34662657 | Human | 108 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1349737 | CCL28 | C-C motif chemokine ligand 28 | This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotac tic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2014] | 5 | 43356975 | 43412391 | Human | 116 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1564256 | Cxcl13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); CXCR3 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); B cell chemot axis (ortholog); B cell chemotaxis across high endothelial venule (ortholog); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17beta-estradiol | 14 | 13912858 | 13917920 | Rat | 200 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8745040 | Cxcl13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); CXCR3 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); B cell chemot axis (ortholog); B cell chemotaxis across high endothelial venule (ortholog); ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog) | NW_004955433 | 2123190 | 2129119 | Chinchilla | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 11848958 | CXCL13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (inferred); chemokine activity (inferred); CXCR3 chemokine receptor binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); B cell chemot axis across high endothelial venule (ortholog); chemokine-mediated signaling pathway (ortholog); ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 4 | 46583759 | 46589865 | Bonobo | 40 | description | gene, protein-coding, MODEL [RefSeq] |
| 12191236 | CXCL13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (inferred); chemokine activity (inferred); CXCR3 chemokine receptor binding (inferred); INVOLVED IN B cell chemotaxis across high endothelial venule (ortholog); chemokine-mediated signaling pathway (ortholog); lymph node development (ortholog); ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 32 | 2047277 | 2053277 | Dog | 47 | description | gene, protein-coding, MODEL [RefSeq] |
| 12669880 | Cxcl13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (inferred); chemokine activity (inferred); CXCR3 chemokine receptor binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); B cell chemot axis across high endothelial venule (ortholog); chemokine-mediated signaling pathway (ortholog); ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | NW_004936676 | 1309625 | 1314532 | Squirrel | 39 | description | gene, protein-coding, MODEL [RefSeq] |
| 13865318 | CXCL13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); CXCR3 chemokine receptor binding (ortholog); CXCR5 chemokine receptor binding (ortholog); INVOLVED IN B cell chemotaxis (ortholog); B cell chemotaxis across high endothelial venule (ort holog); cell surface receptor signaling pathway (ortholog); ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH deoxynivalenol; zearalenone | | | | Pig | 51 | description | gene, protein-coding, MODEL [RefSeq] |
| 18603681 | CXCL13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (inferred); chemokine activity (inferred); CXCR3 chemokine receptor binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); lymph node de velopment (ortholog); ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Green Monkey | 42 | description | gene, protein-coding, MODEL [RefSeq] |
| 18930906 | Cxcl13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); CXCR3 chemokine receptor binding (ortholog); CXCR5 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); B cell chemotaxis (ortholog); B cell chemotaxis across high endothelial venule (ortholog); ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Naked Mole-Rat | 40 | description | gene, protein-coding, MODEL [RefSeq] |
| 626004631 | Cxcl13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); CXCR3 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); B cell chemot axis (ortholog); B cell chemotaxis across high endothelial venule (ortholog); ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog) | | | | Black Rat | 34 | description | gene, protein-coding, MODEL [RefSeq] |