Ccl25 (C-C motif chemokine ligand 25)

Gene: Ccl25 (C-C motif chemokine ligand 25) Ictidomys tridecemlineatus

Analyze

Symbol:

Ccl25

Name:

C-C motif chemokine ligand 25

RGD ID:

12604138

Description:

ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cell chemotaxis (ortholog); chemotaxis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); familial hemophagocytic lymphohistiocytosis 5 (ortholog); genetic disease (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

C-C motif chemokine 25; LOC106145108; uncharacterized LOC106145108

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	212,836,389 - 212,861,308 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936588	4,973,476 - 4,998,365 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

familial hemophagocytic lymphohistiocytosis 5 (ISO)

genetic disease (ISO)

Jaundice (ISO)

mucolipidosis type IV (ISO)

pleurisy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antimicrobial humoral immune response mediated by antimicrobial peptide (ISO)

cell chemotaxis (ISO)

chemotaxis (ISO)

G protein-coupled receptor signaling pathway (ISO)

leukocyte migration (ISO)

lymphoid lineage cell migration (ISO)

negative regulation of leukocyte tethering or rolling (ISO)

positive regulation of cell-matrix adhesion (ISO)

Molecular Function

CCR10 chemokine receptor binding (ISO)

chemokine activity (ISO)

chemokine receptor binding (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Ccl25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	212,836,389 - 212,861,308 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936588	4,973,476 - 4,998,365 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCL25
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	8,052,341 - 8,062,650 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	8,052,318 - 8,062,660 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	8,117,225 - 8,127,534 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	8,023,934 - 8,033,547 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	8,023,933 - 8,033,534	NCBI
Celera	19	7,989,167 - 7,998,769 (+)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	7,788,562 - 7,797,973 (+)	NCBI		HuRef
CHM1_1	19	8,117,421 - 8,127,895 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	8,053,362 - 8,063,660 (+)	NCBI		T2T-CHM13v2.0

Ccl25
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	4,375,207 - 4,410,020 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	4,375,210 - 4,410,020 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	4,325,205 - 4,360,020 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	4,325,210 - 4,360,020 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	4,325,210 - 4,360,020 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	4,349,615 - 4,360,020 (+)	NCBI		MGSCv36	mm8
Celera	8	4,525,811 - 4,560,621 (+)	NCBI		Celera
Cytogenetic Map	8	A1.1	NCBI
cM Map	8	2.01	NCBI

Ccl25
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	7,505,231 - 7,514,402 (+)	NCBI		GRCr8
mRatBN7.2	12	2,707,398 - 2,716,571 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	2,707,398 - 2,716,554 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	3,355,480 - 3,364,652 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	3,979,068 - 3,988,240 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	2,742,050 - 2,751,328 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	2,429,492 - 2,438,928 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	2,429,509 - 2,438,817 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	4,583,182 - 4,592,166 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	1,427,242 - 1,436,436 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	1,427,553 - 1,439,348 (-)	NCBI
Celera	12	4,522,920 - 4,532,044 (+)	NCBI		Celera
Cytogenetic Map	12	p12	NCBI

Ccl25
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955563	1,249,098 - 1,255,469 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCL25
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	12,734,718 - 12,745,594 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	11,851,953 - 11,862,815 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	7,307,109 - 7,363,983 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	8,208,273 - 8,217,780 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	8,208,273 - 8,217,780 (+)	Ensembl	panpan1.1		panPan2

CCL25
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	52,689,674 - 52,722,291 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	52,712,979 - 52,722,018 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	52,520,955 - 52,523,887 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	53,217,788 - 53,250,217 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	53,217,446 - 53,250,227 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	52,450,071 - 52,453,004 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	52,894,798 - 52,897,724 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	53,126,468 - 53,129,402 (+)	NCBI		UU_Cfam_GSD_1.0

CCL25
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	71,175,075 - 71,206,950 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	71,175,066 - 71,206,950 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	71,575,448 - 71,607,365 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCL25
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	7,496,463 - 7,504,637 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666081	306,230 - 353,525 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccl25
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624828	975,656 - 981,610 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021730965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040290528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040290529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001229977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002484725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005736015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005736017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005736018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005736019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005736020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021730965 ⟹ XP_021586640

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,836,389 - 212,861,308 (-)	NCBI
SpeTri2.0	NW_004936588	4,973,476 - 4,998,365 (+)	NCBI

Sequence:

show sequence

AATTGAACTGACTGCATTTCAGGGACTCATCAGTCATCTATCACCTGTCACCACCTGTGCAGTG
GAGATGGGGAGGCAGAAGAGAAAGCAAGTGGATCCCACCTCAAGTGATGAAAAGGGATCACATC
CAGGATCCCATGTTACATGTAATTTAATTGTCCTATCTAATCTCTTGCCTGTGGAAGATTCAGA
TTCTCCTTGTTTTTGATGGCCTTGACAGTTTTGAGGAGTGCTGCTCAGGAAGGGAACAGAAGTG
AACATGGAATTCAGCCTGAGAAGGAGGGAGGCACAGAGGCTGTGTGCACGAGGCAGGTGGAGTG
TCAGAGCACAGGCCACTCTGTCTATCCTTGAAGTGCCCAGAGAGGAGGTCCTGCCTGCACCATG
AACCCTTGGATCCTTGCCAGCCTGGCAGCCTGCTTTTTGGGGGCCTGGGTCCCTCCCATCCACA
CCCAAGGGTCCTTTGAGGACTGCTGTCTGGGTTACTACCCTAAACCCAAGTTGGCTGTGCTCCG
TCGCGCCAGCTTTTACCGGATCCAGGAGGTGAGCGGCAGCTGCAACCTGTTTGCCATCGTATTC
TACTTCCGCCAACCAGGTAAAATGGTGTGTGGGAACCCAAGGGACATCAGGGTACGGAAGGCAA
TGAGATTGGTCTCCCAGAGGTCTGACAACCGGCTAACCATCCAAGACTCTCAGGCTGGGAGGAA
GAAATCTCGGCGACCATCGTCCAGGCCAAAGTATCTCAGCAGTAACAATAGCAGCAGCAGCAGC
AGCAGCAGCAGCAGCAGCAAAAGAAATGCTTCCCTAATCTAATCCAGCCCCCGAGGCCACTGCA
GTCCCACCTCTAATCCCTCCTGCAGGGCCATGAGCCTGCACATCTCCAGGATCCAACAGCAGGA
CAGAGGCCAGAGGGATCTTGCTCCACCAGCGGTCACCCTGCAGCCCCAGCTGCCTCTGCCCCTC
GTCCTTCAGCCCCAATCCTAGCCCCTGTGCCCGGATTGGTTTGCTCCTTTCTATTCCTACCACC
TCCTGCCCCTTGGGCAGCTGGGAAGAGGGACAGCTCCTTTCTACTCTGGGATAAGTACCAACCT
TGGGCAAAGGTTCTTGGAGACAAGATTCTTTTGGACTATGTCACCCACCTGCAGCTTCTTGCCA
TTCACCCCAGGCCACCTACTGTGTCCCTCCAGGTCCTTGCAAAGTTTTGATTGGTACAAAAAAC
ATCCTCCCAGTCTAAGCTTT

hide sequence

RefSeq Acc Id:

XM_040290528 ⟹ XP_040146462

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,836,390 - 212,841,167 (-)	NCBI

RefSeq Acc Id:

XM_040290529 ⟹ XP_040146463

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,836,389 - 212,842,133 (-)	NCBI

RefSeq Acc Id:

XR_001229977

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,855,038 - 212,861,308 (-)	NCBI
SpeTri2.0	NW_004936588	4,973,476 - 4,979,745 (+)	NCBI

Sequence:

show sequence

AATTGAACTGACTGCATTTCAGGGACTCATCAGTCATCTATCACCTGTCACCACCTGTGCAGTG
GAGATGGGGAGGCAGAAGAGAAAGCAAGTGGATCCCACCTCAAGTGATGAAAAGGGATCACATC
CAGGATCCCATGTTACATGTAATTTAATTGTCCTATCTAATCTCTTGCCTGTGGAAGATTCAGA
TTCTCCTTGTTTTTGATGGCCTTGACAGTTTTGAGGAGTGCTGCTCAGGAAGGGAACAGAAGTG
AACATGGAATTCAGCCTGAGAAGGAGGGAGGCACAGAGGCTGTGTGCACGAGGCAGGTGGAGTG
TCAGAGCACAGGCTCCTTTGTATTTTCAAGTGAAAATTCAGTGGTTTCTAATGGAGTCGCAAAG
GAATGCGACTGCCAGCACTCTCGTTCCAGAACATTCTCATCTCTCCAGAAAGAAACCCTGTGTC
CCTTAGCTGTCATTCCCTGTTCTACCCCCCACAGCAACTAGCAACAGTTAATCTGCTCTCTGAC
TCTCTGGATTGCCTCTTCTAGATACTTTGTATAAATGGAGTTTTATAGTA

hide sequence

RefSeq Acc Id:

XR_002484725

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,855,038 - 212,861,308 (-)	NCBI
SpeTri2.0	NW_004936588	4,973,476 - 4,978,869 (+)	NCBI

Sequence:

show sequence

AATTGAACTGACTGCATTTCAGGGACTCATCAGTCATCTATCACCTGTCACCACCTGTGCAGTG
GAGATGGGGAGGCAGAAGAGAAAGCAAGTGGATCCCACCTCAAGTGATGAAAAGGGATCACATC
CAGGATCCCATGTTACATGTAATTTAATTGTCCTATCTAATCTCTTGCCTGTGGAAGATTCAGA
TTCTCCTTGTTTTTGATGGCCTTGACAGTTTTGAGGAGTGCTGCTCAGGAAGGGAACAGAAGTG
AACATGGAATTCAGCCTGAGAAGGAGGGAGGCACAGAGGCTGTGTGCACGAGGCAGGTGGAGTG
TCAGAGCACAGGTTGACATCTAGGAAGGCCACACCCAAA

hide sequence

RefSeq Acc Id:

XR_005736015

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,855,038 - 212,861,308 (-)	NCBI

RefSeq Acc Id:

XR_005736017

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,838,100 - 212,861,308 (-)	NCBI

RefSeq Acc Id:

XR_005736018

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,849,269 - 212,861,308 (-)	NCBI

RefSeq Acc Id:

XR_005736019

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,837,994 - 212,861,308 (-)	NCBI

RefSeq Acc Id:

XR_005736020

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	212,848,014 - 212,861,308 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_021586640	(Get FASTA)	NCBI Sequence Viewer
	XP_040146462	(Get FASTA)	NCBI Sequence Viewer
	XP_040146463	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_021586640 ⟸ XM_021730965
- Sequence:	show sequence MNPWILASLAACFLGAWVPPIHTQGSFEDCCLGYYPKPKLAVLRRASFYRIQEVSGSCNLFAIV FYFRQPGKMVCGNPRDIRVRKAMRLVSQRSDNRLTIQDSQAGRKKSRRPSSRPKYLSSNNSSSS SSSSSSSKRNASLI hide sequence

RefSeq Acc Id:

XP_040146463 ⟸ XM_040290529

RefSeq Acc Id:

XP_040146462 ⟸ XM_040290528

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Ccl25	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-07-14	Ccl25	C-C motif chemokine ligand 25	LOC106145108	uncharacterized LOC106145108	Data merged from RGD:12483685	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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