Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:double-strand break repair
go back to main search page
Accession:GO:0006302 term browser browse the term
Definition:The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
Comment:Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable (PMID:22214610). To annotate gene products involved in mitochondrial double-strand break repair, please use GO:0097551 'mitochondrial double-strand break repair'.


show annotations for term's descendants           Sort by:
 
double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:17525340), (PMID:17643121), (PMID:19261748)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000024 GO_REF:0000107 NCBI chr14:8,796,281...8,810,625
Ensembl chr14:8,796,266...8,810,622
JBrowse link
G Actr5 actin related protein 5 involved_in ISO (PMID:19014934) RGD PMID:19014934 NCBI chr 3:147,282,461...147,296,110
Ensembl chr 3:147,282,624...147,296,110
JBrowse link
G Actr8 actin related protein 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:5,164,131...5,186,353
Ensembl chr16:5,164,129...5,178,577
JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 involved_in IMP
ISO
PMID:19282473
(MGI:3698695|PMID:17121854)
RGD PMID:17121854 PMID:19282473 MGI:3698695, RGD:8553580 NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627
JBrowse link
G Aplf aprataxin and PNKP like factor involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17396150)
MGI:4128102 (MGI:4887518|PMID:21211721)
PMID:21873635
RGD PMID:17396150 PMID:21211721 PMID:21873635 MGI:4887518, RGD:13792537 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
JBrowse link
G Aptx aprataxin involved_in IBA
ISO
PMID:21873635
(PMID:17519253)
RGD PMID:17519253 PMID:21873635 RGD:13792537 NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855
JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISO
ISS
(PMID:19261746), (PMID:19261748), (PMID:19261749)
GO_REF:0000024
RGD
UniProt
PMID:19261746 PMID:19261748 PMID:19261749 GO_REF:0000024 NCBI chr16:18,068,830...18,074,938
Ensembl chr16:18,068,884...18,074,923
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19261748)
UniProt
RGD
PMID:19261748 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748), (PMID:22186889)
(MGI:5545964|PMID:22186889)
RGD PMID:17525340 PMID:17643121 PMID:19261748 PMID:22186889 MGI:5545964 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
ISO (PMID:16845393)
MGI:2156556|MGI:2176173|MGI:2177226 (MGI:1100157|PMID:9398843), (MGI:3714678|PMID:17476307)
RGD PMID:9398843 PMID:16845393 PMID:17476307 MGI:1100157 MGI:3714678 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 involved_in ISO
ISS
IBA
(PMID:17525341), (PMID:19261746), (PMID:19261748)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:17525341 PMID:19261746 PMID:19261748 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
JBrowse link
G Cdca5 cell division cycle associated 5 involved_in ISO
IBA
(PMID:17349791)
PMID:21873635
RGD PMID:17349791 PMID:21873635 RGD:13792537 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Chek2 checkpoint kinase 2 involved_in ISO (PMID:18317453) RGD PMID:18317453 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Dclre1c DNA cross-link repair 1C acts_upstream_of_or_within ISO (MGI:3514096|PMID:12615897) RGD PMID:12615897 MGI:3514096 NCBI chr17:74,775,828...74,810,089
Ensembl chr17:74,776,935...74,809,186
JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:18710941)
UniProt
RGD
PMID:18710941 GO_REF:0000024 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:23230272) RGD PMID:23230272 NCBI chr11:64,814,926...64,824,538
Ensembl chr11:64,814,926...64,824,538
JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:79,586,736...79,595,515
Ensembl chr10:79,586,729...79,595,435
JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:13,913,216...13,915,991
Ensembl chr10:13,913,221...13,915,968
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit NOT|acts_upstream_of_or_within ISO MGI:2183944 (MGI:2153690|PMID:11707424)
MGI:2158940|MGI:2183944|MGI:3617449 (MGI:3047512|PMID:15199134), (MGI:3770581|PMID:17912366)
RGD PMID:11707424 PMID:15199134 PMID:17912366 MGI:2153690 MGI:3047512 MGI:3770581 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 acts_upstream_of_or_within ISO MGI:5308063 (MGI:5493398|PMID:22614755) RGD PMID:22614755 MGI:5493398 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:26807646) RGD PMID:26807646 NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (PMID:19234442) RGD PMID:19234442 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in ISO (PMID:19234442) RGD PMID:19234442 NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518
JBrowse link
G Ggn gametogenetin acts_upstream_of_or_within ISO MGI:5503309 (MGI:5502508|PMID:23451117) RGD PMID:23451117 MGI:5502508 NCBI chr 1:84,470,488...84,474,120
Ensembl chr 1:84,470,508...84,474,114
JBrowse link
G Hpf1 histone PARylation factor 1 involved_in ISO (PMID:32939087) RGD PMID:32939087 NCBI chr16:29,203,749...29,219,651
Ensembl chr16:29,183,256...29,219,716
JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20687897) RGD PMID:20687897 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911
JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO
IEA
(PMID:10966108)
GO_REF:0000107
RGD
Ensembl
PMID:10966108 GO_REF:0000107 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
G Lig3 DNA ligase 3 involved_in ISO (PMID:19589734) RGD PMID:19589734 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
G Lig4 DNA ligase 4 involved_in
acts_upstream_of_or_within
ISO (PMID:19589734), (PMID:9242410)
MGI:104517|MGI:1857732|MGI:3714783|MGI:894697 (MGI:2445902|PMID:12531011), (MGI:3043875|PMID:15175260), (MGI:3715270|PMID:17554302)
RGD PMID:9242410 PMID:12531011 PMID:15175260 PMID:17554302 PMID:19589734 MGI:2445902 MGI:3043875 MGI:3715270 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G LOC103689943 meiosis arrest female protein 1-like acts_upstream_of_or_within ISO MGI:3512917 (MGI:5461283|PMID:23090997) RGD PMID:23090997 MGI:5461283
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO
ISS
(PMID:15988022)
GO_REF:0000024
RGD
UniProt
PMID:15988022 GO_REF:0000024 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Marf1 meiosis regulator and mRNA stability factor 1 acts_upstream_of_or_within ISO MGI:3512917 (MGI:5461283|PMID:23090997) RGD PMID:23090997 MGI:5461283 NCBI chr10:888,053...932,760
Ensembl chr10:888,076...932,753
JBrowse link
G Meioc meiosis specific with coiled-coil domain involved_in ISO (MGI:5770021|PMID:26742488) RGD PMID:26742488 MGI:5770021 NCBI chr10:87,628,807...87,646,485
Ensembl chr10:87,628,875...87,646,752
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease acts_upstream_of_or_within ISO MGI:3027036 (MGI:3707920|PMID:17291760) RGD PMID:17291760 MGI:3707920 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1858055 (MGI:3770581|PMID:17912366)
Ensembl
RGD
PMID:17912366 GO_REF:0000107 MGI:3770581 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Mta1 metastasis associated 1 involved_in IEA
ISO
ISS
IBA
GO_REF:0000107
(MGI:4366101|PMID:19805145)
GO_REF:0000024
(PMID:19805145)
PMID:21873635
Ensembl
RGD
UniProt
PMID:19805145 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4366101, RGD:13792537 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
JBrowse link
G Nbn nibrin involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:9590181)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:9590181 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in
acts_upstream_of_or_within
ISO
IBA
ISS
(PMID:23230272)
PMID:21873635
MGI:1891258 (MGI:4947917|PMID:21270334)
GO_REF:0000024
RGD
UniProt
PMID:21270334 PMID:23230272 PMID:21873635 GO_REF:0000024 MGI:4947917, RGD:13792537 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 involved_in ISO
IBA
(PMID:32939087)
PMID:21873635
RGD PMID:32939087 PMID:21873635 RGD:13792537 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338
JBrowse link
G Parp3 poly (ADP-ribose) polymerase family, member 3 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1340806 (MGI:4947917|PMID:21270334)
PMID:21873635
(PMID:21211721), (PMID:21270334)
RGD PMID:21211721 PMID:21270334 PMID:21873635 MGI:4947917, RGD:13792537 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO (PMID:23230272) RGD PMID:23230272 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455
JBrowse link
G Poln DNA polymerase nu involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:76,579,983...76,752,460 JBrowse link
G Polq DNA polymerase theta involved_in ISO
IBA
(PMID:22135286)
PMID:21873635
RGD PMID:22135286 PMID:21873635 RGD:13792537 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:18710952)
MGI:1857113|MGI:2667593 (MGI:2155497|PMID:11751629), (MGI:2450507|PMID:12604618)
PMID:21873635
RGD PMID:11751629 PMID:12604618 PMID:18710952 PMID:21873635 MGI:2155497 MGI:2450507, RGD:13792537 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 acts_upstream_of_or_within ISO MGI:5292341 (MGI:5288570|PMID:21743440) RGD PMID:21743440 MGI:5288570 NCBI chr 3:140,160,128...140,188,324
Ensembl chr 3:140,160,118...140,188,298
JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in TAS
IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:9590181)
UniProt
RGD
PMID:9590181 PMID:10908350 PMID:21873635 GO_REF:0000024, RGD:68816, RGD:13792537 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Rad54l RAD54 like acts_upstream_of_or_within ISO MGI:1335098 (MGI:3043875|PMID:15175260) RGD PMID:15175260 MGI:3043875 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Rnf168 ring finger protein 168 involved_in IEA
ISS
ISO
GO_REF:0000104
GO_REF:0000024
(PMID:19203578), (PMID:19203579), (PMID:22980979)
UniProt
RGD
PMID:19203578 PMID:19203579 PMID:22980979 GO_REF:0000024 GO_REF:0000104 NCBI chr11:68,486,313...68,508,296
Ensembl chr11:68,486,321...68,508,277
JBrowse link
G Rnf8 ring finger protein 8 involved_in ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000104
(PMID:18001824), (PMID:18001825), (PMID:22980979)
PMID:21873635
UniProt
RGD
PMID:18001824 PMID:18001825 PMID:22980979 PMID:21873635 GO_REF:0000024 GO_REF:0000104, RGD:13792537 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491
JBrowse link
G Setx senataxin involved_in ISO (PMID:17562789) RGD PMID:17562789 NCBI chr 3:12,428,091...12,480,801
Ensembl chr 3:12,427,635...12,480,803
JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 involved_in ISO
IEA
IBA
(PMID:12023295)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:12023295 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 6:119,163,192...119,231,029
Ensembl chr 6:119,163,166...119,231,021
JBrowse link
G Tdp2 tyrosyl-DNA phosphodiesterase 2 involved_in IBA
IEA
ISS
ISO
PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:19794497), (PMID:21030584)
Ensembl
UniProt
RGD
PMID:19794497 PMID:21030584 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr17:40,228,943...40,240,337
Ensembl chr17:40,228,947...40,240,313
JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 involved_in ISO (PMID:25749521) RGD PMID:25749521 NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1857989 (MGI:3770581|PMID:17912366) RGD PMID:17912366 MGI:3770581 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4821667|PMID:20711356)
MGI:3719273 (MGI:3719060|PMID:17696610)
UniProt
RGD
PMID:17696610 PMID:20711356 GO_REF:0000024 MGI:3719060 MGI:4821667 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074
JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in ISS
IBA
ISO
IEA
GO_REF:0000024
PMID:21873635
(PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 More... GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr17:9,523,793...9,592,810
Ensembl chr17:9,527,794...9,592,799
JBrowse link
G Vcp valosin-containing protein involved_in ISS
ISO
GO_REF:0000024
(PMID:10855792), (PMID:22120668)
UniProt
RGD
PMID:10855792 PMID:22120668 GO_REF:0000024 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link
G Wrn WRN RecQ like helicase involved_in ISO (PMID:21639834) RGD PMID:21639834 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in
acts_upstream_of_or_within
ISO (PMID:9242410)
MGI:1926771 (MGI:1913213|PMID:9875844), (MGI:2155497|PMID:11751629)
RGD PMID:9242410 PMID:9875844 PMID:11751629 MGI:1913213 MGI:2155497 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 acts_upstream_of_or_within
involved_in
NAS
ISO
MGI:1335098|MGI:2179987 (MGI:2445902|PMID:12531011)
(PMID:19581589)
RGD PMID:12531011 PMID:19581589 PMID:11966321 MGI:2445902, RGD:727219 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 acts_upstream_of_or_within TAS
ISO
MGI:2179954 (MGI:2155497|PMID:11751629) RGD PMID:11751629 PMID:11966321 MGI:2155497, RGD:727219 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
JBrowse link
DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in ISO (PMID:21325134) RGD PMID:21325134 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21325134)
UniProt
Ensembl
RGD
PMID:21325134 GO_REF:0000024 GO_REF:0000107 NCBI chr20:25,661,652...25,690,598 JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:26807646) RGD PMID:26807646 NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442
JBrowse link
G Setmar SET domain and mariner transposase fusion gene involved_in ISO (PMID:21491884) RGD PMID:21491884 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197
JBrowse link
G Slc25a16 solute carrier family 25 member 16 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,661,158...25,717,558 JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` involved_in ISO
ISS
(PMID:22960744)
GO_REF:0000024
RGD
UniProt
PMID:22960744 GO_REF:0000024 NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:17349954) RGD PMID:17349954 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 involved_in ISO (PMID:17349954) RGD PMID:17349954 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369
JBrowse link
DNA double-strand break processing involved in repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07031480.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Rad52 RAD52 homolog, DNA repair protein involved_in
acts_upstream_of_or_within
ISO (MGI:5619739|PMID:22912580)
(PMID:19506022)
RGD PMID:19506022 PMID:22912580 MGI:5619739 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000002
(PMID:18716619), (PMID:19202191)
InterPro
RGD
PMID:18716619 PMID:19202191 PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G RGD1565844 similar to RIKEN cDNA 1700045I19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:30,739,541...30,740,614
Ensembl chr  X:30,739,413...30,740,613
JBrowse link
G Rnf138 ring finger protein 138 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:26502057)
UniProt
RGD
PMID:26502057 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:12,291,557...12,315,931 JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:19595721) RGD PMID:19595721 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775
JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:19595721) RGD PMID:19595721 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295
JBrowse link
DNA recombinase assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmc1 DNA meiotic recombinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:111,124,888...111,167,465
Ensembl chr 7:111,124,888...111,167,952
JBrowse link
G Rad51 RAD51 recombinase involved_in ISO
IBA
(PMID:26681308)
PMID:21873635
RGD PMID:26681308 PMID:21873635 RGD:13792537 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad52 RAD52 homolog, DNA repair protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
double-strand break repair involved in meiotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brip1 BRCA1 interacting helicase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:4129733 (MGI:5700253|PMID:26490168)
RGD PMID:26490168 PMID:21873635 MGI:5700253, RGD:13792537 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Brme1 break repair meiotic recombinase recruitment factor 1 involved_in ISO (MGI:6443349|PMID:32463460), (MGI:6447091|PMID:32345962), (MGI:6448646|PMID:32460033) RGD PMID:32345962 PMID:32460033 PMID:32463460 MGI:6443349 MGI:6447091 MGI:6448646 NCBI chr19:23,990,049...24,011,774
Ensembl chr19:23,990,045...24,011,850
JBrowse link
G Fancd2 FA complementation group D2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein involved_in ISO (MGI:6283956|PMID:30760716), (MGI:6443349|PMID:32463460), (MGI:6447091|PMID:32345962), (MGI:6456264|PMID:31242413) RGD PMID:30760716 PMID:31242413 PMID:32345962 PMID:32463460 MGI:6283956 MGI:6443349 MGI:6447091 MGI:6456264 NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242
JBrowse link
G Mcmdc2 minichromosome maintenance domain containing 2 acts_upstream_of_or_within ISO MGI:1349669|MGI:2178050|MGI:5511194 (MGI:5805564|PMID:27760146) RGD PMID:27760146 MGI:5805564 NCBI chr 5:9,291,967...9,337,526
Ensembl chr 5:9,298,101...9,338,300
JBrowse link
G Morc2b microrchidia 2B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 7:12,314,341...12,318,421
Ensembl chr 7:12,314,349...12,318,421
JBrowse link
G Prdm9 PR/SET domain 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:6102131|PMID:25894966), (MGI:6114980|PMID:29478809)
UniProt
RGD
PMID:25894966 PMID:29478809 GO_REF:0000024 MGI:6102131 MGI:6114980 NCBI chr 1:56,505,579...56,525,726
Ensembl chr 1:56,505,579...56,525,652
JBrowse link
G Spo11 SPO11, initiator of meiotic double stranded breaks acts_upstream_of_or_within ISO MGI:3045334 (MGI:5805564|PMID:27760146) RGD PMID:27760146 MGI:5805564 NCBI chr 3:161,755,299...161,770,930
Ensembl chr 3:161,757,519...161,770,925
JBrowse link
double-strand break repair via alternative nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (MGI:6393148|PMID:31806351) RGD PMID:31806351 MGI:6393148 NCBI chr 4:120,392,812...120,415,616 JBrowse link
G Lig3 DNA ligase 3 involved_in ISO
IBA
UniProtKB:P13010 (PMID:24837021)
(MGI:5014103|PMID:21655080)
PMID:21873635
RGD PMID:21655080 PMID:24837021 PMID:21873635 MGI:5014103, RGD:13792537 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
G Polq DNA polymerase theta involved_in ISO
IBA
(PMID:25643323)
PMID:21873635
(MGI:5621198|PMID:25642960)
RGD PMID:25642960 PMID:25643323 PMID:21873635 MGI:5621198, RGD:13792537 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
JBrowse link
double-strand break repair via break-induced replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc45 cell division cycle 45 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdc7 cell division cycle 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Gins2 GINS complex subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
JBrowse link
G Gins4 GINS complex subunit 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Mcmdc2 minichromosome maintenance domain containing 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:9,291,967...9,337,526
Ensembl chr 5:9,298,101...9,338,300
JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:202,790,295...202,796,008
Ensembl chr 1:202,790,466...202,795,843
JBrowse link
double-strand break repair via classical nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:29545921) RGD PMID:29545921 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in ISO (PMID:29545921) RGD PMID:29545921 NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859
JBrowse link
G Lig4 DNA ligase 4 involved_in ISO (PMID:24837021) RGD PMID:24837021 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Uvrag UV radiation resistance associated involved_in ISO (PMID:22542840) RGD PMID:22542840 NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:24095731) RGD PMID:24095731 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5702356|PMID:26446488)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:26446488 GO_REF:0000024 GO_REF:0000107 MGI:5702356 NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539
JBrowse link
double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07031480.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07067300.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AC095390.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AC117889.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AC134087.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Ap5s1 adaptor related protein complex 5 subunit sigma 1 involved_in ISO (PMID:20613862) RGD PMID:20613862 NCBI chr 3:118,429,618...118,436,256
Ensembl chr 3:118,429,637...118,432,926
JBrowse link
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 involved_in ISO (PMID:20613862) RGD PMID:20613862 NCBI chr12:12,093,834...12,109,043 JBrowse link
G Atm ATM serine/threonine kinase acts_upstream_of_or_within ISO MGI:1857132 (MGI:3836659|PMID:19061978) RGD PMID:19061978 MGI:3836659 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Aunip aurora kinase A and ninein interacting protein involved_in ISS
ISO
GO_REF:0000024
(PMID:29042561)
UniProt
RGD
PMID:29042561 GO_REF:0000024 NCBI chr 5:146,722,157...146,736,233
Ensembl chr 5:146,722,337...146,736,501
JBrowse link
G Blm BLM RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:17349954)
Ensembl
RGD
PMID:17349954 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
IBA
GO_REF:0000107
MGI:2653913|MGI:2653914 (MGI:3511388|PMID:15485900)
GO_REF:0000024
PMID:21873635
(PMID:20729832), (PMID:21719596)
Ensembl
RGD
UniProt
PMID:15485900 PMID:20729832 PMID:21719596 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3511388, RGD:13792537 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in IBA
ISO
PMID:21873635
(PMID:14728600)
RGD PMID:14728600 PMID:21873635 RGD:13792537 NCBI chr10:2,416,259...2,448,364 JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease involved_in ISO (PMID:26833090) RGD PMID:26833090 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:26807646) RGD PMID:26807646 NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442
JBrowse link
G Fan1 FANCD2 and FANCI associated nuclease 1 involved_in ISO (PMID:20603015), (PMID:20603016) RGD PMID:20603015 PMID:20603016 NCBI chr 1:117,915,323...117,945,044
Ensembl chr 1:117,917,099...117,944,977
JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23166748) RGD PMID:23166748 NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401
JBrowse link
G H2ax H2A.X variant histone acts_upstream_of_or_within ISO MGI:2156048 (MGI:2179182|PMID:11934988) RGD PMID:11934988 MGI:2179182 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Helq helicase, POLQ-like involved_in ISO (PMID:19995904) RGD PMID:19995904 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960
JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA
ISO
PMID:21873635
(MGI:3690191|PMID:16278671)
RGD PMID:16278671 PMID:21873635 MGI:3690191, RGD:13792537 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:18026119) RGD PMID:18026119 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911
JBrowse link
G Kash5 KASH domain containing 5 acts_upstream_of_or_within ISO (MGI:5515826|PMID:24062341) RGD PMID:24062341 MGI:5515826 NCBI chr 1:95,668,918...95,691,353
Ensembl chr 1:95,668,886...95,691,368
JBrowse link
G Kdm4d lysine demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) RGD PMID:24550317 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290
JBrowse link
G LOC100362927 replication protein A3-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:45,908,653...45,909,063
Ensembl chr12:45,908,683...45,909,048
JBrowse link
G LOC103690165 checkpoint protein HUS1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor involved_in ISO
IBA
ISS
(PMID:23401855)
(MGI:5437561|PMID:22771120)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:22771120 PMID:23401855 PMID:21873635 GO_REF:0000024 MGI:5437561, RGD:13792537 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008
JBrowse link
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor involved_in IBA
ISO
PMID:21873635
(MGI:5437561|PMID:22771120), (MGI:5525985|PMID:23401855)
(PMID:22771115), (PMID:23401855)
RGD PMID:22771115 PMID:22771120 PMID:23401855 PMID:21873635 MGI:5437561 MGI:5525985, RGD:13792537 NCBI chr20:32,818,219...32,929,577
Ensembl chr20:32,844,951...32,929,600
JBrowse link
G Mcmdc1 minichromosome maintenance deficient domain containing 1 involved_in IBA
ISS
PMID:21873635
GO_REF:0000024
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537
G Meiob meiosis specific with OB-fold involved_in ISS
ISO
GO_REF:0000024
(MGI:5527015|PMID:24068956), (MGI:5538413|PMID:24240703)
UniProt
RGD
PMID:24068956 PMID:24240703 GO_REF:0000024 MGI:5527015 MGI:5538413 NCBI chr10:13,833,170...13,865,684
Ensembl chr10:13,833,750...13,865,046
JBrowse link
G Mms22l MMS22-like, DNA repair protein involved_in IBA
ISO
PMID:21873635
(PMID:21055983), (PMID:21055984), (PMID:21055985)
RGD PMID:21055983 PMID:21055984 PMID:21055985 PMID:21873635 RGD:13792537 NCBI chr 5:38,197,707...38,313,745
Ensembl chr 5:38,197,779...38,313,745
JBrowse link
G Morf4l1 mortality factor 4 like 1 involved_in ISO
ISS
(PMID:20332121)
GO_REF:0000024
RGD
UniProt
PMID:20332121 GO_REF:0000024 NCBI chr 8:90,642,988...90,664,518
Ensembl chr 8:90,642,988...90,664,519
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:29670289), (PMID:30612738)
UniProt
Ensembl
RGD
PMID:29670289 PMID:30612738 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Nabp1 nucleic acid binding protein 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19605351)
UniProt
RGD
PMID:19605351 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107
JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:19605351)
PMID:21873635
UniProt
RGD
PMID:19605351 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:830,949...836,551
Ensembl chr 7:830,949...838,027
JBrowse link
G Nbn nibrin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Nsmce1 NSE1 homolog, SMC5-SMC6 complex component involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:180,030,355...180,058,541
Ensembl chr 1:180,030,160...180,058,417
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
IBA
ISS
IEA
(PMID:16810316)
PMID:21873635
GO_REF:0000024
GO_REF:0000002
RGD
UniProt
InterPro
PMID:16810316 PMID:21873635 GO_REF:0000002 GO_REF:0000024, RGD:13792537 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 involved_in IBA
ISO
PMID:21873635
(PMID:26323318)
RGD PMID:26323318 PMID:21873635 RGD:13792537 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229
JBrowse link
G Palb2 partner and localizer of BRCA2 involved_in ISO
IBA
(PMID:19369211), (PMID:19423707), (PMID:26323318)
PMID:21873635
RGD PMID:19369211 PMID:19423707 PMID:26323318 PMID:21873635 RGD:13792537 NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990
JBrowse link
G Poll DNA polymerase lambda involved_in ISO
ISS
(PMID:20693240)
GO_REF:0000024
RGD
UniProt
PMID:20693240 GO_REF:0000024 NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662
JBrowse link
G Poln DNA polymerase nu involved_in ISO (PMID:19995904) RGD PMID:19995904 NCBI chr14:76,579,983...76,752,460 JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 involved_in ISO (PMID:22909820) RGD PMID:22909820 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 acts_upstream_of_or_within ISO MGI:1929645 (MGI:5428050|PMID:22711701) RGD PMID:22711701 MGI:5428050 NCBI chr 3:140,160,128...140,188,324
Ensembl chr 3:140,160,118...140,188,298
JBrowse link
G Rad51 RAD51 recombinase acts_upstream_of_or_within
involved_in
IEP
ISO
(PMID:16428451)
(PMID:17996710), (PMID:17996711), (PMID:22778135), (PMID:23509288), (PMID:26681308), (PMID:27239033)
(MGI:3511388|PMID:15485900), (MGI:3525800|PMID:15359272)
RGD PMID:15359272 PMID:15485900 PMID:16428451 PMID:17996710 PMID:17996711 More... MGI:3511388 MGI:3525800, RGD:9831188 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in IBA
ISO
PMID:21873635
(PMID:26323318)
RGD PMID:26323318 PMID:21873635 RGD:13792537 NCBI chr 4:159,759,454...159,772,524
Ensembl chr 4:159,759,459...159,772,524
JBrowse link
G Rad51b RAD51 paralog B involved_in IBA
ISO
PMID:21873635
(PMID:23149936)
RGD PMID:23149936 PMID:21873635 RGD:13792537 NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
JBrowse link
G Rad51c RAD51 paralog C involved_in ISO (PMID:23149936) RGD PMID:23149936 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248
JBrowse link
G Rad51d RAD51 paralog D involved_in IBA
ISO
PMID:21873635
(PMID:23149936)
RGD PMID:23149936 PMID:21873635 RGD:13792537 NCBI chr10:67,805,720...67,824,452 JBrowse link
G Rad52 RAD52 homolog, DNA repair protein involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2446961|PMID:12379650)
RGD PMID:12379650 PMID:21873635 MGI:2446961, RGD:13792537 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
G Rad54b RAD54 homolog B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:16428451)
MGI:3617695|MGI:894697 (MGI:3615835|PMID:16428451), (MGI:3836659|PMID:19061978)
RGD PMID:16428451 PMID:19061978 PMID:21873635 MGI:3615835 MGI:3836659, RGD:13792537 NCBI chr 5:25,030,885...25,104,616
Ensembl chr 5:25,032,066...25,104,616
JBrowse link
G Rad54l RAD54 like acts_upstream_of_or_within ISO MGI:2183934|MGI:3605986 (MGI:3615835|PMID:16428451), (MGI:3836659|PMID:19061978) RGD PMID:16428451 PMID:19061978 MGI:3615835 MGI:3836659 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease involved_in IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G Rec8 REC8 meiotic recombination protein acts_upstream_of_or_within ISO MGI:3652039 (MGI:5428050|PMID:22711701) RGD PMID:22711701 MGI:5428050 NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326
JBrowse link
G Recql RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945
JBrowse link
G Recql4 RecQ like helicase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
JBrowse link
G Recql5 RecQ like helicase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099
JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:26474068), (PMID:28575657), (PMID:28575658), (PMID:28691929) RGD PMID:26474068 PMID:28575657 PMID:28575658 PMID:28691929 NCBI chr19:39,235,883...39,268,536
Ensembl chr19:39,236,787...39,268,479
JBrowse link
G RGD1561465 similar to RIKEN cDNA 2900010J23 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:145,014,246...145,014,612
Ensembl chr 5:145,014,261...145,014,509
JBrowse link
G RGD1565844 similar to RIKEN cDNA 1700045I19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:30,739,541...30,740,614
Ensembl chr  X:30,739,413...30,740,613
JBrowse link
G Rmi1 RecQ mediated genome instability 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:6,256,537...6,264,523
Ensembl chr17:6,256,450...6,264,695
JBrowse link
G Rnf138 ring finger protein 138 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:26502055), (PMID:26502057)
UniProt
RGD
PMID:26502055 PMID:26502057 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:12,291,557...12,315,931 JBrowse link
G Rpa1 replication protein A1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17765923)
MGI:3582609 (MGI:3056835|PMID:15470499)
PMID:21873635
RGD PMID:15470499 PMID:17765923 PMID:21873635 MGI:3056835, RGD:13792537 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G Rpa2 replication protein A2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17765923)
UniProt
RGD
PMID:17765923 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350
JBrowse link
G Rpa3 replication protein A3 involved_in IBA
ISO
PMID:21873635
(PMID:17765923)
RGD PMID:17765923 PMID:21873635 RGD:13792537 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:28834754), (PMID:29670289) RGD PMID:28834754 PMID:29670289 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386
JBrowse link
G Sem1 SEM1 26S proteasome subunit involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3525800|PMID:15359272)
RGD PMID:15359272 PMID:21873635 MGI:3525800, RGD:13792537 NCBI chr 4:34,671,848...34,692,005
Ensembl chr 4:34,671,848...34,692,005
JBrowse link
G Sfpq splicing factor proline and glutamine rich acts_upstream_of_or_within ISO (PMID:20813759) RGD PMID:20813759 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sfr1 SWI5-dependent homologous recombination repair protein 1 involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(MGI:4868525|PMID:20976249)
PMID:21873635
GO_REF:0000107
(PMID:21252223)
UniProt
RGD
Ensembl
PMID:20976249 PMID:21252223 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4868525, RGD:13792537 NCBI chr 1:246,619,235...246,623,250
Ensembl chr 1:246,597,044...246,623,250
JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in IBA
ISO
PMID:21873635
(PMID:19595721)
RGD PMID:19595721 PMID:21873635 RGD:13792537 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775
JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:19595721), (PMID:19596235) RGD PMID:19595721 PMID:19596235 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295
JBrowse link
G Smc5 structural maintenance of chromosomes 5 involved_in ISO (PMID:16810316) RGD PMID:16810316 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096
JBrowse link
G Smc6 structural maintenance of chromosomes 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746
JBrowse link
G Spidr scaffold protein involved in DNA repair involved_in IBA
ISO
PMID:21873635
(PMID:23509288)
RGD PMID:23509288 PMID:21873635 RGD:13792537 NCBI chr11:84,766,593...85,007,597
Ensembl chr11:84,766,593...85,007,600
JBrowse link
G Swi5 SWI5 homologous recombination repair protein involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:4868525|PMID:20976249)
(PMID:21252223)
PMID:21873635
UniProt
RGD
PMID:20976249 PMID:21252223 PMID:21873635 GO_REF:0000024 MGI:4868525, RGD:13792537 NCBI chr 3:15,574,687...15,583,760
Ensembl chr 3:15,564,715...15,583,805
JBrowse link
G Swsap1 SWIM-type zinc finger 7 associated protein 1 involved_in IBA
ISO
PMID:21873635
(PMID:21965664)
RGD PMID:21965664 PMID:21873635 RGD:13792537 NCBI chr 8:20,486,680...20,489,213
Ensembl chr 8:20,486,678...20,489,211
JBrowse link
G Tonsl tonsoku-like, DNA repair protein involved_in ISO
ISS
(PMID:21055983), (PMID:21055984), (PMID:21055985), (PMID:30773278)
GO_REF:0000024
RGD
UniProt
PMID:21055983 PMID:21055984 PMID:21055985 PMID:30773278 GO_REF:0000024 NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:17349954) RGD PMID:17349954 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Wdr48 WD repeat domain 48 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3877670 (MGI:5547894|PMID:24001775)
PMID:21873635
RGD PMID:24001775 PMID:21873635 MGI:5547894, RGD:13792537 NCBI chr 8:119,622,053...119,655,264
Ensembl chr 8:119,622,048...119,655,264
JBrowse link
G Wrn WRN RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:23149936)
MGI:3654106 (MGI:3652689|PMID:16777961)
PMID:21873635
RGD PMID:16777961 PMID:23149936 PMID:21873635 MGI:3652689, RGD:13792537 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23149936) RGD PMID:23149936 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (PMID:18026119) RGD PMID:18026119 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zfyve26 zinc finger FYVE-type containing 26 involved_in ISO
IEA
(PMID:20613862)
GO_REF:0000107
RGD
Ensembl
PMID:20613862 GO_REF:0000107 NCBI chr 6:98,031,874...98,095,538
Ensembl chr 6:98,032,520...98,095,480
JBrowse link
G Zswim7 zinc finger, SWIM-type containing 7 involved_in ISO
IBA
(PMID:21965664)
PMID:21873635
RGD PMID:21965664 PMID:21873635 RGD:13792537 NCBI chr10:46,953,311...46,969,800
Ensembl chr10:46,957,525...46,969,671
JBrowse link
double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor involved_in ISO
IEA
(PMID:23689425)
GO_REF:0000107
RGD
Ensembl
PMID:23689425 GO_REF:0000107 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
JBrowse link
G Cyren cell cycle regulator of NHEJ involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(MGI:6202149|PMID:30017584)
(PMID:24610814)
UniProt
RGD
PMID:24610814 PMID:30017584 PMID:21873635 GO_REF:0000024 MGI:6202149, RGD:13792537 NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602
JBrowse link
G Dclre1a DNA cross-link repair 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:255,569,911...255,589,815
Ensembl chr 1:255,569,919...255,589,678
JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423
JBrowse link
G Dclre1c DNA cross-link repair 1C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:74,775,828...74,810,089
Ensembl chr17:74,776,935...74,809,186
JBrowse link
G Dntt DNA nucleotidylexotransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:239,856,391...239,888,283
Ensembl chr 1:239,856,391...239,888,282
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,416,259...2,448,364 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:9600082) RGD PMID:9600082 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Iffo1 intermediate filament family orphan 1 involved_in ISO (PMID:31548606) RGD PMID:31548606 NCBI chr 4:157,945,075...157,962,302
Ensembl chr 4:157,945,107...157,962,302
JBrowse link
G Kdm2a lysine demethylase 2A involved_in ISO (PMID:21187428) RGD PMID:21187428 NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787
JBrowse link
G Lig1 DNA ligase 1 acts_upstream_of_or_within ISO (MGI:5014103|PMID:21655080) RGD PMID:21655080 MGI:5014103 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
JBrowse link
G Lig3 DNA ligase 3 acts_upstream_of_or_within ISO (MGI:5014103|PMID:21655080) RGD PMID:21655080 MGI:5014103 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
G Lig4 DNA ligase 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:Q15554 (PMID:12517771), (PMID:17290226), (PMID:23275564), (PMID:9809069)
(MGI:5705227|PMID:12361565)
MGI:1857720|MGI:1857732 (MGI:1859491|PMID:10823907), (MGI:3652689|PMID:16777961)
RGD PMID:9809069 PMID:10823907 PMID:12361565 PMID:12517771 PMID:16777961 More... MGI:1859491 MGI:3652689 MGI:5705227, RGD:13792537 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857946 (MGI:3039915|PMID:15084308)
Ensembl
RGD
PMID:15084308 GO_REF:0000107 MGI:3039915 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISO
IEA
IBA
(PMID:9651580)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:9651580 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Nhej1 nonhomologous end-joining factor 1 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5807276|PMID:27798842), (MGI:5822993|PMID:28051062)
(PMID:16439204), (PMID:16439205), (PMID:17717001), (PMID:18158905), (PMID:18644470), (PMID:19056826), (PMID:20558749), (PMID:27437582), (PMID:28500754), (PMID:30250067)
GO_REF:0000024
RGD
UniProt
PMID:16439204 PMID:16439205 PMID:17717001 PMID:18158905 PMID:18644470 More... GO_REF:0000024 MGI:5807276 MGI:5822993, RGD:13792537, RGD:8553261 NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase NOT|involved_in ISO (PMID:16810316) RGD PMID:16810316 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899
JBrowse link
G Paxx PAXX, non-homologous end joining factor involved_in IBA
ISO
PMID:21873635
(MGI:5807276|PMID:27798842), (MGI:5822993|PMID:28051062)
(PMID:25574025), (PMID:25670504), (PMID:25941166), (PMID:30250067)
RGD PMID:25574025 PMID:25670504 PMID:25941166 PMID:27798842 PMID:28051062 More... MGI:5807276 MGI:5822993, RGD:13792537 NCBI chr 3:8,274,762...8,276,338
Ensembl chr 3:8,274,762...8,276,521
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO
IEA
(PMID:15385968), (PMID:28453785)
GO_REF:0000107
RGD
Ensembl
PMID:15385968 PMID:28453785 GO_REF:0000107 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in ISO
ISS
(PMID:11470886)
GO_REF:0000024
RGD
UniProt
PMID:11470886 GO_REF:0000024 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Polb DNA polymerase beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Poll DNA polymerase lambda involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:19806195), (PMID:30250067)
PMID:21873635
UniProt
RGD
PMID:19806195 PMID:30250067 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662
JBrowse link
G Polm DNA polymerase mu involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:80,707,075...80,716,677
Ensembl chr14:80,706,345...80,717,086
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO (MGI:5543316|PMID:23836881) RGD PMID:23836881 MGI:5543316 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prpf19 pre-mRNA processing factor 19 involved_in ISO
ISS
(PMID:18263876)
GO_REF:0000024
RGD
UniProt
PMID:18263876 GO_REF:0000024 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 involved_in ISO (PMID:22909820) RGD PMID:22909820 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
JBrowse link
G Rnf8 ring finger protein 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:5293246|PMID:21857671), (MGI:5465398|PMID:22266820)
UniProt
RGD
PMID:21857671 PMID:22266820 GO_REF:0000024 MGI:5293246 MGI:5465398 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491
JBrowse link
G Setmar SET domain and mariner transposase fusion gene involved_in ISO (PMID:16332963), (PMID:18263876), (PMID:21187428), (PMID:24573677) RGD PMID:16332963 PMID:18263876 PMID:21187428 PMID:24573677 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 involved_in ISO (PMID:26089390) RGD PMID:26089390 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146
JBrowse link
G Smc5 structural maintenance of chromosomes 5 NOT|involved_in ISO (PMID:16810316) RGD PMID:16810316 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23333306), (PMID:23760478), (PMID:28241136)
(MGI:5476381|PMID:23333305), (MGI:5887194|PMID:20362325)
RGD PMID:20362325 PMID:23333305 PMID:23333306 PMID:23760478 PMID:28241136 MGI:5476381 MGI:5887194 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:P49917 (PMID:12517771), (PMID:15385968), (PMID:17290226), (PMID:25597996), (PMID:25742519), (PMID:25934149), (PMID:26774286), (PMID:27437582), (PMID:28500754), (PMID:9809069)
MGI:1926771|MGI:3047571|MGI:3641440 (MGI:3761960|PMID:17713479)
(MGI:3758502|PMID:14690602)
RGD PMID:9809069 PMID:12517771 PMID:14690602 PMID:15385968 PMID:17290226 More... MGI:3758502 MGI:3761960, RGD:13792537 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO
IBA
(PMID:20383123), (PMID:26359349)
PMID:21873635
RGD PMID:20383123 PMID:26359349 PMID:21873635 RGD:13792537 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:20383123), (PMID:26359349)
MGI:2179954 (MGI:2155497|PMID:11751629)
PMID:21873635
RGD PMID:11751629 PMID:20383123 PMID:26359349 PMID:21873635 MGI:2155497, RGD:13792537 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
JBrowse link
double-strand break repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad52 RAD52 homolog, DNA repair protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
double-strand break repair via synthesis-dependent strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fancm FA complementation group M involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:83,126,903...83,180,455
Ensembl chr 6:83,127,093...83,180,028
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
late meiotic recombination nodule assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcmdc2 minichromosome maintenance domain containing 2 acts_upstream_of_or_within ISO MGI:2178050|MGI:5511194 (MGI:5805564|PMID:27760146) RGD PMID:27760146 MGI:5805564 NCBI chr 5:9,291,967...9,337,526
Ensembl chr 5:9,298,101...9,338,300
JBrowse link
meiotic DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slx4 SLX4 structure-specific endonuclease subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295
JBrowse link
G Spo11 SPO11, initiator of meiotic double stranded breaks involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:161,755,299...161,770,930
Ensembl chr 3:161,757,519...161,770,925
JBrowse link
meiotic DNA double-strand break processing involved in reciprocal meiotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brip1 BRCA1 interacting helicase 1 acts_upstream_of_or_within ISO MGI:4129733 (MGI:5700253|PMID:26490168) RGD PMID:26490168 MGI:5700253 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Six6os1 Six6 opposite strand transcript 1 involved_in IBA
ISO
PMID:21873635
(MGI:5822939|PMID:27796301)
RGD PMID:27796301 PMID:21873635 MGI:5822939, RGD:13792537 NCBI chr 6:91,579,185...91,615,183
Ensembl chr 6:91,579,325...91,615,148
JBrowse link
meiotic DNA recombinase assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad51c RAD51 paralog C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248
JBrowse link
meiotic recombination nodule assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcmdc2 minichromosome maintenance domain containing 2 acts_upstream_of_or_within ISO MGI:2178050|MGI:5511194 (MGI:5805564|PMID:27760146) RGD PMID:27760146 MGI:5805564 NCBI chr 5:9,291,967...9,337,526
Ensembl chr 5:9,298,101...9,338,300
JBrowse link
mitochondrial double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
negative regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:20725033)
PMID:21873635
UniProt
RGD
PMID:20725033 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:122,545,029...122,563,651
Ensembl chr 6:122,545,061...122,563,644
JBrowse link
G Rnf169 ring finger protein 169 involved_in ISO (PMID:22492721), (PMID:22733822), (PMID:22742833) RGD PMID:22492721 PMID:22733822 PMID:22742833 NCBI chr 1:154,250,462...154,311,867
Ensembl chr 1:154,254,473...154,311,653
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 involved_in ISO
ISS
(PMID:22884692)
GO_REF:0000024
RGD
UniProt
PMID:22884692 GO_REF:0000024 NCBI chr 9:85,916,691...86,043,312
Ensembl chr 9:85,916,691...86,051,403
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:22884692)
Ensembl
UniProt
RGD
PMID:22884692 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903
JBrowse link
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in IBA
ISO
PMID:21873635
(MGI:6241455|PMID:30356214)
(PMID:30356214)
RGD PMID:30356214 PMID:21873635 MGI:6241455, RGD:13792537 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2156841 (MGI:5648586|PMID:25520194)
RGD PMID:25520194 PMID:21873635 MGI:5648586, RGD:13792537 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (PMID:19736316)
(MGI:5566975|PMID:24108124)
RGD PMID:19736316 PMID:24108124 MGI:5566975 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G Helb DNA helicase B involved_in IBA
ISO
PMID:21873635
(MGI:5766842|PMID:26774285)
(PMID:26774285)
RGD PMID:26774285 PMID:21873635 MGI:5766842, RGD:13792537 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G Klhl15 kelch-like family member 15 involved_in ISO (PMID:27561354) RGD PMID:27561354 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Parpbp PARP1 binding protein involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:22153967)
UniProt
Ensembl
RGD
PMID:22153967 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695
JBrowse link
G Polq DNA polymerase theta involved_in ISO (PMID:25642963)
(MGI:5621198|PMID:25642960)
RGD PMID:25642960 PMID:25642963 MGI:5621198 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked involved_in ISO
ISS
(PMID:28735897)
GO_REF:0000024
RGD
UniProt
PMID:28735897 GO_REF:0000024 NCBI chr  X:103,089,284...103,176,840
Ensembl chr  X:103,089,284...103,176,838
JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO MGI:2448558 (MGI:5648586|PMID:25520194) RGD PMID:25520194 MGI:5648586 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23333306)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)
RGD PMID:23306437 PMID:23333305 PMID:23333306 MGI:5468037 MGI:5476381 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Rmi2 RecQ mediated genome instability 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:4,829,333...4,837,264 JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA
(PMID:29656893)
PMID:21873635
RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,294,956...35,301,865 JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23333306), (PMID:23345425)
(MGI:5476381|PMID:23333305), (MGI:5887194|PMID:20362325)
RGD PMID:20362325 PMID:23333305 PMID:23333306 PMID:23345425 MGI:5476381 MGI:5887194 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO (PMID:30612738) RGD PMID:30612738 NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059
JBrowse link
negative regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aunip aurora kinase A and ninein interacting protein involved_in ISS
ISO
GO_REF:0000024
(PMID:29042561)
UniProt
RGD
PMID:29042561 GO_REF:0000024 NCBI chr 5:146,722,157...146,736,233
Ensembl chr 5:146,722,337...146,736,501
JBrowse link
G Cyren cell cycle regulator of NHEJ involved_in ISO
ISS
(PMID:28959974)
GO_REF:0000024
RGD
UniProt
PMID:28959974 GO_REF:0000024 NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19549901)
UniProt
RGD
PMID:19549901 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:26359349) RGD PMID:26359349 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 involved_in ISO (PMID:28241136) RGD PMID:28241136 NCBI chr10:10,636,174...10,638,090
Ensembl chr10:10,636,174...10,688,370
JBrowse link
negative regulation of double-strand break repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogg1 8-oxoguanine DNA glycosylase acts_upstream_of_or_within ISO (PMID:19506022) RGD PMID:19506022 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
positive regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx11 DEAD/H-box helicase 11 involved_in ISO (PMID:23797032) RGD PMID:23797032 NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550
JBrowse link
G Fmn2 formin 2 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr13:86,454,256...86,771,437 JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA
(PMID:17101782)
GO_REF:0000107
(MGI:3698692|PMID:17101782)
RGD
Ensembl
PMID:17101782 GO_REF:0000107 MGI:3698692 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member involved_in ISS
ISO
GO_REF:0000024
(MGI:6467697|PMID:29125140), (MGI:6716977|PMID:33115731)
UniProt
RGD
PMID:29125140 PMID:33115731 GO_REF:0000024 MGI:6467697 MGI:6716977 NCBI chr 8:73,842,344...73,844,248
Ensembl chr 8:73,842,344...73,844,248
JBrowse link
G LOC100910636 zinc finger CW-type PWWP domain protein 1-like involved_in ISO (MGI:6358520|PMID:31453335), (MGI:6442007|PMID:32374261), (MGI:6443266|PMID:32352380), (MGI:6467709|PMID:32744506) RGD PMID:31453335 PMID:32352380 PMID:32374261 PMID:32744506 MGI:6358520 MGI:6442007 MGI:6443266 MGI:6467709 NCBI chr12:17,798,650...17,812,208 JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase involved_in ISO (PMID:24147153) RGD PMID:24147153 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Ooep oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) RGD PMID:29125140 MGI:6467697 NCBI chr 8:79,223,388...79,224,554
Ensembl chr 8:79,223,375...79,224,541
JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149
JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 involved_in IBA
ISO
PMID:21873635
(PMID:25931565)
RGD PMID:25931565 PMID:21873635 RGD:13792537 NCBI chr 1:243,782,781...243,845,409
Ensembl chr 1:243,782,246...243,845,250
JBrowse link
G Spidr scaffold protein involved in DNA repair involved_in ISO (PMID:23509288) RGD PMID:23509288 NCBI chr11:84,766,593...85,007,597
Ensembl chr11:84,766,593...85,007,600
JBrowse link
G Spire1 spire-type actin nucleation factor 1 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr18:61,041,290...61,171,670
Ensembl chr18:61,041,290...61,171,899
JBrowse link
G Spire2 spire-type actin nucleation factor 2 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr19:51,373,368...51,411,920
Ensembl chr19:51,373,228...51,411,920
JBrowse link
G Timeless timeless circadian regulator involved_in ISO
ISS
(PMID:23797032)
GO_REF:0000024
RGD
UniProt
PMID:23797032 GO_REF:0000024 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO
GO_REF:0000024
(PMID:27715493)
UniProt
RGD
PMID:27715493 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929
JBrowse link
G Zcwpw1 zinc finger CW-type and PWWP domain containing 1 involved_in ISO (MGI:6358520|PMID:31453335), (MGI:6442007|PMID:32374261), (MGI:6443266|PMID:32352380), (MGI:6467709|PMID:32744506) RGD PMID:31453335 PMID:32352380 PMID:32374261 PMID:32744506 MGI:6358520 MGI:6442007 MGI:6443266 MGI:6467709 NCBI chr12:18,880,625...18,910,713
Ensembl chr12:18,880,633...18,910,711
JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 involved_in ISO
ISS
(PMID:29925947)
GO_REF:0000024
RGD
UniProt
PMID:29925947 GO_REF:0000024 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
JBrowse link
G Arid2 AT-rich interaction domain 2 involved_in ISO (PMID:28381560) RGD PMID:28381560 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512
JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:2448558 (MGI:5648586|PMID:25520194) RGD PMID:25520194 MGI:5648586 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1328362 (MGI:5648586|PMID:25520194)
RGD PMID:25520194 PMID:21873635 MGI:5648586, RGD:13792537 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Fus FUS RNA binding protein involved_in ISO (PMID:10567410) RGD PMID:10567410 NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member involved_in ISO
ISS
(PMID:31609975)
(MGI:6716962|PMID:25936915)
GO_REF:0000024
RGD
UniProt
PMID:25936915 PMID:31609975 GO_REF:0000024 MGI:6716962 NCBI chr 8:73,842,344...73,844,248
Ensembl chr 8:73,842,344...73,844,248
JBrowse link
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component involved_in ISO (PMID:29225034) RGD PMID:29225034 NCBI chr 1:240,757,279...240,794,291
Ensembl chr 1:240,757,282...240,794,288
JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469
JBrowse link
G Ooep oocyte expressed protein involved_in ISO (MGI:6272426|PMID:29955025) RGD PMID:29955025 MGI:6272426 NCBI chr 8:79,223,388...79,224,554
Ensembl chr 8:79,223,375...79,224,541
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
ISS
(PMID:26344098), (PMID:30356214)
GO_REF:0000024
RGD
UniProt
PMID:26344098 PMID:30356214 GO_REF:0000024 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in ISO (PMID:17996710), (PMID:17996711) RGD PMID:17996710 PMID:17996711 NCBI chr 4:159,759,454...159,772,524
Ensembl chr 4:159,759,459...159,772,524
JBrowse link
G Timeless timeless circadian regulator involved_in ISO
ISS
(PMID:26344098), (PMID:30356214)
GO_REF:0000024
RGD
UniProt
PMID:26344098 PMID:30356214 GO_REF:0000024 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO (PMID:29925947) RGD PMID:29925947 NCBI chr  X:14,405,096...14,413,850
Ensembl chr  X:14,405,124...14,413,849
JBrowse link
G Wdr48 WD repeat domain 48 involved_in ISO (PMID:27239033), (PMID:27463890) RGD PMID:27239033 PMID:27463890 NCBI chr 8:119,622,053...119,655,264
Ensembl chr 8:119,622,048...119,655,264
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISO
ISS
(PMID:25512560)
GO_REF:0000024
RGD
UniProt
PMID:25512560 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929
JBrowse link
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:64,814,926...64,824,538
Ensembl chr11:64,814,926...64,824,538
JBrowse link
G Fh fumarate hydratase involved_in ISO
ISS
(PMID:26237645)
GO_REF:0000024
RGD
UniProt
PMID:26237645 GO_REF:0000024 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Kdm4d lysine demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) RGD PMID:24550317 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290
JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO
GO_REF:0000024
(PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819
JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO
ISS
(PMID:28114273)
GO_REF:0000024
RGD
UniProt
PMID:28114273 GO_REF:0000024 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (PMID:24598253) RGD PMID:24598253 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:12032095) RGD PMID:12032095 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:26237645) RGD PMID:26237645 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:28241136)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)
RGD PMID:23306437 PMID:23333305 PMID:28241136 MGI:5468037 MGI:5476381 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Setmar SET domain and mariner transposase fusion gene involved_in ISO (PMID:20620605), (PMID:21491884) RGD PMID:20620605 PMID:21491884 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197
JBrowse link
G Shld1 shieldin complex subunit 1 involved_in IBA
ISO
PMID:21873635
(PMID:29656893)
RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893), (PMID:29789392) RGD PMID:29656893 PMID:29789392 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,294,956...35,301,865 JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
JBrowse link
G Top2b DNA topoisomerase II beta IMP RGD PMID:22019940 RGD:13432143 NCBI chr15:9,051,661...9,111,220
Ensembl chr15:9,051,341...9,112,085
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO
GO_REF:0000024
(PMID:25512560)
UniProt
RGD
PMID:25512560 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929
JBrowse link
regulation of DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Helb DNA helicase B involved_in ISO (PMID:26774285)
(MGI:5766842|PMID:26774285)
RGD PMID:26774285 MGI:5766842 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G Wdr70 WD repeat domain 70 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:56,951,345...57,191,244
Ensembl chr 2:56,951,355...57,191,187
JBrowse link
regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dek DEK proto-oncogene involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:21653549)
RGD PMID:21653549 PMID:21873635 RGD:13792537 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:21639834) RGD PMID:21639834 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:85,916,691...86,043,312
Ensembl chr 9:85,916,691...86,051,403
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903
JBrowse link
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek1 checkpoint kinase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15665856)
UniProt
RGD
PMID:15665856 GO_REF:0000024 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Fignl1 fidgetin-like 1 involved_in ISO
ISS
(PMID:23754376)
GO_REF:0000024
RGD
UniProt
PMID:23754376 GO_REF:0000024 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455
JBrowse link
G Kdm1a lysine demethylase 1A acts_upstream_of_or_within ISO (PMID:24217620) RGD PMID:24217620 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:20154705)
Ensembl
UniProt
RGD
PMID:20154705 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,392,899...181,399,703
Ensembl chr 1:181,392,923...181,399,659
JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 involved_in ISO (PMID:20154705) RGD PMID:20154705 NCBI chr 4:133,454,555...133,495,486
Ensembl chr 4:133,454,555...133,495,486
JBrowse link
G Rad51 RAD51 recombinase involved_in ISO (PMID:23754376) RGD PMID:23754376 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in ISO (PMID:23754376) RGD PMID:23754376 NCBI chr 4:159,759,454...159,772,524
Ensembl chr 4:159,759,459...159,772,524
JBrowse link
G Rpa2 replication protein A2 involved_in ISO
ISS
(PMID:20154705)
GO_REF:0000024
RGD
UniProt
PMID:20154705 GO_REF:0000024 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000104
PMID:21873635
(PMID:18957201)
UniProt
RGD
PMID:18957201 PMID:21873635 GO_REF:0000024 GO_REF:0000104, RGD:13792537 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase involved_in ISO (PMID:24843002) RGD PMID:24843002 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:19135889) RGD PMID:19135889 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Spidr scaffold protein involved in DNA repair involved_in ISO (PMID:23754376) RGD PMID:23754376 NCBI chr11:84,766,593...85,007,597
Ensembl chr11:84,766,593...85,007,600
JBrowse link
G Terf2ip TERF2 interacting protein involved_in ISS
ISO
GO_REF:0000024
(MGI:4440768|PMID:20339076)
UniProt
RGD
PMID:20339076 GO_REF:0000024 MGI:4440768 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064
JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated acts_upstream_of_or_within ISO MGI:3526165 (MGI:3794139|PMID:18283110) RGD PMID:18283110 MGI:3794139 NCBI chr16:58,598,991...58,659,005
Ensembl chr16:58,598,989...58,658,467
JBrowse link
G Usp51 ubiquitin specific peptidase 51 involved_in ISO (PMID:27083998) RGD PMID:27083998 NCBI chr  X:18,374,940...18,381,472
Ensembl chr  X:18,376,930...18,379,888
JBrowse link
G Zfp365 zinc finger protein 365 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:23966166)
UniProt
RGD
PMID:23966166 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:20,666,240...20,689,734
Ensembl chr20:20,666,240...20,691,238
JBrowse link
regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 NOT|involved_in ISS
ISO
GO_REF:0000024
(PMID:29925947)
UniProt
RGD
PMID:29925947 GO_REF:0000024 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
JBrowse link
G Dek DEK proto-oncogene acts_upstream_of_or_within ISO MGI:3838711 (MGI:5317387|PMID:21653549) RGD PMID:21653549 MGI:5317387 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (MGI:5462481|PMID:23241889) RGD PMID:23241889 MGI:5462481 NCBI chr14:76,833,194...76,911,304
Ensembl chr14:76,835,637...76,913,641
JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:29227966) RGD PMID:29227966 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
JBrowse link
G Sirt7 sirtuin 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5789069|PMID:27225932)
UniProt
RGD
PMID:27225932 GO_REF:0000024 MGI:5789069 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172
JBrowse link
G Usp51 ubiquitin specific peptidase 51 involved_in ISO (PMID:27083998) RGD PMID:27083998 NCBI chr  X:18,374,940...18,381,472
Ensembl chr  X:18,376,930...18,379,888
JBrowse link
G Was WASP actin nucleation promoting factor NOT|involved_in ISO (PMID:29925947) RGD PMID:29925947 NCBI chr  X:14,405,096...14,413,850
Ensembl chr  X:14,405,124...14,413,849
JBrowse link
replication-born double-strand break repair via sister chromatid exchange term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO (MGI:5648566|PMID:25597246) RGD PMID:25597246 MGI:5648566 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5648586|PMID:25520194)
RGD PMID:25520194 PMID:21873635 MGI:5648586, RGD:13792537 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
JBrowse link
G Rad21 RAD21 cohesin complex component involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:140,160,128...140,188,324
Ensembl chr 3:140,160,118...140,188,298
JBrowse link
G Rad51 RAD51 recombinase acts_upstream_of_or_within ISO MGI:5444025|MGI:5444027 (MGI:5442243|PMID:22778135) RGD PMID:22778135 MGI:5442243 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rec8 REC8 meiotic recombination protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326
JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) RGD PMID:25520194 MGI:5648586 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO (PMID:28002403) RGD PMID:28002403 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      cellular metabolic process 10717
        cellular macromolecule metabolic process 8204
          DNA metabolic process 883
            DNA repair 488
              double-strand break repair 255
                DNA double-strand break processing + 20
                double-strand break repair involved in meiotic recombination 8
                double-strand break repair via homologous recombination + 143
                double-strand break repair via nonhomologous end joining + 69
                double-strand break repair via single-strand annealing + 8
                mitochondrial double-strand break repair + 1
                negative regulation of double-strand break repair + 31
                positive regulation of double-strand break repair + 44
                regulation of double-strand break repair + 86
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      cellular metabolic process 10717
        cellular aromatic compound metabolic process 5596
          nucleobase-containing compound metabolic process 5378
            nucleic acid metabolic process 4888
              DNA metabolic process 883
                DNA repair 488
                  double-strand break repair 255
                    DNA double-strand break processing + 20
                    double-strand break repair involved in meiotic recombination 8
                    double-strand break repair via homologous recombination + 143
                    double-strand break repair via nonhomologous end joining + 69
                    double-strand break repair via single-strand annealing + 8
                    mitochondrial double-strand break repair + 1
                    negative regulation of double-strand break repair + 31
                    positive regulation of double-strand break repair + 44
                    regulation of double-strand break repair + 86
paths to the root