chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway
DNA alkylation repair
DNA ligation involved in DNA repair +
DNA replication proofreading
DNA synthesis involved in DNA repair +
double-strand break repair +
interstrand cross-link repair +
mismatch repair +
mitochondrial DNA repair
negative regulation of DNA repair +
non-photoreactive DNA repair
nucleotide-excision repair +
A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).