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ONTOLOGY REPORT - ANNOTATIONS

Term:UV-damage excision repair
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Accession:GO:0070914 term browser browse the term
Definition:A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).
Synonyms:exact_synonym: UV-damaged DNA endonuclease-dependent excision repair;   UVDE-dependent excision repair;   UVER
 related_synonym: AER;   alternative excision repair


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UV-damage excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr5 actin related protein 5 involved_in ISO (PMID:20855601) RGD PMID:20855601 NCBI chr 3:147,282,461...147,295,870
Ensembl chr 3:147,282,624...147,296,110 		JBrowse link
G Cul4b cullin 4B involved_in ISO (PMID:22334663) RGD PMID:22334663 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:14751237), (PMID:22334663)		 Ensembl
RGD		 PMID:14751237 PMID:22334663 GO_REF:0000107 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 involved_in ISO (PMID:14751237), (PMID:22334663) RGD PMID:14751237 PMID:22334663 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G H2ac25 H2A clustered histone 25 involved_in ISO (PMID:22334663) RGD PMID:22334663 NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20855601) RGD PMID:20855601 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Mc1r melanocortin 1 receptor involved_in ISO (PMID:18292087) RGD PMID:18292087 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:20670893)
GO_REF:0000107		 RGD
Ensembl		 PMID:20670893 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor involved_in ISO (PMID:8077226)
(MGI:5427285|PMID:22431748)		 RGD PMID:8077226 PMID:22431748 MGI:5427285 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
DNA synthesis involved in UV-damage excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 DNA polymerase alpha 1, catalytic subunit NOT|involved_in ISO
ISS		 (PMID:1730053)
GO_REF:0000024		 RGD
UniProt		 PMID:1730053 GO_REF:0000024 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:5562498|PMID:23993650) RGD PMID:23993650 MGI:5562498 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    response to stimulus 10408
      response to stress 4215
        cellular response to stress 2097
          DNA damage response 830
            DNA repair 525
              UV-damage excision repair 14
                DNA synthesis involved in UV-damage excision repair 3
Path 2
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      cellular metabolic process 10124
        cellular aromatic compound metabolic process 5773
          nucleobase-containing compound metabolic process 5539
            nucleic acid metabolic process 4966
              DNA metabolic process 993
                DNA repair 525
                  UV-damage excision repair 14
                    DNA synthesis involved in UV-damage excision repair 3
paths to the root