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ONTOLOGY REPORT - ANNOTATIONS

Term:single strand break repair
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Accession:GO:0000012 term browser browse the term
Definition:The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.


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single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor involved_in ISO (PMID:17396150) RGD PMID:17396150 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Aptx aprataxin involved_in ISO
IEA
IBA		 (PMID:14755728)
GO_REF:0000107
(PMID:15044383), (PMID:17519253)
(MGI:3665365|PMID:16964241)
PMID:21873635		 RGD
Ensembl		 PMID:14755728 PMID:15044383 PMID:16964241 PMID:17519253 PMID:21873635 GO_REF:0000107 MGI:3665365, RGD:13792537 NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:29545921) RGD PMID:29545921 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in ISO (PMID:29545921) RGD PMID:29545921 NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859 		JBrowse link
G Lig4 DNA ligase 4 involved_in ISO (PMID:8798671) RGD PMID:8798671 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:20097625)
GO_REF:0000107		 RGD
Ensembl		 PMID:20097625 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:15811850), (PMID:17600775)
GO_REF:0000107
MGI:3818340 (MGI:3763975|PMID:17948061), (MGI:3763978|PMID:17914460)		 RGD
Ensembl		 PMID:15811850 PMID:17600775 PMID:17914460 PMID:17948061 GO_REF:0000107 MGI:3763975 MGI:3763978 NCBI chr 6:119,163,192...119,231,029
Ensembl chr 6:119,163,166...119,231,021 		JBrowse link
G Tnp1 transition protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12743712)		 UniProt
RGD		 PMID:12743712 GO_REF:0000024 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274 		JBrowse link
G Trpc2 transient receptor potential cation channel subfamily C member 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:156,460,009...156,473,039
Ensembl chr 1:156,440,305...156,473,073 		JBrowse link
G Xndc1 Xrcc1 N-terminal domain containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:156,440,284...156,460,609 JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
positive regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO UniProtKB:P18887 (PMID:28002403)
UniProtKB:Q60596 (MGI:5902647|PMID:28002403)		 RGD PMID:28002403 MGI:5902647 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO UniProtKB:P09874 (PMID:28002403)
UniProtKB:P11103 (MGI:5902647|PMID:28002403)		 RGD PMID:28002403 MGI:5902647 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly (ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO (MGI:5616996|PMID:25378300) RGD PMID:25378300 MGI:5616996 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular response to stimulus 8778
        cellular response to stress 2097
          DNA damage response 830
            DNA repair 525
              single strand break repair 12
                negative regulation of single strand break repair + 0
                positive regulation of single strand break repair + 2
                regulation of single strand break repair + 2
                single-strand break repair via homologous recombination + 0
                telomere single strand break repair + 0
Path 2
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      cellular metabolic process 10124
        cellular aromatic compound metabolic process 5773
          nucleobase-containing compound metabolic process 5539
            nucleic acid metabolic process 4966
              DNA metabolic process 993
                DNA repair 525
                  single strand break repair 12
                    negative regulation of single strand break repair + 0
                    positive regulation of single strand break repair + 2
                    regulation of single strand break repair + 2
                    single-strand break repair via homologous recombination + 0
                    telomere single strand break repair + 0
paths to the root