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ONTOLOGY REPORT - ANNOTATIONS


Term:single strand break repair
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Accession:GO:0000012 term browser browse the term
Definition:The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.



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single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor involved_in ISO (PMID:17396150) RGD PMID:17396150 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
JBrowse link
G Aptx aprataxin involved_in ISO
IBA
(PMID:17519253)
(MGI:3665365|PMID:16964241)
PMID:21873635
(PMID:14755728)
RGD PMID:14755728 PMID:16964241 PMID:17519253 PMID:21873635 MGI:3665365, RGD:13792537 NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:29545921) RGD PMID:29545921 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in ISO (PMID:29545921) RGD PMID:29545921 NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859
JBrowse link
G Lig4 DNA ligase 4 involved_in ISO (PMID:8798671) RGD PMID:8798671 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:20097625) RGD PMID:20097625 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3818340 (MGI:3763975|PMID:17948061), (MGI:3763978|PMID:17914460)
(PMID:15811850), (PMID:17600775)
RGD PMID:15811850 PMID:17600775 PMID:17914460 PMID:17948061 PMID:21873635 MGI:3763975 MGI:3763978, RGD:13792537 NCBI chr 6:119,163,192...119,231,029
Ensembl chr 6:119,163,166...119,231,021
JBrowse link
G Tnp1 transition protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:12743712)
UniProt
RGD
PMID:12743712 GO_REF:0000024 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274
JBrowse link
G Trpc2 transient receptor potential cation channel subfamily C member 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:156,460,009...156,473,039
Ensembl chr 1:156,440,305...156,473,073
JBrowse link
G Xndc1 Xrcc1 N-terminal domain containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:156,440,284...156,460,609 JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
positive regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO UniProtKB:P18887 (PMID:28002403)
UniProtKB:Q60596 (MGI:5902647|PMID:28002403)
RGD PMID:28002403 MGI:5902647 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO UniProtKB:P09874 (PMID:28002403)
UniProtKB:P11103 (MGI:5902647|PMID:28002403)
RGD PMID:28002403 MGI:5902647 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly (ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO (MGI:5616996|PMID:25378300) RGD PMID:25378300 MGI:5616996 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      cellular metabolic process 9831
        cellular macromolecule metabolic process 3481
          DNA metabolic process 999
            DNA repair 512
              single strand break repair 12
                negative regulation of single strand break repair + 0
                positive regulation of single strand break repair + 2
                regulation of single strand break repair + 2
                single-strand break repair via homologous recombination + 0
                telomere single strand break repair + 0
Path 2
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      cellular metabolic process 9831
        cellular aromatic compound metabolic process 5651
          nucleobase-containing compound metabolic process 5422
            nucleic acid metabolic process 4890
              DNA metabolic process 999
                DNA repair 512
                  single strand break repair 12
                    negative regulation of single strand break repair + 0
                    positive regulation of single strand break repair + 2
                    regulation of single strand break repair + 2
                    single-strand break repair via homologous recombination + 0
                    telomere single strand break repair + 0
paths to the root